1.THE DETECTION OF AFP mRNA IN PERIPHERAL BLOOD AND ITS CLINICAL SIGNIFICANCE
Ji CAO ; Liuliang QIN ; Jianjia SU ; Yuan LI ; Nanwu YANG ; Kechen BAN ; Chao OU ; Qinguo Mo
Cancer Research and Clinic 2000;0(06):-
Objective:To search the marker of micrometastatic hepatocellular carcinoma (HCC).Methods:Peripheral blood samples were obtained from 65 patients with hepatocellular carcinoma,21 non HCC malignant tumors,22 chronic hepatitis B or cirrhosis,and 21 normal healthy volunteers.To identify hepatocellular carcinoma cells in peripheral blood, liver specific alpha fetoprotein(AFP)mRNA was amplified from total RNA extracted from whole blood by nested reverse transcription polymerase chain reaction (Nested RT PCR).Results:AFP mRNA was not detected in the normal healthy volunteers and patients with non HCC malignant tumors.The presence of AFP mRNA in patients with HCC(44/65,67.7%)was higher than those with chronic hepatitis B or cirrhosis(2/22,9.1%, P
2.Mauriac Syndrome in a Patient with Type I Diabetes Mellitus.
Ji Yeoun KANG ; Pil Soon YANG ; Hyung Su KIM ; Ok Young KIM ; Chul Hoi KOO ; Wha Mo LEE
Journal of the Korean Pediatric Society 2000;43(6):837-841
Mauriac syndrome consists of a triad of poorly controlled diabetes, profound growth retardation and hepatomegaly. We experienced a case of Mauriac syndrome in an 18-year-old girl who had poorly controlled diabetes mellitus, short stature, hepatomegaly and central obesity. Also at the time of examination, she had complications of diabetic cataract and nephropathy. Fourteen years prior to admission, she was diagnosed as diabetes mellitus at a hospital. Thereafter, she had been managed with irregular insulin injection. On physical examination at admission, her height was 135cm(<3 percentile) and her weight was 39kg(<3 percetile). She was short and obese. The liver was 5 cm palpable below the right subcostal margin. Her sexual maturation was Tanner stage I. On ophthalmologic examination, the cataracts were observed on both eyes and diabetic retinopathy was absent. Diabetic nephropathy could not be confirrned by kidney biopsy due to her mother's refusal. We studied the hormonal, radiographic and histological abnormalities. The hormonal study was normal and the bone age was by delayed as much as 10 years. The liver biopsy revealed glycogen accumulation in hepatocyte. She was consistent with Mauriac syndrome. She was managed by strict diabetic control with insulin therapy, diabetic diet and intensive education. She was discharged with well controlled blood glucose. Five months later, growth acceleration and sexual maturation have not been observed, but hepatomegaly subsided. (J Korean Pediatr Soc 2000;43-837-841)
Acceleration
;
Adolescent
;
Biopsy
;
Blood Glucose
;
Cataract
;
Diabetes Mellitus*
;
Diet, Diabetic
;
Diabetic Nephropathies
;
Diabetic Retinopathy
;
Disulfiram
;
Education
;
Female
;
Glycogen
;
Hepatocytes
;
Hepatomegaly
;
Humans
;
Insulin
;
Kidney
;
Liver
;
Obesity, Abdominal
;
Physical Examination
;
Sexual Maturation
3.A Case of Kasabach-Merritt Syndrome.
Kil Su KIM ; Youn Mo SHON ; Myung Hi SHIN ; Ji Sub OH
Journal of the Korean Pediatric Society 1982;25(3):310-316
We experienced a case of anterior mediastinal teratoma in 26 month old boy with 2 month history of cough and dyspnea. The diagnosis was easily established by chest CAT which revealed calcific densities, while plane radiographs of chest revealed no evidence of calcification. Operation was done with good result and remained in good condition thereafter. A brief review of the related literature was made on this subject.
Anemia
;
Animals
;
Cats
;
Child, Preschool
;
Cough
;
Diagnosis
;
Dyspnea
;
Hemangioma
;
Humans
;
Kasabach-Merritt Syndrome*
;
Male
;
Teratoma
;
Thorax
;
Thrombocytopenia
4.A Case of Mediastinal Teratoma in Early Childhood.
