1.Application of phototherapy and its related problems on neonatal hyperbilirubinemia
International Journal of Pediatrics 2013;(3):272-274
Phototherapy is the most common and effective method to intervene and treat neonatal hyperbilirubinemia in clinic.The application of phototherapy varies from gestational age,birth weight,age and many other factors.Beside the traditional phototherapy instruments,more advanced high-intensive phototherapy instruments are applied to phototherapy.With the increasing application of phototherapy,many problems have showed up.This paper reviews based on the research of the indication,clinical application and adverse reactions on phototherapy.
2.FEASIBILITY OF SCREENING FOR ANTIBODY TO HIV BY POOLING THE SERUM SPECIMENS
Chinese Journal of Blood Transfusion 1988;0(01):-
The feasibility of screening for antibody to HIV by pooling 10 serum specimens was demonstrated in this experiment. The test was conducted using the reagent developed by Organon Teknika corporation (U. S. A) for testing for antibody to HIV by ELISA. The determination was made by changing only the ratio between the serum specimen volume and the serum specimen diluent volme, with their total volume being constant. When the serum specimen volume was increased from 5to 59?l as a result of pooling 10 serum specimens, while the serum specimen diluent volume was correspondingly decreased, the optical density of the pooled serum specimens was somewhat raised, but it was always below cutoff value, indicating that the specificity of test did not be subjected to any influence. In addition, when one serum specimen estabished as being positive intesting for antibody to HIV, and nine serum specimens from normal donors were pooled, the serum specimen containing the antibody to HIV had exactly been shown through multiple paired tests, indicating that the serumpooling method did not have any influence on the test sensitivity and could reach the level of original method. The serum-pooling method could be easy to spread because of its many advantages, such as saving the expenditure by 10 times, saving the manpower and material resource, and saving the working hours. (Original article on page 5)
3.Effect of NGF on Release of NO From Peritoneal Macrophages in Mice
China Pharmacy 2001;0(07):-
OBJECTIVE:To investigate the effect of NGF on release of NO from peritoneal macrophages in mice METHODS:The content of NO in macrophages was detected with Griess agent RESULTS:NGF,in concentration of 0 73mg~5 83mg free amino acid per ml,could significantly inhibit release of NO from peritoneal macrophages in mice CONCLUSION:Inhibiting NO release may be one of the mechanism of NGF in protecting neurons
4.Effect of thymopeptide on LPS-induced release of nitric oxide from mouse peritoneal microphase in vitro
Chinese Journal of Biochemical Pharmaceutics 2001;22(2):74-75
Purpose The aim is to investigate the effects of thymopeptide on LPS-induced release of nitric oxide (NO) from mouse peritoneal microphase in vitro.Methods NO was detected by Griess reagent.Results Thymopeptide 83.3~333.3 μg/ml reduced NO synthesis and secretion from mouse peritoneal microphase in vitro significantly.Conclusion The effects of thymopeptide on LPS-induced release of NO from mouse peritoneal microphase may be one of mechanisms of its pharmacological effect.
5.Preliminary cbservation on the safety of Sumianxin Ⅱ combined with Diazepam for anesthesia in the periodontal surgery in Beagle dogs
Journal of Chongqing Medical University 2007;0(09):-
Objective:To observe the anesthetic effects of SumianxinⅡ combined with diazepam on the Beagle dogs in experimental periodontal surgery to Provide the reference. Methods:Healthy adult male Beagle dogs were anesthetized with SumianxinⅡat the doses of 0.05、0.1、0.15 ml/kg in the combination group and diazepam(0.1 ml) by hip intramuscular injection simultaniously. Added injection dosage was half of the first dosage. Healthy adult Beagle dogs in the contral group were only anesthetized with SumianxinⅡ at the doses of 0.05、0.1、0.15 ml/kg by hip intramuscular injection. The time of adding anesthetic was not sure in surgery. Anesthesia induction period,initial duration of anesthesia,and adverse reactions after anesthesia were compared between the two groups. Results: The combined treatment group induction dose respectively (11.00?1.41) min,(9.00?0.82) min,(12.75?0.50) min,For the first time maintaining anesthesia(29.75?6.62) min,(46.00?5.29) min,(45.25?6.02) min,Intraoperative additional one times longer cansustain anesthesia for(38.75?3.50) min,(45.25?4.03) min,(37.25?2.75) min. Pure Sumianxin Ⅱ new standards of sleep narcotic induction respectively respectively was (15.75?2.50) min,(14.25?2.99) min,(14.50?2.08) min,For the first time maintaining anesthesia was (20.75?5.19) min,(20.5?3.42) min,(22.25?5.19) min,the time of adding anesthetic was not sure in surgery. 2 Dogs died in SumianxinⅡ group. United drug group simple Sumianxin Ⅱ induction period in each group by t test,Sumianxin Ⅱat the doses of 0.1 ml/kg supplemented with 0.3 ml dose stability (P
6.Antiphospholipid syndrome.
