3.Omega-3 fatty acids and atrial fibrillation
The Korean Journal of Internal Medicine 2023;38(3):282-289
Although some clinical trials have demonstrated reduced incidence of cardiovascular disease with the use of omega-3 fatty acids, others have found an increased risk of atrial fibrillation (AF). AF is the most common sustained cardiac arrhythmia worldwide. It is associated with high morbidity and mortality rates and significant public health burden. Previous studies of the effect of omega-3 fatty acids on AF occurrence have reported contradictory results. Here we reviewed the effect of omega-3 fatty acids on the risk of AF.
4.The Change of Lacrimal Gland Volume in Korean Patients with Thyroid-associated Ophthalmopathy.
Hyoun Do HUH ; Ji Hye KIM ; Seong Jae KIM ; Ji Myong YOO ; Seong Wook SEO
Korean Journal of Ophthalmology 2016;30(5):319-325
PURPOSE: To describe the change of lacrimal gland volumes in Korean patients with thyroid-associated ophthalmopathy (TAO) via computed tomography (CT). METHODS: A retrospective review of CT images from 217 TAO patients and 135 control subjects was performed. The TAO patients were diagnosed between May 2005 and May 2014 and had a CT performed on initial presentation (330 orbital CT scans). These images were compared with 270 orbital CT scans from the control group, obtained between May 2013 and May 2014. An open source DICOM viewer was used to calculate the volume of the lacrimal gland. RESULTS: The mean volume of the lacrimal gland in TAO patients was 0.816 cm³ in the right orbit (standard deviation [SD], 0.048) and 0.811 cm3 in the left orbit (SD, 0.051), with no significant difference between right and left (p = 0.192). However, significant differences were observed between TAO patients and healthy individuals (p < 0.001). There was no significant difference between mean lacrimal gland volumes of males (0.812 cm³; SD, 0.037) and females (0.816 cm³; SD, 0.029) (p = 0.513). There was a negative correlation between gland volume and age in TAO patients (Pearson r = -0.479, p = 0.00). The subjective tearing (right: r = 0.244, p = 0.018; left: r = 0.226, p = 0.024), corneal superficial punctate keratopathy (right: r = 0.192, p = 0.040; left: r = 0.206, p = 0.036), and exophthalmometry (right: r = 0.182, p = 0.032; left: r = 0.180, p = 0.046) correlated with lacrimal gland volume. CONCLUSIONS: This study is the first to use CT images to calculate the lacrimal gland volume of Korean TAO patients. In TAO patients, the lacrimal gland volume was notably increased compared to control subjects. The lacrimal gland volume decreased with age, but there was no difference between gender and no difference between left and right. The lacrimal gland volume correlated with subjective tearing, corneal superficial punctate keratopathy and exophthalmometry.
Computer Communication Networks
;
Female
;
Graves Ophthalmopathy*
;
Humans
;
Lacrimal Apparatus*
;
Male
;
Orbit
;
Retrospective Studies
;
Tears
;
Tomography, X-Ray Computed
;
Troleandomycin
5.Renal infarction caused by paradoxical embolism through a patent foramen ovale.
Hyemin JEONG ; Hyun Woo LEE ; Ji Young JOUNG ; Yoon Young CHO ; Dongmo JE ; Kyungmin HUH ; Hye Ryoun JANG ; Wooseong HUH
Kidney Research and Clinical Practice 2012;31(3):196-199
A 48-year-old man presented with acute right flank pain. A computed tomography scan revealed right renal infarction. Because he had no thrombosis in the renal vessels and no clear embolic source, a further examination was performed to find the cause of the renal infarction. On transesophageal echocardiography, a right-to-left shunt during the Valsalva maneuver established a diagnosis of patent foramen ovale. This is a case of paradoxical embolism through a PFO leading to renal infarction.
Echocardiography, Transesophageal
;
Embolism, Paradoxical
;
Flank Pain
;
Foramen Ovale, Patent
;
Humans
;
Infarction
;
Middle Aged
;
Thrombosis
;
Valsalva Maneuver
6.Colchicine-induced myoneuropathy in a cyclosporine-treated renal transplant recipient.
Kyungmin HUH ; Ji Young JOUNG ; Hyemin JEONG ; Dongmo JE ; Yoon Young CHO ; Hye Ryoun JANG ; Wooseong HUH
Kidney Research and Clinical Practice 2013;32(2):74-77
Colchicine is a relatively safe medication that is widely used for both prevention and treatment of gout attack. However, serious adverse events, includingmyoneuropathy and multiorgan failure, have been reported. We report a case of colchicine-induced myoneuropathy in a female kidney transplant recipient who had been taking cyclosporine. She developed gastrointestinal discomfort and paresthesia 5 days after the initiation of colchicine. She showed signs of myoneuropathy, and hepatic and renal injury. Colchicine toxicity was suspected, and colchicine was discontinued. Her symptoms and laboratory findings improved gradually. Literature was reviewed for previous reports of colchicine-induced myoneuropathy in solid organ transplant recipients.
Colchicine
;
Cyclosporine
;
Female
;
Gout
;
Humans
;
Kidney
;
Paresthesia
;
Transplants
7.The 2016 WHO versus 2008 WHO Criteria for the Diagnosis of Chronic Myelomonocytic Leukemia.
