Objective To improve the traditional treatment of retrograde pulpitis, using Periocline adjuvant therapy, to evaluate its clinical effect.Methods From January 2015 to 2017 in January, our hospital 70 patients treated with retrograde pulpitis.The patients were randomly divided into two groups.The observation group of 35 cases, adopt the traditional treatment methods (periodontal treatment and dental pulp treatment), 35 cases in the control group based on conventional therapy, the adjuvant treatment of periocline.The related indexes and treatment effects were observed.Results After treatment, the indexes of the two groups of patients were significantly decreased compared with the control group[(1.57±0.50),(3.37±1.88),(4.89±1.60),(5.31±1.39)],the observation group decreased much more[(0.79±0.24),(2.01±1.14),(4.01±1.38),(4.11±0.62)], the difference was significant (P<0.05).At the same time, the effective rate of the observation group was 94.29% (33 cases), and the effective rate of the control group was 74.29% (26 cases), the difference was significant (P<0.05).Conclusion Based on conventional therapy, using Periocline adjuvant therapy, can improve the therapeutic effect of retrograde pulpitis, has significant value of application and promotion.

Objective To investigate the effects of minocycline hydrochloride ointment on collagenase in gingival crevicular fluid.Methods 60 patients with chronic periodontitis treated in our hospital from January 2015 to December 2016 were selected as the research object, the patients were divided into two groups according to their intervention methods, 30 cases in each group.The control group was treated with ultrasound clean governance and iodine glycerol, the observation group was treated with ultrasound clean governance and minocycline hydrochloride ointment The experimental data of the two groups were compared.Results The index change of gingival crevicular fluid volume plaque index,,depth of exploration and clinical attachment loss in the observation group were better than those in the control group, the difference between the two groups was statistically significant (P<0.05);The clinical therapeutic effect of the observation group(93.3%)was better than that of the control group(73.3%), and the difference between the two groups was statistically significant (P<0.05).The incidence of adverse reactions in the observed group(10.0%)was lower than that in the control group(26.7%), and the difference between the two groups was statistically significant (P<0.05).Conclusion Minocycline hydrochloride ointment can affect the level of collagenase in gingival crevicular fluid, and the clinical effect of the treatment of chronic periodontal disease is significant.

Objective To study the effect of minocycline hydrochloride ointment and ibuprofen on serum concentration of chronic periodontitis . Methods 86 patients with chronic periodontitis treated in our hospital from June 2014 to June 2016 were selected and randomly divided into two groups:observation group 43 cases, using minocycline hydrochloride ointment combined with ibuprofen treatment , the control group 43 cases, only the use of minocycline hydrochloride ointment for treatment.After treatment, the clinical efficacy of the two groups were observed, the level of plaque, the level of attachment, the level of gingival sulcus bleeding and the probing depth of periodontal pocket were recorded, the levels of IL-10, TNF-α, hs-CRP and IL-8 in serum and the incidence of adverse reactions were measured.Results The total effective rate was 90.7% in the observation group and 74.4%in the control group, which was significantly higher than that in the control group, the difference was statistically significant (P<0.05).The probing depth of the periodontal pocket, gingival sulcus bleeding index, attachment level and plaque index decreased to varying degrees in the two groups before and after treatment, the difference was statistically significant (P<0.05), patients in the observation group were significantly lower than those in the control group, the difference was statistically significant (P<0.05).After treatment, the levels of IL-8, hs-CRP and TNF-αin serum of the two groups decreased, IL-10 levels increased in different degrees, the difference was statistically significant (P<0.05).The observation group was better than the control group, the difference was statistically significant ( P<0.05 ) .Conclusion Minocycline hydrochloride ointment combined with ibuprofen has a good effect on patients with chronic periodontitis.It can effectively relieve the patient's condition and improve the serum concentration of patients.

