1.Study on the Correlation between hs-CRP and TCM Syndromes of Metabolic Syndrome
Shihan WANG ; Jie WANG ; Ji LI
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(09):-
Objective To discuss the correlation between hs-CRP and patterns of metabolic syndrome in TCM.Method One hundred patients with metabolic syndrome were classified according to patterns of TCM.The correlation between hs-CRP and patterns of metabolic syndrome in TCM was observed.Result hs-CRP of patients group was superior to that of control group (P
3.Therapeutic Observation of Auricular Point Sticking plus Basic Nursing for Constipation of Excessive Syndrome in Acute Stage of Stroke
Jie JI ; Yanwei WANG ; Shaolin REN
Shanghai Journal of Acupuncture and Moxibustion 2016;35(3):276-278
Objective To observe the clinical efficacy of auricular point sticking plus basic nursing for constipation of excessive syndrome in acute stage of stroke.Method Ninety patients with constipation of excessive syndrome in acute stage of stroke were randomized into a treatment group and a control group, 45 cases in each group. The treatment group was intervened by auricular point sticking plus basic nursing, while the control group was by basic nursing alone. The major symptom scores were observed before intervention and after 2-treatment courses, and the clinical efficacies were compared between the two groups.Result Respectively after 1 and 2 treatment courses, there were significant differences in comparing the major symptom scores between the two groups (P<0.05). The total effective rates were respectively 60.0% and 67.5% in the treatment group respectively after 1 and 2 treatment courses, versus 37.5% and 45.0% in the control group, and the differences were statistically significant (P<0.05). Conclusion Auricular point sticking is an effective approach in treating constipation of excessive syndrome in acute stage of stroke.
4.Research on the association among TCM syndrome,t-PA and PAI in serum and the risk stratif ication of UA
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective:To discuss the relation among t-PA,PAI,unstable angina risk strati cation and its TCM syndrome.Methods:Syndrome di erentiation,coronary angiography and risk strati cation for 86 cases of unstable angina pectoris were carried out,and Gensini scoring system was used to assess the results of coronary angiography,blood stasis score was used to assess the degree of blood stasis.Serum blood serum t-PA and PAI levels were detected for statistical analysis.Results:In 86 cases of patients with low-risk,middle-risk and high-risk groups,with the incremental risk strati cation,blood stasis and Gensini score were increased,by comparison among the three groups,the di erences was existed(P
6.Clinical Study:Concurrent Interventional Cisplatin Ieucovorin Fluorouracil Hydroxy Camptothecin Chemotherapy Plus Radiotherapy in Patients with Ⅳ Stage Middle-lower Section Esophageal Cancer
Tongli JI ; Yiqing WANG ; Jie MIN ; Gang LI
Journal of Practical Radiology 2001;0(07):-
Objective To investigate the efficacy of concurrent interventional cisplatin,leucovorin,fluorouracil,hydroxy camptothecin chemotherapy plus radiotherapy in patients with Ⅳ stage middle-lower section esophageal cancer.Methods The subjects were all the patients with Ⅳ stage middle-lower section esophageal cancer.Among of them,42 patients,via artery,had been enrolled for concurrent interventional cisplatin,leucovorin,fluorouracil,hydroxy camptothecin chemotherapy plus radiotherapy.40 patients were given irradiation.Results The incidence rate of Ⅰ grade esophageal X-ray in the former group was 57.1%,and that in the later group was 25.0%,and the parameters had significant difference(?0.05).Conclusion Concurrent interventional cisplatin,leucovorin,fluorouracil,hydroxy camptothecin chemotherapy plus radiotherapy may be attributed to progression of Ⅳ stage middle-lower section esophageal cancer.
7.Icariin induces apoptosis of esophageal cancer cell through enhancing Fas-FasL expression activity
Xin JI ; Chong WANG ; Jie LI ; Xiaole YUE
Chongqing Medicine 2016;45(12):1608-1611
Objective To investigate the inhibitory effect of icariin(ICA) on the xenograft tumors growth of esophageal car‐cinoma and to preliminarily investigate its mechanism .Methods The MTT assay and Giemsa staining were applied to detect and observe the in vitro inhibitory effect of ICA on esophagus cancer cell lines Eca‐109 and TE‐13 .The xenograft tumor model of nude mouse esophagus cancer cell was constructed and divided into 3 groups ,6 cases in each group .Each mouse in the experimental group was intraperitoneally injected by ICA 50 mg/kg ;while the control group was injected by the same volume of normal saline and the positive control group was injected by cis‐platinum 2 mg/kg ,once every 2 days ,a total of 14 days .The tumor volume was measured once per 3 d .After experiment ,the tumor weight was measured;the TUNEL staining was used to observe the morphological chan‐ges and cell apoptosis of tumor tissue in each group .The changes of Fas and FasL protein expression in tumor tissues were analyzed by immunohistochemistry .The FasL and IFN‐γlevels in peripheral blood were tested by the ELISA assay .Results ICA exerted no obvious inhibitory effect on the proliferation of Eca‐109 and TE‐13 cell in vitro .The average volume and weight of xenografts tumor had statistical difference between the experimental group and the positive control group (P<0 .05) .The TUNEL staining results showed that the tumor tissues had obvious apoptosis ,the number of apoptosis cells was significantly increased compared with the control group(P<0 .05) .The immunohistochemistry experimental results showed that the expression of Fas and FasL was signifi‐cantly increased(P<0 .05) .The ELISA experimental results demonstrated that the FasL and IFN‐γlevels of peripheral blood in the experimental group were significantly increased(P<0 .05) .Conclusion ICA had no obvious inhibitory effect on esophageal cancer cell proliferation in vitro ,but could induce in vivo apoptosis through the Fas expression and secretion of FasL and IFN‐γ,thus plays the role of anti‐esophageal cancer .
10.The course of development, present situation and policy trends of neonatal resuscitation program
Hongbin LI ; Jie WANG ; Sumei JI ; Xiaoyan ZHANG ; Jianming GUO
Chinese Journal of Practical Nursing 2016;32(16):1273-1276
The neonatal resuscitation program consisted of three stages:pilot promotion, provinces promotion and grass-roots promotion in China. Neonatal resuscitation was easy to learn, training forms were various, the duration was different. There were regional differences in the pass rate of examination and standard recovery rate. The neonatal resuscitation training rate, the system execution rate and the equipment rate in primary hospitals was lower than secondary hospitals and tertiary hospitals. The primary hospitals would be the key link of the neonatal resuscitation program. We suggested to build neonatal resuscitation training and treatment system.