1.A Case of Solitary Circumscribed Neuroma.
Ji Young LEE ; Chun Wook PARK ; Cheol Heon LEE
Annals of Dermatology 2000;12(1):44-47
Solitary circumscribed neuroma is a benign nerve sheath tumor of unknown etiology. Clinically, it appears as a long-standing, solitary, asymptomatic, skin-colored papule or papulonodule. It has been found predominantly on the face in both sexes, mostly in middle age. A 53-year-old female patient visited our department because of a nodule on the side of the distal interphalangeal joint of the left second finger. A biopsy specimen showed a well-circumscribed, partially encapsulated tumor composed of interlacing fascicles of spindle cells. Neither pleomorphism nor mitosis was found. Immunohistochemical stainings for vimentin, neuron specific enolase (NSE) and epithelial membrane antigen (EMA) were positive, but negative for S-100 protein and smooth muscle actin (SMA). We herein report an uncommon case of solitary circumscribed neuroma.
Actins
;
Biopsy
;
Female
;
Fingers
;
Humans
;
Joints
;
Middle Aged
;
Mitosis
;
Mucin-1
;
Muscle, Smooth
;
Neuroma*
;
Phosphopyruvate Hydratase
;
S100 Proteins
;
Vimentin
2.Relationship between Pulmonary Function and Apnea-Hypopnea Index in Asthmatic Children: The Preliminary Study.
Seung Gul KANG ; Heon Jeong LEE ; Seung Hwan LEE ; Young YOO ; Ji Tae CHOUNG ; Leen KIM
Sleep Medicine and Psychophysiology 2009;16(2):74-78
OBJECTIVE: It has been reported that the sleep apnea syndrome in the asthmatic patients is prevalent, however, the systematic study in this field using polysomnography has rarely been performed. The aim of this study is to investigate the relationship between the apnea-hypopnea index (AHI) and the pulmonary function in asthmatic children. METHODS: This study enrolled 19 male and 12 female asthmatic children aged 6-13 years (average 8.2+/-1.7 years old). Complete overnight polysomnography and pulmonary function test were performed for the participants. RESULTS: Of the 31 asthmatic children, 21 (67.7%) met the diagnostic criteria of the pediatric sleep apnea and the average AHI was 1.7+/-1.5/h. The children with higher AHI showed poorer pulmonary function (FEV1/FVC ratio : p=0.002, FEV1%pred : p=0.047). CONCLUSION: These results suggest that the prevalence of the pediatric sleep apnea could be very high among the asthmatic children and the severity of the sleep apnea correlates with the pulmonary function. However, the case-control study to compare the AHI between the asthma and control groups is absolutely necessary because few normative data are available for the children.
Aged
;
Asthma
;
Case-Control Studies
;
Child
;
Female
;
Humans
;
Male
;
Polysomnography
;
Prevalence
;
Respiratory Function Tests
;
Sleep Apnea Syndromes
3.A Case of Prader-Willi Syndrome with Microdeletion of Chromosome 15 q11-q13 Confirmed by FISH.
Ji Heon JANG ; Jee Yeon SONG ; Byung Kyu SUH ; Won Bae LEE ; Byung Churl LEE
Journal of Korean Society of Pediatric Endocrinology 1997;2(1):145-152
Prader-Willi(PW)syndrome is characterized by obesity, hypotonia, mental retardation, hypogonadism, short stature, excessive eating and characteristic facial appearance. Diabetes mellitus has been considered a component of PW syndrome. Recently this syndrome is caused by the absence of paternally derived genes normally located on chromosome segment 15 q11-q13 or may be the result of maternal uniparental disomy with the absence of paternally derived 15 q11-q13 region. The developement of probes containing segments of DNA from chromosome region 15 q11-q13 provides the oppotunity to confirm the diagnosis of PW syndrome by fluorescence in situ hybridization(FISH). We experienced a 15-year-old boy of PW syndrome with diabetes mellitus, who revealed mental retardation, hypogonadism, obesity and microdeletion of chromosome 15 q11-q13 comfirmed by FISH.
