We report a case of para.psoriasis variegata in a 19 year-old male patient wha has brownish flat scaly papules that are confluent in a retiform pattern characterized by symmetrical distribution on trunk and upper extremities. A skin biopsy specimen showed hyperkeratosis, focaI parakeratosis, hyperpigmentation of basal cell layer, and a mild lymphocytic perivascular infiltrate. No evidence was found for a relationship to lymphoma.
Biopsy ; Humans ; Hyperpigmentation ; Lymphoma ; Male ; Parakeratosis ; Parapsoriasis* ; Skin ; Upper Extremity ; Young Adult

No abstract available.
Head* ; Orthognathic Surgery* ; Posture* ; Prognathism*

No abstract available.

No abstract available.
Apoptosis* ; Cell Line* ; Colon* ; Colonic Neoplasms* ; Etoposide*

No abstract available.
Prevalence* ; Ulsan*

PURPOSE: The purpose of this study was to develop in vivo dosimetries using both chromosomal aberrations and micronuclei in mice to assess biological effects of radiations. MATERIALS AND METHODS: Five each mice were irradiated with 0, 1, 2, 3, 4, 5, 10 Gy of Cs-137 gamma-rays. We scored numbers of chromosomal aberrations in metaphase spreads and numbers of micronuclei in bone marrow smears under light microscope, and obtained the dose-response relationships. We also examined the relationship between the two dose-response curves. RESULTS: The frequency of both chromosomal aberrations and micronuclei increased with dose, in a linear-quadratic manner. The delta, beta, and alpha coefficients were 0.0176, 0.0324, and 0.0567 for metaphase analysis (r=1.0, p<0.001) and 0.0019, 0.0073, and 0.0506 for micronuclei assay (r=1.0, p<0.001). The frequency of chromosomal aberrations and micronuclei in diffirent radiation doses was significantly correlated (r=0.99, p<0.01). CONCLUSION: In vivo dosimetry using either metaphase analysis or micronucleus assay was feasible in mice. These methods could be useful to evaluate biological effects of radiation.
Animals ; Bone Marrow Cells* ; Bone Marrow* ; Chromosome Aberrations ; Metaphase* ; Mice* ; Micronucleus Tests

PURPOSE: In children on anticancer chemotherapy, bloodstream infections (BSIs) are a major cause of morbidity and mortality. We investigated febrile episodes and bloodstream infections in pediatric cancer patients to guide proper selection of empiric antibiotics for febrile pediatric hemato-oncologic patients. METHODS: All febrile episodes treated in the division of hematology-oncology, the department of pediatrics, Hanyang University Hospital, between July 2005 and June 2008 were reviewed. Episodes with and without bloodstream infections were compared. RESULTS: Forty cases (18.9%, 25 patients) of BSI occurred in 212 febrile episodes (63 patients). Thirty-seven cases (23.6%, 22 patients) of BSI occurred in 157 febrile episodes with neutropenia (54 patients). Microorganisms identified in BSI corresponded to 23 gram-positive bacteria (51.2%), 20 gram-negative bacteria (44.5%), and 2 fungi (4.4%). Rates of BSI between those who had received umbilical cord blood transplantation and those who had received transplantation from other source were significantly different (55.0% vs. 7.7%, P=0.001). No differences in mortality rate were observed among organisms in BSI patients. For febrile episodes the rate of BSI was higher among those with Chemoport than those with Hickman catheter (P=0.029) and gram-positive pathogens were more likely to be associated with Chemoport (P=0.001). CONCLUSION: The study showed the rate of BSI, distribution of pathogens with regard to neutropenia, transplantation, central venous catheters, and antimicrobial susceptibility of pathogens in order to help guide in the choice of optimal empiric antibiotics in pediatric febrile neutropenic hemato-oncologic patients.
Anti-Bacterial Agents ; Bacteremia ; Catheters ; Central Venous Catheters ; Child ; Fetal Blood ; Fever ; Fungi ; Gram-Negative Bacteria ; Gram-Positive Bacteria ; Humans ; Neutropenia ; Pediatrics ; Transplants

