1.Air Particle Concentration and Meteorological Factors
Ying JI ; Huijie FAN ; Qiufang WANG
Journal of Environment and Health 1989;0(06):-
Many researches have shown that atmosphere pollution and meteorological factors are related closely. The relations between the particle concentration in atmosphere and meteorological factors including wind speed,wind direction,air pressure,temperature,humidity,precipitation and atmosphere stability vary in different researches. Taking into consideration the complexity of meteorological factors and the components and concentration index of particles,it is more reasonable to do multi-factor analysis. But the results of multi-factor analysis also show obvious diversity and complexity due to different research objects,methods and measuring indexes. Therefore,different models for the prediction of particle concentration are needed for the factors such as area,time and meteorological conditions always change.
2.Clinical analysis of QT interval dispersion in predicting susceptibility to ventricular tachycardia in patients with coronary heart disease
Yong JI ; Biao FAN ; Weiqun WANG
Chinese Journal of Practical Internal Medicine 2002;0(08):-
0 05) for inducible VT; Utility of QTD≥70ms combined with positive VLP had a more satisfied outcome than using either of these abnormalities in predicting inducible VT. Conclusion QTD is an easily measurable electrocardiographic index for predicting coronary heart disease.
3.Improvement of Model Establishment of Abdominal Heterotopic Heart Transplantation in Rats
Fan YANG ; Weizhong WANG ; Gang ji
Chinese Journal of Rehabilitation Theory and Practice 2007;13(10):926-927
Objective To establish the model of abdominal heterotopic heart transplantation and grope steady operation methods.Methods The heart transplantation was performed in the control group(group A) and experiment group(group B) with 30 rats in each group.Another 30 animals not performed the operation were as the blank group(group C).During the procurement of the donor heart saline solution containing heparitin was injected into the inferior vena cava of liver.At the same time abdominal aorta was transected.Then heart was perfused until it stopped.The activity of superoxide dismutase(SOD) and content of malondialdehyde(MDA) in blood was measured after transplantation.Results The total perfusion time of the graft was shortened within 2 min and hot ischemia time was shortened within 25 s in the group B.The activity of SOD and content of MDA between two groups was significantly different(P<0.05).Conclusion The perfusing method improved with new technique is quicker and more effective than the traditional one and results in the successful rate improvement.
4.Determination of Calcium Disodium Edetate in Fosaprepitant Dimeglumine for Injection by HPLC
Hongying JI ; Yan LIU ; Fan WANG
China Pharmacist 2015;(5):711-713
Objective:To establish an HPLC method for the determination of calcium disodium edetate in fosaprepitant dimeglu-mine for injection. Methods:The chromatographic column was Agilent Zorbax Eclipse XDB C18(250 mm ×4.6 mm,5μm). The mo-bile phase consisted of 0. 2% tetrabutylammonium hydroxide(adjusting pH to 4. 0 with phosphoric acid)-acetonitrile(85∶15). The flow rate was 1. 0 ml·min-1 . The detection wavelength was 254 nm. The chromatographic column temperature was 35℃. The injection volume was 20μl. Results:The calibration curve was linear within the range of 26. 06-104. 24μg·ml-1(r=0. 999 8) for calcium di-sodium edetate. The average recovery was 99. 51% (RSD=0. 25%, n=9). Conclusion: The method is simple, rapid, accurate, specific and reproducible, and can be used in the determination of calcium disodium edetate in fosaprepitant dimeglumine for injection.
5.Expression of NF-κB gene and its significance in mouse hepatocellular carcinoma cell lines with differently lymphatic metastasis potentials
Xuening JI ; Xuejun FAN ; Mei LI ; Shen Lü ; Ruoyu WANG
Chinese Journal of Clinical and Experimental Pathology 2009;(6):624-627
Purpose To study NF-κB gene expression level in mouse hepatocellular carcinoma cell lines with differently lymphatic metastasis potentials and to discuss its roles in lymphatic metastasis.Methods Using real-time quantitative PCR, NF-κB gene expression level was detected in mouse hepatocellular carcinoma cell lines, including Hca-P with low lymphatic metastasis potential and Hca-F with high lymphatic metastasis potential.Results NF-κB mRNA expression in Hca-P and Hca-F cell lines were (1.41±0.48)×10~(-3),and (2.95±0.22)×10~(-3) (P<0.01),respectively.NF-κB mRNA expression levels were increased with metastasis potential.Conclusion NF-κB gene may play an important role in lymphatic metastasis of hepatocellular carcinoma.
6.Application of different priming dose of muscle relaxant in endotracheal intubation and general anesthesia
Zhonghua JI ; Ruidong QIAO ; Hao WANG ; Xihong FAN
Journal of Chinese Physician 2012;14(2):185-187
ObjectiveTo study the effects of different priming dose of muscle relaxant at the onset and endotracheal intubation conditions.Methods120 ASA Ⅰ~Ⅱ grade patients were randomly divided into 6 groups (n=6),vecuronium group (V 1,V2,V3) and cis-atrscurium group (C1,C2,C3).All patients were induced with propofol plasma (TCI)3 μg/ml,fentanil3 μg/kg.The V1 and C1 group were not given priming dose,and the V2,V3,C2,C3 groups were given priming dose of 10 μg/kg,20 μg/kg vecuronium and 15 μg/kg,30 μg/kg cis-atracurium.Intubating conditions were evaluated,and the onset time was monitored with train-of-four (TOF) technique.ResultsIntubating conditions were excellent in all patients.The onset time of priming groups of the four different doses was significantly shorter than that of the nonpriming group [(80.5±7.2) vs (146±10.7);(79.8±6.5) vs (146±10.7);(138.5±7.2) vs (218±10.7) ; (127.1±6.5) vs (218±10.7),P < 0.05 ].ConclusionsThe taking-effect time of priming dose of muscle relaxant was significantly shorter than that of the nonpriming dose group.Increasing the priming dose not decrease onset time more than the smaller dose.
