1.Explore the Quintessence in Traditional Chinese Medicine to Build up a Harmonious Physician-Patient Relationship with Chinese Characteristics
Chinese Medical Ethics 1995;0(02):-
This paper affirms that physician-patient relationship is the most important and fundamental relationship in medical activities.But nowadays there are some unpleasant factors arising in the physician-patient relationship,which have become severe intractable problems and heated social issues to be resolved as soon as possible in the development of Chinese society and healthcare career.Traditional Chinese Medicine contains a lot of information about medical ethics and humanism spirit of medicine.There are also many theories on how to build up a harmonious physician-patient relationship and many viable methods to solve the problems.Analysis of the physician-patient relationship nowadays and exploration of the T.C.M quintessence will help to build up a harmonious physician-patient relationship with Chinese characteristics for the construction of a harmonious society.
2.Reflection on Triage of Casualties Aroused by Wenchuan Earthquake
Chinese Medical Ethics 1995;0(03):-
Researching and discussing the significance,principle,method and ethical conception of triage of casualties during earthquake.In particular,explaining the relationship between triage efficiency and aid impact;Pointing principles in Triage.At last,affirming the exigent importance of education of triage and giving some advie.
3.The evaluation standards and residual value of scrapped medical equipments
Limin JIA ; Pengfei ZHANG ; Peng ZHANG
China Medical Equipment 2016;13(8):102-104,105
Objective:To improve the efficient use of assets, prevent and eliminate the waste and loss.Methods: We improved the standards of medical scrapped evaluation and made full use of the residual value of scrapped equipment for the issues that the program and technical appraisal of medical scrapped evaluation were not standardized, the residual value was not accurate and the disposal was too careless, etc.Results: The residual value was useful for the standard and reasonable approval process of scrapped medical equipment.Conclusion: The perfect disposal process of medical equipment ensures that the fixed assets of hospital are complete and security. Making full use of residual value of the scrapped equipment can increase efficiency of the use of hospital assets and eliminate the waste of assets.
4.Clinical value of risk of ovarian malignancy algorithm in risk stratification of ovarian cancer
Aimin ZHANG ; Li JIA ; Peng ZHANG
Chinese Journal of General Practitioners 2014;13(7):580-582
The serum specimens were collected from ovarian cancer (n =100),benign ovarian disease (n =69) and healthy women (n =95).The serum levels of HE4 and CA125 were detected.Risk of ovarian maliqnancy algorithm (ROMA) was calculated.Accuracy of prediction was evaluated by the area under receiver operating characteristic curve (ROC-AUC).And validity of prediction was evaluated by sensitivity and specificity.The results showed that the median level of ROMA algorithm was 83.0%,8.9% and 8.7% in ovarian cancer,benign ovarian disease and healthy women groups respectively.The difference were statistically significant (all P < 0.01).Compared with benign ovarian disease group,the ROC-AUC of ROMA algorithm was 0.900 in ovarian cancer group.The sensitivity and specificity were 81.0% and 92.8% in ovarian cancer group respectively.Thus ROMA algorithm is a useful parameter in risk stratification for ovarian cancer.The diagnostic accuracy of ROMA algorithm is better than that of HE4 and CA125 in ovarian cancer.
5.Conversion of idiopathic demyelinating optic neuritis to multiple sclerosis: its rate and risks
Xiaojun ZHANG ; Jingting PENG ; Nan JIA
Chinese Journal of Neurology 2009;42(1):20-24
Objective To investigate the clinical prognosis of idiopathic demyelinating optic neuritis (IDON), the rate of its conversion to multiple sclerosis (MS) or neuromyelitis optica (NMO) and its clinical features related to the conversion.Methods Patients satisfying our entry criteria for IDON hospitalized in Beijing Tongren Hospital during the period from 2002 to 2007 were re-evaluated with follow-ups for 6-months to 5-years.The McDonald diagnostic criteria for MS (revised, 2005) was used to diagnose MS in these subjects during follow-up and the diagnosis of NMO utilized 1999 Wingerchuk' s NMO criteria.The Chi-Squared χ2 test was applied to statistically analyze association of clinical features and development of MS or NMO.Results In 107 recruited IDON cases with complete clinical data and follow-up, 12 cases (11.2%) developed into MS or NMO during follow-up period.All 12 cases met the revised McDonald criteria, of which 4 cases met NMO criteria and the remaining eight cases showed some clinical evidence of "optic-spinal MS (OS-MS)".A significantly higher conversion rate of 23.1% was found in recurrent IDON than the 4.4% in single-episode cases (χ2 = 6.899, P < 0.01) .Convesion rate of female patiends (17.2%) is significantly higher than male patients (4.1%, χ2 = 4.620, P < 0.05).Conversion rate of 18.2% in patients with initially abnormal brain MRI was higher than rate of 8.1% in cases with normal brain MRI, but the difference was not statistically significant.No difference was found between presence or absence of swollen disc, nor severity of vision loss.Conclusions In a group of IDON patients, 11.2% developed into MS and NMO or clinically indicative OS-MS.Recurrent IDON and female gender suggested higher risk of developing MS or NMO.
