AIM: To analyze and discuss individual combination of femtosecond laser keratectomy excimer laser treatment of myopia clinical effect, thus providing the basis for clinical treatment.
●METHODS:A total of 320 cases (509 eyes) with myopia were divided into the observation group and the control group according to the patient surgery program from Jan. 2010 to Jan. 2015 in the hospital. The observation group were treated with femtosecond laser combined with individual excimer laser keratectomy ( ORK ) treatment. The control group were treated with ORK mechanical knife treatment system valve.
●RESULTS: ln patients with low and moderate myopia, the average visual acuity of observation group and control group were 5.11±0.09 and 5.10±0.08 postoperative 6mo. The average visual acuity of observation group and control group were 5. 09±0. 05 and 5. 08±0. 05 postoperative 6mo in patients with high myopia. After treatment, the visual acuity was improved, and there was no significant difference between the two groups ( P > 0. 05 ). After treatment, the observation group corneal aspherical coefficients Q were significantly lower than the control group (P<0. 05). After treatment, the observation group corneal thickness was significantly thinner than the control group (P<0. 05).
● CONCLUSION: Femtosecond laser combined with individual excimer laser keratectomy for myopia has significant clinical effect and good surgical effectiveness. Also, it′s better to maintain the aspheric shape of the cornea improved the visual quality.

Humans ; Liver Cirrhosis ; diagnosis ; etiology ; therapy

Humans ; Liver Cirrhosis ; diagnosis ; therapy

Autoimmune Diseases ; diagnosis ; therapy ; Humans ; Liver Diseases ; diagnosis ; therapy

Humans ; Liver Failure ; diagnosis ; therapy

Objective To investigate the value of BISAP scoring system in predicting the severity of acute pancreatitis.Methods Medline,EMBASE,Science Direct,Springer link,CBM,Cnki,Wan fang and VIP database were retrieved by computer between January 2000 and March 2013,and articles of BISAP score system in predicting the acute pancreatitis were collected according to strict inclusion criteria.Quality assessment was made by QUADAS scale.Meta-Disc1.4 software was used to analyze the heterogeneity of included articles and perform quantitative synthesis,as well as calculate the pooled sensitivity and specificity,positive likelihood ratio,negative likelihood ratio,and draw the ROC curve,and the results were presented with 95％ CI.Results A total of 11 articles were included,and there were 7 Chinese articles and 4 English articles.According to QUADAS scale,there were 4 articles of A grade,5 articles of B grade,2 articles of C grade.There were 6 studies using 2 as BISAP cut-off value,and 9 articles using 3 as cut-off value,while 4 studies using 2 cut-off values.Pooled analysis showed diagnostic odds ratio of 8.03 (95 ％ CI 5.66-11.38) when cut-off value was 2,and diagnostic odds ratio of 7.49 (95％ CI 5.35-10.49) when cut-off value was 3.There were moderate heterogeneity in both groups (I2 =63.3 ％,P =0.018; I2 =56.1％,P =0.019).When BISAP cut-off value was 2,the pooled analysis of sensitivity,specificity,positive likelihood ratio,negative likelihood ratio and area under curve (AUC) were 59％ (95％ CI56％-63％),82％ (95％ CI 80％-83％),3.50 (95％ CI2.96-4.14),0.45 (95％ CI0.36-0.56) and0.82; and when BISAP cut-off value was 3,the corresponding values were 44％ (95％ CI41％-47％),90％ (95％ CI 89％-91％),4.59 (95％ CI 3.31-6.37),0.64 (95％ CI 0.61-0.68) and 0.64.The former had a high sensitivity,low specificity and large AUC,while the latter had a low sensitivity,high specificity and small AUC.Conclusions The best cut-off value of BISAP in predicting SAP is 2.When cut-off value is 2,the misdiagnosis rate is low,and the false positive rate is in the acceptable range,which is suitable for clinical application.

Humans ; Liver Cirrhosis, Biliary ; diagnosis ; etiology ; therapy

Several reconstruction techniques are available after gastrectomy. Roux-en-Y reconstruction following distal gastrectomy is the reference in terms of long-term functional and endoscopic outcomes. It is the preferred reconstruction for benign lesions and early gastric cancer. In patients with advanced gastric cancer, BillrothII (reconstruction is an acceptable alternative. After total gastrectomy, Roux-en-Y reconstruction is the simplest solution, with satisfactory functional outcome. Addition of a jejunal reservoir seems to improve long-term outcome after total gastrectomy and could be of benefit to patients with good prognosis. After distal or total gastrectomy, hand-sewn anastomoses should be preferred because of lower costs. Mechanical sutures can facilitate transhiatal esophagojejunostomy. After proximal gastrectomy, esophago-gastric anastomosis is the basic reconstruction method. Gastric remnant is made into gastric tube in the operation. The effect of pyloroplasty remains controversial, and further study is needed to improve the quality of life after operation.
Anastomosis, Roux-en-Y ; methods ; Gastrectomy ; Gastroenterostomy ; methods ; Humans ; Reconstructive Surgical Procedures ; methods ; Stomach Neoplasms ; surgery

China ; epidemiology ; Education, Medical, Continuing ; Hepatitis B ; epidemiology ; prevention & control ; Hepatitis B Vaccines ; immunology ; Humans ; Practice Guidelines as Topic ; Vaccination

Angiotensin II Type 1 Receptor Blockers ; therapeutic use ; Antiviral Agents ; therapeutic use ; Biomarkers ; blood ; Biopsy ; Elasticity Imaging Techniques ; Humans ; Liver Cirrhosis ; diagnosis ; etiology ; therapy