1.Radiofrequency catheter oblation in atrial flutter
Ji YAN ; Heping WANG ; Jian XU
Journal of Interventional Radiology 2001;0(06):-
Objective To evaluate the radiofrequency catheter ablation for type I atrial flutter through application of Holo catheter labelling with anatomic imaging localization to ablate the isthmus of IVC TA during complete double way block.Methods Eleven cases with type I atrial flutter undergone Holo catheter labelling technique and consecution with conduction time change of coronary venous sinus orifice withright atrial lower lateral wall pace excitation ,were performed with radiofrequency catheter ablation for the isthmus outcoming with complete double way conduction block. Results All together 11 cases with 4 of atrial flutter and 7 of sinus rhythm were undergone radiofrequency catheter ablation resulting with double way conduction block of the isthmus accompanied by prolongation of right atrial conduction time 56.0?2.3ms and 53.0?4.6ms respectively.The right atrial excitation consecution during coronary venous sinus orifice and right atrial lower lateral wall pace excitation appeared to be in clockwise and counter clockwise of single direction. No recurrence occurred during 3-34 months follow up with only one showing atrial fibrollation.Conclusions The application of Holo catheter labelling technique with anatomic imaging localization to achrieve the double way conduction block by radiofrequency catheter ablation of TVC TA isthmus, is a reliable method for treating atrial flutter.
4.A child with progressive pigmented purpuric dermatosis.
Xia WANG ; Huan YE ; Ji-yan ZHENG
Chinese Journal of Pediatrics 2005;43(10):798-799
Adolescent
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Humans
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Male
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Pigmentation Disorders
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pathology
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Skin
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pathology
6.Cerebral CTPI and head and neck CTA feature of patients with transient cerebral ischemia and its correlation with clinic
Weidong JI ; Yan FANG ; Suishan WANG
Chinese Journal of Primary Medicine and Pharmacy 2015;22(3):382-385
Objective To investigate the head and neck CTA findings and cerebral CTPI in patients with transient ischemic attack (TIA),and their relationship with frequency of TIA,duration and CTA detected responsible vessels.Methods 180 TIA patients were selected as the research subjects,the GE Lightspeed 64 spiral CT perfusion CT scan and CTA examination were taken,and the differences in CTPI parameters measurement,head and neck artery disease of patients were analyzed.To observe the correlation between CTPI perfusion abnormalities in patients with TIA seizure frequency,duration and NIHSS score.The CTPI perfusion abnormalities and consistency of CTA display of responsible vessels were analyzed.Results The positive rate of CTPI examination was 75.56%,that of CTA examination was 81.11%.The positive rate of patients(NIHSS ≥4 points) with CTPI was 88.89%,which was higher than 66.67 % in patients (NIHSS < 4 points) with CTPI (x2 =6.87,P < 0.05).The positive rate of patients (seizures time ≥ 10min) with CTPI TIA was 71.43%,which was higher than 45.45 % of the patients (seizures time < 10m in) with CTPI (x2 =7.23,P < 0.05).The CTPI positive rate of patients with the TIA seizure frequency ≥ 2 times/d was 83.33%,which was higher than 61.67% of patients with the seizure frequency < 2 times/d(x2 =5.48,P < 0.05).The CTPI positive and CTA responsibility vascular consistent proportion was 73.33 %,which was significantly higher than 26.67% of both inconsistent and negative (x2 =19.43,P < 0.01).Conclusion The cerebral CTPI and head and neck CTA can response to TIA in patients with intracranial lesions accurately,consistency and clinical manifestations are very good,which have higher value in clinical application.
