2.Genes Associated with Radiation Adaptive Response Induced by Low Level Radiation from (99m)Tc in Human Cell Lines.
An Sung KWON ; Hee Seung BOM ; Chan CHOI ; Ji Yeul KIM ; Wook Bin LIM
Korean Journal of Nuclear Medicine 2001;35(5):313-323
No abstract available.
Cell Line*
;
Humans*
3.Prenatal Diagnosis of TRAP sequence: A Case REport -Usefulness of Color Doppler Sonography-.
Ji Hee RYU ; Hyung Min CHOI ; Y W PARK ; Jae Sung CHO ; Jae Wook KIM
Korean Journal of Perinatology 1997;8(3):302-308
Twin reversed arterial perfusion (TRAP) sequence is a rare specific anomaly of twin gestation with fused placenta and umbilical anastomosis. This syndrome occurs once in about 34,600 births and reported first by Beneditti in 1533. We report on prenatal diagnosis of a case of TRAP sequence with color Doppler sonography, this case is presented with a brief review of the literature.
Humans
;
Parturition
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Perfusion
;
Placenta
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Pregnancy
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Prenatal Diagnosis*
4.Development of a Two Triplex Real-Time Polymerase Chain Reaction for Rapid Detection of Six Carbapenemase Genes in Enterobacteriaceae
Ji Ae CHOI ; Song Mee BAE ; Jung Wook KIM ; Kwang Jun LEE
Osong Public Health and Research Perspectives 2020;11(1):53-59
Carbapenem resistance is a serious clinical and public health threat. Carbapenemase can confer carbapenem resistance, and most carbapenemase genes are plasmid encoded so resistance can easily spread. In this study, we aimed to develop a novel system based on the TaqMan platform for the rapid detection of 6 clinically prevalent carbapenemase genes: The triplex assay was verified by testing genomic DNA of 6 carbapenemase-producing No amplification was detected among the negative samples. The result showed 100% concordance with the genotypes previously identified. The entire assay, including DNA extraction and real-time PCR, was completed within 2 hours. The newly developed triplex real-time PCR assay was useful for the rapid, accurate and simultaneous detection of 6 carbapenemase genes in Enterobacteriaceae, suggesting its potential to allow an early decision on the appropriate treatment, management, and prevention of the spread of resistant infections in hospitals.
5.Primary Angiosarcoma of the Mesentery: A Case Report
Hyeon Wook KANG ; Ji Yeol SHIN ; Ju Wan CHOI
Journal of the Korean Radiological Society 2020;81(2):423-427
Angiosarcoma is a malignant endothelial cell tumor of lymphatic or vascular origin and is most commonly found in the skin and soft tissue. Primary mesenteric angiosarcoma has rarely been reported. Here, we present a case of primary mesenteric angiosarcoma manifesting as a gradually enhancing mass along with necrosis and hemorrhage.
6.Primary Angiosarcoma of the Mesentery: A Case Report
Hyeon Wook KANG ; Ji Yeol SHIN ; Ju Wan CHOI
Journal of the Korean Radiological Society 2020;81(2):423-427
Angiosarcoma is a malignant endothelial cell tumor of lymphatic or vascular origin and is most commonly found in the skin and soft tissue. Primary mesenteric angiosarcoma has rarely been reported. Here, we present a case of primary mesenteric angiosarcoma manifesting as a gradually enhancing mass along with necrosis and hemorrhage.
7.A Case of Infectious Arthritis due to Staphylococcus lugdunensis in Seronegative Rheumatoid Arthritis, Diabetes Mellitus Patient, after Intraarticular Hyaluronic Acid Injection.
Ji Wook CHOI ; Yeong Seop YUN ; Young Jae DOO ; Kyung Joong KIM ; Jong Wook KIM ; Ji Min OH
Journal of Rheumatic Diseases 2016;23(5):321-325
Intra-articular hyaluronic acid injections for symptomatic treatment of osteoarthritis are widely used but can result in complications, such as infectious arthritis. Staphylococcus lugdunensis is a common normal skin flora but can cause severe infectious disease, such as infective endocarditis. We present the first report of infectious arthritis caused by methicillin-sensitive S. lugdunensis after intra-articular hyaluronic acid injection in an immunocompromised patient in Korea.
Arthritis, Infectious*
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Arthritis, Rheumatoid*
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Communicable Diseases
;
Diabetes Mellitus*
;
Endocarditis
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Humans
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Hyaluronic Acid*
;
Immunocompromised Host
;
Korea
;
Osteoarthritis
;
Skin
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Staphylococcus lugdunensis*
;
Staphylococcus*
8.The Association between Stress Level in Daily Life and Age at Natural Menopause in Korean Women: Outcomes of the Korean National Health and Nutrition Examination Survey in 2010-2012.
