The solitary type of Koratoacanthoma is a common, rapidly growing, benign tumor with a natural history of spontaneous involution which was first described by Hutchinson in 1889. It was well known that this Keratoacanthoma is close resemblence to squamous cell carcinoma clinicallt & histopathology. The etiology of Kertoacanthoma is ucertain but it have been associated with many exogenous factors, including sun exposure, occupational exposure to heat and trauma, and tar and with autoimmune etiology and viral infection. We experienced 2 cases of soitary type of Keratoacantoma with typical clinical and histopathologic findings which presented on the pubic area and forehead but had no predisposing factors of Keratoacanthoma. The one was 66-year-old woman who had been a history of proritic, rapidly growing tumor on Mons Pubis since about 6 months ago. The another one was 40 year-old male who had been a history of asymromatic, growing tomor on forehead since about 3 months ago. In the H-E stained sections, there were horn filled invagination, dyskeratotic cell, horn pearl in the epidermis and an inflammatory infiltration in dermis. Diagnosis was cinfirmedby the clinical and histopatholigical pictures. The former was treated by electrocautery after simple excision and the latter by curretage and electrodesiccation.
Adult ; Aged ; Animals ; Carcinoma, Squamous Cell ; Causality ; Dermis ; Diagnosis ; Electrocoagulation ; Epidermis ; Female ; Forehead ; Horns ; Hot Temperature ; Humans ; Keratoacanthoma* ; Male ; Natural History ; Occupational Exposure ; Solar System

Malignant melanoma is a tumor arising within the melanocyte system of the skin, eyes and juxtacutaneous mucous membrane. Tbrough the lymphatic channel developed early metastasis and regional lymphade- nopzthy developed. Malignant melanoma may arise on apparently normal skin, in a junction nevua, rareh in a compound nevus and extremeIy rarely in an intradermaI nevus and 20% of total incidence of malignant melanoma are preceded by a nevocellular nevus. A 41 year-old male patient who had multiple, pea to walnut sized, black colored. nodules developing on entire body visited our Dermto. dept. About one year ago, solitary black colored nodule arose from preexisting pigmented nevus which had been from 20 yrs ago on Rt. ant. axillary area and then nodule remcved by wide exeision and regional lymphadenectomy at a Hosp. 2 months after surgical operation, multiple pea to walnut sized, black colored nodules has developed on entire body. There was no lymphadenopathy on entire body. In H-E & Fontana-Masson stain, numerous bizzarre large cells with hyperchromatic variable sized melanin pigments are seen in the dermis and subcutaneous tissues Mitotic figutes are present. Diagnosis was confirmed by the clinical and histological feature. The patient was treated with BCG waccination(4*10^6-8*10^6 live organisms weekly) by altemately intralesional inj, on the lesion and subcuraneous inj. on both shoulder during 6wks and has been in follow-up.
Adult ; Ants ; Dermis ; Diagnosis ; Follow-Up Studies ; Humans ; Incidence ; Juglans ; Lymph Node Excision ; Lymphatic Diseases ; Male ; Melanins ; Melanocytes ; Melanoma* ; Mucous Membrane ; Mycobacterium bovis ; Neoplasm Metastasis ; Nevus ; Nevus, Pigmented* ; Peas ; Shoulder ; Skin ; Subcutaneous Tissue

Tuberculosis of the skin may present clinically as plaques, ulcers, verrucous, lesions, nodules, tumors, vegetatives reactions, and cicartricial infiltration. The reaction of the host to the presence of Mycobacterium tuberculosis also varies with the extent and the degree of invasion, the virulence of the bacilli, and nonspecific factors such as age and generaI state of health. The incidence of cutaneous tuberculosis has tendency to decline in the world because of thc availability of effective antiTB drugs, elimination of infected milk herbs, and an elevation of living standards, but in Korea, cutaneous tuberculosis remained to be a significant medical problem. We experienced 21 year-old male who had a case of 3 clinical types including Lupus vulgaris, Scrofuloderma, Papulonecrotic tuberculid. Diagnosis of 3 clinical types vere established by clinical history and signs, histo pathology, tuberculin test and effective of treatment vith INH, streptomycin and literature were reviewed.
Diagnosis ; Dronabinol ; Humans ; Incidence ; Korea ; Lupus Vulgaris ; Male ; Milk ; Mycobacterium tuberculosis ; Pathology ; Skin ; Socioeconomic Factors ; Streptomycin ; Tuberculin Test ; Tuberculosis ; Tuberculosis, Cutaneous* ; Ulcer ; Virulence ; Young Adult

Neuroblastoma stage IV-S patients have frequent spontaneous remission and high survival rate. Many investigators have recommended minimal or no therapeutic intervention ; however, some patient do experience progressive disease and ultimately die of neuroblastoma. We experienced a case of stage IVS neuroblastoma with N-myc amplification and coagulopathy. This patient has treated with combination chemotherapy and radiation therapy, then remained disease free for 1 year on the follow up till March, 1997.
Drug Therapy, Combination ; Follow-Up Studies ; Humans ; Neuroblastoma* ; Remission, Spontaneous ; Research Personnel ; Survival Rate

No Abstract Available.

Central retinal vein occlusion(CRVO) is a common retinal vascular disorder with potentially blinding complications. Author evaluated the 21 cases of central vein occlusion in aspects of age, laterality, change of visual acuity, axial length, associated diseases and complications. The results were as follows; 1. The patients were comprised of 8 males and 13 females and the average age was 49.2 +/- 12.5 years. 2. The left eye was affected more than the right eye. 3. The initial visual acuity was below 0.1 in 76.2%. 4. The mean axial length of the aftected eyes(23.03 +/- 0.69mm) was shorter than that of their control group(23.53 +/- 0.69mm) (P=0.01). 5. The most common associated disease was hypertension (33.3%) and the next was diabetes mellitus (9.5%) and arteriosclerosis (9.5%). 6. The most common complication was cystoid macular edema (42.9%). Retinal and disc neovascularization was occmed in 19.4%.
Female ; Male ; Humans

An obturator hernia is an extremely rare rupture that protrudes through the canal that transmits the obturator vessels. We performed computed tomography of the abdomen and pelvis on two elderly debilitated women patients with small bowel obstructions to make a correct diagnosis. We report these with a brief review of the literature.
Abdomen ; Aged ; Diagnosis ; Female ; Hernia, Obturator* ; Humans ; Pelvis ; Rupture

The Ministry of Health and Welfare introduced a new reimbursement system called the Eligibility Management System in Medical Aid in July 2007. The operation of this system is interlocked with patient care programs of medical institutions. The new system was expected to realize effective management of the eligibility of beneficiaries by interactive communications between medical institutions and the National Health Insurance Corporation (NHIC) and thereby improve financial stabilization of the reimbursement system and optimize healthcare practices by preventing moral hazards in the relationship between beneficiaries and medical institutions. For the effective operation of this system, however, several drawbacks need to be resolved; firstly, one can currently use the system only through the internet, secondly, there is a legal issue that medical institutions are the subject of the management of eligibility, and lastly, healthcare information needs to be transferred to NHIC in a real-time manner. Particularly the last one needs a special attention because it can raise critical concerns of potential violation of human rights of patients and unnecessary regulations of medical practices.
Delivery of Health Care ; Human Rights ; Humans ; Internet ; National Health Programs ; Patient Care ; Social Control, Formal

No abstract available.
Chitosan*

No abstract available.
Korea* ; Tuberous Sclerosis*