Lymphomatoid papulosis (LyP) is defined as a histologically malignant, but clinically benign condition. It can appear as erythematous pink to purple papules or nodules. Immunophenotyping studies of the lymphomatoid papulosis lesions have shown a predominance of a CD4 expression and negativity for CD8. However, a positive CD8 expression has rarely been reported for LyP. Herein we report on a case of CD8 positive lymphomatoid papulosis in a 43-year-old man. The patient presented with erythematous, asymptomatic papules on the left axilla and thigh. Histopathologically, there was a wedge-shaped infiltrate composed of a mixture of various cell types, including lymphocytes, histiocytes, neutrophils and large atypical lymphoid cells. Immunophenotyping revealed the neoplastic cells were positive for CD3, CD8 and CD30 and they were negative for CD4, CD20 and CD56.
Adult ; Axilla ; Histiocytes ; Humans ; Immunophenotyping ; Lymphocytes ; Lymphomatoid Papulosis ; Neutrophils ; Thigh

Vibrio cholerae strain other than O1 and O139 (Vibrio cholerae non-O1/O139) are associated with sporadic diarrhea and have often been reported in association with extraintestinal infections. We report a case of peritonitis by V. cholerae non-O1/O139 in 43-year-old male who was diagnosed cirrhosis. He, was complained of abdominal distension and fever without history of consumption of raw sea food and exposure to sea water. Gram negative bacilli were cultured from his peritoneal fluid and identified as V. cholerae sero group O14.
Adult ; Ascitic Fluid ; Cholera ; Diarrhea ; Fever ; Fibrosis ; Humans ; Male ; Peritonitis* ; Seafood ; Seawater ; Vibrio cholerae* ; Vibrio*

Vibrio cholerae strain other than O1 and O139 (Vibrio cholerae non-O1/O139) are associated with sporadic diarrhea and have often been reported in association with extraintestinal infections. We report a case of peritonitis by V. cholerae non-O1/O139 in 43-year-old male who was diagnosed cirrhosis. He, was complained of abdominal distension and fever without history of consumption of raw sea food and exposure to sea water. Gram negative bacilli were cultured from his peritoneal fluid and identified as V. cholerae sero group O14.
Adult ; Ascitic Fluid ; Cholera ; Diarrhea ; Fever ; Fibrosis ; Humans ; Male ; Peritonitis* ; Seafood ; Seawater ; Vibrio cholerae* ; Vibrio*

No abstract available.
Animals ; Horns ; Molluscum Contagiosum

Objectives: ：Self-poisoning is the leading cause of visits to the emergency departments after a suicide attempts. This study is aimed to compare the patient characteristics according to the category of drugs ingested by the patients who attempted suicide. Methods: ：All medical charts were retrospectively reviewed from patients who visited the emergency center, at Seoul Medical Center, due to intentional self-poisoning from April of 2011 to July of 2019. We investigated the information regarding the subtype and quantity of the intoxication drug, how it was obtained, suicidal history, and psychiatric history, as well as, sociodemographic information. Variables were compared between prescription drug (PD) and non-prescription drug (NPD) poisoning groups. Results: ：The mean age of the NPD poisoning group was significantly lower than that of the PD poisoning group. The patient ratio of those enrolled in national health insurance and living with spouses were significantly higher in the NPD poisoning group. Compared to the NPD poisoning group, the PD poisoning group had a higher incidence of mental illnesses, underlying diseases and ratio of involuntary visit to the emergency department.Among the prescription drugs, the benzodiazepine poisoning group had a higher rate of self-prescription than the non-poisoning group, while the zolpidem poisoning group had a higher rate of the using someone else’s prescription than other drugs. Each single drug poisoning group (benzodiazepine, zolpidem, and antidepressant singleagent) had a higher rate of no mental illness than each of the mixed-poisoning group. Conclusions ：Guidelines for regulating non-prescription drugs are needed as a matter of suicide prevention. Also, this study suggests that clinicians need to be careful when issuing prescriptions and should suicidal risk according to patients’ characteristics, duration of follow-up and type of drug packaging.

Objectives: ：Self-poisoning is the leading cause of visits to the emergency departments after a suicide attempts. This study is aimed to compare the patient characteristics according to the category of drugs ingested by the patients who attempted suicide. Methods: ：All medical charts were retrospectively reviewed from patients who visited the emergency center, at Seoul Medical Center, due to intentional self-poisoning from April of 2011 to July of 2019. We investigated the information regarding the subtype and quantity of the intoxication drug, how it was obtained, suicidal history, and psychiatric history, as well as, sociodemographic information. Variables were compared between prescription drug (PD) and non-prescription drug (NPD) poisoning groups. Results: ：The mean age of the NPD poisoning group was significantly lower than that of the PD poisoning group. The patient ratio of those enrolled in national health insurance and living with spouses were significantly higher in the NPD poisoning group. Compared to the NPD poisoning group, the PD poisoning group had a higher incidence of mental illnesses, underlying diseases and ratio of involuntary visit to the emergency department.Among the prescription drugs, the benzodiazepine poisoning group had a higher rate of self-prescription than the non-poisoning group, while the zolpidem poisoning group had a higher rate of the using someone else’s prescription than other drugs. Each single drug poisoning group (benzodiazepine, zolpidem, and antidepressant singleagent) had a higher rate of no mental illness than each of the mixed-poisoning group. Conclusions ：Guidelines for regulating non-prescription drugs are needed as a matter of suicide prevention. Also, this study suggests that clinicians need to be careful when issuing prescriptions and should suicidal risk according to patients’ characteristics, duration of follow-up and type of drug packaging.

