1.Effect of smoking on the blood lipid level of male patients with type 2 diabetes
Jia LIU ; Youmin WANG ; Shuangshuang FENG
Acta Universitatis Medicinalis Anhui 2015;(2):198-201
Objective To explore the effect of smoking on the triglyceride ( TG ) , cholesterol ( TC ) , high density lipoprotein-cholesterol(HDL-C) and low density lipoprotein-cholesterol(LDL-C) with the male type 2 diabetes. Methods Selected 144 male patients with type 2 diabetes, then divided them into four groups, including non-smokers, former smokers,current mild(≤20 per day) smokers and current heavy ( >20 per day) smokers. All of them were investigated about the age, diabetes pathogenesis, exercise, diet, smoking, lipid-lowering drugs used and checked with TG, TC, HDL-C, LDL-C and so on. The difference of TG, TC, HDL-C, LDL-C among these four groups was compared by the methods of covariance analysis, regression analysis and partial correlation to evalu-ate the relationships of smoking with blood lipid. Results TG of heavy smokers was higher than the non-smokers and HDL-C was lower after correcting the effects of other possibly relative factors(P<0. 05). HDL-C of the former smokers was higher than smokers and TG was lower than heavy smokers(P<0. 05). Smoking was an independent risk factor for HDL-C ( P<0. 05 ,β= -0. 213 ) , and there was a significantly negative relationship between daily cigarette consumption and HDL-C ( r= -0. 223 , P<0. 05 ) . Conclusion Smoking is an important risk factor for the diabetic male patients’ metabolism of the TG and HDL-C,independent of age, body mass index, blood pres-sure,exercise,diabetes pathogenesis, percentage of body fat and blood glucose. Smoking promotes the type 2 diabet-ics’ disorder of blood lipid and smoking cessation is of significance for the diabetics’ regulation of blood lipids.
2.Intervention Effects of Pollen Typhae Total Flavone on INS-1 PancreaticβCells Damage Induced by Palmitic Acid
Xiaotao FENG ; Jia LIU ; Ning LIANG
Journal of Guangzhou University of Traditional Chinese Medicine 2015;(5):899-902,913
Objective To investigate the effects of Pollen Typhae total flavone (PTF) on INS-1 pancreaticβcell damage induced by palmitic acid ( PA) . Methods INS-1 pancreatic β cells were given long-term induction with PA to establish the impaired cell model, and then were intervened with PTF. Cell viability was determined by tetrazolium salt ( XTT) colorimetry. Results PA impaired the viabilities of INS-1 pancreatic β cells in concentration- and time-dependent manner, and PTF improved the impairment of INS-1 pancreatic β cells induced by PA in concentration -dependent manner. Moreover, PTF showed better improvement on the impairment when the INS-1 pancreatic β cells were impaired more seriously by PA. Conclusion PTF has effects on ameliorating the impairment of INS-1 pancreaticβcells induced by PA for long time.
4.Analysis of operative complications in total hip arthroplasty
Lin JIA ; Xuehai LIU ; Yanru FENG
Orthopedic Journal of China 2006;0(12):-
[Objective]To analyse the operative complications in total hip arthroplasty.[Method]Sixty-two patients (62 hips) undergone total hip arthroplasty from March 1998 to November2009,were grouped according to the different causes of the operative complications.[Result]Based on the analysis of all cases,it was found that the most common causes resulting in the failure of the surgery were surgical technichque and fracture,anesthesia,osteoporosis,diabetes mellitus,and cerebral hemorrhage.Complications in all 5 cases were sudden death in 1,femural fracture in 1,unequal-length lower timbs in 1,and postoperative dislocation in 2.[Conclusion]Total hip arthroplasty has been extensively used as an effective procedure for the reconstruction of hip joint.Long-term excellent clinical results are related to preoperative preparation,patient matched fact,and the experience and surgical technique of the surgeon are also of importance to the final outcome.
5.A Retrospective Analysis of 88 Solved Intentional Homicide Cases.
Journal of Forensic Medicine 2016;32(2):119-122
OBJECTIVE:
To summarize the key points, difficulties and relevant practical experiences for analyzing the scene of solved intentional homicide cases.
METHODS:
The data of 88 solved intentional homicide cases in a county from 2004 to 2013 were collected and the retrospective analysis was performed.
RESULTS:
The number of local female victims obviously higher than non-local female victims and the number of non-local suspects is obviously higher than local suspects. The number of Male suspects showed higher compared with the female. Most of them were temporary workers, unemployment or farmers with less education backgrounds. The main causes of victims' death were mechanical injury or asphyxia. The murders were acquaintances in most intentional homicide cases. The motive of the stranger murders was commonly money. The murder behavior types of homicide cases were related with people, money and sexual assault. Camouflage and guilty behavior showed the most significance.
CONCLUSION
The accurate identification of suspects is one of the most important task in forensic investigation and reflects the importance of the criminal scene analysis for intentional homicide cases. It also provides the direction of future research.
Asphyxia
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Cause of Death
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Crime Victims
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Criminals
;
Female
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Homicide/statistics & numerical data*
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Humans
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Male
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Mental Disorders
;
Motivation
;
Retrospective Studies
;
Sex Offenses
6.Influence of induction chemotherapy on target volume and dosimetry of intensity modulated radiotherapy for locally advanced nasopharyngeal carcinoma
Jia WANG ; Feng XIAO ; Feng LIU ; Xuping XI
Chinese Journal of Radiation Oncology 2016;25(5):530-533
As induction chemotherapy goes on,target volume,dose distribution in the surrounding organs at risk (OARs),and target dose conformity all change.Therefore,the question is how to develop reasonable radiotherapy plans in clinical practice.Induction chemotherapy followed by radiotherapy is commonly used around the world,but it is recommended to delineate the target volume based on the gross tumor volume before induction chemotherapy and not to reduce the dose.This point of view lacks the basis of evidence-based medicine.The experts and scholars in China clarify the advantages of radiotherapy plans after induction chemotherapy from the aspects of reducing the target volume,reducing the volume of high-dose region in the target volume,increasing the uniform dose coverage in target volume,reducing dose to OARs,and increasing dose conformity.However,at present,there are no objective data on its long-term efficacy and benefit.Besides,no consensus has been reached on how to delineate the target volume and determine the dose distribution after induction chemotherapy,and further studies are needed.
