1.Atypical Kawasaki Disease Presenting as Acute Kidney Injury in a Patient with Influenza B Virus Infection.
Ye Jin HAN ; Sung Jin KIM ; Ji Hei CHA ; Seung Joo LEE ; Sejung SOHN
The Ewha Medical Journal 2015;38(2):80-84
Influenza virus infection is a common respiratory disease in children. Renal complications of influenza infection were not commonly encountered until the 2009 H1N1 influenza pandemic, when acute kidney injury (AKI) frequently developed in severely ill patients. Kawasaki disease (KD) is another rare association in pandemic influenza virus infections. There are some reports about KD coincident with influenza A H1N1/09 infection. However, simultaneous AKI and KD in influenza A or B virus infections have never been reported. Herein, we report the first case of influenza B virus infection that initially presented as AKI but was subsequently diagnosed as atypical KD.
Acute Kidney Injury*
;
Child
;
Herpesvirus 1, Cercopithecine
;
Humans
;
Influenza B virus*
;
Influenza, Human
;
Mucocutaneous Lymph Node Syndrome*
;
Orthomyxoviridae
;
Pandemics
2.Changes of Gene Expressions in Spontaneously Hypertensive Rat Model After Losartan Treatment.
Ji Hei CHA ; Hye Ryon LEE ; Kwan Chang KIM ; Min Sun CHO ; Young Mi HONG
Korean Circulation Journal 2012;42(11):761-768
BACKGROUND AND OBJECTIVES: The renin angiotensin system seems to play an important role in the development of cardiac and vascular hypertrophy in hypertension. The changes in pathology, and gene expressions of the angiotensin II receptor type 1A (ATIA) and angiotensin converting enzyme (ACE) were investigated in order to explore the effects of losartan in spontaneously hypertensive rat (SHR) models. MATERIALS AND METHODS: Twelve week-old male Wistar rats were grouped as follows: control (C) group, hypertension (H) group, and losartan (L) group in which SHR was treated with losartan (10 mg/kg/day). Western blot and reverse transcription-polymerase chain reaction analysis regarding seven genes such as endothelin-1, ACE, ATIA, neutrophil cytosolic factor, brain natriuretic peptide, troponin I, endothelial nitric oxide synthase were performed. RESULTS: Systolic blood pressure was significantly decreased in the L group compared with the H group in weeks 3 and 5. ACE and ATIA proteins in the L group were lower than H group in week 5. CONCLUSION: Losartan reduced blood pressure, cardiac hypertrophy and protein expressions of ACE and ATIA. Changes of protein expressions were more sensitive than changes in pathology. Further study is needed for the differing doses of losartan in SHR models.
Blood Pressure
;
Blotting, Western
;
Cardiomegaly
;
Cytosol
;
Endothelin-1
;
Gene Expression
;
Humans
;
Hypertension
;
Hypertrophy
;
Losartan
;
Male
;
Natriuretic Peptide, Brain
;
Neutrophils
;
Nitric Oxide Synthase Type III
;
Peptidyl-Dipeptidase A
;
Proteins
;
Rats, Inbred SHR
;
Rats, Wistar
;
Receptors, Angiotensin
;
Renin-Angiotensin System
;
Troponin I
3.Prevalence of Atopic Dermatitis among Korean Adults Visiting Health Service Center of the Catholic Medical Center in Seoul Metropolitan Area, Korea.
Min Joo KIM ; Tae Wook KANG ; Eun Ah CHO ; Hei Sung KIM ; Jung Ah MIN ; Hoon PARK ; Jin Wou KIM ; Sang Hee CHA ; Young Bok LEE ; Sang Hyun CHO ; Sun Ji KIM ; Jung Eun KIM ; Hyun Jung PARK ; Min Jee CHOI ; Min Ju KANG ; Kyung Ho LEE ; Kwang Hyun CHOI ; Kyung Moon KIM ; Dong Jae KIM ; Young Min PARK
Journal of Korean Medical Science 2010;25(12):1828-1830
The point prevalence of atopic dermatitis (AD) among Korean adults visiting the Health Service Center for health check-ups was assessed. AD was diagnosed based on the questionnaires filled by patients and through physical examination by dermatologists. A total of 3,563 persons completed the questionnaires, and 2,032 persons were examined by the dermatologists. According to the questionnaires, the prevalence of AD was 7.1%, and from the dermatologists' examination, it was 2.6% overall, which decreased with age significantly. The prevalence in men was higher than that of women. Grading the severity of AD according to their eczema area and severity index scores, 70.6% were classified as being mild, 25.5% moderate, and 3.9% severe. Interestingly, concomitance of psoriasis and AD was found in 0.5% of those examined by the dermatologists. Our results suggest that AD is one of the most common skin diseases not only in children but also in adults in Korea.
Adult
;
Age Factors
;
Aged
;
Dermatitis, Atopic/complications/diagnosis/*epidemiology
;
Female
;
Hospitals, University
;
Humans
;
Male
;
Middle Aged
;
Prevalence
;
Psoriasis/complications
;
Questionnaires
;
Republic of Korea/epidemiology
;
Severity of Illness Index
;
Sex Factors