The treatment of patients with severe periodontitis should be proceeded step-bystep through an accurate diagnosis of each patients’ individual tooth and with a strategic treatment plan. Implant-supported fixed prosthetic restoration has the advantage of high patient satisfaction and stable vertical dimension compared to the removable partial denture. However, multiple teeth defect areas lacking hard tissue may be disadvantageous in aesthetic failure and longer treatment time. In addition, it takes a certain period of time to manufacture and install a conventional fixed prosthesis, and during this process, the provisional prosthesis must satisfy the mechanical, biological, and aesthetic requirements of teeth. The purpose of this article is to describe the fabrication of implant-supported fixed prosthesis through a step-by-step approach in a partially edentulous patient.

Background: Robot-assisted laparoscopic radical prostatectomy is an advanced and popular surgical technique. However, increased intracranial pressure which is caused by CO2 pneumoperitoneum and Trendelenburg position is the main cerebrovascular effect. Measurement of optic nerve sheath diameter using ocular ultrasound is a noninvasive and reliable method for the assessment of intracranial pressure. The primary endpoint of this study was to identify whether low blood pressure regulation has any benefit in attenuating an increase of optic nerve sheath diameter during robot-assisted laparoscopic radical prostatectomy. Methods: Optic nerve sheath diameter and cerebral oxygen saturation were measured at baseline (supine position), one and two hours after pneumoperitoneum and Trendelenburg position respectively, and after return to supine position in normal (n = 27) and low blood pressure groups (n = 24). Results: Mean optic nerve sheath diameter values measured at one and two hours after pneumoperitoneum and Trendelenburg position were significantly increased compared to the baseline value (P < 0.001 in normal blood pressure group; P = 0.003 in low blood pressure group). However, the mean optic nerve sheath diameter and cerebral oxygen saturation measured at any of the time points as well as degrees of change between the two groups did not show any significant changes. The peak values of optic nerve sheath diameter in normal and low blood pressure groups demonstrated 14.9% and 9.2% increases, respectively. Conclusions Low blood pressure group demonstrated an effect in maintaining an increase of optic nerve sheath diameter less than 10% during CO2 pneumoperitoneum and Trendelenburg position.

BACKGROUND: Serum eosinophil cationic protein(ECP) level has been proposed as a indirect marker of eosinophilic inflammation of the airway in bronchial asthma. OBJECTIVE: To evaluate serum ECP against indirect clinical markers of disease, we compared bronchial obstruction, bronchial hyperresponsiveness and peripheral blood eosinophil counts, total IgE with serum ECP levels in patients with bronchial asthma and normal controls. METHOD: Fourty-two patients with bronchial asthma and twenty-six normal controls were enrolled. Measurement were made by spirometry, inhalation challenge with methacholine, peripheral blood eosinophil counts, total IgE and FEIA(fluoroenzymatic immunoassay) of serum ECP RESULT: Serum ECP levels were significantly higher in asthmatic patients than normal controls(p<0.0,5). Serum ECP levels were correlated with peripheral blood eosinophil counts(p<0.01, r=0.544) and bronchial hyperresponsiveness(PC,)(p<0.01, r=-0.456) in patients with bronchial asthma. Serum ECP levels were correlated with degree of bronchial obstruction(FEV, % to predicted value, FEV1/FVC%) in total subjects, but not in asthmatic patients. CONCLUSION: Serum ECP level may be used as indicator of disease activity in bronchial asthma and be helpful in differentiation between normal person and asthmatic patients on simple serological method. Further studies on the changes of serum ECP levels according to disease course and therapeutic responses are needed.
Asthma* ; Biomarkers ; Eosinophil Cationic Protein* ; Eosinophils ; Humans ; Immunoglobulin E ; Inflammation ; Inhalation ; Methacholine Chloride ; Spirometry

BACKGROUND: Obtaining a venous blood sample from infants and children can be a painful and traumatic procedure. It has been suggested that capillary blood samples can serve as substitutes for venous blood samples to diagnose anemia. However, few data exist about the correlation between the laboratory results obtained using capillary and venous blood samples. This study was performed to determine if the results from the LC-178CRP(TM) are the same as the results from a conventional hematology analyzer using venous blood. METHODS: After informed consent was obtained, paired venous and capillary blood sample were collected simultaneously from 104 children (M : F=50 : 54). The capillary blood was analyzed using the LC-178CRP(TM), and venous blood was analyzed using an automatic hematology analyzer. The following were compared from capillary and venous samples: CBC, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), red cell distribution width (RDW), and platelet count. The results were analyzed by Pearson's correlation and the Bland Altman Plot method. RESULTS: The hemoglobin values were similar between the two groups of samples and had a high coefficient correlation (r=0.877). White blood cells, hematocrit, MCV, and MCH also had a significant correlation between capillary and venous blood samples. Based on the Bland-Altman method, the agreement between the two methods was considered good. CONCLUSION: The hematologic results from the capillary blood had a close correlation with the conventional venous method, including white blood cell count, and hemoglobin, MCV, and MCH levels. The LC-178CRPtrade mark should be considered as an alternative for venous blood sampling for the tested parameters in children.
Anemia ; Capillaries ; Child ; Erythrocyte Indices ; Glycosaminoglycans ; Hematocrit ; Hematology ; Hemoglobins ; Humans ; Infant ; Informed Consent ; Leukocyte Count ; Leukocytes ; Platelet Count