Kil Su KIM ; Youn Mo SHON ; Myung Hi SHIN ; Ji Sub OH
Journal of the Korean Pediatric Society 1982;25(3):305-309
We experienced a case of anterior mediastinal teratoma in 26 month old boy with 2 month history of cough and dyspnea. The diagnosis was easily established by chest CAT which revealed calcific densities, while plane radiographs of chest revealed no evidence of calcification. Operation was done with good result and remained in good condition thereafter. A brief of the related literature was made on this subject.
Animals
;
Cats
;
Child, Preschool
;
Cough
;
Diagnosis
;
Dyspnea
;
Humans
;
Male
;
Teratoma*
;
Thorax
5.A Case of Congenital Mesoblastic Nephroma.
Kil Su KIM ; Youn Mo SOHN ; Myung Hee LEE ; Ji Sub OH ; Ok Ji PAIK
Journal of the Korean Pediatric Society 1982;25(5):503-507
The congenital mesoblastic nephroma is the most common renal neoplasm seen in the first few months of life. This tumor usually benign, but local recurrences and metastases have been reported, and treatment is total nephrectomy. This entity must be differentiated from Wilm's tumor so as to avoid unnecessary postoperative irradiation and chemotherapy. Recently, we experienced a case of congenital mesoblastic nephroma in female newborn infant. Diagnosis was made with physical examination, plain roentgenogram of the abdomen, ultrasonography of the abdomen and I.V.P. and confirmed with microscopic examination. A brief review of the related literature was made on this subject.
Abdomen
;
Diagnosis
;
Drug Therapy
;
Female
;
Humans
;
Infant, Newborn
;
Kidney Neoplasms
;
Neoplasm Metastasis
;
Nephrectomy
;
Nephroma, Mesoblastic*
;
Physical Examination
;
Recurrence
;
Ultrasonography
;
Wilms Tumor
6.A Case of Congenital Mesoblastic Nephroma.
Kil Su KIM ; Youn Mo SOHN ; Myung Hee LEE ; Ji Sub OH ; Ok Ji PAIK
Journal of the Korean Pediatric Society 1982;25(5):503-507
The congenital mesoblastic nephroma is the most common renal neoplasm seen in the first few months of life. This tumor usually benign, but local recurrences and metastases have been reported, and treatment is total nephrectomy. This entity must be differentiated from Wilm's tumor so as to avoid unnecessary postoperative irradiation and chemotherapy. Recently, we experienced a case of congenital mesoblastic nephroma in female newborn infant. Diagnosis was made with physical examination, plain roentgenogram of the abdomen, ultrasonography of the abdomen and I.V.P. and confirmed with microscopic examination. A brief review of the related literature was made on this subject.
Abdomen
;
Diagnosis
;
Drug Therapy
;
Female
;
Humans
;
Infant, Newborn
;
Kidney Neoplasms
;
Neoplasm Metastasis
;
Nephrectomy
;
Nephroma, Mesoblastic*
;
Physical Examination
;
Recurrence
;
Ultrasonography
;
Wilms Tumor
7.Personal Factors and Clinical Learning Environment as Predictors of Nursing Students' Readiness for Practice: A Structural Equation Modeling Analysis
Taewha LEE ; Su Jeong LEE ; Yea Seul YOON ; Hyunju JI ; Sookhee YOON ; SangA LEE ; Yoonjung JI
Asian Nursing Research 2023;17(1):44-52
Purpose:
It is essential to ensure the readiness for practice among undergraduate nursing students since the purpose of such education is to cultivate competent nurses who deliver high-quality and safe nursing. Astin's theory of student involvement suggests that this is affected by their personal factors and learning environment.
Methods:
We conducted a cross-sectional study between November 16, 2020 and December 21, 2020 which examined personal factors and aspects of the clinical learning environment among senior nursing students (n = 838) enrolled across 54 nursing schools in Korea. The participants were asked to fill out a self-administered online survey, which assessed demographic characteristics, self-esteem, depression, work-life balance, clinical learning environment, anxiety during clinical practicum, and readiness for practice. Readiness for practice was measured using the Casey-Fink Readiness for practice survey. We used structural equational modeling to test our hypothetical model.
Results:
The nursing students' readiness for practice was significantly affected by their self-esteem, work-life balance satisfaction, and clinical learning environment. Anxiety during clinical practicum directly influenced their readiness for practice.
Conclusion
Increasing self-esteem and work-life balance satisfaction, and improving their clinical learning environment by providing sufficient educational and clinical support, could help facilitate the transition from nursing schools to real-world practice for nursing students.
8.A Case of Primary Leiomyosarcoma of the Lung.