Yeonsook MOON ; Mi Hyang KIM ; Hye Ryoun KIM ; Jeong Yeal AHN ; Jungwon HUH ; Ji Young HUH ; Jae Ho HAN ; Joon Seong PARK ; Sung Ran CHO
Annals of Laboratory Medicine 2018;38(5):481-483
The 2016 WHO diagnostic criteria for chronic myelomonocytic leukemia (CMML) require both absolute and relative monocytosis (≥1×10⁹/L and ≥10% of white blood cell counts) in peripheral blood. Moreover, myeloproliferative neoplasm (MPN) features in bone marrow and/or MPN-associated mutations tend to support MPN with monocytosis rather than CMML. We assessed the impact of the 2016 WHO criteria on CMML diagnosis, compared with the 2008 WHO criteria, through a retrospective review of the medical records of 38 CMML patients diagnosed according to the 2008 WHO classification. Application of the 2016 WHO criteria resulted in the exclusion of three (8%) patients who did not fulfill the relative monocytosis criterion and eight (21%) patients with an MPN-associated mutation. These 11 patients formed the 2016 WHO others group; the remaining 27 formed the 2016 WHO CMML group. The significant difference in the platelet count and monocyte percentage between the two groups indicated that the 2016 WHO criteria lead to a more homogenous and improved definition of CMML compared with the 2008 WHO criteria, which may have led to over-diagnosis of CMML. More widespread use of molecular tests and more sophisticated clinical and morphological evaluations are necessary to diagnose CMML accurately.
Bone Marrow
;
Classification
;
Diagnosis*
;
Humans
;
Leukemia, Myelomonocytic, Chronic*
;
Leukocytes
;
Medical Records
;
Monocytes
;
Platelet Count
;
Retrospective Studies
8.The Effect of Intraoperative Exophthalmometric Values on Enophthalmos Correction in Inferior Orbital Wall Reconstruction.
Yu Jin CHOI ; Ji Hye KIM ; Hyoun Do HUH ; Seong Jae KIM ; Seong Wook SEO
Journal of the Korean Ophthalmological Society 2017;58(7):769-775
PURPOSE: To measure the enophthalmos corrective effect after inferior orbital wall reconstruction, we compared preoperative and intraoperative exophthalmometric values with postoperative exophthalmometric values. METHODS: From January 2014 to April 2016, 60 eyes of 60 patients who underwent surgery for inferior orbital wall fracture were included. In Group 1, the exophthalmometric value was measured before surgery, during the operation, and 6 months after surgery using the Naugle exophthalmometer. In Group 2, the value was measured before surgery and 6 months after surgery using the Hertel exophthalmometer. The thickness of implants was determined by preoperative exophthalmometric values and overcorrection of 0.5 mm was performed in Group 1 patients with relatively large fractures. RESULTS: The mean age of the patients was 32.4 years in Group 1 and 34.3 years in Group 2. The mean duration between injury and surgery was 4.2 weeks in Group 1 and 2.3 weeks in Group 2. There was no statistically significant difference between preoperative exophthalmometric values in Group 1 (−1.78 ± 0.31 mm) and Group 2 (−1.81 ± 0.26 mm), but postoperative exophthalmometric values between Group 1 (−0.25 ± 0.78 mm) and Group 2 (−0.53 ± 0.46 mm) were statistically different (p = 0.034). CONCLUSIONS: The exophthalmometric values and wall fracture size are important factors for determining implant thickness of inferior orbital wall reconstruction. Intraoperative measurement of exophthalmometric values should be considered in inferior orbital wall reconstruction for enophthalmos correction.
Enophthalmos*
;
Humans
;
Orbit*
9.A case of atypical hemolytic uremic syndrome associated with the c.1273C>T mutation in the complement C3 gene.
Hye Jeong CHO ; Jung O KIM ; Ji Young HUH ; Yong PARK ; Myung Gyu KIM ; Doyeun OH
Blood Research 2016;51(3):210-213
No abstract available.
Atypical Hemolytic Uremic Syndrome*
;
Complement C3*
;
Complement System Proteins*
10.Comparative analysis of accuracy of how to use the implant torque controllers.
Lee Ra CHO ; Chan Jin PARK ; Yoon Hyuk HUH ; Ji Hye LEE ; Dae Gon KIM
The Journal of Korean Academy of Prosthodontics 2013;51(4):300-306
PURPOSE: This study was to evaluate the accuracy of how to use the Mechanical Torque-Limiting Devices. MATERIALS AND METHODS: Three different implant manufacturers (Dentium, Osstem, Shinhung) were prepared for each two implant torque controllers. Divided into two groups depending on the method used for removal torque was measured. Repeated measures of ANOVA test (alpha=.05) was used as statistics to evaluate the effect of repeated loading number on the removal torque. Independent t-test was used to evaluate the difference in removal torque of two groups. RESULTS: The removal torque significantly decreased as the number of loading repetition increased (P<.05). There was significant difference between two groups. CONCLUSION: Loosen the handle part of the implant torque controllers spring resilience to recover one group compared to the group that did not, showed a little more closed to the reference value.
Reference Values
;
Torque*