1.Solid Facial Edema Refractroy to Various Treatment.
Ji Yoon CHOO ; Ji Hyun LEE ; Young Min PARK ; Jun Young LEE
Korean Journal of Dermatology 2016;54(7):579-580
No abstract available.
Acne Vulgaris
;
Edema*
2.A Case of Recurrent Uveitis in Autoimmune Liver Disease.
Ji Eob KIM ; Hun Gu CHOO ; Ie Na YOON
Journal of the Korean Ophthalmological Society 2014;55(8):1257-1260
PURPOSE: To report a case of recurrent uveitis associated with autoimmune liver disease. CASE SUMMARY: A 50-year-old female with severe fatigue and arthritis visited the ophthalmology department due to decreased visual acuity and discomfort in her right eye for ten days. She had intermittent injection and blurred vision in both eyes for 30 years. Slit lamp examination of her right eye showed keratic precipitates, pigment deposits on the anterior capsule of the lens and anterior chamber cells; fundus examination was normal without any sign of chorioretinitis. Inflammatory reaction was improved after steroid and cycloplegic eye drop treatment. Two months later, her left eye developed anterior uveitis. Inflammation was well controlled with steroid and cycloplegic eye drop treatment. To evaluate the cause of uveitis and associated systemic disease, serological testing was performed, and abnormal elevation of liver enzymes was detected. The patient was referred to the Gastroenterology Department and diagnosed with autoimmune liver disease. Oral ursodeoxycholic acid was prescribed. Liver function profile improved to normal range, and the patient is currently under routine follow-up with no sign of recurrent uveitis. CONCLUSIONS: When a patient with recurrent uveitis presents symptoms such as nausea, fatigue, abdominal pain, jaundice or abnormal liver profile, association with autoimmune liver disease should be considered.
Abdominal Pain
;
Anterior Capsule of the Lens
;
Anterior Chamber
;
Arthritis
;
Chorioretinitis
;
Fatigue
;
Female
;
Follow-Up Studies
;
Gastroenterology
;
Hepatitis, Autoimmune
;
Humans
;
Inflammation
;
Jaundice
;
Liver
;
Liver Diseases*
;
Middle Aged
;
Nausea
;
Ophthalmology
;
Reference Values
;
Serologic Tests
;
Ursodeoxycholic Acid
;
Uveitis*
;
Uveitis, Anterior
;
Visual Acuity
3.Cutaneous Metastasis of Giant Cell-Rich Osteosarcoma.
Ji Yoon CHOO ; Ji Hyun LEE ; Jun Young LEE ; Young Min PARK
Annals of Dermatology 2016;28(2):247-248
No abstract available.
Neoplasm Metastasis*
;
Osteosarcoma*
4.Cutaneous Metastasis of Giant Cell-Rich Osteosarcoma.
Ji Yoon CHOO ; Ji Hyun LEE ; Jun Young LEE ; Young Min PARK
Annals of Dermatology 2016;28(2):247-248
No abstract available.
Neoplasm Metastasis*
;
Osteosarcoma*
5.Increased expression of dopamine receptors and transporter and hypomethylation of dopamine transporter gene in uterine leiomyoma.
Ju Hyun KIM ; Min Ji KIM ; Young Ahe CHOO ; Yoon Suk CHOI ; Tae Sung LEE ; Hong Tae KIM
Korean Journal of Obstetrics and Gynecology 2005;48(3):628-637
OBJECTIVE: Dopamine plays a key role in the proliferation regulation of the smooth muscle cells. The purpose of this study was to observe the degree of expression of dopamine D1 and D2 receptors and dopamine transporter (DAT) and to evaluate the influence of methylation about control of expression of DAT in uterine leiomyoma and normal myometrial tissue. METHODS: In 20 patients who underwent hysterectomy due to uterine leiomyoma, normal myometrial and leiomyoma specimens were obtained. The expression of dopamine D1 and D2 receptors and DAT was demonstrated by using RT-PCR and immunohistochemistry in each normal myometrium and leiomyoma. Analysis of the DNA methylation status of DAT was conducted using HpaII digestion and the methylation-sensitive PCR. RESULTS: The mRNA level of dopamine D1 receptor was relatively higher in normal myometrium than D2 receptor and it was also unchanged in leiomyomas. However, the mRNA levels of dopamine D2 receptor and DAT in leiomyomas were much higher than normal myometrium. Consistent with elevated mRNA levels, high levels of dopamine receptors protein expression were detected by immunohistochemistry in leiomyomas. The degree of methylation at CpG sites of the area intron 1 of DAT (genomic position, +377 - +888) was decreased in leiomyomas. CONCLUSION: These results suggest that overexpressed dopamine D2 receptor and DAT would be associated with proliferation of human uterine leiomyomas and the methylation status of the CpG island of DAT determines its expression.
