1.Research of Solutions to IP Conflict Events in Large-Scale Hospital
Chinese Medical Equipment Journal 1989;0(02):-
Objective To rapidly locate the'illegal' host so as to solve IP conflict events.Methods In combination with the characteristics of large-scale hospital network,SNMP was utilized in network management to rapidly locate the 'illegal' hosts' address when IP conflict occurred.Results The'illegal' IP occupier could be rapidly and effectivly located.Conclusion The IP conflict can be solved efficiently.[Chinese Medical Equipment Journal,2008,29(2):42-44]
2.A case with hereditary fructose intolerance.
Si-jin ZHANG ; Ji WANG ; Lei ZHANG
Chinese Journal of Pediatrics 2006;44(12):957-957
3.Effects of intraperitoneal injection of 5-HT2A receptor antagonist MDL11939 on acute and chronic pain in mice
Siting HUANG ; Ningning JI ; Lei DU ; Gongliang ZHANG ; Yongmei ZHANG
Chinese Pharmacological Bulletin 2017;33(2):223-226,227
Aim To investigate the effects and signifi-cance of 5-HT2A receptor antagonist MDL1 1 939 on a-mice.Methods Kunming male mice were suffered a-cute acetic acid visceral pain,acute incision pain and CCI neuropathic pain.After each animal model was es-tablished,MDL1 1 939 was injected intraperitoneally. The writhing reaction was used to assess acute acetic acid visceral pain,while the thermal withdrawal laten-cy (TWL)was used to evaluate the acute incision pain and CCI neuropathic pain.Results Compared with the control group,MDL1 1 939 (0.25,0.5,1 .0 mg· kg -1 ,i.p.)relieved acetic acid visceral pain signifi-cantly in a dose-dependent manner in mice,as re-vealed by the significant reduction of the number of twisting.In acute incision pain and CCI neuropathic pain,MDL1 1 939 (0.5 mg·kg -1 ,i.p.)significantly increased TWL level.Conclusion 5-HT2A receptor antagonist MDL1 1 939 has analgesic effects on visceral pain,acute pain and neuropathic pain,which might be a novel therapeutic target to treat different pain in clini-cal situations.
5.Stability of Cefoselis Sulfate for Injection in Xylitol Injection
Huaixue JI ; Yan WANG ; Zhumin SHAO ; Lei ZHANG
China Pharmacy 2007;0(35):-
OBJECTIVE:To investigate the stability of cefoselis sulfate for injection in xylitol injection.METHODS:The mixture of cefoselis sulfate for injection and xylitol injection was observed within 6 h after mixing were observed at 25℃ and 37℃ with regard to its appearance,pH value,and UV spectra of cefoselis.The content of cefoselis sulfate in the mixture was determined by UV spectrophotometry.RESULTS:No marked change was noted for the mixture within 6 hours after mixing in terms of the appearance,pH value,ultraviolet absorption spectra and content.CONCLUSION:Cefoselis sulsate for injection is stable within 6 hours after mixing with xylitol injection.
6.Design and Fabrication of a Device for Intraperitoneal Treatment of Pediatric Hernia.
Zehua LEI ; Fengwei GAO ; Pingqian BAO ; Zhixu WANG ; Ji ZHANG
Journal of Biomedical Engineering 2015;32(3):675-679
For treatment of pediatric inguinal hernia, we fabricated a device, i.e. so called "filling type pediatric hernia sac", which treats the problem from the abdominal cavity, through the abdominal and is a self-adaptive closer, using synthetic material. The device includes filling rack, self-adaptive umbrella support bar, bottom piece, outside pulling line and device fixing lines. The filling rack is composed of 2 concentric circles of 3.0 cm diameter with peripherally fixed together and can be pulled into the shapes of a ball or an olive. The supporting bar is structured of 3 pieces with 0.5 cm wide, 4.0 cm long, cross-fixed on top of the filling rack. The bottom piece is in a circular structure with a diameter of 3.0 cm, and it is connected to the filling rack bottom. Adjust positioning stay outside the fixed on the top of the device are connected at one end, and the other end free through filling the top frame connected with the bottom slice of central fixation. By using this device, we treated 37 pediatric inguinal hernia cases with 38 side-inguinal hernia successfully. The mean duration of post-operation follow-ups was 14.6 ± 5.89 months, without hernia recurrence, obvious scar and hard sections of inguinal region. This device could provide a convenient, safe and effective plugging technology for children's pediatric hernia.
