Infantile hemangioendothelioma of the liver is a common vascular tumor in infancy. The tumor is usually multinodular or diffuse and classified into two types. We present a case of infantile hemangioendothelioma of the liver, which predominantly consists of type 2. A 4-month-old female was admitted for an evaulation of an abdominal distension. A CT scan of the liver showed a multinodular mass. The right lobectomy was done. Grossly, the mass consisted of round nodules ranging from 2cm to 5cm in diameter. Microscopically, the tumor revealed proliferation of small vascular channels lined by endothelial cells. Bizarre cells and mitotic cells were frequently noted. Vesicular nuclei and multilayering of the endothelial cells were also noted.
Endothelial Cells ; Female ; Hemangioendothelioma* ; Humans ; Infant ; Liver* ; Tomography, X-Ray Computed

BACKGROUND: There has been no clinical study of skin problems of the amputee in Korea and at Veterans Hospital, we have experienced so many skin problems of amputees. OBJECTIVE: We tried to observe skin problems of amputees and to relate them with sweating, poor hygiene, poor fit of socket, mechanical trauma, and duration of wearing prosthesis. METHODS: 125 extremity amputees who visited the Seoul Veterans Hospital during the period of 5 years from Jan. 1994 to Dec. 1998 were analyzed clinically. RESULTS: The study results are summarized as follows: 1. Among the 125 extremity amputees, the number of male patients was 124(99.2%) and that of female patients was 1(0.8%). The age distribution showed a peak incidence in the 7th decade(30.4%), followed by the 5th decade(28.8%), 6th decade(24.8%), and the mean age was 56.4 years. 2. The most common type of amputation was below the knee amputation(74 cases), the second was above the knee amputation(37 cases). 3. The duration of wearing prosthesis was above 20 years in 88 patients(70.4%), 16-20 years in 15(12%), 11-15 years in 11(8.8%), and 1-5 years in 6(4.8%). 4. The skin problems of the amputees were superficial fungal infection, chronic ulcer, intertriginous dermatitis, callus, corn, verrucous hyperplasia, verruca which were 63 cases(50.4%), 26 cases(20.80%), 17 cases(13.6%), 6 cases(4.8%), 5 cases(4%), 5 cases(4%), 3 cases(2.4%) respectively. 5. The predisposing factors of the dermatoses were mechanical trauma(84 cases) which acted as a cause of the chronic ulcer, intertriginous dermatitis, corn and callus, sweating(80 cases) and poor hygiene(11 cases) as those of superficial fungal infection, and poor fitting(6 cases) as that of verrucous hyperplasia. CONCLUSION: Superficial fungal infection and chronic ulcer were the main skin problems of the amputee. The longer the duration of wearing prosthesis, the more skin problems developed. The mechanical trauma and sweating were the major predisposing factors of stump dermatoses, especially of chronic ulcer and superficial fungal infection. Amputation is only the beginning of a long period of rehabilitation, and the treatment of the patient and the affected skin goes on for the rest of the patient's life. This clinical study suggests that the dermatologist must be concerned of the care of amputee's skin problems.
Age Distribution ; Amputation ; Amputees* ; Bony Callus ; Causality ; Dermatitis ; Extremities ; Female ; Hospitals, Veterans ; Humans ; Hygiene ; Hyperplasia ; Incidence ; Knee ; Korea ; Male ; Prostheses and Implants ; Rehabilitation ; Seoul ; Skin Diseases ; Skin* ; Sweat ; Sweating ; Ulcer ; Warts ; Zea mays

PURPOSE: The purpose of this study was to develop an online education on death, 'successful life, and beautiful death' for university students and to evaluate students' changes regarding perception of self and death. METHOD: A quasi-experimental design was used with one experimental group pre-post test. Subjects were 154 students who enrolled for online education about death for 16 weeks. SPSS/WIN 12 was used for analyzing data. RESULT: The results of the study clearly indicated this class had positive effects on students' perception of death-related concepts, attitudes toward death, and self-concept, showing statistically significant higher scores in post-tests than in pre-tests. In addition, the result of class evaluations showed a positive response, CONCLUSION: Findings suggested that this online education about death was effective to change students' perceptions of death related knowledge, attitude toward death, and self-concept. Recommendations for further studies were provided.
Adult ; *Attitude to Death ; Data Collection ; Data Interpretation, Statistical ; Female ; Humans ; Internet ; Male ; Models, Educational ; Perception ; Self Concept ; Students/*psychology

