1.Advance in Research on Effect of Sports Activities on Intellectuality of Mental Retardation Children (review)
Weihua CHAO ; Li LI ; Hong JI
Chinese Journal of Rehabilitation Theory and Practice 2007;13(2):156-158
In the special education field, sports are benefit to body and mental health, and also can improve abilities of taking care by self and adapting society. In this article, the authors summarized both domestic and foreign researches on the problem of intellectual influence of sports activities on mental retardation children, and put forward the future research direction and prospect.
3.Influence of therapeutic exercise on blood homocysteine levels in patients with coronary artery disease
Ji LUO ; Chao LI ; Yan LI ; Dao-Qing WANG ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(05):-
0.05).Meanwhile,the cardiac function and the quality of life of the rehabilitation exercise group was improved to a significantly larger extend than those of the control group (P
4.Analysis of Acid-Base Disturbance Caused by Severe Pneumonia in Newbern Infants
chao, QIN ; ming-li, JI ; hong-yun, LI
Journal of Applied Clinical Pediatrics 2003;0(10):-
Objective To analyze the type of acid-base disturbance caused by severe pneumonia in newborn infants .Methods Venous blood of neonate with severe pneumonia(SP group) were collected to detect serum electrolyte and blood gas analysis 12 hours before and after oxygen therapy .The results of serum electrolyte and blood gas were compared 12 hours before and after oxygen therapy ,and the results of acid-base disturbance between SP group and control groups were compared.Results There were mostly metabolic acidosis incorporated respiratory acidosis in all neonate in SP group,which were with increased anion gap (AG) and obviously higher than that of control group(t=1.27 P
5.Oxidative Stress and Expression of Bax and Bcl-2 in Rat Corpus Striatum Induced by 6-Hydroxydopamine
Tao WANG ; Chao JI ; Qing LI ; Qingjun ZHANG ; Pingping ZUO
Chinese Journal of Rehabilitation Theory and Practice 2009;15(5):431-433
Objective To study the oxidative stress and apoptosis relative protein expression in rat striatum during the pathogenesis of Parkinson's disease (PD) induced by 6-hydroxydopamine (6-OHDA). Methods 6-OHDA was stereotacticly injected into the right striatum of the rats at two sites to produce PD models. Activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), contents of reduced glutathione (GSH) and malondialdehyde (MDA) in the injured and normal striatum were measured using assay kits; and levels of Bax and Bcl-2 were detected by Western blotting in injured striatum. Results In 10 successful PD rats, compared with either the sham group or the normal group, activities of SOD and GSH-Px and contents of GSH in the right striatum significantly decreased while contents of MDA increased obviously (P<0.05); And levels of Bax significantly increased while expression of Bcl-2 obviously decreased. Conclusion Oxidative stress plays a key role in the pathogenesis of PD. Furthermore, Bax and Bcl-2 were involved in the regulation of apoptosis under oxidative stress induced by 6-OHDA.
6.Research progress of iron metabolism and its mechanism in the treatment of heart failure
Xiao-li WEI ; Ji-chao ZHOU ; Xiao-wei ZHANG
Acta Pharmaceutica Sinica 2022;57(6):1584-1592
The pathogenesis of heart failure is a complex progression and associated with abnormal regulation of many signaling pathways. As a cofactor of hemoglobin, myoglobin, oxidative respiratory chain, DNA synthase and other important proteins, iron plays an indispensable role in myocardial energy metabolism. Recently, a large number of studies have shown that heart failure is related to the disorder of iron metabolism. Both iron deficiency and iron overload can lead to the development of a variety of cardiomyopathy, and even progress to heart failure. Iron metabolism could be a key target for the diagnosis, prevention and treatment of heart failure. Here, we review the basic process of iron metabolism and its mechanism in heart failure, expecting to provide new clues and evidence for the treatment of heart failure.
8.Investigation on sensitivity of mites of acaro-asthma patients in different jobs.
Ji HE ; Hui-yong WANG ; Jia-jia JIANG ; Chao-pin LI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2005;23(6):447-448
Adult
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Animals
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Asthma
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epidemiology
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etiology
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Female
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Humans
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Immunoglobulin E
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blood
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Male
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Occupational Diseases
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epidemiology
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etiology
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Pyroglyphidae
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Skin Tests
9.Surgical repair and reconstruction of male external genitals.
Zhong WANG ; Hai-jun YAO ; Da-chao ZHENG ; Wen-ji LI
National Journal of Andrology 2015;21(7):579-586
One of the challenges in andrology nowadays is the diagnosis and treatment of external genital abnormalities and defects along with the consequent voiding, sexual, and reproductive dysfunctions, for which no guidelines are yet available. Hitherto, surgical repair and reconstruction are efficient for these diseases. The key to these operations is to individualize surgical strategies according to the specific local lesion and dysfunction, usually involving flap and graft techniques. This article presents our experience in the surgical treatment of penile and scrotal abnormalities and defects with urological and andrological techniques and microsurgical strategies, focusing on the external repair and functional reconstruction. Satisfactory treatment outcomes pivot on a precise evaluation of the disease, a rational design of surgical procedures, and an earnest communication with the patient. Some cases are rather complicated and challenging, usually with complications, and therefore deserve further researches for more effective treatment strategies in clinical practice.
Andrology
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Genitalia, Male
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abnormalities
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surgery
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Humans
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Male
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Penis
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abnormalities
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surgery
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Reconstructive Surgical Procedures
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methods
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Scrotum
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abnormalities
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surgery
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Surgical Flaps
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Treatment Outcome
10.Isolated type C interrupted aortic arch in adult: extra-anatomic repair using circulatory arrest.
Xing-rong LIU ; Qi MIAO ; Guo-tao MA ; Chao-ji ZHANG ; Li-hua CAO
Chinese Medical Sciences Journal 2013;28(4):239-241
Adult
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Aorta, Thoracic
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abnormalities
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surgery
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Heart Arrest, Induced
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Humans
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Male