1.Treatment of Humeral Shaft Fractures with Seidel Nail.
Hyung Ku YOON ; Ho Seung JEON ; Key Nam CHO ; Ji Ung YANG
The Journal of the Korean Orthopaedic Association 1998;33(3):674-680
Seidel nail provides more advantages for treatment of humeral shaft fracture than other treatment modalities. It enables patients to get high bone union rate, makes surgical technigne less invasive, and allows early mobilization mobilization so that the patients is subjected to more comfortable treatment. But, Seidel nail is apt to injure the rotator cuff and has relatively weak holding power of distal fragment of fracture so that it may result in distraction and rotatory instability, and make nonunion and impaired shoulder function. Thus, in order to the functional and radiological results, complications and technical problems, we evaluated the efficacy of Seidel nail in treatment of 20 cases of hurneral shaft fractures from March l994 to March 1996, retrospectively. The results were as follows. 1. 18 cases(90%) achieved radiological union. 2. The time of union was 12.5 weeks in average. 3. 17 cases achieved satisfactory results according to Neers functional score. 4. The complications included proximal protrusion of nail from the entry site(10%), fracture of greater tuberosity of proximal humerus(5%), loosening of distal spreading screw(10%), and nonunion( l 0%). In conclusion, Seidel nailing is one of good treatment modalities for humeral shaft fracture, but skillful operative technique is needed to obtain the satisfactory functional result. And also, it is necessory to modify the distal locking system of Seidel nail to reinforce the rotational stahility of the fracture site.
Early Ambulation
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Humans
;
Humerus
;
Retrospective Studies
;
Rotator Cuff
;
Shoulder
2.Early MRI Finding of Femoral Head in Traumatic Hip Dislocation.
Hyung Ku YOON ; Kwang Pyo JEON ; Dae Eun JUNG ; Hoe Seung JEON ; Ji Ung YANG
The Journal of the Korean Orthopaedic Association 1997;32(3):565-572
Traumatic dislocation of the hip presents serious problems that may lead to avascular necrosis, nerve palsy, post-traumatic arthritis even when reduction is promptly and adequately carried out. Among them avascular necrosis is the most important prognostic factor, so the early detection of this complication has critical significance for final result. Bone scan has been considered one of early diagnostic test, but recently MRI replaced its role for imaging in the detection of early AVN, treatment monitoring and prediction of prognosis. Authors prospectively studied the early finding of MRI to detect avascular necrosis of the femoral head and to predict prognosis in traumatic hip dislocation and fracture-dislocation. From December 1990 to November 1994, 12 case of dislocation and fracture-dislocation of the hip were studied . In follow up period ranging from 19 months to 65 months, 10 case had excellent or good result. All cases had abnormal MRI finding such as paraarticular edema, capsular bulging, joint effusion, femoral head fracture, but findings such as femoral head signal changes were dectected in only 3 cases. Among the 3 cases, 1 case had developed AVN and 2 cases were uneventful. Other complications were 3 cases of posttraumatic arthritis, 2 cases of incomplete sciatic nerve palsy, and 1 case of heterotrophic ossification. Although early MRI finding at posttrauma 2weeks gave less specific information, it could give good information for risk group and follow up control with more cases. Although it is expensive, MRI can be one of the most reliable reference in early diagnosis of AVN and prediction of prognosis in traumatic dislocation and fracture- dislocation of the hip with non-invasive method.
Arthritis
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Diagnostic Tests, Routine
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Dislocations
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Early Diagnosis
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Edema
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Follow-Up Studies
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Head*
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Hip Dislocation*
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Hip Joint
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Hip*
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Joints
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Magnetic Resonance Imaging*
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Necrosis
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Paralysis
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Prognosis
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Prospective Studies
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Sciatic Neuropathy
3.Manganese-Enhanced MRI Reveals Brain Circuits Associated with Olfactory Fear Conditioning by Nasal Delivery of Manganese
Ji-ung YANG ; Yongmin CHANG ; Taekwan LEE
Investigative Magnetic Resonance Imaging 2022;26(2):96-103
Purpose:
The survival of organisms critically depends on avoidance responses to lifethreatening stimuli. Information about dangerous situations needs to be remembered to produce defensive behavior. To investigate underlying brain regions to process information of danger, manganese-enhanced MRI (MEMRI) was used in olfactory fear-conditioned rats.