Jin Woo JUNG ; Kyu Nam LEE ; Kwang Su YOON ; Ji Hong YOO ; Hong Mo KANG
Tuberculosis and Respiratory Diseases 1995;42(4):605-609
Primary leiomyosarcoma of the lung is very uncommon, and fewer than 50 cases now have been reported. Primary leiomyosarcoma of the lung resembles bronchogenic carcinoma in its clinical presentation and radiologic appearance. However, the former has some differences; younger onset than bronchogenic carcinoma, polypoid endobronchial growth, few positive cytologic examination of sputum and unusual lymph node metastasis. We experienced a case of primary leiomyosarcoma of the lung.
Carcinoma, Bronchogenic
;
Leiomyosarcoma*
;
Lung*
;
Lymph Nodes
;
Neoplasm Metastasis
;
Sputum
9.Anti-cariogenic Properties of α-Pinene, a Monoterpene in Plant Essential Oil.
Bog Im PARK ; Yong Ouk YOU ; Ji Su MO ; So Youn AN ; Na Young CHOI ; Kang Ju KIM
International Journal of Oral Biology 2017;42(1):25-31
Dental caries is the most common chronic disease in the dental field. Streptococcus mutans (S. mutans) is the most important bacteria in the formation of dental plaque and dental caries. In a previous study, we confirmed that the essential oil of Chrysanthemum boreale has antibacterial activity against S. mutans. Alpha-pinene is one of the major chemical components of Chrysanthemum boreale essential oil. In the present study, we investigated the inhibitory effects of α-pinene on cariogenic properties such as growth, acid production, biofilm formation, and bactericidal activity on S. mutans. Alpha-pinene at a concentration range of 0.25-0.5 mg/mL significantly inhibited the growth of S. mutans and acid production of S. mutans. Biofilm formation was significantly inhibited at < 0.0625 mg/mL α-pinene, similar to the data from scanning electronic microscopy. Under confocal laser scanning microscopy, the bacterial viability was decreased by α-pinene in a dose-dependent manner. These results suggested that α-pinene may be a useful agent for inhibiting the cariogenic properties of S. mutans.
Bacteria
;
Biofilms
;
Chronic Disease
;
Chrysanthemum
;
Dental Caries
;
Dental Plaque
;
Microbial Viability
;
Microscopy
;
Microscopy, Confocal
;
Plants*
;
Streptococcus mutans
10.Comparison of Physical Activity Level, Physical Activity Pattern and Energy Expenditure in Male and Female Elementary School Soccer Players using Accelerometer and Physical Activity Diary.
Hae Sun AN ; Su Ji CHOI ; Mo Ran LEE ; Jung Sook LEE ; Eun Kyung KIM
Korean Journal of Community Nutrition 2017;22(6):529-542
OBJECTIVES: The purpose of this study was to compare the physical activity level (PAL), the physical activity pattern and the energy expenditure in male and female elementary school soccer players using the accelerometer and the physical activity diary. METHODS: Twenty-five (male 11, female 14) elementary school soccer players (9–12 years) participated in this study. During their daily activities, they wore an accelerometer for seven days (five weekdays and two weekend days) and completed the physical activity diary for three days (two weekdays and one weekend day). PAL was calculated by using the physical activity diary and three equations (Pate Preschool, Freedson Children, and Freedson) were used to calculate the intensity of physical activity and energy expenditure from the counts of accelerometer. RESULTS: The average of physical activity by day of the week, CPM (Counts Per Minute) and METs (Metabolic Equivalents) were significantly higher in males (723.3 ± 149.2 CPM, 2.07 ± 0.18 METs) compared to females (505.6 ± 119.9 CPM, 1.79 ± 0.20 METs), but there was no significant difference in PAEE (Physical Activity Energy Expenditure) between the two groups (males: 15.5 ± 9.1 kcal/day, females: 11.5 ± 6.0 kcal/day). During weekdays, physical activity intensity was significantly higher in males compared to females at lunch time and training time than at other times. In both genders, the PAL was higher during weekdays (males 1.98, females 1.89) compared to weekend (males 1.62, females 1.61) (p<0.05). CONCLUSIONS: Our study observations suggest the necessity to develop an accelerometer equation for accurately evaluating the physical activity of elementary school athletes.
Athletes
;
Child
;
Energy Metabolism*
;
Female*
;
Humans
;
Lunch
;
Male*
;
Motor Activity*
;
Soccer*