1.A case report of insulin autoimmune syndrome in graves' disease.
Kyung Sang LEE ; Ji Hoon KIM ; Woong Hwan CHOI ; Tae Wha KIM ; Mok Hyun KIM
Journal of Korean Society of Endocrinology 1993;8(4):451-455
No abstract available.
Graves Disease*
;
Insulin*
2.A Short-Term In-Vitro Chemosensitivity Test for Ovarian Cancer: Nuclear Damage Assay.
Young Tak KIM ; Kwan Ja JI ; Yong Man KIM ; Joo Hyun NAM ; Jung Eun MOK
Korean Journal of Gynecologic Oncology and Colposcopy 1997;8(1):47-54
No abstract available.
Ovarian Neoplasms*
3.Association between Sleep Quality and Painless Diabetic Peripheral Neuropathy Assessed by Current Perception Threshold in Type 2 Diabetes Mellitus
Dughyun CHOI ; Bo-Yeon KIM ; Chan-Hee JUNG ; Chul-Hee KIM ; Ji-Oh MOK
Diabetes & Metabolism Journal 2021;45(3):358-367
It is known that the painful sensation of diabetic peripheral neuropathy (DPN) results in sleep problems in type 2 diabetes mellitus (T2DM). However, it is not known that the painless DPN also is associated with poor sleep quality in T2DM. The purpose of the current study was to investigate the association between painless DPN and poor sleep quality in T2DM. A total of 146 patients of T2DM who do not have any painful symptoms of DPN were recruited into the study. Among the patients, painless DPN was diagnosed by using the current perception threshold test. Sleep quality was assessed using the Pittsburgh Sleep Quality Index questionnaire. The percentage of painless DPN was significantly higher in the poor sleep quality group than the good sleep quality group (70.0% vs. 35.5%, The current study showed that painless DPN was associated with poor sleep quality. Future studies are required to clarify the pathophysiologic causal relationship between painless DPN and sleep quality.
4.Association between Sleep Quality and Painless Diabetic Peripheral Neuropathy Assessed by Current Perception Threshold in Type 2 Diabetes Mellitus
Dughyun CHOI ; Bo-Yeon KIM ; Chan-Hee JUNG ; Chul-Hee KIM ; Ji-Oh MOK
Diabetes & Metabolism Journal 2021;45(3):358-367
It is known that the painful sensation of diabetic peripheral neuropathy (DPN) results in sleep problems in type 2 diabetes mellitus (T2DM). However, it is not known that the painless DPN also is associated with poor sleep quality in T2DM. The purpose of the current study was to investigate the association between painless DPN and poor sleep quality in T2DM. A total of 146 patients of T2DM who do not have any painful symptoms of DPN were recruited into the study. Among the patients, painless DPN was diagnosed by using the current perception threshold test. Sleep quality was assessed using the Pittsburgh Sleep Quality Index questionnaire. The percentage of painless DPN was significantly higher in the poor sleep quality group than the good sleep quality group (70.0% vs. 35.5%, The current study showed that painless DPN was associated with poor sleep quality. Future studies are required to clarify the pathophysiologic causal relationship between painless DPN and sleep quality.
5.Two Cases of Megaloblastic Anemia Induced by Vitamin B12 Deficiency in Children.
Ji Yoon KIM ; Byoung Mok KIM ; Kun Soo LEE
Korean Journal of Pediatric Hematology-Oncology 2004;11(1):97-101
Megaloblastic anemia induced by Vitamin B12 deficiency is a disorder caused by impaired DNA synthesis. It has been previously thought to be rare in children, however, recent studies suggest that this condition is more common than previously recognized. Deficiency can lead to a wide spectrum of hematologic and neuropsychiatric disorders. Especially in children, it often presents with nonspecific manifestations, such as developmental delay, irritability, weakness, and failure to thrive. Early diagnosis and prompt treatment might resolve these complications, but permanent neurologic damage may have already occurred. We experienced two cases of Megaloblastic Anemia induced by Vitamin B12 deficiency and report them with a brief review of the literature.
Anemia, Megaloblastic*
;
Child*
;
DNA
;
Early Diagnosis
;
Failure to Thrive
;
Humans
;
Megaloblasts*
;
Vitamin B 12 Deficiency*
;
Vitamin B 12*
;
Vitamins*
6.Transgastric Gastroscopic Intra-abdominal Exploration in a Female Dog Model: NOTES (Natural Orifice Transluminal Endoscopic Surgery).
Young Ill KIM ; Jong Heon PARK ; Sang Ill LEE ; Seong Mok JEONG ; Ji Yeon KIM
Journal of the Korean Society of Coloproctology 2007;23(6):397-402
PURPOSE: Natural orifice transluminal endoscopic surgery (NOTES) is a new surgical option using endoscopic advancement to the peritoneal cavity through the stomach, colon, vagina, or urinary bladder without an abdominal wall scar (incision). The aim of this study was to assess the feasibility of transgastric gastroscopic intra-abdominal exploration with gastric incision and closure before the NOTES would be done. METHODS: Under general anesthesia of a female dog, one-channel gastroscope was advanced to the stomach and the lumen was irrigated with anti-bacterial solution. The anterior wall of the antrum was incised by about 1 cm with a needle knife; then, the gastroscope was advanced into the peritoneal cavity. An exploration of the entire intra-abdominal cavity was performed. RESULTS: We were able to evaluate the stomach, the greater omentum, the diaphragm, the peritoneum, the urinary bladder, the bowel, the spleen, the liver, the gallbladder, the uterine horn, the uterine body, and the vagina, but could not evaluate the ovary, the kidney, and the pancreas. The observation of the abdominal cavity was followed by the gastric wall closure with a 135o endoclip. The dog was recovered after confirmation of secure closure of the incision site. CONCLUSIONS: Transgastric incision, closure, and abdominal exploration are feasible without an abdominal wall scar, and the NOTES can be one option for future abdominal operations in humans and needs to be further investigated.