Adolescent
;
Chromosomes, Human, Pair 15*
;
Diabetes Mellitus
;
Diagnosis
;
DNA
;
Eating
;
Fluorescence
;
Humans
;
Hypogonadism
;
Intellectual Disability
;
Male
;
Muscle Hypotonia
;
Obesity
;
Prader-Willi Syndrome*
;
Uniparental Disomy
4.A Case of Cefotiam-Induced Contact Urticaria Syndrome.
Kyung Yul SHIN ; Ji Young LEE ; Chun Wook PARK ; Cheol Heon LEE
Korean Journal of Dermatology 1998;36(6):1092-1095
Contact urticaria refers to a wheal-and-flare response occurring on the application of chemicals to intact skin. When contact urticaria is accompanied by systemic symptoms, it is known as the urticaria syndrome. Fourteen cases of cefotiam-induced contact urticaria have been reported in the foreign literature, but no such case, as far as we know, has been described in the Korean dermatology literature. We report a case of contact urticaria syndrome occurring in a 23-year-old nurse due to occupational contact exposure to cefotiam. She experienced generalized urticaria, itching of the skin, difficulty in breathing, and abdominal pain, when she was preparing an injection of cefotiam. An open patch test showed positive reactions to cefotiam, cefmetazole, and ceftriaxone. Since avoiding cefotiam, the symptoms disappeared and did not recurred.
Abdominal Pain
;
Cefmetazole
;
Cefotiam
;
Ceftriaxone
;
Dermatology
;
Humans
;
Patch Tests
;
Pruritus
;
Respiration
;
Skin
;
Urticaria*
;
Young Adult
5.Two Cases of Cefotiam-induced Contact Urticaria Syndrome.
Ji Young LEE ; Gyeong Il KIM ; Chun Wook PARK ; Cheol Heon LEE
Annals of Dermatology 2000;12(2):119-121
Contact urticaria refers to a wheal-and-flare response after cutaneous exposure to certain chemicals. If contact urticaria is accompanied by systemic symptoms, it is referred to as contact urticaria syndrome. Herein we report two cases of contact urticaria syndrome occur-ring in nurses due to occupational exposure to cefotiam.
Cefotiam
;
Occupational Exposure
;
Urticaria*
6.Relationship between Traumatic Spinal Canal Stenotic Ratio and Neurologic Injuries in Thoracolumbar Unstable Fractures
In Heon PARK ; Kee Byoung LEE ; Kyoung Won SONG ; Jin Young LEE ; Ik Ji KIM
The Journal of the Korean Orthopaedic Association 1995;30(6):1631-1637
Several reports on burst fractures of the thoracolumbar spine have noted that the neural canal encroachment caused by bone in the canal did not correlate with the neurologic status of the patient. But in the thoracolumbar spine the average percent compromise was significantly higher in those patients with complete and incomplete lesions, compared with those patients with no neural deficits. In this study, we evaluated 38 patients with unstable thoracolumbar fractures, operated from March 1989 to February 1993 to know the amount of neural canal compromise, demonstrated on computed tomography scans with neurologic status, level of injury and type of fractures. Among them 22 patients had neurologic deficit and 16 did not neurologic deficit. The results were as follows; 1. 19(76%) of 22 patients with disruption of the posterior spinal elements had neurologic defictis. 2. In the group with neurologic deficits, the stenotic ratio was 44% at the epiconus level, 55% at the conus medullaris, level and 63% at the cauda equna level. 3. The average A-P diameter of the bony fragments retropulsed into the spinal canal was 4.5mm at the epiconus level, 5.2mm at the conus medullaris level and 6.0mm at the cauda equina level. 4. Unstable bursting fracture and fracture dislocation showed higher incidence of neurologic injury and percentage of spinal stenotic ratio than those of flexion distraction and wedge compression fracture. In conclusion, the higher the level of the injured vertebrae, the smaller the size of the retropulsed fragment needed compromise the neural tissues. We suggest that it is necessary to get enough decompression for restoration of spinal canal and recovery of neurological function and computed tomography was more sensitive than any other modality in detection the reduction of the retropulsed bony fragment into spinal canal.