7.The diagnosis and treatnent of 91 cases of testicular tumor
Hongyan ZHANG ; Feng LIANG ; Zhiling JIA ; Chang LIU ; Duanqi LIU
Cancer Research and Clinic 2011;23(9):607-609
ObjectiveTo summarize the diagnosis,treatment and prognosis of testicular tumor.MethodsThe clinical and followed data of 91 cases of testicular tumor were retrospectively studied. Results In 91 patients, was in 18-40 years old 70.3 % (64/91) and 91.2 % (83/91) cases were germ cell tumor. 18-40years old germ cell tumor was 75.6 % (28/37), there was no case below 17 years old, the older than 60 years was 2.7 %(1/37). The percentage of below 5 years and 18-40 years was 16.1% (5/31) and 67.7 % (21/31),respectively.The interstitial tissue tumor developed in each age section,the number was least.The mixed tumor cases of 18-40 years percent was 93.3 %(14/15).The early symptom of testicular tumor was indolent swelling in one side testis or testis nodus.Combined therapy,including radical orchiectomy,retroperitoneal lymph node dissection, chemotherapy and radiotherapy, were taken. The one year, three years and five years survival rate were 97.3 %, 91.8 %, 91.8 %, respectively. The percentage of Ⅰ, Ⅱ, Ⅲ stage survived 5 years was 83.6 %, 52.3 %, 33.3 %. ConclusionThe peak age of testicular tumor patients was 18-40 years old.The different pathological type is distributed in different ages,and the prognosis is related to pathology and stage. The survival time of germ cell tumor or early stage tumor is longer.
8.Effects of Hot Spring Hydrotherapy on Spasticity of Patients with Incomplete Thoracic Spinal Cord Injury
Zhijie ZHANG ; Chunlong LIU ; Yanan FENG ; Jia LIU ; Jun WANG
Chinese Journal of Rehabilitation Theory and Practice 2009;15(5):472-473
Objective To observe the effect of hot spring hydrotherapy and routine rehabilitation on spasticity of patients with incomplete thoracic spinal cord injury (SCI). Methods 25 patients with incomplete thoracic SCI were divided into hydrotherapy group (n=15) and control group (n=10). The hydrotherapy group received both routine rehabilitation and hydrotherapy,and the control group only underwent routine rehabilitation.They were evaluated with Modified Ashworth Scale (MAS) before and after treatment. Results There was a significant reduction on MAS in both the groups after treatment (P<0.01), and it was more in the hydrotherapy group (P<0.05). Conclusion The hot spring hydrotherapy can facilitate the release of spasticity after incomplete thoracic SCI.
10.Clinical effect of two kinds of infusion jejunum nutrition colostomy of patients after Whipple operation
Shifeng JIA ; Feng YAN ; Hongcheng ZHU ; Guimei JIAO ; Bo LIU
Clinical Medicine of China 2015;31(1):6-9
Objective To compare the effect of enteral nutrition by jejunum colostomy nutrition infusion pump of patients after Whipple surgery as well as reduce adverse reactions in patients.Methods Sixty-five cases with the implementation of Whipple and jejunum of colostomy were selected as our subjects,who were hospitalized in the Affiliated hospital of Hebei United University from Feb.2009 to Nov.2013.All patients were divided into observation group (33 cases) and control group (32 cases) according to the methods of nutrient input.Patients in observation group were given nutrition infusion pump pumping (15 to 50 ml/h) ;and patients in control group were adopted disposable infusion connection infusion with the speed of 30 drops/min with the thermostat heating temperature and the water pipe.The blood glucose,serum albumin,blood electrolyte concentration of postoperative,and the adverse reactions during input nutrient solution including vomiting,abdominal distention,diarrhea and other adverse circumstance were recorded.Results At 1st,3rd,5th day,there was no statistically significant difference in terms of the levels of glucose,blood albumin,blood C1,Na +,K + between two groups(blood glucose:F inner grouP =3.01,P > 0.05 ; F between group =2.90,P > 0.05 ; F cross group =2.87,P > 0.05 ; serum albumin:F inner group =2.94,P > 0.05 ; F between group =2.89,P > 0.05 ; F cross group =2.76,P > 0.05 ; blood Cl:F inner group =1.78,P > 0.05 ; F between group =1.96,P > 0.05 ; F cross group =1.88,P > 0.05 ; blood Na +:F inner group =1.06,P > 0.05 ; F between group =1.35,P > 0.05 ; F cross group =1.27,P > 0.05 ; blood K +:F inner group =3.12,P > 0.05 ; F between group =3.04,P > 0.05 ; F cross group =2.93,P > 0.05).There were significant differences regarding of the rate of vomiting,abdominal distention,diarrhea and other adverse conditions compared with the infusion enteral nutrition has good clinical effect,postoperative blood (x2 =4.029,4.381,4.905 respectively; P < 0.05).Conclusion The methods of colostomy enteral nutrition with infusion pump after Whipple surgery is proved to be with the better clinical effect in reducing postoperative vomiting,abdominal distention,diarrhea and other adverse conditions compared with the infusion enteral nutrition,and there are no significant difference in the terms of the levels of glucose,blood albumin,blood Cl,Na +,K +.