1.The application of mitomycin-C in refractory esophageal strictures
Journal of Medical Postgraduates 2015;(11):1209-1212
Gastrointestinal benign stricture is one of common diseases in clinics , endoscopic dilation is its preferred treatment . However , for the dilation ineffective refractory strictures , it represents a difficult management problem given the limited therapeutic in-terventions available .Mitomycin-C is an antibiotic which has the dual role of anti-tumor and anti-proliferation.As an anti-proliferative drug, it was first applied in the field of ophthalmology .Local auxiliary application of MMC can be a feasible and safe measurement to improve the efficacy of refractory esophageal strictures .The aim of this study is to perform a systematic review which employs mitomycin C in the treatment of refractory esophageal strictures caused by corrosion , endoscopic submucosal dissection , esophageal atresia repara-tion and radiotherapy .
2.Clinical analysis for systemic complications of patients in the dental emergency room
Journal of Peking University(Health Sciences) 2015;(2):344-348
Objective:To analyze the clinical features of oral emergency patients in general health, and to guide the oral emergency patients in the treatment, and prevention of accidents.Methods:The retro-spective study was performed on the day visits to the emergency department in Peking University School and Hospital of Stomatology from February to November 2013.The basic information of the newly diag-nosed adult, their overall health status, American society of anesthesiologists(ASA) classification and oral diagnosis information were analyzed and summarized.Results:The cardiovascular and cerebrovascular diseases(6.4%), hypertension(13.4%), endocrine system diseases(4.2%)were most common in the patients.With the increase of age, the associated systemic diseases had increased in number and in ASA classification.Periapical disease ( 24.6%) , dental pulp disease ( 24.4%) , and periodontal disease (18.0%) accounted for about 2/3.Conclusion:The general health status of patients with oral emergen-cy worsened with the increase of age.Oral surgeons should make risk assessment before treatment.ASA classification system can help doctors predict the patient risk, take corresponding measures in advance, and help to reduce the occurrence of accidents.
3.Advances in mechanisms and treatment of portal vein thrombosis in patients with liver cirrhosis
Journal of Clinical Hepatology 2017;33(3):451-453
Portal vein thrombosis (PVT) refers to thrombosis in the main portal vein and portal vein branches and is an important complication of liver cirrhosis.PVT can aggravate portal hypertension,increase the risk of bleeding,and lead to acute ischemic necrosis of the small intestine in case of shedding or retrograde movement.This article focuses on the new points of view on the mechanisms and treatment of PVT in cirrhotic patients and points out that treatment regimen should be selected based on patients'overall conditions.
4.Ultrastructural changes of myocardium in cardiacglycosides toxicosis and the protective effect of mannitol
Chinese Journal of Pathophysiology 1989;0(06):-
ⅳ Hydroxyl scavenger, mannitol, in the dosage of 1.1mol/L 2g/kg and 3g/kg could increase LD_(100) of ouabain on guineapigs from 298.54?33.30 ?g/kg to 367.44?44.58 ?g/kg (P