Byoung O CHOI ; Yeon Ji LEE ; Ji Ho CHOI ; Se Wook CHO ; Hyun Jung IM ; Jee Eun AN
Korean Journal of Family Medicine 2015;36(6):305-309
BACKGROUND: Although several risk factors associated with reduced age at natural menopause (ANM) have been investigated, the results are inconsistent. Excessive stress, which leads to elevation of stress hormones, can also negatively affect reproductive ability, including by accelerating menopause. However, a direct association between stress level and ANM has not yet been demonstrated. Therefore, the object of this study was to investigate the association between stress level and ANM in Korean women. METHODS: Study participants were Korean women between 40 and 70 years old who were in natural menopause during the 5th Korean National Health and Nutrition Examination Survey (n=3,176). The level of stress in daily life was estimated based on data from the mental health topics of the survey. We used the t-test and one-way analysis of variance to analyze the correlation between stress level and ANM. Regression (beta) coefficients calculated by multiple regression analysis were used to estimate various factors affecting ANM. RESULTS: Women who experienced a high level of stress in daily life had a lower mean ANM than women with a low stress level (50.17+/-3.7 and 50.58+/-3.5 years, respectively), with a statistically significant correlation (P<0.05). This correlation was still observed after adjusting for age, body mass index, menstrual regularity, and personal income (P<0.05 for variables). CONCLUSION: In Korean women between 40 and 70 years of age who are in natural menopause, there is a statistically significant correlation between stress level and ANM. In particular, women who experience a high level of stress in daily life have reduced ANM.
Body Mass Index
;
Female
;
Humans
;
Menopause*
;
Mental Health
;
Nutrition Surveys*
;
Risk Factors
9.Analysis of Judicial Precedents on Drug Eruption in South Korea
Yoon Jin CHOI ; Kyeng Wook KIM ; Ji Yeon BYUN ; You Won CHOI ; Joo Young ROH ; Hae Young CHOI
Korean Journal of Dermatology 2023;61(3):162-169
Background:
Both medicolegal disputes and the incidence of cutaneous drug eruptions are increasing in Korea. We were unable to find research that surveyed the legal disputes involving drug eruption cases.
Objective:
This study investigates medical litigation associated with drug eruption cases in Korea.
Methods:
Judicial precedents on drug eruption cases were searched using the Supreme Court of South Korea’s Written Judgement Management System. General characteristics, results, suspected agents, and recognized negligence were analyzed.
Results:
From the search results, 50 cases were selected. Of these, 34 cases had severe cutaneous adverse reactions, including Stevens-Johnson syndrome/toxic epidermal necrolysis (n=25, 50.0%), and drug rash with eosinophilia and systemic symptoms syndrome (n=9, 18.0%). Antimicrobial agents (n=17, 34.0%), non-steroidal anti-inflammatory drugs (n=6, 12.0%), and anticonvulsants (n=6, 12.0%) were the most common drugs implicated. Death was reported in 15 patients (30.0%). In this sample, 22 cases (47.0%) were awarded to the plaintiff, and violation of the duty to inform patients of risks was the most common legal issue cited.
Conclusion
Clinicians should be aware of and advise patients of the potential for severe adverse reactions that can lead to negative outcomes and medicolegal disputes.
10.Dysfunction of the Left Dorsolateral Prefrontal Cortex is Primarily Responsible for Impaired Attentional Processing in Schizophrenia.
Jee Wook CHOI ; Bum Seok JEONG ; Ji Woong KIM
Psychiatry Investigation 2008;5(1):52-59
OBJECTIVE: The results for finding the deficit in the anterior cingulate (ACC) in schizophrenic patients (SZ) have been inconsistent according to the studies that used different Stroop tasks, which is unlike the deficit in the dorsolateral prefrontal cortex (DLPFC). In order to explore for the core region that's responsible for the selective attention deficit in SZ, we examined the results of a functional neuroimaging study, which involved the performance of the Stroop task using high or low prefrontal cortex related loads in SZ. METHODS: Ten schizophrenic patients and healthy controls (HC) received functional magnetic resonance imaging (fMRI) during a Short/Long-term latency Stroop task. The changes in the neural activity were determined in well-known Stroop related regions of interest (ROIs) that consisted of the DLPFC, ACC, the parietal lobule and in the whole brain regions for both the main and interaction effects of latency, and the results of the short-term and long-term latency Stroop conditions were compared. RESULTS: The response times for both the congruency and latency effects were more prolonged in the schizophrenics than in the HC. For the congruency effect, the schizophrenics showed significantly less activation in the same site of the left DLPFC in both the short-term and long-term latency conditions, as compared with the HC. For the latency effect, the regions of the left-side language network were over- or under-activated in the schizophrenics, as compared with the HC. Any interaction effect was not found for both the behavioral and fMRI results. CONCLUSION: Our results indicate that the deficit in the left DLPFC is the core impairment of attentional processing in schizophrenics, regardless of other possible interactions such as the latency effect.
Brain
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Functional Neuroimaging
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Humans
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Magnetic Resonance Imaging
;
Prefrontal Cortex*
;
Rabeprazole
;
Reaction Time
;
Schizophrenia*