7.Research progress in strategy of lateral femoral offset reconstruction in total hip arthroplasty.
Qiu-ping FAN ; Bo WANG ; Wei-ping JI
China Journal of Orthopaedics and Traumatology 2016;29(2):192-196
As an important indicator of total hip arthroplasty (THA) the rate and degree of offset reconstruction play an important role in improving the prognosis and life quality of patients. The reconstruction of femoral offset is closely related to reserved length of calcar femorale, the head and neck length of prosthesis, angle degree of neck shaft and whether lower limb is isometric. Reconstruction strategy includes making a meticulous and standard measurement before the surgery, predicting the reserved length of calcar femorale, selecting a prosthesis with approximate anatomical neck-shaft angle and reconstructing offset by adjusting the head and neck length of the prosthetic during the operation. The aim of this article was to introduce the research progress and influence of offset on hip function, prosthetic wear and postoperative complications such as pain, limp and unequal leg length, and to discuss the reconstruction strategy.
Arthroplasty, Replacement, Hip
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adverse effects
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methods
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Femur
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surgery
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Humans
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Reconstructive Surgical Procedures
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adverse effects
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methods
8.Influence of Zidian Granule on the Peripheral Blood Platelet in Mouse Model of Idiopathic Thrombocytopenic Purpura
Ying FAN ; Ji MA ; Shuchun TAO ; Jiahui WANG ; Ying REN
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(03):-
Objective To investigate the changes of the peripheral blood platelet counting and function the mouse model of idiopathic thrombocytopenic purpura (ITP) and to observe the effect of Zidian Granule (ZG). Methods The peripheral platelet counting was conducted with the automatic hemocyte analyzer; CD41 andCD61 level was measured with flow cytometry. Results The amount of the peripheral blood platelet in ITP model mouse was decreased after injection of antiplatelet serum (APS) and CD41 and CD61 were also decreased.(P
9.MRI findings of brain damage due to neonatal hypoglycemia
Lu WANG ; Guoguang FAN ; Xu JI ; Baohai SUN ; Qiyong GUO
Chinese Journal of Radiology 2009;43(1):42-45
Objective To report the MRI findings of brain damage obsenrved in neonatal patients who suffered from isolated hypoglycemia and to explore the value of diffusion-weighted imaging(DWI) inearly detection of neonatal hypoglycemic brain iniun,. Methods Twelve neonates with isolated hypoglycemia(10 of the 12 were diagnosed to suffer from hypoglycemic encephalopathy)were enrolled in this study.They were first scanned at age from 3 days to 10 days with Tl WI,T,WI and DWI(b is 0 s/mm2,1000 s/mm2),and 4 of them were then scanned from 7 days to 10 days following the initial scan.All acquired MR images were retrospectively analysed.Results First series of DWl images showed distinct hyperintense signal in 11 cases in several areas including bi lateral occipital cortex(2 cases),right occipital cortex(1 case),left occipital cortex and subcortical white matter(1 case),biIateral occipital cortex and flubcortical white matter(2 cases),bilateral parieto-occipital cortex(2 cases),bilateral parieto-occipital cortex and subcortical white matter(2 cases),the splenium of corpus catlosum(4 cases),bilateral corona radiata(2 cases),left eaudate nucleus and globus pallidus(1 case),bilateral thalamus(1 case),bilaterally posterior limb of internal capsule(1 ease).In the initial T1 WI and T2,WI images,there were subtle hypointensity in the damaged cortical areas(3 cases),hyperintensity in the bilaterally affected occipital cortex(1 case)on T1 weighted images,and hyperintensity in the affected cortex and subcortieal white matter with poor differentiation on T2 weighted images.The followed-up MRI of 4 cases showed regional encephalomalaeia in the affected occipital lobes(4 cases),slightly hyperintensity on T2 weighted images in the damaged occipital cortex(2 cases),extensive demyelination(1 case).disappearance of hyperintensity of the splenium of corpus callosum(1 case),and persistent hyperintensity in the splenium of corpus callosum (1 case)on T2 weighted images.Conclusion The findings suggest that posterior parieto-occipital regions are most frequently injured in neonatal period due to severe hypoglycemia.DWI is a useful technique in the early detection and evaluation of hypoglycemic brain injury of neonates.
10.Method to Increase Cleaniness of Blind Zone of Complicated Medical Instruments
Suzhen WANG ; Zhengxiang LIU ; Fan YANG ; Yuling JI
Chinese Journal of Nosocomiology 2006;0(03):-
OBJECTIVE To explore an effective cleaning method to improve the washing quality of contaminated complicated medical instruments.METHODS The used puncture needles were washed by three methods(ultrasonic wave only,ultrasonic wave + polyenzyme detergent,ultrasonic wave + spray washing with special washing-rack designed by ourselves,while artificial washing group as control group,3 pieces per group).After washing,the samples were further assayed with HemoCheck-s swab to compare the washing effect.RESULTS The color of cotton swabs was turned blue or light blue.CONCLUSIONS Our results have demonstrated that ultrasonic cleaning plus spray washing with special washing-rack can improve the cleaning quality.