1.A Clinical Study of Retinopathy of Prematurity.
Jong Won LEE ; Jin Kyung JUNG ; Ji Hee KANG ; Ghee Young JUNG ; Moo Ung KIM
Journal of the Korean Pediatric Society 1994;37(5):636-641
Among 666 premature infants or low birthweight infants who were admitted in NICU of St. Francisco General Hospital from January 1990 to Jun 1992, 96 infants were diagnosed as retinopathy of prematurity by indirect ophthalmoscope. The result were follows: 1) Among 666 patients, retinopathy of prematurity developed in 96 patients(14.1%) 2) The high incidence was observed in low birthweight and small gestational age. 3) Mean age of first diagnosing time was 42.0( 12 day of life and mean gestational age was 31.8 2.5 weeks and mean birthweight was 1646.5 (350.7gm. 4) In gestational age, birthweight and duration of oxygen therapy, there was statistically difference between cryotherapy group and spontaneous regression group. Other possible risk factors-hyaline membrane disease, apnea, anemia-were showed higher incidence in cryotherapy group. 5) Among the 20 infants who were treated with cryotherapy, 16 infants (80%) showed regression of neovascularization.
Apnea
;
Cryotherapy
;
Gestational Age
;
Hospitals, General
;
Humans
;
Incidence
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Membranes
;
Ophthalmoscopes
;
Oxygen
;
Retinopathy of Prematurity*
2.Early MRI Finding of Femoral Head in Traumatic Hip Dislocation.
Hyung Ku YOON ; Kwang Pyo JEON ; Dae Eun JUNG ; Hoe Seung JEON ; Ji Ung YANG
The Journal of the Korean Orthopaedic Association 1997;32(3):565-572
Traumatic dislocation of the hip presents serious problems that may lead to avascular necrosis, nerve palsy, post-traumatic arthritis even when reduction is promptly and adequately carried out. Among them avascular necrosis is the most important prognostic factor, so the early detection of this complication has critical significance for final result. Bone scan has been considered one of early diagnostic test, but recently MRI replaced its role for imaging in the detection of early AVN, treatment monitoring and prediction of prognosis. Authors prospectively studied the early finding of MRI to detect avascular necrosis of the femoral head and to predict prognosis in traumatic hip dislocation and fracture-dislocation. From December 1990 to November 1994, 12 case of dislocation and fracture-dislocation of the hip were studied . In follow up period ranging from 19 months to 65 months, 10 case had excellent or good result. All cases had abnormal MRI finding such as paraarticular edema, capsular bulging, joint effusion, femoral head fracture, but findings such as femoral head signal changes were dectected in only 3 cases. Among the 3 cases, 1 case had developed AVN and 2 cases were uneventful. Other complications were 3 cases of posttraumatic arthritis, 2 cases of incomplete sciatic nerve palsy, and 1 case of heterotrophic ossification. Although early MRI finding at posttrauma 2weeks gave less specific information, it could give good information for risk group and follow up control with more cases. Although it is expensive, MRI can be one of the most reliable reference in early diagnosis of AVN and prediction of prognosis in traumatic dislocation and fracture- dislocation of the hip with non-invasive method.
Arthritis
;
Diagnostic Tests, Routine
;
Dislocations
;
Early Diagnosis
;
Edema
;
Follow-Up Studies
;
Head*
;
Hip Dislocation*
;
Hip Joint
;
Hip*
;
Joints
;
Magnetic Resonance Imaging*
;
Necrosis
;
Paralysis
;
Prognosis
;
Prospective Studies
;
Sciatic Neuropathy
3.Differential diagnoses of magnetic resonance imaging for suspected acute appendicitis in pregnant patients
Jung Yong JI ; Na Ung JI ; Han Kuk SANG ; Choi Cho PIL ; LEE Hee JANG ; Shin Hyuk DONG
World Journal of Emergency Medicine 2018;9(1):26-32
BACKGROUND:Accurate and timely diagnosis of acute surgical disease in pregnant patient is chal enging. Although magnetic resonance imaging (MRI) is the most accurate modality to diagnose acute appendicitis in pregnant patients, it is often used as a last resort because of high cost and long scan time. We performed this study to analyze differential diagnoses of appendix MRI and to investigate if there are any blood tests that can predict surgical condition in pregnant patients. METHODS:A retrospective, cross-sectional study was conducted on 46 pregnant patients who underwent non-enhanced appendix MRI in suspicion of acute appendicitis from 2010 to 2016. Differential diagnoses of appendix MRI were analyzed and blood tests were compared between those who had surgical and non-surgical disease. RESULTS:Appendix MRI differentiated two surgical disease; acute appendicitis and ovarian torsion; and various non-surgical conditions such as uterine myoma, hydronephrosis, ureterolithiasis and diverticulitis among clinically suspected acute appendicitis in pregnancy. The diagnostic accuracy of MRI for acute appendicitis in this study was 93.5%. Patients who had surgical disease showed significantly higher WBC count (≥11,000/mm3), proportion of neutrophils in the WBC (≥79.9%), neutrophil-to-lymphocyte ratio (NLR≥6.4), levels of C-reactive protein (CRP≥1.82 mg/dL) and bilirubin (≥0.66 mg/dL ) than those who had non-surgical disease. CONCLUSION:MRI can reliably differentiate surgical conditions and several blood tests (WBC, proportion of neutrophils in the WBC, NLR, CRP, bilirubin) can help anticipate acute surgical condition among pregnant patients suspected to have acute appendicitis.