PURPOSE: The purpose of this study was to develop an evaluation instrument integrated and interdisciplinary death education for the human service areas such as nursing, social welfare, and education and to test the reliability and validity of it. METHOD: The subjects used to verify the instrument's reliability and validity were 407 students who were enrolled in the departments of nursing, social welfare, and education in universities located in Seoul, Pusan, Daegu, and Daejeon. The data was collected from April to May, 2005, and was analyzed by SPSS/WIN 12. RESULT: A factor analysis was conducted. Items with over a .40 factor loading and over a 1.0 eigen value were selected. Nine identified factors were learning about death, role of professionals, personal attitudes, hospice care, ethics and legal issues, death and dying, spiritual aspect of death, transcultural aspect of death, and multidisciplinary theory of death. The instrument consisted of 44 items and the reliability was a cronbach's of .953 CONCLUSION: Based on the study results, the content scale developed in this study was identified as a tool with a high degree of reliability and validity.
Thanatology ; Terminal Care ; *Questionnaires ; Professional Role ; Male ; Humans ; Hospice Care ; Female ; *Attitude to Death ; *Attitude of Health Personnel ; Adult

PURPOSE: The purpose of this study was to develop an evaluation instrument integrated and interdisciplinary death education for the human service areas such as nursing, social welfare, and education and to test the reliability and validity of it. METHOD: The subjects used to verify the instrument's reliability and validity were 407 students who were enrolled in the departments of nursing, social welfare, and education in universities located in Seoul, Pusan, Daegu, and Daejeon. The data was collected from April to May, 2005, and was analyzed by SPSS/WIN 12. RESULT: A factor analysis was conducted. Items with over a .40 factor loading and over a 1.0 eigen value were selected. Nine identified factors were learning about death, role of professionals, personal attitudes, hospice care, ethics and legal issues, death and dying, spiritual aspect of death, transcultural aspect of death, and multidisciplinary theory of death. The instrument consisted of 44 items and the reliability was a cronbach's of .953 CONCLUSION: Based on the study results, the content scale developed in this study was identified as a tool with a high degree of reliability and validity.
Thanatology ; Terminal Care ; *Questionnaires ; Professional Role ; Male ; Humans ; Hospice Care ; Female ; *Attitude to Death ; *Attitude of Health Personnel ; Adult

PURPOSE: The purpose of this study was to analyze death attitudes of students majoring in the human service area, such as nursing science, education, and social welfare. METHOD: The Q-methodology which provides a method of analyzing the subjectivity of each item was used. The 38 selected Q-statements from each of 42 subjects were classified into a shape of normal distribution using a 9 point scale. The collected data was analyzed using a QUANL PC program. RESULT: Four types of death attitudes for research subjects in nursing, education, and social welfare areas were identified. Type I is fatalistic admission, Type II is pursuit of existential life, Type III is uncertainty of life after death, and Type IV is separation-connection between life and death. CONCLUSION: The results of the study indicate that different approaches of death educational programs are recommended based on the four types of death attitudes.
Teaching ; Students, Nursing/*psychology ; Students/*psychology ; Social Work/*education ; Male ; Humans ; Female ; *Attitude to Death ; Adult

In an attermpt to aviod the deleterious effects of cardiopulmonary by pass such as pulmonary complication neurologic complication and renal failure off-pump CABG has been rediscovered and developed. We experienced off-pump CABG in 2 cases with unstable angina complicated with COPD and report herein the cases with review of literature.
Angina, Unstable* ; Coronary Artery Bypass ; Pulmonary Disease, Chronic Obstructive* ; Renal Insufficiency