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7.Medico-ethical analysis of problems in epileptic population and its impacts on the living quality of patients
Xiaoying ZHENG ; Lei ZHANG ; Ying JI ; Xianghua FAN
Chinese Journal of Tissue Engineering Research 2005;9(32):237-239
OBJECTIVE:To analyze the medico-ethical problems of epilepsy from Medi-ethics and its effect on improving the quality of life of the persons with epilepsy.DATA SOURCES:Articles were computer-searched from Chinese Journal of Medico-ethics, Chinese Journal of Clinical Neurology, Chinese Medical Journal, Chinese Journal of NeuroMed, Chinese Journal of Nerval Mental Disorder from January 1989 to December 2004 with the key words of "epilepsy, medico-ethics and social discrimination". And the language was restricted to Chinese. And we also selected two books, which were Bioethics written by Shen Ming-xian, and The Prevention and Therapy of Epilepsy written by Zhou Zheng-xin for reference.STUDY SELECTION: From all the preliminarily screened papers, 98 papers were obtained related to epidemiology, sociology and ethics.DATA EXTRACTION: Repeated and similar papers were excluded. 10 papers and books were selected from the 98 papers, which touched upon the problems of the epileptics and their life quality. The 10 papers have involved many cross discipline subjects, such as Bioethics, Medico-ethics,and Socio-ethics, which provided more concern about the epileptics from multiple directions.DATA SYNTHESIS: Ethics indicate the principles and guidelines for relationships between people. The ethics explored here refer to normative ethics. Generally, the basic ethical principles are: respect, beneficialness,balance and justice. Since some epileptic patients lack in the knowledge of epilepsy and proper treatment and suffer from discrimination in the health care, more untreated and non-proper treatment, doctors and nursing persons should take the attitude of being beneficial to the patients. Medication for the epileptics, especially the female patients at the first period of pregnancy, the incidence of the deformed children was high. Should the principle of beneficence be applied to mothers or children? The number of the operative treatment was more and more in patients with epilepsy, while surgery itself is a risk behavior .If there is no better method to choose, and all the available choices have their advantage and disadvantages. Physicians can only choose the better one from the two kinds of harm, trying to make the patientssuffer the least harm with the largest effect. Aggressive behaviors can be observed during seizure or unconsciousness state. Controlling the moving range of the patients with epilepsy consciously is in accord with the general ethical behavior, on the contrary, confinement disobeys the morals and the curative effect is not good. The extreme behavior of the patients with epilepsy is suicide and occurred more in unemployed, unmarried and living alone, male, and patients with mental disorders in epilepsy. The direct reasons of suicide are unemployment, low social status, and little understanding and care from their communities, families and friends.The sensible ethical principle for epileptics is to treat the patients as normal people in the society.CONCLUSION: Epileptic crowd need care from the society, family and other factors. Proper considering ethical principle in treating the population is the humane solicitude and to help the patients regain health and improve the life quality.
8.Clinicopathological characteristics of colorectal cancer presenting at young age
Junping LEI ; Guangyan JI ; Jia FU ; Xuan ZHANG ; Zhengqiang WEI
Chongqing Medicine 2015;(32):4517-4518,4521
Objective The aim of this study was to analyse characteristics of CRC in a cohort under the age of 40 .Methods Using single center retrospective cohort study ,we reviewed the prospectively collected database of 2 897 colorectal cancer patients who had undergone curative CRC resections in Chongqing Medical University between 2010 and 2014 .175 patients (5 .8% ) were under 40 ,in which six patients for various reasons (including recurrent colorectal cancer hospital ,incomplete information ,etc .) were excluded .A group of 180 consecutive patients over the age of 40 undergoing surgery for colorectal cancer in the same centre was used as control .Results There had no difference in tumor classification and tumor location between the younger group (<40) and the older group(>40) ,but the lymph node positive rate in younger group was higher ,unable to accurately grasp the preopera‐tive lymph node status ,lead to lack of preoperative staging ,and that made it difficult to preoperative treatment options .Conclusion Therefore ,to young people in colorectal preoperative neoadjuvant chemoradiation indications and the assurance of intraoperative re‐section range ,we need to do more consideration.
9.Investigation on reference values of whole blood trace elements among pregnant women in Hangzhou area
Haibing JI ; Shanshan PAN ; Zhiqun ZHANG ; Lei YU
International Journal of Laboratory Medicine 2016;37(17):2366-2368
Objective To establish the normal reference intervals of whole blood trace elements among pregnant women in Han‐gzhou area to provide the clinical diagnostic basis for ensuring the health of pregnant women and their fetuses .Methods A total of 122 whole blood samples in pregnant awaiting delivery in a general hospital of Hangzhou City during 2015 were collected randomly . The levels of lead(Pb) ,cadmium(Cd) ,copper(Cu) ,zinc(Zn) ,nickel(Ni) ,chromium(Cr) ,beryllium(Be) ,manganese(Mn) ,cobalt (Co) ,arsenic(As) ,molybdenum(Mo) ,thallium(Ti) and thallium(Tl) were determined with ICP‐MS .And the results were statisti‐cally analyzed .Results The detection results of whole blood Cu ,Cr ,Mn and Ti showed a normal distribution .The 5% -95% refer‐ence interval was determined according to x ± 1 .96s ,the normal reference intervals for these 4 elements were 255 .37 -668 .23 , 56 .09-151 .93 ,18 .46-54 .60 and 800 .90 -2 632 .02 μg/L respectively .Conclusion Formulating the normal reference values of whole blood microelements levels has an important significance for clinical doctors to provide the nutritional health care guidance and master the heavy metal pollution level .
10.Chemical Constituents in Blumea Aromatica ( Wall. ) DC
Zhiqiang JI ; Nana TANG ; Jianmin ZHANG ; Lei SHI
China Pharmacist 2015;18(12):2067-2069
Objective:To study the chemical constituents in Blumea aromatica ( Wall. ) DC. Methods:The compounds were iso-lated by silica gel, Sephadex LH-20 column chromatography and TLC. The structures were elucidated by physicochemical properties and spectral analysis. Results:Ten compounds were obtained and elucidated as oleic acid (1), linoleic acid (2), quercetin (3), luteolin (4), naringenin (5), hesperetin (6), gallic acid (7), β-sitosterol (8), daucosterol (9) and hesperidin (10). Conclu-sion:Compounds 1, 2, 5, 6, 7 and 10 are isolated from the plant for the first time.