4.Outbreaks of mumps: an observational study over two decades in a single hospital in Korea.
Ji Ung RYU ; Eun Kyung KIM ; You Sook YOUN ; Jung Woo RHIM ; Kyung Yil LEE
Korean Journal of Pediatrics 2014;57(9):396-402
PURPOSE: The introduction of the mumps vaccine has dramatically reduced the number of mumps cases, but outbreaks have recently occurred among highly vaccinated populations in developed countries. Epidemiological and clinical characteristics of patients with mumps admitted between 1989 and 2012 in a single hospital in Korea are described in the present study. METHODS: We retrospectively evaluated inpatients with mumps between 1989 and 2012 and outpatients and inpatients with mumps in 2011-2012. RESULTS: A total of 152 patients with mumps were admitted between 1989 and 2012, and 163 patients were recorded in 2011-2012. The highest number of admitted cases occurred in 1998 and 2012 (35 and 34 cases, respectively). Among the patients admitted in 2011-2012, the highest frequency was observed among people aged 15-19 years, and low frequency was observed in those aged <4 years and >20 years, compatible to the city data and national data. In patients admitted to our department in 1998 (35 cases) and in 2010-2012 (27 cases), there were significant differences in the mean age and the rate of secondary measles-mumps-rubella (MMR) vaccination, but had similar clinical features, including complications, except aseptic meningitis. Antimumps immunoglobulin (Ig) G was positive in 83% and 100%, and IgM was positive in 67% and 41%, respectively, in the two periods. CONCLUSION: In Korea, recent mumps outbreaks have occurred mainly among secondary school students who received two doses of the MMR vaccine. The vaccinees might have a modified immune reaction to viral insults, manifesting modified epidemiological and clinical features.
Antibodies
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Developed Countries
;
Disease Outbreaks*
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Humans
;
Immunoglobulin M
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Immunoglobulins
;
Inpatients
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Korea
;
Measles-Mumps-Rubella Vaccine
;
Meningitis, Aseptic
;
Mumps Vaccine
;
Mumps*
;
Observational Study*
;
Outpatients
;
Retrospective Studies
;
Vaccination
5.Dissolution behavior and early bone apposition of calcium phosphate-coated machined implants.
Ji Wan HWANG ; Eun Ung LEE ; Jung Seok LEE ; Ui Won JUNG ; In Seop LEE ; Seong Ho CHOI
Journal of Periodontal & Implant Science 2013;43(6):291-300
PURPOSE: Calcium phosphate (CaP)-coated implants promote osseointegration and survival rate. The aim of this study was to (1) analyze the dissolution behavior of the residual CaP particles of removed implants and (2) evaluate bone apposition of CaP-coated machined surface implants at the early healing phase. METHODS: Mandibular premolars were extracted from five dogs. After eight weeks, the implants were placed according to drilling protocols: a nonmobile implant (NI) group and rotational implant (RI) group. For CaP dissolution behavior analysis, 8 implants were removed after 0, 1, 2, and 4 weeks. The surface morphology and deposition of the coatings were observed. For bone apposition analysis, block sections were obtained after 1-, 2-, and 4-week healing periods and the specimens were analyzed. RESULTS: Calcium and phosphorus were detected in the implants that were removed immediately after insertion, and the other implants were composed mainly of titanium. There were no notable differences between the NI and RI groups in terms of the healing process. The bone-to-implant contact and bone density in the RI group showed a remarkable increase after 2 weeks of healing. CONCLUSIONS: It can be speculated that the CaP coating dissolves early in the healing phase and chemically induces early bone formation regardless of the primary stability.
Animals
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Bicuspid
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Bone Density
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Calcium*
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Dental Implantation
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Dogs
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Osseointegration
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Osteogenesis
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Phosphorus
;
Survival Rate
;
Titanium
6.Is There a Difference in the Effect of Thrombolytic Therapy according to the Presence of Diffusion-Weighted Imaging (DWI)-Fluid Attenuated Inversion Recovery (FLAIR) Mismatching in Patients with Acute Ischemic Stroke?.