6.Pathogenic Fungi of Blood Culture:Their Distribution and Resistance
Jia PENG ; Weiling FU ; Xiaobing ZHANG
Chinese Journal of Nosocomiology 2005;0(11):-
OBJECTIVE To study the constituent ratio of the pathogenic fungi of blood culture in recent 24 months and their resistance in our hospital.METHODS Blood culture of patients in our hospital was performed by BacT/AlerT120 and the isolated pathogenic fungi were identified by API identified tests(API Inc,France).In(addition) antibiotics sensitivity test was by K-B.RESULTS Of the specimens in 4135 cases,there were 110 strains((2.7%)) with Candida albicans(29%).C.tropicalis(21%) and C.portugal(9%).The(specimens) come from(hepatobilliary)(25%),neurosurgery(24%) and emergency(10%) departments.CONCLUSIONS It is important and necessary to monitor the circumstance of fungal(infection) and resistance of the pathogenic fungi due to its(morbidity) increased.
7.Clinical significance of (18)F-FDG PET-CT in evaluation of the therapeutic efficacy of chemotherapy for lung cancer.
Peng JIA ; Wan-hua GUO ; Ying ZHANG
Chinese Journal of Oncology 2009;31(3):235-236
Adult
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Aged
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Carcinoma, Non-Small-Cell Lung
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diagnostic imaging
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drug therapy
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Female
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Fluorodeoxyglucose F18
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Humans
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Lung Neoplasms
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diagnostic imaging
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drug therapy
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Male
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Middle Aged
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Positron-Emission Tomography
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Small Cell Lung Carcinoma
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diagnostic imaging
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drug therapy
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Tomography, X-Ray Computed
8.The usefulness of complexed prostate-specific antigen in predicting metastasis in patients with prostate cancer
Jingya ZHANG ; Li JIA ; Xiaoqing JIAO ; Peng ZHANG
Chinese Journal of Urology 2015;36(3):209-212
Objective To determine the value of complexed prostate-specific antigen (cPSA) in predicting metastasis in patients with prostate cancer.Methods From January 2012 to April 2014,the clinical data of 74 patients with newly diagnosed prostate cancer in our hospital was retrospective reviewed.The prostate cancer was diagnosed by transrectal ultrasound guided biopsy and postoperative pathologic diagnosis.The patients were divided to 2 groups according to metastases status.There were 38 patients in the group of metastasis and 36 patients in the group of without metastasis.In metastasis group,the bone metastasis was found in 36 cases.There is only one case with lung metastasis and one case with lymph node metastasis.In the group without metastasis,the T stages classification were T1-T2 in 17 cases and T3-T4 in 19 cases.While,10 cases with T1-T2 stage and 28 cases with T3-T4 stage were confirmed in the group with metastasis.There was no statistical significance of T stages and mean age in two groups (P>0.05).The level of cPSA in the serum was detected by chemiluminescent immunoassay,the level of tPSA,fPSA were detected by electro-chemiluminescent immunoassay,fPSA/tPSA,cPSA/tPSA were evaluated and the corresponding specificity were calculated.The correlation of age with tPSA,cPSA were analysed.The differences in PSA,fPSA/tPSA,cPSA/tPSA were compared between metastasis and non-metastasis group.ROC curve analysis was used to determine the diagnostic value of cPSA and tPSA,In the meantime,area of ROC curves were compared by Z test.Results The age was not related to the value of tPSA (r=-0.09,P=0.12) and