OBJECTIVE: To evaluate female sexual function after colpoperineoplasty. METHODS: Women who visited regional clinic for colpoperineoplasty from June. 2004-Aug. 2004. filled in FSFI (The Female Sexual Function Index) questionnarie before and 4 months after surgery. Six weeks after surgery, they start pelvic muscle training with HMT 2000 (Korea, electric stimulator). RESULTS: Frequency of coitus, sexual desire, arousal, lubrication and orgasm was increased after colpoperineoplasty. Percentage of patients who had coitus more than once a week increased from 18% to 63%. In sexual desire, about 18% felt sexual arousal more than or about half the time before surgery, but increased to 45% after surgery. In sexual arousal, percentage of who felt sexually aroused during more than half of sexual activity increased from 34% before surgery to 69% after surgery. In Lubrication, percentage of who became lubricated during more than half of sexual activity increased from 44% before surgery to 82% after surgery. Who reached orgasm more than half of sexual activity increased from 29% before surgery to 70%. CONCLUSION: Colpoperineoplasty increased female sexual activity.
Arousal ; Coitus ; Female* ; Humans ; Lubrication ; Orgasm ; Sexual Behavior

OBJECTIVE: To identified whether serum Mullerian inhibiting substance (MIS) level may be used as a predictive marker of menopausal transition. METHODS: Serum MIS level was measured in reproductive women (n=87), in menopausal transition women (n=58), and in menopausal women (n=5) by ELISA. And we examined the immunohistochemical staining of the MIS in the ovarian tissues of 15 reproductive, 15 menopausal transition, and 5 menopausal women. RESULTS: 1. In the reproductive women, mean serum MIS level was 1.73+/-1.07 ng/ml. In the menopausal transition women, mean serum MIS level was 0.18+/-0.11 ng/ml. Serum MIS level did not show any significant fluctuation patterns according to follicular development. In menopausal transition women, serum MIS level was significantly lower than that of reproductive women (P<0.001). The cutoff value of serum MIS level for menopausal transition was 0.5 ng/mg. In the menopausal women, serum MIS level was not detected. 2. Serum MIS level was significantly decreased as patient age was increased. 3. In the reproductive group, the immunohistochemical staining demonstrated strong expression of MIS in the granulosa cells of the primary follicles and the growing follicles, but not in corpus luteum, preovulatory mature follicle, atretic follicle, and corpus luteum. In the menopausal transition women, immunohistochemical staining for MIS was observed in the nearly same pattern as that of thereproductive women, but with weaker expression. In the menopausal women, immunohistochemical staining of the MIS was not observed. CONCLUSION: MIS is a good candidate for predictive marker for ovarian aging and perimenopausal transition.
Aging ; Anti-Mullerian Hormone* ; Corpus Luteum ; Enzyme-Linked Immunosorbent Assay ; Female ; Granulosa Cells ; Humans ; Ovarian Follicle

Platelets are derived from the fragments that are formed from the cytoplasm of bone marrow megakaryocytes-small irregularly shaped anuclear cells. Platelets respond to vascular damage, contracts blood vessels, and attaches to the damaged region, thereby stopping bleeding, together with the action of blood coagulation factors. Platelet activation is known to affect genes associated with vascular risk factors, as well as with arteriosclerosis and myocardial infarction. Here, we performed a genome-wide association study with 352,228 single-nucleotide polymorphisms typed in 8,842 subjects of the Korea Association Resource (KARE) project and replicated the results in 7,861 subjects from an independent population. We identified genetic associations between platelet count and common variants nearby chromosome 4p16.1 (p = 1.46 x 10(-10), in the KIAA0232 gene), 6p21 (p = 1.36 x 10(-7), in the BAK1 gene), and 12q24.12 (p = 1.11 x 10(-15), in the SH2B3 gene). Our results illustrate the value of large-scale discovery and a focus for several novel research avenues.
Arteriosclerosis ; Blood Coagulation Factors ; Blood Vessels ; Blood Platelets ; Bone Marrow ; Cytoplasm ; Genome-Wide Association Study* ; Hemorrhage ; Humans ; Korea ; Megakaryocytes ; Myocardial Infarction ; Platelet Activation ; Platelet Count* ; Polymorphism, Single Nucleotide ; Risk Factors