We previously reported the result of the VDRL and TPHA tests among the general entertainers and prostitutes in the Youngdeungpo Ku, Chung Ku, Seoul and Paju area, Kyunggi province in 1979 The study resulted in an overall, VDRL reactive rate of 5 .6% in the 6, 666 subjects including general entertainers and prostitutes: 5 3% in the 5, 289 entertainers and 7.6% in the 837 prostitutes. 34.8% of VDRL reactive entertainers showed VDRL titers of 1: 8 or higher. In order to investigate the changing patterns of VDRL reactive rates in general entertainers and prostitutes, we compared the results of the present VDRL tests (1982) with those of our previous study (1979) Total 6, 808 subjects consisted of 2,931 residents who wanted to have medical certification from Jan. 4, 1982 to June 30, 1982 and 2, 562 general entertainers in the Youngdeungpo Ku and Chung Ku areas and 120 general entertainers and 1,195 prostitutes in the Paju area frorn Jan, 4, 1982 to Dec. 31, 1981. (countinued..)
Certification ; Gyeonggi-do ; Humans ; Seoul ; Serologic Tests* ; Sex Workers* ; Syphilis*

The serologic tests for syphilis including VDRL and TPHA tests were performed on generaI entertainers in Jung Ku and Young Deung Po Ku, and prostitutes including general entertainers in the Pa Ju area from January 1978 to June 1978. In the same period, direct vaginal smear with Gram stain and culture in Thayer-Martin media were carried. aut for all the general entertainers in Jung Ku and Young Deung Fa Ku as well as for the prostitutes in the Pa Ju area. The results were as follows: 1. An overall VDRL reactive rate of 5, 6 A was found among the 6, 666 general entertainers and prostitutes studied. The reactive rate of VDRL test was 5.3, in 5,289 general entertainers, and 7.6% among the 837 prostitutes in the Pa Ju area. 2. With regard to the VBRL quantitative test, the reactive rate of the group with a titration of 1: 8 or higher rvas 34.8, among the general entertainers of Young Deung Po Ku and Jung Ku. 3. The overall biologic false positive rate of VDRL test was 16.8% in the Young Deung Po Ku and Pa Ju areas using the TPHA test as the standard. 4. The positive rates of culture in Thayer-Martin media were 8.6% out of 1,387 general entertainers of Young Deung Po Ku and l.3% out of 4,352 in Jung Ku respectively, and 2.5 out of 326 prostitutes in the Pa Ju area. The findings seem to be probable that no remarkable change of the incidence of syphilitic and gonococcal infection has taken place recently among the genera. entertainers and prostitutes.
Humans ; Incidence ; Serologic Tests* ; Sex Workers* ; Syphilis ; Vaginal Smears

It has been shown that both rest and stress myocardial perfusion imagings with technetium agents can be performed on the same day using two different doses injected within few hours. The purpose of this study was to compare the two protocols (stress-rest and rest-stress) in detecting coronary artery diseases. One hundred and sixty patients (101 males, 59 females, mean age 57+/-9 years) and 120 patients (79 males, 41 females, mean age 59+/-10 years) underwent stress-rest myocardial perfusion SPECT and rest-stress myocardial perfusion SPECT, respectively All of them underwent both myocardial perfusion SPECT and coronary angiography within 1 month. A coronary stenosis was considered significant when it compromised the luminal diameter by> or =50%. The chi square test was used to compare differences in sensitivity, specificity and accuracy between the two groups. The overall sensitivity, specificity and accuracy of stress-rest protocol were 99%, 35%and 68%, respectively. Those of rest-stress protocol were 96%, 47%, and 78%, respectively. There was no difference between the two protocols in identifying individual diseased coronary artery branches. Therefore, one day stress-rest and rest-stress myocardial SPECT using Tc-99m agents were comparable and were very sensitive tests in detecting coronary artery diseases.
Coronary Angiography ; Coronary Artery Disease* ; Coronary Stenosis ; Coronary Vessels* ; Female ; Humans ; Male ; Perfusion Imaging ; Perfusion* ; Phenobarbital ; Sensitivity and Specificity ; Technetium ; Tomography, Emission-Computed, Single-Photon