Materials and Methods:
Fear conditioning was conducted in male Sprague-Dawley rats. The animals received nasal injections of manganese chloride solution to monitor brain activation for olfactory information processing. Twenty-four hours after manganese injection, rats were exposed to electric foot shocks with odor cue for one hour. Control rats were exposed to the same odor cue without foot shocks. Fortyeight hours after the conditioning, rats were anesthetized and their brains were scanned with 9.4T MRI. Acquired images were processed and statistical analyses were performed using AFNI.
Results:
Manganese injection enhanced brain areas involved in olfactory information pathways in T1 weighted images. Rats that received foot shocks showed higher brain activation in the central nucleus of the amygdala, septum, primary motor cortex, and preoptic area. In contrast, control rats displayed greater signals in the orbital cortex and nucleus accumbens.
Conclusion
Nasal delivery of manganese solution enhanced olfactory signal pathways in rats. Odor cue paired with foot shocks activated amygdala, the central brain region in fear, and related brain circuits. Use of MEMRI in fear conditioning provides a reliable monitoring technique of brain activation for fear learning.
4.Medial Meniscal Root Repair Using Curved Guide and Soft Suture Anchor.
Su Keon LEE ; Bong Seok YANG ; Byeong Mun PARK ; Ji Ung YEOM ; Ji Hyeon KIM ; Jeong Seok YU
Clinics in Orthopedic Surgery 2018;10(1):111-115
Medial meniscal root tears have been repaired using various methods. Arthroscopic all-inside repair using a suture anchor is one of the popular methods. However, insertion of the suture anchor into the proper position at the posterior root of the medial meniscus is technically difficult. Some methods have been reported to facilitate suture anchor insertion through a high posteromedial portal, a posterior trans-septal portal, or a medial quadriceptal portal. Nevertheless, many surgeons still have difficulty during anchor insertion. We introduce a technical tip for easy suture anchor insertion using a 25° curved guide and a soft suture anchor through a routine posteromedial portal.
Menisci, Tibial
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Surgeons
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Suture Anchors*
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Sutures*
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Tears
5.A Case of Rectal Endometriosis Which is Confirmed Colonoscopic Biopsy.
Soo Young CHOI ; Tae Hun LEE ; Tae Gwan LEE ; Sung Uk YANG ; Ji Young KIM ; Byung Goo KIM ; Yong Woo CHOI ; Yong Ung LEE
Korean Journal of Gastrointestinal Endoscopy 1995;15(2):303-309
Endometriosis of the rectum is unusual condition, since it represents an invasion of previously normal bowel by hormone-dependent nonmalignant cell from uterus of the same patient. It is estimated that the incidence of endometriosis is about 8-15% of reproductive women, of whom 3-34% show intestinal invasion of rectosigmoid colon, appendix, ileum, and cecum in order of decreasing frequency. Symptoms related bowel involvement may vary from none to complete intestinal obstruction. Because the mucosa is involved infrequently there is rarely rectal bleeding. X-ray and sigmoidoscopic studies are usually negative. It was not reported that colonic endometriosis was confirmed by endoscopic biopsy. Recently we experienced a case of rectal endometriosis which presented itself as a cyclic rectal bleeding with abdominal pain and diagnosed by colonoscopic biopsy.
Abdominal Pain
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Appendix
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Biopsy*
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Cecum
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Colon
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Colonoscopy
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Endometriosis*
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Female
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Hemorrhage
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Humans
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Ileum
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Incidence
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Intestinal Obstruction
;
Mucous Membrane
;
Rectum
;
Uterus
6.The Results of Proximal Femoral Nail for Intertrochanteric Fracture in Hemodialysis Patient.
