Phototherapy is the most common and effective method to intervene and treat neonatal hyperbilirubinemia in clinic.The application of phototherapy varies from gestational age,birth weight,age and many other factors.Beside the traditional phototherapy instruments,more advanced high-intensive phototherapy instruments are applied to phototherapy.With the increasing application of phototherapy,many problems have showed up.This paper reviews based on the research of the indication,clinical application and adverse reactions on phototherapy.

OBJECTIVE:To investigate the effect of NGF on release of NO from peritoneal macrophages in mice METHODS:The content of NO in macrophages was detected with Griess agent RESULTS:NGF,in concentration of 0 73mg～5 83mg free amino acid per ml,could significantly inhibit release of NO from peritoneal macrophages in mice CONCLUSION:Inhibiting NO release may be one of the mechanism of NGF in protecting neurons

Objective:To observe the anesthetic effects of SumianxinⅡ combined with diazepam on the Beagle dogs in experimental periodontal surgery to Provide the reference. Methods:Healthy adult male Beagle dogs were anesthetized with SumianxinⅡat the doses of 0.05、0.1、0.15 ml/kg in the combination group and diazepam(0.1 ml) by hip intramuscular injection simultaniously. Added injection dosage was half of the first dosage. Healthy adult Beagle dogs in the contral group were only anesthetized with SumianxinⅡ at the doses of 0.05、0.1、0.15 ml/kg by hip intramuscular injection. The time of adding anesthetic was not sure in surgery. Anesthesia induction period,initial duration of anesthesia,and adverse reactions after anesthesia were compared between the two groups. Results: The combined treatment group induction dose respectively (11.00?1.41) min,(9.00?0.82) min,(12.75?0.50) min,For the first time maintaining anesthesia(29.75?6.62) min,(46.00?5.29) min,(45.25?6.02) min,Intraoperative additional one times longer cansustain anesthesia for(38.75?3.50) min,(45.25?4.03) min,(37.25?2.75) min. Pure Sumianxin Ⅱ new standards of sleep narcotic induction respectively respectively was (15.75?2.50) min,(14.25?2.99) min,(14.50?2.08) min,For the first time maintaining anesthesia was (20.75?5.19) min,(20.5?3.42) min,(22.25?5.19) min,the time of adding anesthetic was not sure in surgery. 2 Dogs died in SumianxinⅡ group. United drug group simple Sumianxin Ⅱ induction period in each group by t test,Sumianxin Ⅱat the doses of 0.1 ml/kg supplemented with 0.3 ml dose stability (P

The feasibility of screening for antibody to HIV by pooling 10 serum specimens was demonstrated in this experiment. The test was conducted using the reagent developed by Organon Teknika corporation (U. S. A) for testing for antibody to HIV by ELISA. The determination was made by changing only the ratio between the serum specimen volume and the serum specimen diluent volme, with their total volume being constant. When the serum specimen volume was increased from 5to 59?l as a result of pooling 10 serum specimens, while the serum specimen diluent volume was correspondingly decreased, the optical density of the pooled serum specimens was somewhat raised, but it was always below cutoff value, indicating that the specificity of test did not be subjected to any influence. In addition, when one serum specimen estabished as being positive intesting for antibody to HIV, and nine serum specimens from normal donors were pooled, the serum specimen containing the antibody to HIV had exactly been shown through multiple paired tests, indicating that the serumpooling method did not have any influence on the test sensitivity and could reach the level of original method. The serum-pooling method could be easy to spread because of its many advantages, such as saving the expenditure by 10 times, saving the manpower and material resource, and saving the working hours. (Original article on page 5)

Purpose　The aim is to investigate the effects of thymopeptide on LPS-induced release of nitric oxide (NO) from mouse peritoneal microphase in vitro.Methods　NO was detected by Griess reagent.Results　Thymopeptide 83.3～333.3 μg/ml reduced NO synthesis and secretion from mouse peritoneal microphase in vitro significantly.Conclusion　The effects of thymopeptide on LPS-induced release of NO from mouse peritoneal microphase may be one of mechanisms of its pharmacological effect.