cPSA(r=-0.38,P=0.14).The median levels of tPSA,fPSA,and cPSA are 29.88μg/L,2.18 μg/L and 18.86 μg/L in the group without metastasis,respectively.The median levels of tPSA,fPSA,and cPSA were 410.05 μg/L,51.50 μ.g/L and 290.40 μg/L in the group with metastasis,respectively.Significant differences of those results could be found in two groups (P<0.05).fPSA/tPSA was 0.07 and cPSA/tPSA was 0.79 in the group without metastasis.fPSA/tPSA was 0.08 and cPSA/tPSA was 0.80 in the group of metastasis.fPSA/tPSA (P=0.77),cPSA/tPSA (P=0.64) in patients with metastasis were not greater than in those without metastasis (P>0.05).The area under the curve of tPSA and cPSA were 0.83 (95% CI 0.73-0.93) and 0.82 (95%CI 0.73-0.92) respectively.Analysis of ROC curves showed that the AUC for cPSA is not significant different from tPSA (Z=1.64,P=0.10).The specificity of cPSA was 22.2% which is higher than that of tPSA (19.4%) at a sensitivity of 92.1% in predicting metastasis comparing with the patients without metastasis.The sensitivity could reach to 90.0% when the cut off value of tPSA was 9μg/L or the cut off value of cPSA was 7 μg/L.Conclusions In our study,a preliminary validation that cPSA is useful for predicting the metastasis in patients with prostate cancer was made.
9.Practice and Thinking about Clinical Pharmacists'Psychological Intervention in SARS Patients
Wei ZHANG ; Dan JIA ; Peng ZHANG ; Yuqin WANG ;
China Pharmacy 2001;0(09):-
OBJECTIVE: To make up the deficiency of pharmacotherapy in the treatment of SARS. METHODS: The psy-chotherapy was carried out by sending drug bag and card, with encouraging and blessing words printed on, to the patients, andthe psychotherapeutic efficacy was investigated by questionaire .RESULTS: 100% of the patients thought our service had goodeffect and was helpful to their psyche and disease, 96.9% of patients thought it was necessary .CONCLUSION: In different wayfrom doctor and nurse's,clinical pharmacist can take part in disease treatment and clinical psychological treatment.
10.Cathepsin L expression in plasma after acute myocardial ischemia and ischemia-reperfusion in rats.
Geng-qian ZHANG ; Zheng LIANG ; Peng YAN ; Xiao-jia ZHANG
Journal of Forensic Medicine 2014;30(4):253-256
OBJECTIVE:
To test cathepsin L as a biomarker of myocardial ischemia by examination of cathepsin L expression in plasma after myocardial ischemia and ischemia-reperfusion in rats.
METHODS:
The rat models were established and divided in acute myocardial ischemia model (myocardial ischemia 30 min, 1 h, 2 h groups), ischemia-reperfusion model (ischemia-reperfusion group), and isoflurane-pretreated ischemia-reperfusion model (isoflurane-pretreated group), respectively. Normal control group and sham-operated group were established as contrast. The contents of cathepsin L in plasma were examined by ELISA and myocardial infarction areas were measured after TTC staining.
RESULTS:
No statistical significant changes were found among the experimental groups compared with the normal control group and sham-operated group (P>0.05). The cathepsin L from the ischemia-reperfusion group increased to 2.37 times compared with the normal control group (P<0.05). The cathepsin L and myocardium infarction size of isoflurane-pretreated group decreased compared with the ischemia-reperfusion group (P<0.05).
CONCLUSION
The cathepsin L in plasma is not a promising biomarker of acute myocardial ischemia. Isoflurane preconditioning can reduce the cathepsin L in plasma caused by ischemia-reperfusion injury.
Animals
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Biomarkers/blood*
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Cathepsin L/analysis*
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Isoflurane
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Myocardial Infarction/metabolism*
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Myocardial Ischemia
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Myocardial Reperfusion Injury/metabolism*
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Myocardium
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Rats