Kyung Sub SONG ; Sang Phil YOON ; Su Keon LEE ; Seung Hwan LEE ; Bong Seok YANG ; Byeong Mun PARK ; Ick Hwan YANG ; Beom Seok LEE ; Ji Ung YEOM
Hip & Pelvis 2017;29(1):54-61
PURPOSE: Hip fractures in hemodialysis patients are accompanied by high rates of complications and morbidities. Previous studies have mainly reported on nonunion and avascular necrosis of femoral neck fractures in this patient group. In this study the complication and clinical results of hemodialysis patients with intertrochanteric fractures treated with proximal femoral intramedullary nailing have been investigated through comparison with patients with normal kidney function. MATERIALS AND METHODS: Forty-seven patients were included; the hemodialysis group (n=17) and the control group with normal kidney function (n=30). The medical history and clinical findings including preoperative and postoperative blood examinations, radiological examinations and ambulatory status (measured using the Koval score). The rate of complications and morbidities were also investigated and compared. RESULTS: Preoperative hemoglobin/hematocrit was lower but a significant increase in partial thromboplastin time was observed in the hemodialysis group. The amount of bleeding/transfusions were higher and operative time was longer in the hemodialysis group. Upon radiologic examination, there was no significant difference in rate of unstable fracture and nonunion between the two groups. However the postoperative Koval score was significantly worse and the odds ratio of inability to walk after surgery was 13.5 times higher in the hemodialysis group. CONCLUSION: There was no significant difference in radiological results, but the risk of inability to walk after surgery was 13.5 times higher in the hemodialysis group. Hemodialysis patients have more morbidities and are hemodynamically unstable therefore require special attention. Accurate reduction and firm fixation is required and attentive postoperative rehabilitation is needed.
Femoral Neck Fractures
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Femur
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Fracture Fixation, Intramedullary
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Hip Fractures
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Humans
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Kidney
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Necrosis
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Odds Ratio
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Operative Time
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Partial Thromboplastin Time
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Rehabilitation
;
Renal Dialysis*
7.A Case of Successful Endoscopic Therapy in Iatrogenic Perforation of the Colon during Colonoscopy.
Jai Gyu LEE ; Jin Woong CHO ; Paul KIM ; Ji Eun LEE ; Jin Gyu LEE ; Sung Min LIM ; In Seok SEO ; Yang Ho KIM ; Yong Ung LEE
Korean Journal of Gastrointestinal Endoscopy 2004;29(4):213-216
Colonoscopy is a safe and standard procedure for diagnosis and therapy of colonic disorders. Iatrogenic colonic perforation during diagnostic colonoscopy, a rare abdominal emergency, has an 0.3~0.8% incidence rate. The choice of treatment for this complication remains controversial. Prompt operative intervention is preferred to minimize morbidity and mortality. However, operative intervention is invasive and needs a long-term recovery period. Conservative treatment is less invasive but can lead to more extensive surgery in case of treatment failure. Very important point on the treatment of iatrogenic perforation of the colon during diagnostic colonoscopy is to avoid the leaking of intestinal contents into the intraperitoneal cavity. We report here a case in which an iatrogenic perforation of the colon during diagnostic colonoscopy was successfully treated by endoscopic clip therapy.
Colon*
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Colonoscopy*
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Diagnosis
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Emergencies
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Gastrointestinal Contents
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Incidence
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Mortality
;
Treatment Failure
8.Blood Lead Level as a Predictor of Coronary Artery Disease.
Ryoung Jin PARK ; Seung Hyun KIM ; Ji Ung PARK ; Yang Hyun KIM ; Myoung Bo KIM ; Won Ju PARK ; Jai Dong MOON
Korean Journal of Occupational and Environmental Medicine 2009;21(1):38-45
OBJECTIVES: Lead exposure is known to be associated with high blood pressure, hypertension, coronary artery disease, peripheral arterial disease, left ventricular hypertropy, and electrocardiographic abnormalities. We investigated the association between blood lead and coronary artery calcification and stenosis. METHODS: Between April 2006 and July 2007, 502 adults (345 males and 157 females), who had no history of cardiovascular disease or occupational exposure to lead, were recruited as study subjects. All subjects underwent coronary CT angiography and blood lead measurement. RESULTS: Blood lead levels were distributed from 0.43 to 11.30 (microgram/dL with a geometric mean blood lead level of 2.98+/-1.5 (microgram/dL. The geometric mean blood lead levels were higher in men than women (3.31+/-1.5 (microgram/dL vs. 2.36+/-1.5 (microgram/dL, P < 0.01). Based on a multivariate analysis, a 1 unit ((microgram/dL) increase in blood lead level was associated with a 1.09 (95% confidence interval, 0.92~1.29) and a 1.01 fold (95% confidence interval, 0.63~1.63) greater risk for coronary artery calcification in men and women, respectively. Similarly, a 1 unit (microgram/dL) increase in blood lead level was associated with a 1.25 (95% confidence interval, 1.03~1.51) and a 1.42 fold (95% confidence interval, 0.73~2.75) greater risk for coronary artery stenosis in men and women, respectively. CONCLUSIONS: The results suggest that increased blood lead levels are associated with an increased risk of coronary artery stenosis.