Animals
;
CpG Islands
;
Digestion
;
DNA Methylation
;
Dopamine Plasma Membrane Transport Proteins*
;
Dopamine*
;
Female
;
Humans
;
Hysterectomy
;
Immunohistochemistry
;
Introns
;
Leiomyoma*
;
Methylation
;
Mice
;
Myocytes, Smooth Muscle
;
Myometrium
;
Polymerase Chain Reaction
;
Receptors, Dopamine D1
;
Receptors, Dopamine D2
;
Receptors, Dopamine*
;
RNA, Messenger
6.Prevalence and Treatment Efficacy of Genitourinary Mycoplasmas in Women with Overactive Bladder Symptoms.
Young Suk LEE ; Ji Yoon KIM ; Joon Chul KIM ; Won Hee PARK ; Myung Soo CHOO ; Kyu Sung LEE
Korean Journal of Urology 2010;51(9):625-630
PURPOSE: To evaluate the incidence of genitourinary mycoplasmas and the efficacy of antibiotics in women with overactive bladder (OAB) symptoms. MATERIALS AND METHODS: Women with OAB symptoms (micturition > or =8/24 hours and urgency > or =1/24 hours) for > or =3 months were screened for Mycoplasma hominis (M. hominis), Ureaplasma urealyticum (U. urealyticum), and Chlamydia trachomatis (C. trachomatis). Specimens from urethral and cervical vaginal swabs were examined for M. hominis and U. urealyticum by using the Mycoplasma IST2 kit and for C. trachomatis by using PCR. Women with positive results were treated with a 1 g dose of azithromycin. Persistent infection was treated with doxycycline. Changes in a 3-day bladder diary, Patient Perception of Bladder Condition (PPBC), and International Consultation on Incontinence Questionnaire-Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) were evaluated 4 weeks after negative conversion. Patient satisfaction was assessed. RESULTS: Of 84 women screened, 42.8% were positive (U. urealyticum, 40.5%; M. hominis, 7.1%; C. trachomatis, 3.6%; two organisms, 8.3%). After treatment, 82.7% obtained negative conversion, and their median number of micturition episodes decreased from 10.6/24 hours to 8.1/24 hours (p=0.002). PPBC and domain scores of the ICIQ-FLUTS (filling and quality of life) significantly improved. About 87.5% women with negative conversion were satisfied with the treatment. CONCLUSIONS: Considering diagnostic tests and treatment for genitourinary mycoplasmas might be beneficial before invasive workup or treatment in women with OAB symptoms.
Anti-Bacterial Agents
;
Azithromycin
;
Chlamydia trachomatis
;
Diagnostic Tests, Routine
;
Doxycycline
;
Female
;
Humans
;
Incidence
;
Lower Urinary Tract Symptoms
;
Mycoplasma
;
Mycoplasma hominis
;
Patient Satisfaction
;
Polymerase Chain Reaction
;
Prevalence
;
Treatment Outcome
;
Ureaplasma urealyticum
;
Urinary Bladder
;
Urinary Bladder, Overactive
;
Urination
7.A Case of Alstrom Syndrome.
Kun Ho YOON ; Ho Young SON ; Sung Koo KANG ; Yoon Hee CHOI ; Bong Yeon CHA ; Hwan Suk CHO ; Ki Bum KIM ; Ji Ho KANG ; Young Mi CHOO ; Sang Soo BAE
Journal of Korean Society of Endocrinology 1998;13(3):501-508
The Alstrom syndrome is inherited autosomal recessive disorder, characterized by obesity, diabetes mellitus, pigmentary retinal degeneration, normal intelligence, sensorineural hearing loss, baldness, acanthosis nigricans, male hypogonadism, hyperuricemia and hypertriglyceridemia. There is no reported case of Alstrom syndrome in Korea yet. We experienced a 29-year-old female patient with clinical characteristics similar to Alstrom syndrome who was admitted due to poorly controlled diabetes mellitus and diabetic retinopathy with hemorrhage. We report this case with the review of literatures.
Acanthosis Nigricans
;
Adult
;
Alopecia
;
Alstrom Syndrome*
;
Diabetes Mellitus
;
Diabetic Retinopathy
;
Female
;
Hearing Loss, Sensorineural
;
Hemorrhage
;
Humans
;
Hypertriglyceridemia
;
Hyperuricemia
;
Hypogonadism
;
Intelligence
;
Korea
;
Male
;
Obesity
;
Retinal Degeneration
8.Clinical characteristics and outcome of invasive Prevotella infection.