Jong Yeong JEONG ; Sang Kuk HAN ; Dong Hyuk SHIN ; Ji Ung NA ; Hyun Jung LEE ; Pil Cho CHOI ; Jeong Hun LEE
Journal of the Korean Society of Emergency Medicine 2015;26(3):225-231
PURPOSE: We performed this study to investigate whether there is difference in the effect of intravenous (IV) thrombolysis according to the presence of diffusion-weighted imaging- fluid-attenuated inversion recovery (DWI-FLAIR) mismatch among acute ischemic stroke patients who visited the emergency department (ED) within 3 hours from the onset of symptom. METHODS: Among ED patients presenting with an acute ischemic stroke between January 2011 and May 2013, those who underwent MRI and received IV thrombolytic therapy were included in this retrospective study. Patients were divided into DWI-FLAIR mismatch and match groups and compared for their initial NIHSS (National Institutes of Health Stroke Scale), NIHSS 24-hour after the thrombolytic therapy, NIHSS on discharge, early neurologic improvement (ENI), and major neurologic improvement (MNI). RESULTS: During study period, 50 patients were finally included among 213 acute ischemic stroke patients. DWI-FLAIR mismatch group showed significantly more reduction in NIHSS 24-hour after the thrombolytic therapy and NIHSS on discharge than the match group (5.5 vs. 1.2, p<0.001, 6.0 vs. 2.3, p<0.01, respectively). Moreover, ENI and MNI occurred significantly more in DWI-FLAIR mismatch group than match group (27/36 vs. 2/14, p<0.001, 12/36 vs. 0/14, p=0.012, respectively). CONCLUSION: Among acute ischemic stroke patients who visited ED within 3 hours from the onset of symptom, those patients who had DWI-FLAIR mismatch on MRI showed significantly better response to IV thrombolytic therapy than DWI-FLAIR match group in terms of neurologic outcome.
Academies and Institutes
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Brain Infarction
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Emergency Service, Hospital
;
Humans
;
Magnetic Resonance Imaging
;
Retrospective Studies
;
Stroke*
;
Thrombolytic Therapy*
7.A Case of Fibrolipoma of the Colon.
Young Jae LEE ; Jin Woong CHO ; Gum Mo JUNG ; Ji Woong KIM ; Yong Keun CHO ; Myoung Jin JU ; Yong Ung LEE
Korean Journal of Gastrointestinal Endoscopy 2008;37(2):142-145
Lipomas of the gastrointestinal tract are rare, and most of them are frequently seen in the colon. This tumor is classified into subtypes by the proportion of the inner mesenchymal components. Fibrolipoma, as a variant type of lipoma, is rich in the fibrous component. It is generally detected incidentally, but sometimes symptoms such as bleeding, abdominal pain or anemia can be observed according to the size, shape and location of the tumor. It can be resected surgically or endoscopically, and then it can be confirmed by the pathologic diagnosis. Recurrence can occur, so follow-up evaluation is needed. We report here on a case of a fibrolipoma of the colon, and the tumor was endoscopically resected.
Abdominal Pain
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Anemia
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Colon
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Follow-Up Studies
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Gastrointestinal Tract
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Hemorrhage
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Lipoma
;
Recurrence
8.The Correlation between Infection Probability Score and Procalcitonin in Emergency Department Patients.
Gyu Dong JO ; Pil Cho CHOI ; Sang Kuk HAN ; Dong Hyuk SHIN ; Hyun Jung LEE ; Ji Ung NA
Journal of the Korean Society of Emergency Medicine 2013;24(6):694-701
PURPOSE: Procalcitonin is a well-established biochemical marker for bacterial infection. We conducted this study to analyze the correlation between procalcitonin and Infection Probability Score (IPS), a recently introduced scoring system to predict bacterial infection in intensive care unit patients. The cutoff value of IPS corresponding to procalcitonin cutoff values was determined for procalcitonin-guided antibiotic therapy in emergency department (ED) patients. METHODS: A retrospective observation study was conducted on adult ED patients who simultaneously underwent an IPS-required blood test and procalcitonin treatment from January 1, 2012 to June 30, 2012. Based on their diagnosis at discharge, patients were grouped into a lower respiratory infection group or an "other" diagnosis group. The correlation between IPS and procalcitonin was analyzed by correlation and linear regression analysis. The IPS value corresponded to 0.25 ng/mL procalcitonin (in the lower respiratory infection group) and 0.5 ng/mL (in the other diagnosis group) as inferred by ROC curve analysis. A total of 722 cases (lower respiratory infection group: 258, other diagnosis group: 464) were included in the final analysis. RESULTS: In correlation analysis, the IPS showed a significant correlation with procalcitonin level in both groups (r=0.26, p<0.01, r=0.25, p<0.01, respectively). In ROC curve analysis, IPS 14 could predict procalcitonin> or =0.25 microg/L in the lower respiratory infection group (area under curve: 0.783 [95% CI, 0.724-0.841], sensitivity: 77.8%, specificity: 72.3%). Also, IPS 14 could predict procalcitonin> or =0.5 microg/L in the other diagnosis group (area under curve: 0.764 [95% CI, 0.717-0.810], sensitivity: 70.1%, specificity: 74.2%). CONCLUSION: The IPS had a significant correlation with procalcitonin level and IPS> or =14 corresponded to the procalcitonin cut-off value to predict bacterial infection in ED patients. Thus, IPS> or =14 may be used to predict bacterial infection and can guide early anti-microbial therapy in ED patients when procalcitonin is not readily available.