Abdominal Cavity
;
Abdominal Wall
;
Anesthesia, General
;
Animals
;
Cicatrix
;
Colon
;
Diaphragm
;
Dogs*
;
Female*
;
Gallbladder
;
Gastroscopes
;
Horns
;
Humans
;
Kidney
;
Liver
;
Natural Orifice Endoscopic Surgery
;
Needles
;
Omentum
;
Ovary
;
Pancreas
;
Peritoneal Cavity
;
Peritoneum
;
Spleen
;
Stomach
;
Urinary Bladder
;
Vagina
7.Cardiac computed tomography reveals aortic valve perforation in a patient with severe aortic regurgitation.
Namkyun KIM ; Sung Mok KIM ; Sung Ji PARK ; Yeon Hyeon CHOE
The Korean Journal of Internal Medicine 2019;34(1):233-234
No abstract available.
Aortic Valve Insufficiency*
;
Aortic Valve*
;
Humans
8.Prognostic Factor and Survival Benefit of Adjuvant Chemotherapy in Stage IIA Colon Cancer
Mok-Won LEE ; Jin-Su KIM ; Ji-Yeon KIM ; Kyung-ha LEE
Annals of Coloproctology 2021;37(1):35-43
Purpose:
There is no clear evidence of the benefit of adjuvant chemotherapy (AC) in stage IIA colon cancer. Therefore, we aimed to evaluate the prognostic factors and survival benefit of AC in this disease.
Methods:
A retrospective data collection for patients who underwent radical surgery for colon cancer between January 2008 and December 2015 was undertaken. The cohort was divided into the no-AC and AC groups.
Results:
We included 227 patients with stage IIA colon cancer in our study cohort, including 67 and 160 patients in the no-AC and AC groups, respectively. The number of retrieved lymph nodes and the presence of tumor complications as obstruction or perforation were independent risk factors for survival. In the no-AC group, there was a significant difference in survival according to the number of retrieved lymph nodes. In the AC group, there were significant differences in survival according to sidedness and preoperative carcinoembryonic antigen (CEA). There was no significant difference in survival between the no-AC and the AC groups.
Conclusion
The number of retrieved lymph nodes and the presence of tumor complications were prognostic factors for stage IIA colon cancer but lymphovascular and perineural invasion were not. Sidedness and preoperative CEA could be used as factors to predict the benefit of adjuvant chemotherapy. Currently, it is believed that there is no benefit of AC for stage IIA colon cancer. Further studies are needed to determine the survival benefit of adjuvant chemotherapy in stage IIA colon cancer.
9.A case of acardiac twin.
Soo Mee LEE ; Yoon Kyung CHO ; Sang Soon KIM ; Ji Soo HAN ; In Sik LEE ; Joo Hyun NAM ; Jung Eun MOK
Korean Journal of Perinatology 1992;3(2):104-108
10.The outcome of short-term low-dose aspirin treatment in Kawasaki disease based on inflammatory markers.
Jae Won YOO ; Ji Mok KIM ; Hong Ryang KIL
Korean Journal of Pediatrics 2017;60(1):24-29
PURPOSE: Previously, Kawasaki disease (KD) treatment with low-dose aspirin was administered for 6–8 weeks after the acute phase. However, inflammatory marker levels normalize before 6–8 weeks. In this study, we aimed to investigate the clinical outcome of short-term low-dose aspirin treatment based on inflammatory and thrombotic marker levels. METHODS: We performed a retrospective review of the medical records of patients with KD who were hospitalized at Chungnam National University Hospital between September 2012 and May 2014. When fever subsided, low-dose aspirin treatment was started. Inflammatory (white blood cell count, erythrocyte sedimentation rate, and C-reactive protein) and thrombotic markers (D-dimer) were monitored at follow-ups conducted in 1- to 2-week intervals. The low-dose aspirin administration was terminated when both markers were normalized and no cardiovascular complications were observed. RESULTS: Eighty-four patients with KD (complete KD, n=49; incomplete KD, n=35) were enrolled. The inflammatory and thrombotic marker levels were normalized within 3–4 weeks on average. At the beginning the low-dose aspirin treatment, 9 patients had coronary artery lesions but 75 did not. When the low-dose aspirin administration was terminated at the time the inflammatory marker levels were normalized, no new CALs developed during the follow-up at 6–8 weeks. CONCLUSION: Most of the inflammatory marker levels were normalized within 3–4 weeks after the acute phase of KD. New cardiovascular complications did not develop during the course of the short-term aspirin treatment based on the inflammatory marker levels, clinical findings, and echocardiography.
Aspirin*
;
Blood Cell Count
;
Blood Sedimentation
;
Chungcheongnam-do
;
Coronary Vessels
;
Echocardiography
;
Fever
;
Follow-Up Studies
;
Humans
;
Inflammation
;
Medical Records
;
Mucocutaneous Lymph Node Syndrome*
;
Retrospective Studies