Ji Yeol YOON ; Eun Ju CHOO ; Sang Ho CHOI ; Mi Na KIM ; Nam Joong KIM ; Yang Soo KIM ; Jun Hee WOO ; Ji So RYU ; Mee Soo CHANG
Korean Journal of Medicine 2003;64(3):254-259
BACKGROUND: Prevotella species is one of the major microoranism responsible for invasive anaerobic bacterial infection. This study was performed to investigate the clinical characteristics and outcome of invasive Prevotella infection in a University affiliated, tertiary care Hospital. METHODS: We obtained the information from the computerized data base of the clinical microbiology laboratory from January 1997 to December 2000, and identified patients whose sterile clinical specimen culture had yielded Prevotella species. We then reviewed the patients' medical records, and studied demographic, clinical, and microbiologic data. RESULTS: The total of 34 patients with invasive Prevotella infection were enrolled for the analysis. Seventeen strains were isolated from blood, 13 from the pleural fluid, 5 from the ascites, and 1 from both the ascites and blood. Half of the cases of Prevotella infection were mixed-infection and 22 cases (64.7%) were of community origin. Twenty-six patients (76%) were men and the mean age was 59 years. Most common underlying disease was malignant neoplasms (19/34, 55.9%). A portal of entry could be determined in 29 patients (85.3%) with the most common being the respiratory tract (12/34, 35.3%), followed by the gastrointestinal tract (6/34, 14.4%), and the wound site (6/34, 14.4%). Surgical procedure was necessary for 21 cases (63.5%). One-month mortality was 32.3%. The mortality was significantly associated with the underlying chronic renal failure (p=0.028) and ICU care (p=0.002). Surgical therapy had a protective effect (54% vs 14%, p=0.022) CONCLUSION: Invasive Prevotella Infections were more prevalent among old age patients with underlying malignancy than younger people and frequently necessitated surgical procedure. Early surgical treatment would decrease mortality.
Aged
;
Ascites
;
Bacterial Infections
;
Gastrointestinal Tract
;
Humans
;
Kidney Failure, Chronic
;
Male
;
Medical Records
;
Mortality
;
Prevotella*
;
Respiratory System
;
Tertiary Healthcare
;
Wounds and Injuries
9.Immunohistochemistry and Polymerase Chain Reaction for Detection Human Papilloma Virus in Warts: A Comparative Study.
Hong Sun LEE ; Ji Hyun LEE ; Ji Yoon CHOO ; Hee Jin BYUN ; Jin Hyun JUN ; Jun Young LEE
Annals of Dermatology 2016;28(4):479-485
BACKGROUND: Immunohistochemistry and polymerase chain reaction (PCR) are the most widely used methods for the detection of viruses. PCR is known to be a more sensitive and specific method than the immunohistochemical method at this time, but PCR has the disadvantages of high cost and skilled work to use widely. With the progress of technology, the immunohistochemical methods used in these days has come to be highly sensitive and actively used in the diagnostic fields. OBJECTIVE: To evaluate and compare the usefulness of immunohistochemistry and PCR for detection human papilloma virus (HPV) in wart lesions. METHODS: Nine biopsy samples of verruca vulgaris and 10 of condyloma accuminatum were examined. Immunohistochemical staining using monoclonal antibody to HPV L1 capsid protein and PCR were done for the samples. DNA sequencing of the PCR products and HPV genotyping were also done. RESULTS: HPV detection rate was 78.9% (88.9% in verruca vulgaris, 70.0% in condyloma accuminatum) on immunohistochemistry and 100.0% for PCR. HPV-6 genotype showed a lower positivity rate on immunohistochemistry (50.0%) as compared to that of the other HPV genotypes. CONCLUSION: Immunohistochemistry for HPV L1 capsid protein showed comparable sensitivity for detection HPV. Considering the high cost and great effort needed for the PCR methods, we can use immunohistochemistry for HPV L1 capsid protein with the advantage of lower cost and simple methods for HPV detection.
Biopsy
;
Capsid Proteins
;
Genotype
;
Human papillomavirus 6
;
Humans*
;
Immunohistochemistry*
;
Methods
;
Papillomaviridae*
;
Polymerase Chain Reaction*
;
Sequence Analysis, DNA
;
Warts*
10.Squamous Cell Carcinoma Derived from Bowenoid Papulosis of the Vulva.
Ji Yoon CHOO ; Gyeong Sin PARK ; Hee Jin JUN ; Ji Hyun LEE ; Young Min PARK ; Jun Young LEE
Korean Journal of Dermatology 2017;55(4):279-280
No abstract available.
Carcinoma, Squamous Cell*
;
Epithelial Cells*
;
Vulva*