Adult
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Bacterial Infections
;
Biomarkers
;
Diagnosis
;
Emergencies*
;
Hematologic Tests
;
Humans
;
Intensive Care Units
;
Linear Models
;
Predictive Value of Tests
;
Retrospective Studies
;
ROC Curve
;
Sensitivity and Specificity
9.Correction of Asymmetric Crying Facies with Botulinum Toxin A Injection: A Case Report.
Seong Oh PARK ; Min Ho KIM ; Jung Yoon SONG ; Ji Ung PARK ; Byung Min YUN ; Tae Hyun CHOI ; Sukwha KIM
Journal of the Korean Cleft Palate-Craniofacial Association 2011;12(2):125-128
PURPOSE: Asymmetric crying facies is caused by agenesis or hypoplasia of the depressor anguli oris muscle and is often associated various anomalies. Several static and dynamic surgical interventions have been reported, but their effects are unreliable. We report on the successful use of botulinum toxin A in an asymmetric crying facies patient. METHODS: A 4-year-old girl presented with a facial asymmetry on crying or smiling. Physical examination revealed that her face had no asymmetry at rest. However, the patient showed characteristic asymmetry when smiling, crying, and with other normal facial movements. Asymmetric crying facies was clinically suspected and the weakness of left depressor anguli oris was present on electrophysiology study. Fifteen units of botulinum toxin type A were injected to the right depressor anguli oris muscle. RESULTS: The patient showed the prominent improvement in the facial symmetry without significant complication and the effect persisted until 3 months post injection. CONCLUSION: Asymmetric crying facies was treated successfully with botulinum toxin A and this method was easy and noninvasive.
Botulinum Toxins
;
Botulinum Toxins, Type A
;
Crying
;
Electrophysiology
;
Facial Asymmetry
;
Facial Paralysis
;
Facies
;
Humans
;
Muscles
;
Physical Examination
;
Preschool Child
;
Smiling
10.The Effect of Counting Numbers out for Giving Breaths on the Interrupting Time and Fraction of Chest Compressions in 2-rescuer Cardiopulmonary Resuscitation: A Manikin Pilot Study.
Hyun Chul YEO ; Hyun Jung LEE ; Ji Ung NA ; Dong Hyuk SHIN ; Sang Kuk HAN ; Pil Cho CHOI ; Jeong Hun LEE ; Jun Seok SEO
Journal of the Korean Society of Emergency Medicine 2015;26(6):557-562
PURPOSE: The aim of this study was to estimate the effect of counting numbers out for giving breaths on the interruption time (IT) of chest compressions (CCs) and chest compression fraction (CCF) in the 2-rescuer cardiopulmonary resuscitation (CPR). METHODS: Thirty medical students were enrolled in this randomized control simulation study, and were randomly divided into the control group and the study group. Both groups performed 2-rescuer CPR for 5-cycles with giving breaths using a bag-mask. Only participants in the study group were instructed to count numbers out for each breath verbally ("one, two") at the end point of each inspiration period and immediately perform CCs at the point of counting "two". RESULTS: However, no differences in terms of depth, rate, incorrect location, and duty cycle of CCs, as well as ventilation volume of each breath, time to delivery of two breaths, and counts of breathing during 1 minute were observed between the two groups. CONCLUSION: The study group had significantly shorter IT and higher CCF compared with the control group. And no significant differences in the other measured parameters of CPR quality were observed between the two groups.
Cardiopulmonary Resuscitation*
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Heart Massage
;
Humans
;
Manikins*
;
Pilot Projects*
;
Respiration
;
Respiration, Artificial
;
Students, Medical
;
Thorax*
;
Ventilation