Temporomandibular Joint (TMJ) dislocation due to tongue cancer operation has a potential risk factor in that it may become a chronic anterior dislocation. In this regard, the treatment methods of TMJ dislocation are more complicated than that of the usual manual reduction therapy. To prevent the reduction procedure from becoming more complicated, clinicians should check the TMJ status afterward the head and neck operations. But, even with caution, chronic dislocation can happen. To restore normal jaw relation in these patients, one can be treated by manual reduction, open surgery under general anesthesia, and by fastening of additional intermaxillary fixations. Here we report two successfully treated cases of TMJ dislocations due to tongue cancer operation, one treated by the conservative method, and the other by the open surgery method.
Anesthesia, General ; Dislocations ; Head ; Humans ; Jaw ; Neck ; Risk Factors ; Temporomandibular Joint ; Tongue ; Tongue Neoplasms

The branchio-oto-renal (BOR) syndrome is a clinically and genetically heterogeneous disease entity which is characterized by the association of preauricular pits, branchial cleft anomaly, hearing loss and various renal anomalies. The incidence of BOR syndrome is approximately 1 : 40,000 and its genetic pattern of transmission is autosomal dominant. Hearing loss is the most common feature of BOR syndrome and is reported in almost 90% of affected individuals. EYA1, the human homologue of the Drosophila eyes absent gene, has been shown to cause BOR syndrome. We report, with a review of literatures, a female patient with BOR syndrome.
Branchial Region ; Branchio-Oto-Renal Syndrome ; Drosophila ; Eye ; Female ; Hearing Loss ; Humans ; Incidence

No abstract available.
Radiation Oncology*

No abstract available.
Herpes Zoster* ; Male ; Penis

Tuberous sclerosis is a rare multisystem syndrome characterized by hamartomatous tumors of the brain, skin, viscera, and eye. The diagnostic triad for this disease, proposed by Vogt, included epilepsy, mental retardation, and adenoma sebaceum. In eyes, retinal hamartomas and optic nerve phacoma are observed over 50% and hypopigmented areas of peripheral retina and iris are often found. We introduce an 18-year old girl with adenoma sebaceum of the face, history of epilepsy and insignificant mental retardation status. She also had a retinal hamartoma in her right eye, optic nerve phacoma in her left eye, shagreen patch on lumbosacral area, angiomyolipoma of both kidneys, periventricular subependymal nodules and calcified cortical nodule of occipital lobe of brain.
Adolescent ; Angiomyolipoma ; Brain ; Epilepsy ; Female ; Hamartoma ; Humans ; Intellectual Disability ; Iris ; Kidney ; Occipital Lobe ; Optic Nerve ; Retina ; Retinaldehyde ; Skin ; Tuberous Sclerosis* ; Viscera

In connective tissue diseases, autoantibodies cause pulmonary interstitial inflammation and fibrosis, and patients require treatment with an immunosuppressive agent such as a steroid. Dermatomyositis is an incurable, uncommon form of connective tissue disease that occasionally causes diffuse pulmonary inflammation leading to acute severe respiratory failure. In such cases, the prognosis is very poor despite treatment with high-dose steroid. In the present case, a 46-year-old man was admitted to our hospital with dyspnea. He was diagnosed with dermatomyositis combined with cryptogenic organizing pneumonia (COP) with respiratory failure and underwent treatment with steroid and an immunosuppressive agent, but the COP was not improved. However, the respiratory failure did improve after treatment with intravenous immunoglobulin, which therefore can be considered a treatment option in cases where steroids and immunosuppressive agents are ineffective.
Autoantibodies ; Connective Tissue Diseases ; Cryptogenic Organizing Pneumonia* ; Dermatomyositis* ; Dyspnea ; Fibrosis ; Humans ; Immunoglobulins* ; Immunosuppressive Agents ; Inflammation ; Lung Diseases, Interstitial ; Middle Aged ; Pneumonia ; Prognosis ; Respiratory Insufficiency ; Steroids