Cauda Equina
;
Decompression
;
Dislocations
;
Fractures, Compression
;
Humans
;
Incidence
;
Neural Tube
;
Neurologic Manifestations
;
Spinal Canal
;
Spinal Cord
;
Spine
;
Tomography, X-Ray Computed
7.Lower Serum Cholesterol Level is Associated with More Serious Injury in psychiatric Patients with Suicide Attempt.
Yong Ku KIM ; Heon Jeong LEE ; Ji Yeon KIM ; Min Soo LEE ; So Hyun CHOI
Journal of the Korean Society of Biological Psychiatry 1999;6(2):227-234
An association of low total cholesterol in blood with psychiatric diseases and suicidal behavior has been suggested. As part of an attempt to further explore this relationship, we examine first, whether serum cholesterol levels in psychiatric patients with suicidal attempt would be lower than in non-suicidal psychiatric inpatients or normal controls, second, whether such significant difference of cholesterol levels would be present when the diagnostic groups are analyzed separately, third whether low cholesterol level would be associated with a history of serious suicidal attempts, and finally, whether low cholesterol level in suicide attempters is as state or a trait marker. We determined the serum cholesterol levels in 231 patients admitted to an emergency room following an suicidal attempt, in the same numbers of age-, sex- and diagnosis-matched non-suicidal psychiatric controls, and in the same numbers of age-, sex matched normal controls. The seriousness of an attempt was divided into 5 grades according to the degree of the resulting medical injury. Total cholesterol levels in suicide attempters were significantly lower compared with both psychiatric and normal controls, when sex, age, and nutritional status(i.e., body mass index) were controlled for. This significant relationship was observed in major depressive disorders and personality disorders, but not in schizophrenia and bipolar type I disorders. The severity of suicide by a lowering of blood cholesterol was related to the magnitude of the cholesterol reduction. After treatment of their psychiatric ailments, the cholesterol levels in suicide attempters were significantly increased. This result suggests that low cholesterol level in psychiatric patients might be a potential biological marker of suicide risk. It is hypothesized that low cholesterol levels is associated with the suicide by modifying the serotonin metabolism, the production of interleukin-2 and melatonin metabolism in psychiatric patients.
Biomarkers
;
Cholesterol*
;
Depression
;
Depressive Disorder, Major
;
Emergency Service, Hospital
;
Humans
;
Inpatients
;
Interleukin-2
;
Melatonin
;
Metabolism
;
Personality Disorders
;
Schizophrenia
;
Serotonin
;
Suicide*
8.Erosion of an Inflatable Penile Prosthesis Reservoir into the Bladder, Presenting Bladder Calculi .
Ju Heon YANG ; Ji Sung PARK ; Hyeuk Jun JANG ; Byung Hwa LEE
Korean Journal of Urology 2004;45(10):1077-1079
Complications of penile prosthesis include malfunction, infection and patient dissatisfaction. Herein, a rare complication of a retained reservoir having eroded into the bladder after the removal of the penile components of a three-piece penile prosthesis, is reported. A 39-year-old man complained of irritative voiding symptoms. The symptoms had developed 4 years after the removal of the penile components of the prosthesis. The erosion of the reservoir into the bladder was discovered incidentally during the treatment of bladder calculi. The reservoir was removed by an open vesicolithotomy.
Adult
;
Calculi
;
Cytochrome P-450 CYP1A1
;
Humans
;
Penile Prosthesis*
;
Prostheses and Implants
;
Urinary Bladder Calculi*
;
Urinary Bladder*
9.A Case of Epithelioid Blue Nevus on the Nose.
Su Hyun PARK ; Myeong Heon CHAE ; Ji Yeoun LEE ; Tae Young YOON
Korean Journal of Dermatology 2018;56(4):294-295
No abstract available.
Nevus, Blue*
;
Nose*
10.A Case of Nodular Lichen Sclerosus.
Myeong Heon CHAE ; Jee Yon SHIN ; Ji Yeoun LEE ; Tae Young YOON
Korean Journal of Dermatology 2018;56(5):351-353
No abstract available.
Lichen Sclerosus et Atrophicus*
;
Lichens*