7.Effects of statins atorvastatin calcium on cerebral carotid atherosclerotic plaque and efficacy of C-reactive protein
Weidong JI ; Yan FANG ; Jingzhong WANG
Chinese Journal of Primary Medicine and Pharmacy 2014;(17):2587-2588
Objective To investigate the clinical efficacy of statins atorvastatin calcium on cerebral carotid atherosclerotic plaques in patients and the effects on C-reactive protein .Methods 76 patients admitted to hospital with cerebral carotid atherosclerotic plaques in patients randomized manner using its divided into the observation group and control group of 38 patients in the control group not using statins , given only hospital conventional therapy , observed in the control group were given atorvastatin group based on calcium statin treatment ,post-treatment comparison groups the size of carotid atherosclerotic plaque and plasma C-reactive protein changes .Results After treatment , plaque size(0.069 ±0.021)cm2,IMT was (1.29 ±0.28)mm,significantly less than before treatment,after treatment difference was statistically significant (t=7.538,7.132,all P<0.05)also significantly less than the control group ,the difference was statistically significant (t=7.131,6.372,all P<0.05);the observation group after treatment C-reactive protein(3.54 ±1.92 ) mg/L, significantly lower than before treatment , before and after treatment difference was statistically significant(t=6.831,P<0.05),and significantly lower than the control group ,the difference was also statistically significant(t=7.125,P<0.05).Conclusion For patients with cerebral carotid atherosclerotic plaque is concerned,the application of atorvastatin calcium treatment can not only effectively reduce plaque area , but also reduce C-reactive protein,and therefore worthy of further clinical application .
8.Prevention and Management of Deep Fungal Infection by Fluconazole in the Patients with Severe Acute Pancreatitis
Jun YAN ; Chunhai GUO ; Ji WANG
Chinese Journal of Nosocomiology 2006;0(05):-
OBJECTIVE To investigate the clinical character of patients with severe acute pancreatitis(SAP)(infected) with deep fungal organisms and its prevention and treatment with fluconazole.METHODS Among 256(patients) with SAP,46 cases with SAP and deep fungal infection treated by fluconazole were selected as(fluconazole) treatment group,66 patients with suspicious deep fungal infection were randomized into 2 groups: fluconazole(prevention) group(42 cases) and control group(24 cases).RESULTS There were lower incidences of deep fungal(infection) in fluconazole prevention group than that in control one(P
9.Effect of ginaton on renal tubular epithelial cell apoptosis induced by renal ischemia/reperfusion
Yan WANG ; Huaixue JI ; Shuhua XING
Chinese Pharmacological Bulletin 2003;0(08):-
Aim To investigate the effects of ginaton on tubular cell apoptosis in a rat model of renal ischemia/reperfusion(I/R) injury.Methods The model of bilateral post-ischemic renal injury was established by clamping renal pedicles for 45 minutes.To explore the effects of ginaton on activation and expression of JNK and c-Jun,p-JNK1/2,JNK,p-c-Jun,c-Jun were examined by Western blotting.Apoptosis of renal tubular epithelial cells was assessed by terminal deoxynucleotidyl transferase mediated dUTPnick end labeling(TUNEL) and flow cytometric analysis.Results Phosphorylation levels of the JNK and the c-Jun were significantly increased at 20 min after renal I/R injury.This corresponds to a significant increase of apoptotic tubular cells induced by renal I/R injury.Ginaton attenuated the increased phosphorylation of p-JUK at 20 min(vs I/R 20 min,P
10.The role of CD2 in acute rejection after small bowel transplantation in rats
Gang JI ; Yan LIN ; Weizhong WANG
Chinese Journal of Organ Transplantation 2003;0(01):-
Objective To investigate the expression of CD2 in peripheral blood T lymphocytes in acute rejection after small bowel transplantation (SBT) in rats.Methods Three groups were set up: Group A (n=18), receiving sham operation and feeding of common feedstuff; Group B (n=18) receiving SD rat to SD rat iso-series SBT and the treatment of routine liquid infusion and antibiotics after operation; Group C (n=18) receiving SD rat to Wistar rat taniso-series SBT and the same post- operation treatments as in group B. Samples of grafts and peripheral blood in the three groups were collected on the day 3, 5 and 7 respectively after SBT for detection of flow cytometry. The intestinal grafts were obtained for pathological examination.Results The survival time of rats in group C, group B and group A was 7.0? 2.1, 33.3? 2.3 and more than 90 days, respectively. There was significant difference between group C and groups A, B (P