This study aimed to assess the sustainability of antibacterial agents mixed with experimental fluoride varnish (EFV) against S. mutans. Five antibacterial agents [Xanthorrhizol (XAN), Bakuchiol (BAK), Bavachalcone (BCC), Isobavachromene (IBC), and Bavachromene (BCM)] were used and incorporated into the EFV to make the final concentration of 10 mM. Then, 5 μL of antibacterial agents mixed with EFV were applied on polyethylene terephthalate film disc (5 mm diameter). The positive and vehicle control were ampicillin and DMSO mixed with EFV, respectively. Each group was stored in distilled water in a 37℃ shaking water bath at 80 rpm for 0 hour, 4 hours, 1 day, 2 days, 3 days, 5 days, 10 days, 20 days and 30 days. The sustainability of the antibacterial activities was evaluated with the inhibition zone by the agar diffusion test. The antibacterial activities of all antibacterial agents were sustained for 30 days. Among them, BCC showed relatively higher antibacterial activities up to 30 days compared to other groups. This study suggests that antibacterial agents including BCC can be used with fluoride varnish to have sustained antibacterial activities.

This study was conducted to compare the flexural properties and biocompatibility of experimental 3D printing resins with commercial 3D-printing resins and conventional denture base resin. Auto polymerized pour-type denture base resin (RESS LT; Retec, Germany) was used as a control group. A commercial 3D printing denture base resin, NextDent (Base, Vertex Dental, Soesterberg, Netherlands) and two 3D printing resins, White prototyping resin (PR57-W, Autodesk, USA) and Clear prototyping resin (PR48, Autodes, usa) were compared. Experimental 3D printing resins (E1, E2, E3) were made with different ratios of dimethacrylates. DLP 3D printer (VIDA, Envisiontec) was used for 3D printing. The specimens (64×10×3.3 mm) were made based on the protocol of ISO 20795-1. The flexural strength and flexural modulus were measured by a universal testing machine (Z020, Zwick, Germany) at a crosshead speed of 5 mm/min. MTT test was performed to evaluate the cell viability. The flexural strength and flexural modulus of E2 were significantly higher than those of other groups (p<0.05). Biocompatibility of all experimental 3D printing resins were not significantly different from negative group (p>0.05). E2 is considered to be a promising material as a denture base resin for 3D printing.

BACKGROUND/OBJECTIVES: Sleep duration and diet quality are reportedly associated with the risk of diabetes. This study aimed to examine the risk of diabetes according to sleep duration and diet quality in middle-aged Koreans. SUBJECTS/METHODS: Using the Korea National Health and Nutrition Examination Survey 2019–2020, raw data from 2,934 participants aged 40–64 yrs (1,090 men and 1,844 women) who were not diagnosed with type 2 diabetes were analyzed. With a sleep duration of 7–7.9 h per night as the referent category, diet quality was assessed using the Korean Healthy Eating Index (KHEI), which comprises adequacy, moderation, and energy balance. RESULTS: The study results showed that individuals with a short sleep duration had significantly higher blood glucose (P = 0.034) and HbA1c levels (P < 0.001) than those had by individuals with a sleep duration of 7–7.9 h. Within the group with a sleep duration of 7–7.9 h, the lowest quintile of the KHEI score had a significantly higher risk of prediabetes than that had by the highest quintile of the KHEI score (Model 1: odds ratio [OR], 1.775; 95% confidence interval [CI], 1.072–2.939; P < 0.05 and Model 2: OR, 1.731; 95% CI, 1.040–2.882; P < 0.05). CONCLUSION Our findings suggest that achieving the sleep duration of 7–7.9 h and eating good diet are associated with the lowest risk of prediabetes. We recommend that the results of this study be used to educate adults aged 40–64 yrs on diet and lifestyle habits to prevent diabetes.