Adult
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Angiography
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Cardiovascular Diseases
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Coronary Artery Disease
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Coronary Stenosis
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Coronary Vessels
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Electrocardiography
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Female
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Humans
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Hypertension
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Male
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Multivariate Analysis
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Occupational Exposure
;
Peripheral Arterial Disease
9.A Study on the Association between Blood Lead Levels and Habitual Tobacco and Alcohol Use in Koreans with No Occupational Lead Exposure.
Ji Ung PARK ; Se Won OH ; Seung Hyun KIM ; Yang Hyun KIM ; Ryoung Jin PARK ; Jai Dong MOON
Korean Journal of Occupational and Environmental Medicine 2008;20(3):165-173
OBJECTIVES: The purpose of this study was to estimate the normal blood lead (PbB) levels in a group of Korean subjects and to evaluate the association between PbB levels and habitual tobacco and alcohol use. METHODS: We recruited 532 adults (320 males and 212 females) with no history of occupational exposure to lead, as study subjects. RESULTS: PbB levels ranged between 0.43 microgram/dl and 9.45 microgram/dl. The adjusted geometric mean PbB in men was 3.19 microgram/dl, which was significantly higher than that seen in women: 2.66 microgram/dl (P=0.017). Geometric mean PbBs were not significantly different between urban and rural patients. The adjusted geometric mean PbB in smokers was 3.31 microgram/dl, which was significantly higher than that seen in nonsmokers: 2.64 microgram/dl (P=0.035). The adjusted geometric mean PbB in drinkers was 3.10 microgram/dl, which was significantly higher than that seen in non-drinkers: 2.75 microgram/dl (P=0.049). CONCLUSIONS: The PbB levels of some Korean adults seem to be comparable to those seen in foreign countries. Our results suggest that tobacco and alcohol cessation will be helpful in decreasing the harmful effect of lead.
Adult
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Drinking
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Humans
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Male
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Occupational Exposure
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Smoking
;
Tobacco
10.Can Silent Ischemic Cerebral Lesions Affect Cognition of Parkinson's Disease Dementia?.
Il Ung KANG ; In Uk SONG ; Soo Jin LEE ; Young Do KIM ; Hyun Ji CHO ; Sung Woo CHUNG ; Youngsoon YANG
Dementia and Neurocognitive Disorders 2013;12(3):72-77
BACKGROUND: Several studies have shown that the presence of cerebrovascular lesions may play an important role for determining the severity of the clinical symptoms of dementia. But no study to date has explored the clinical effect of cerebrovascular disease in Parkinson's disease with dementia (PDD), although cerebrovascular disease is common causes of dementia in elderly population. Therefore we conducted this study to evaluate the relationship between silent cerebrovascular lesions and cognitive decline in PDD. METHODS: Only 27 patients with PDD were chosen; 17 patients had PDD with silent cerebral ischemic lesions (PDDI) and 10 patients had PDD without silent cerebral ischemic lesions (pure PDD). These subjects received the global cognitive function testing and were all evaluated with detailed neuropsychological tests including attention, memory, language, and also the visuospatial and frontal function. RESULTS: There were no significant differences between pure PDD and PDDI group on general cognitive functions tests. Regard to mean time duration of suffering from Parkinson motor symptoms and motor function scale, pure PDD group showed more long duration than PDDI group but there was no significant difference between two groups. Furthermore, there were not any significant differences between the two groups on detailed neuropsychological tests. CONCLUSIONS: We concluded that silent cerebrovascular lesions do not contribute to neuropsychological severity of PDD, although vascular disease is a common cause of cognitive impairment in the elderly. Thus the results of the present study suggest that factors other than cerebrovascular disease contribute to severity of PDD.
Aged
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Cognition
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Dementia
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Humans
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Memory
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Neuropsychological Tests
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Parkinson Disease
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Stress, Psychological
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Vascular Diseases