Chinese Journal of Pediatrics 2003;41(2):154-157
Abortion, Habitual
;
complications
;
Antibodies, Antiphospholipid
;
blood
;
Antiphospholipid Syndrome
;
complications
;
pathology
;
therapy
;
Erythema
;
complications
;
Heart Valve Diseases
;
complications
;
Humans
;
Kidney Diseases
;
complications
;
Skin Diseases
;
complications
;
Thrombosis
;
complications
8.Application of Humanistic Psychological nursing intervention in laparoscopic resection of bladder tumor and ileal bladder tumor
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):376-377
Objective To study and analyze the application of Humanistic Psychological Intervention in the operation of laparoscopic bladder tumor resection and ileal neobladder. Methods 100 cases of laparoscopic bladder tumor resection and ileal neobladder were selected from February 2015 to December 2016 in our hospital as the study subjects, and randomly divided into the control group and the experimental group, with 50 patients in each group. The patients in control group received routine nursing care, while the experimental group received Humanistic Psychological Intervention Nursing in operation room. The nursing satisfaction and related clinical indicators were compared in the two groups. Results After the corresponding nursing, the total satisfaction in the experimental group was 47 cases (94%), the total satisfaction in the control group was 36(72%). The satisfaction degree of the patients in the experimental group was significantly higher than that in the control group, the difference was statistically significant (P<0.05). The hospitalization time and operation time of the experimental group were significantly shorter than those of the control group, and the amount of bleeding in the control group was significantly higher than that in the experimental group, the difference was statistically significant (P<0.05). Conclusion The application of operation room humanized psychological intervention after resection of ileal neobladder surgery in laparoscopic bladder tumor can improve nursing satisfaction to a large extent, improve the treatment effect of the patients, help patients recover, with further clinical promotion and application significance.
9.Analysis on levels of serum adiponectin and homocysteine in elderly patients with type 2 diabetes complicating retinopathy
Chongqing Medicine 2016;45(33):4669-4671,4674
Objective To explore the levels of serum adiponectin(APN)and homocysteine(Hcy)in elderly patients with type 2 diabetes metlitus(T2DM)complicating retinopathy and the relation between these two indicators.Methods Sixt-eight cases of complicating retinopathy(T2DM+DR group)were screened from the elderly inpatients with T2DM in our hospital from January 2012 to December 2014.Their general data were investigated.The routine biochemical indicators were tested.The enzyme-linked immunosorbent assay(ELISA)was employed to measure the serum total APN,high molecular weight APN and Hcy levels.Mean while the correlation among total APN,high molecular weight APN and Hcy was evaluated by adopting the Pearson correlation analysis.Contemporaneous 65 cases of elderly T2DM and 70 elderly people undergoing the healthy physical examination were chosen as the T2DM group and NC group respectively.Results The WHR,FBP,TC,TG,LDL-C,HbA1c,FINS and HOMA-IR in the T2DM+DR group and T2DM group were higher than those in the NC group,while the HDL-C level was lower than that in the NC group(P<0.05);the duration and BMI of the T2DM-4-DR group were higher than those of the T2DM group,the difference was statistically significant(P<0.05);the levels of total APN and high molecular weight APN in the T2DM+DR group and T2DM group were lower than those in the NC group,while the Hcy level was higher than that in the NC group(P<0.05);moreover the levels of total APN and high molecular weight APN in the T2DM+DR group were lower than those in the T2DM group,and Hey level was higher than that in the T2DM group,the difference was statistically significant(P<0.05);the levels of total APN(r=-0.654)and high molecular weight APN(r=-0.562)were negatively correlated with the Hey level in the T2DM+DR group(P< 0.05).Conclusion The serum APN level is decreased and Hcy level is increased in elderly patients with T2DM complicating retinopathy,which may be associated with the progression of retinopathy in T2DM.
10.Transurethral Resection of Bladder Tumor:A Report of 26 Cases
Chinese Journal of Minimally Invasive Surgery 2005;0(08):-
Objective To investigate the efficacy of transurethral resection of bladder tumor(TURBT).Methods From August 2001 to January 2007,26 patients with bladder tumor were treated with TURBT.Cutting electrode was used to resect the tumor,including also the normal mucous membrane,away from the base of the tumor by 0.5-1.0 cm,and reaching shallow muscle layer of the bladder in depth.The wound was treated with electrocoagulation.Postoperatively,drugs such as mitomycin were used through intravesical instillation for chemotherapy.Results Operation time was 15-90 min(52.5?37.5 min).One case had serious postoperative bleeding of the bladder,1 case of bladder perforation.Follow-up was conducted in 22 cases for 0.5-2 years,(mean:1 year).Six cases had recurrence in which 4 were in situ,the other 2 were ectopia.One of the recurrent cases had chyluria,treated with ligation of renal lymphatic tissue.Conclusions TURBT has advantages such as simple surgical manipulation,and reliable efficacy etc,in treating bladder tumor.