BACKGROUND/OBJECTIVES: Sleep duration and diet quality are reportedly associated with the risk of diabetes. This study aimed to examine the risk of diabetes according to sleep duration and diet quality in middle-aged Koreans. SUBJECTS/METHODS: Using the Korea National Health and Nutrition Examination Survey 2019–2020, raw data from 2,934 participants aged 40–64 yrs (1,090 men and 1,844 women) who were not diagnosed with type 2 diabetes were analyzed. With a sleep duration of 7–7.9 h per night as the referent category, diet quality was assessed using the Korean Healthy Eating Index (KHEI), which comprises adequacy, moderation, and energy balance. RESULTS: The study results showed that individuals with a short sleep duration had significantly higher blood glucose (P = 0.034) and HbA1c levels (P < 0.001) than those had by individuals with a sleep duration of 7–7.9 h. Within the group with a sleep duration of 7–7.9 h, the lowest quintile of the KHEI score had a significantly higher risk of prediabetes than that had by the highest quintile of the KHEI score (Model 1: odds ratio [OR], 1.775; 95% confidence interval [CI], 1.072–2.939; P < 0.05 and Model 2: OR, 1.731; 95% CI, 1.040–2.882; P < 0.05). CONCLUSION Our findings suggest that achieving the sleep duration of 7–7.9 h and eating good diet are associated with the lowest risk of prediabetes. We recommend that the results of this study be used to educate adults aged 40–64 yrs on diet and lifestyle habits to prevent diabetes.

BACKGROUND/OBJECTIVES: Sleep duration and diet quality are reportedly associated with the risk of diabetes. This study aimed to examine the risk of diabetes according to sleep duration and diet quality in middle-aged Koreans. SUBJECTS/METHODS: Using the Korea National Health and Nutrition Examination Survey 2019–2020, raw data from 2,934 participants aged 40–64 yrs (1,090 men and 1,844 women) who were not diagnosed with type 2 diabetes were analyzed. With a sleep duration of 7–7.9 h per night as the referent category, diet quality was assessed using the Korean Healthy Eating Index (KHEI), which comprises adequacy, moderation, and energy balance. RESULTS: The study results showed that individuals with a short sleep duration had significantly higher blood glucose (P = 0.034) and HbA1c levels (P < 0.001) than those had by individuals with a sleep duration of 7–7.9 h. Within the group with a sleep duration of 7–7.9 h, the lowest quintile of the KHEI score had a significantly higher risk of prediabetes than that had by the highest quintile of the KHEI score (Model 1: odds ratio [OR], 1.775; 95% confidence interval [CI], 1.072–2.939; P < 0.05 and Model 2: OR, 1.731; 95% CI, 1.040–2.882; P < 0.05). CONCLUSION Our findings suggest that achieving the sleep duration of 7–7.9 h and eating good diet are associated with the lowest risk of prediabetes. We recommend that the results of this study be used to educate adults aged 40–64 yrs on diet and lifestyle habits to prevent diabetes.

BACKGROUND/OBJECTIVES: Sleep duration and diet quality are reportedly associated with the risk of diabetes. This study aimed to examine the risk of diabetes according to sleep duration and diet quality in middle-aged Koreans. SUBJECTS/METHODS: Using the Korea National Health and Nutrition Examination Survey 2019–2020, raw data from 2,934 participants aged 40–64 yrs (1,090 men and 1,844 women) who were not diagnosed with type 2 diabetes were analyzed. With a sleep duration of 7–7.9 h per night as the referent category, diet quality was assessed using the Korean Healthy Eating Index (KHEI), which comprises adequacy, moderation, and energy balance. RESULTS: The study results showed that individuals with a short sleep duration had significantly higher blood glucose (P = 0.034) and HbA1c levels (P < 0.001) than those had by individuals with a sleep duration of 7–7.9 h. Within the group with a sleep duration of 7–7.9 h, the lowest quintile of the KHEI score had a significantly higher risk of prediabetes than that had by the highest quintile of the KHEI score (Model 1: odds ratio [OR], 1.775; 95% confidence interval [CI], 1.072–2.939; P < 0.05 and Model 2: OR, 1.731; 95% CI, 1.040–2.882; P < 0.05). CONCLUSION Our findings suggest that achieving the sleep duration of 7–7.9 h and eating good diet are associated with the lowest risk of prediabetes. We recommend that the results of this study be used to educate adults aged 40–64 yrs on diet and lifestyle habits to prevent diabetes.

