1.Early diagnosis and treatment for deep venous thromboembolism in patients with fracture
Chinese Journal of General Practitioners 2008;7(6):375-377
Objective To explore the measures in early diagnosis and treatment for venous thromboembolism(VTE)in patients with fracture.Methods All the patients with fracture visiting Beijing Jishuitan Hospital in emergency during October 2004 to October 2007 were screened by Well's prediction rules,and anticoagulation and thrombolysis were instituted for those with established diagnosis of VTE by color Doppler ultrasonography and venography.Results Totally,1 508 patients at higg-risk of VTE were identified by D-dimer test.1 455 by color ultrasonography and 53 by venography.Diagnosis of VTE was established in 652 of them(43.2%),619(94.9%)received anticoagulant treatment,162(24.8%)received anticoagulant plus thrombolytie treatment and 25 (3.8%) received anticoagulation plus thrombectomy.In order to prevent fatal pulmonary embolism,vena cava filters(VCFs)were implanted in 146(22.4%)patients,and 33(5.1%)of them were contraindicated to anticoagulation.After treatment,412 cases were cured and 240 were improved,with no one failed.Conclusions Patients with fracture are at high-risk of VTE and should be screened by D-dimer test and color Doppler ultrasonography based on Well's evaluation,as well as by venography for confirming the diagnosis of VTF as appropriate.Anticoagulation and thrombolysis are still the treatment of choice,with thrombectomy and VCF implantation performed only if necessary.
2.On the Academic Thought and Value of Asthenic Diseases in the Bujuji
Journal of Zhejiang Chinese Medical University 2015;(10):771-772,776
Objective]To study Xin'an physician Wu Cheng asthenic diseases related theory of ideas in Bujuji, in order to more comprehensively understand asthenic diseases,to broaden the thinking, enhance the clinical curative effect. [Method]From the academic source of asthenic diseases , syndrome differentiation and treatment,prescription medication,clinical academic value, make research on Wu's thought about asthenic diseases treatment. [Result]Wu Cheng combined with their own perception and experience of clinical evidence, first put forward“external damage caused by asthenic diseases”;Aiming at the asthenic diseases of the treatment,Wu Cheng creatively put forward“support solution method”, “supplementary care method”, “treatment of spleen yin”;Wu Cheng's life was exploring the asthenic diseases,the theory of asthenic diseases had good clinical academic value,not only for the development of the cause of disease theory,but also enriching the theory of health prevention.[Conclusion]Wu Cheng Bujuji rich in content and its syndrome differentiation of asthenic diseases, with much experience, as today, treatment based on the thought of clinical asthenic diseases treatment still has important guiding significance.
8.MRI evaluation of the olfactory pathway.
Xutao MIAO ; Jia LIU ; Yong WEI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(14):1093-1096
MRI scanning is an important technique to evaluate the olfactory system, special scanning parameters could reveal the fine structures of the olfactory pathway. Olfactory cleft, olfactory bulb/tract, olfactory sulcus and olfactory center are the main targets of the scanning. Chronic rhino-sinusitis, head trauma, congenital dysplasia and neural degenerative diseases are the primary causes of the olfactory dysfunction and have particular imaging presentations respectively. Besides indicating the olfactory pathway lesions, MRI could also present the etiology and the prognosis of the olfactory disorder.
Humans
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Magnetic Resonance Imaging
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Olfaction Disorders
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diagnosis
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Olfactory Bulb
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Olfactory Pathways
9.The resistance mechanism and response prediction of docetaxel
Li XIE ; Jia WEI ; Baorui LIU
Cancer Research and Clinic 2009;21(6):427-429
Resistance is one of the most important reasons that restrict the clinical application of most chemotherapeutic medicines. Docetaxel is a very widely applicated antitumor medicine. Most of the researches on the mechanism of resistance against docetaxel focused on the drug transporters, changes in drug metabolism and pathway alteration of cell cycle and apoptnsis. The mechanism of docetaxel resistance and the predictive data based on clinical research to docetaxel therapy in cancer treatment were reviewed.
10.Management of hypogastric artery in endovascular repair of abdominal aortic aneurysm
Jia ZHANG ; Wei GUO ; Xiaoping LIU
Chinese Journal of Interventional Cardiology 2003;0(06):-
Objective To summarize our experiences of management for hypogastric artery in endovascular repair(EVR) of infrarenal abdominal aortic aneurysm(IAAA).Methods From July,1997 to March,2007,62 cases of IAAAs required special management of the internal iliac artery(IIA) during the EVR.Among them,57 cases were type C AAA who included 35 cases of unilateral common iliac artery(CIA) bifurcations and 22 cases of bilateral iliac bifurcations.The remaining 5 cases involved superior iliac bifurcations.Various techniques including simple coverage by stent-graft,embolization of the IIA trunk combined with stent-graft covering,reconstruction of the IIA and combination of the above techniques were applied according to the different conditions of the IIA involved.Results None of the 62 patients required conversion to surgical repair.Immediate post operational angiography demonstrated type Ⅰ endoleak in 6 cases(9.7%).Claudication due to gluteus ischemia occurred in 5 cases(8.1%),leg numbness in 1 case(1.6%),and severe constipation in 1 case(1.6%),but no buttock and colorectal necrosis was recorded.Conclusion It is important to preserve one of the hypogastric arteries and avoid occlusion of both hypogastric arteries in EVR of IAAA.