Child ; Early Diagnosis ; Evidence-Based Medicine ; Glomerulonephritis ; diagnosis ; therapy ; Glomerulonephritis, Membranous ; diagnosis ; therapy ; Humans ; Kidney Diseases ; diagnosis ; therapy ; Kidney Glomerulus ; pathology ; Nephrosis, Lipoid ; diagnosis ; therapy ; Renal Replacement Therapy

Child ; Glomerulonephritis ; classification ; diagnosis ; therapy ; Humans

Objective To investigate the value of BISAP scoring system in predicting the severity of acute pancreatitis.Methods Medline,EMBASE,Science Direct,Springer link,CBM,Cnki,Wan fang and VIP database were retrieved by computer between January 2000 and March 2013,and articles of BISAP score system in predicting the acute pancreatitis were collected according to strict inclusion criteria.Quality assessment was made by QUADAS scale.Meta-Disc1.4 software was used to analyze the heterogeneity of included articles and perform quantitative synthesis,as well as calculate the pooled sensitivity and specificity,positive likelihood ratio,negative likelihood ratio,and draw the ROC curve,and the results were presented with 95％ CI.Results A total of 11 articles were included,and there were 7 Chinese articles and 4 English articles.According to QUADAS scale,there were 4 articles of A grade,5 articles of B grade,2 articles of C grade.There were 6 studies using 2 as BISAP cut-off value,and 9 articles using 3 as cut-off value,while 4 studies using 2 cut-off values.Pooled analysis showed diagnostic odds ratio of 8.03 (95 ％ CI 5.66-11.38) when cut-off value was 2,and diagnostic odds ratio of 7.49 (95％ CI 5.35-10.49) when cut-off value was 3.There were moderate heterogeneity in both groups (I2 =63.3 ％,P =0.018; I2 =56.1％,P =0.019).When BISAP cut-off value was 2,the pooled analysis of sensitivity,specificity,positive likelihood ratio,negative likelihood ratio and area under curve (AUC) were 59％ (95％ CI56％-63％),82％ (95％ CI 80％-83％),3.50 (95％ CI2.96-4.14),0.45 (95％ CI0.36-0.56) and0.82; and when BISAP cut-off value was 3,the corresponding values were 44％ (95％ CI41％-47％),90％ (95％ CI 89％-91％),4.59 (95％ CI 3.31-6.37),0.64 (95％ CI 0.61-0.68) and 0.64.The former had a high sensitivity,low specificity and large AUC,while the latter had a low sensitivity,high specificity and small AUC.Conclusions The best cut-off value of BISAP in predicting SAP is 2.When cut-off value is 2,the misdiagnosis rate is low,and the false positive rate is in the acceptable range,which is suitable for clinical application.

Humans ; Proteinuria ; diagnosis ; therapy

Objective To evaluate the value of MR in the diagnosis of glomus jugulare tumors.Methods 15 cases (8 in the right and 7 in the left-side) of glomus jugulare tumors were retrospectively analysed, with the emphasis on the locations, MR signal intensities andthe invading appearances to the surrounding structures of tumors. Results The tumors demonstrated as oval or irregular shape. Thesurrounding bones around the jugular fossa were destroyed in 12 masses. The signal intensity of the tumors was heterogeneous and with marked “salt and pepper”appearance in 12 masses(12/15) on plain MR imaging. The masses(13/13)were all markedly enhanced after the injection of Gd-DTPA, in which 10 of them presented with “salt and pepper”appearance. MR angiography was performed in 9 cases, theinternal carotid artery and the internal jugular vein were all displaced and/or encompassed.Conclusion Glomus jugulare tumor can becorrectly diagnosed according to the combination of MR imaging features with the typical localization,“salt and pepper” appearance and bone erosion in the skull base.