BACKGROUND/OBJECTIVES: Sleep duration and diet quality are reportedly associated with the risk of diabetes. This study aimed to examine the risk of diabetes according to sleep duration and diet quality in middle-aged Koreans. SUBJECTS/METHODS: Using the Korea National Health and Nutrition Examination Survey 2019–2020, raw data from 2,934 participants aged 40–64 yrs (1,090 men and 1,844 women) who were not diagnosed with type 2 diabetes were analyzed. With a sleep duration of 7–7.9 h per night as the referent category, diet quality was assessed using the Korean Healthy Eating Index (KHEI), which comprises adequacy, moderation, and energy balance. RESULTS: The study results showed that individuals with a short sleep duration had significantly higher blood glucose (P = 0.034) and HbA1c levels (P < 0.001) than those had by individuals with a sleep duration of 7–7.9 h. Within the group with a sleep duration of 7–7.9 h, the lowest quintile of the KHEI score had a significantly higher risk of prediabetes than that had by the highest quintile of the KHEI score (Model 1: odds ratio [OR], 1.775; 95% confidence interval [CI], 1.072–2.939; P < 0.05 and Model 2: OR, 1.731; 95% CI, 1.040–2.882; P < 0.05). CONCLUSION Our findings suggest that achieving the sleep duration of 7–7.9 h and eating good diet are associated with the lowest risk of prediabetes. We recommend that the results of this study be used to educate adults aged 40–64 yrs on diet and lifestyle habits to prevent diabetes.

Cataract operation was carried out in 7 glaucomatous eyes with prolonged ocular hypotony after trageculectomy with intraoperative mitomycin C. In all cases, The postoperative intraocular pressure(IOP) rose and the postopeative average IOP was 6.0+/-2.0mmHg higher than their preoperative average IOP. The preexisting bleb was reduced in size eyes that underwent phacoemulsification and posterior chamber intraocular lens(PC-IOL) implantation. But. It was not changed in extracapsular cataract extraction and IOL implantation. In our study, cataract operation in eyes that had lens opacity with prolonged hypotony induced IOP rise and was beneficial to hypotony.
Blister ; Cataract Extraction ; Cataract* ; Mitomycin* ; Ocular Hypotension* ; Phacoemulsification ; Trabeculectomy*

Intravascular lymphomatosis (IL) is a variant of non-Hodgkin's lymphoma with an predilection for the CNS. Most cases are not diagnosed until postmortem. IL is characterized by neoplastic proliferation of lymphoid cells within the lumen of small veins and arteries with minimal involvement of the parenchyma. We experienced a 62-year-old woman who presented with seizure and fever associated with anemia, elevated LDH and beta 2-microglobulin without systemic involvement. This report illustrates the diagnostic challenge of this rare disorder with a grave prognosis. (J Korean Neurol Assoc 19(4):413~416, 2001)
Anemia ; Arteries ; beta 2-Microglobulin ; Central Nervous System* ; Female ; Fever ; Humans ; L-Lactate Dehydrogenase ; Lymphocytes ; Lymphoma, Non-Hodgkin ; Middle Aged ; Prognosis ; Seizures ; Veins

It is often problematic to diagnose T-cell lymphoproliferative disorders of the skin because of the difficulty in establishing clonality in paraffin-embedded tissue. We used polymerase chain reaction single strand conformational polymorphism (PCR-SSCP) and heteroduplex analysis in paraffin embedded tissue to detect clonal rearrangement of T-cell receptor gamma (TCRgamma) gene in 17 T-cell lymphoproliferative disorders and 6 atypical lymphoproliferative diseases. We used polymerase chain reaction to detect TCR beta gene rearrangement in 8 of 17 cases which did not show TCRgamma gene rearrangement. Jurkat cell lines were used as monoclonal controls. DNA was extracted from 5 biopsies of T-cell lymphomas, 10 biopsies of mycosis fungoides, 2 biopsies of lymphomatoid papulosis, and 6 biopsies of atypical lymphoproliferative lesions. We detected monoclonality in 5 of 5 T-cell lymphoma cases, 2 of 2 lymphomatoid papulosis cases, 6 of 10 mycosis fungoides cases, and 2 of 6 atypical lymphoproliferative disease cases. We conclude that nonradioactive PCR-SSCP for TCR gene rearrangement analysis is a useful adjunct to routine histological and immunophenotypic methods in the diagnosis of cutaneous T cell lymphoproliferative disorders in paraffin embedded tissue.
Biopsy ; Diagnosis* ; DNA ; Gene Rearrangement ; Genes, T-Cell Receptor ; Genes, T-Cell Receptor beta ; Heteroduplex Analysis ; Humans ; Jurkat Cells ; Lymphoma, T-Cell ; Lymphomatoid Papulosis ; Lymphoproliferative Disorders ; Mycosis Fungoides ; Paraffin ; Polymerase Chain Reaction ; Receptors, Antigen, T-Cell ; Skin ; T-Lymphocytes