No abstract available.
Scrub Typhus*

BACKGROUND: The Immulite 2000 (Diagnostic Products Corp., LA, USA) is a new fully automated chemiluminescent immunoanalyzer. We evaluated the analytical performance of the Immulite 2000. METHODS: We assayed for five tumor markers (alpha-fetoprotein, carcinoembryonic antigen, human chorionic gonadotropin, prostate-pecific antigen, and free prostate-pecific antigen), four reproductive hormones (estradiol, follicle-timulating hormone, luteinizing hormone, and prolactin) and ferritin. Within-un and between-ay precision, linearity, recovery rates, interference, detection limits, comparison with other machines were evaluated. The carry over and hook effct for HCG (human chorionic gonadotropin) were also evaluated. RESULTS: Within-un and between-ay precisions (CVs) were less than 7.0%, 9.1% respectively. The linearity was good for all assays. The recovery rates were also acceptable. No significant analytical interference was caused by hemoglobin (up to 2,000 mg/L), triglyceride (up to 46 mmol/L), and bilirubin (up to 257 micromol/L) for all assays except for estradiol at high concentration of bilirubin. No sample-to-ample carry over was detected. A hook effect was not detected for HCG at the level of 909,000 IU/L. CONCLUSIONS: The Immulite 2000 was shown to have an satisfactory analytical performance for modern layout of the instrument, ease of use, minimal maintenance, as well as the analytical labor efficient productivity of wide variety of analytes. So we concluded that the system was highly suitable for implementation in an automated clinical laboratory.
Bilirubin ; Carcinoembryonic Antigen ; Chorionic Gonadotropin ; Efficiency ; Estradiol ; Ferritins ; Limit of Detection ; Luteinizing Hormone ; Triglycerides ; Biomarkers, Tumor

BACKGROUND: The Immulite 2000 (Diagnostic Products Corp., LA, USA) is a new fully automated chemiluminescent immunoanalyzer. We evaluated the analytical performance of the Immulite 2000. METHODS: We assayed for five tumor markers (alpha-fetoprotein, carcinoembryonic antigen, human chorionic gonadotropin, prostate-pecific antigen, and free prostate-pecific antigen), four reproductive hormones (estradiol, follicle-timulating hormone, luteinizing hormone, and prolactin) and ferritin. Within-un and between-ay precision, linearity, recovery rates, interference, detection limits, comparison with other machines were evaluated. The carry over and hook effct for HCG (human chorionic gonadotropin) were also evaluated. RESULTS: Within-un and between-ay precisions (CVs) were less than 7.0%, 9.1% respectively. The linearity was good for all assays. The recovery rates were also acceptable. No significant analytical interference was caused by hemoglobin (up to 2,000 mg/L), triglyceride (up to 46 mmol/L), and bilirubin (up to 257 micromol/L) for all assays except for estradiol at high concentration of bilirubin. No sample-to-ample carry over was detected. A hook effect was not detected for HCG at the level of 909,000 IU/L. CONCLUSIONS: The Immulite 2000 was shown to have an satisfactory analytical performance for modern layout of the instrument, ease of use, minimal maintenance, as well as the analytical labor efficient productivity of wide variety of analytes. So we concluded that the system was highly suitable for implementation in an automated clinical laboratory.
Bilirubin ; Carcinoembryonic Antigen ; Chorionic Gonadotropin ; Efficiency ; Estradiol ; Ferritins ; Limit of Detection ; Luteinizing Hormone ; Triglycerides ; Biomarkers, Tumor

PURPOSE: We aimed to investigate the correlation between serum cystatin C and clinical manifestations in pediatric patients with urinary tract infections (UTIs). METHODS: We studied 137 patients admitted with UTIs from June 2012 to May 2014. Depending on the presence of renal cortical defects on 99m Tc-dimercaptosuccinic acid scintigraphy, we classified patients into non-renal and renal defect groups. Laboratory and clinical parameters were analyzed, including the levels of serum cystatin C. The correlation between cystatin C and other variables was assessed. RESULTS: Serum cystatin C levels did not differ between the non-renal and renal defect groups. In both groups, serum cystatin C levels increased after 4-5 days of treatment, compared with the level at admission (P<0.001). However, mean levels were within normal ranges. The concentration of serum cystatin C positively correlated with serum creatinine and negatively correlated with age (P<0.05). In contrast, there was no correlation between serum cystatin C and other variables. CONCLUSION: Serum cystatin C does not appear to be a useful biomarker for renal defects in pediatric patients with UTIs. Further studies are necessary to conclude whether serum cystatin C is helpful in predicting deterioration in renal function in pediatric patients with UTIs.
Child* ; Creatinine ; Cystatin C* ; Humans ; Pyelonephritis ; Radionuclide Imaging ; Reference Values ; Urinary Tract Infections*