Coix seed has anti-tumor effect and the anti-tumor activity composition is coix seed oil. Researches show that inducing cancer cell apoptosis and angiogenesis inhibition and regulation of the immune and analgesic function are the major roles of coix seed oil. Clinical researches prove that the effect can be increased and the life quality of lung cancer patients can be improved and the survival time can be prolonged when coix seed oil is used to treating lung cancer combined with Chemotherapy and Radiotherapy. So it is widely used in the treatment of lung cancer.

To observe the clinical effect of oblique puncture plus plucking manual technique for fatigue periositis of tibia.Methods:60 cases of the patients with fatigue Deriostitisof tibia were randomly divided into the treatment group of 30 cases treated by oblique puncture plus plucking manual technique,and the control group of 30 cases treated by ultra short wave.Resuits:The curative rate was 60.0% in the treatment group and 20.0% in the control group.and the total effective rate was 93.3% and 70.O% respectively.The therapeutic effect was better in the treatment group than in the control group (P＜0.05).Conclusion:Oblique puncture plus plucking manual technique has a better therapeutic effect for fatigue periostitis of tibia.

Adolescent ; Child ; Humans ; Male ; Nephritis, Interstitial ; pathology ; Uveitis ; pathology

Adenoma ; pathology ; Biopsy ; Carcinoma in Situ ; pathology ; Cell Transformation, Neoplastic ; Colitis, Ulcerative ; pathology ; Colorectal Neoplasms ; diagnosis ; pathology ; Crohn Disease ; pathology ; Gastric Mucosa ; pathology ; Humans ; Intestinal Mucosa ; pathology ; Precancerous Conditions ; diagnosis ; pathology ; Stomach Neoplasms ; diagnosis ; pathology

OBJECTIVETo construct a 3D finite-element model of the craniofacial complex with the original DICOM data of CT and to investigate the preliminary biomechanical characteristics with different directions and magnitudes of retractive forces to the maxilla of rhesus monkeys.

METHODSA male rhesus monkey with mixed dentition was used. Spiral CT was performed to establish a 3D finite-element model of the craniofacial complex. The ANSYS 12.1 software was used to analyze craniofacial complex displacement.

RESULTSEach landmark showed larger displacement with increasing force value. The displacement values and force size exhibited a linear relationship. In the x-axis direction, all displacements were small. In the y-axis direction, all displacements showed significantly higher changes with increasing force value displacement. In the z-axis direction, the A-point and ANS point moved downward, but PNS moved upward.

CONCLUSIONLoading retractive force resultes in an apparent backward and clockwise rotation on the maxilla with no obvious effects on the width of the upper jaw.

Objective:To establish a method to determine vitamin B 6 and fluocinonide in compound vitamin B 6 gel.Methods:The contents of vitamin B6 and fluocinonide in the gel were determined by HPLC with a Lichrospher CN C 18column (250 mm ×4.6 mm, 5μm).The mobile phase was heptane sulfonate solution (adding 6.8 g potassium phosphate monobasic and 1.0 g heptane sulfonate into 1000 ml water) -methanol –triethylamine (35:65:0.2,adjusting pH to 3.2 with phosphoric acid).The detection wavelength was 238 nm and the column temperature was 25℃.The injection volume was 20 μl.Results: Vitamin B6 had a good linear relationship within the range of 15.0-300.0 μg· ml-1(r=1.000 0), and the average recovery was 99.65% (RSD=0.3, n=9).Fluocinonide had a good linear relationship within the range of 0.4-8.0 μg· ml-1 (r=0.9990), and the average recovery was 99.35% (RSD=0.85, n=9).Conclusion:The method is simple and reproducible, and the result is accurate.The method can be used for the deter-mination of the gel.

To investigate the damage on macrophage of the commercial peritoneal dialysis solution(CDS). Methods Macrophages were seperated from peritoneal fluid remained overnight of seven CAPD patients and TNF-a level of supernatant was determined and compared with those macrophages from uremic patients not yet recieving peritoneal dialysis. Results TNF-a levels of different glucose concentration decreased obviously in experimental group compared with control group, especially lower in 2.5% and 4.25% group. Conclusion In vivo experiment confirms that CDS possesses a long time inhibition on macrophage and this inhibition varies with different glucose concentrations.