1.Treatment Effect of Tranexamic Acid in Plasma D-dimer Level Elevated Anti-histamine Resistant Chronic Urticaria Patients.
Ji Young JUN ; Ji Hye PARK ; Jong Hee LEE ; Dong Youn LEE ; Joo Heung LEE ; Jun Mo YANG
Korean Journal of Dermatology 2017;55(9):628-629
No abstract available.
Humans
;
Plasma*
;
Tranexamic Acid*
;
Urticaria*
2.A Case of Foreign Body Granuloma after Squalene Injection by Non-dermatologists.
Ju Hee HAN ; Ji Hyun LEE ; Jun Young LEE ; Young Min PARK
Korean Journal of Dermatology 2016;54(8):671-672
No abstract available.
Foreign Bodies*
;
Foreign-Body Reaction
;
Granuloma
;
Granuloma, Foreign-Body*
;
Squalene*
3.Development of a Noble Dosimetry Using Metaphase Analysis and Micronuclei Assay of Bone Marrow Cells in Mice.
Jung Jun MIN ; Hee Seung BOM ; Young Ho KIM ; Hyun Joong YOON ; Ji Yeul KIM
Korean Journal of Nuclear Medicine 2000;34(1):74-81
PURPOSE: The purpose of this study was to develop in vivo dosimetries using both chromosomal aberrations and micronuclei in mice to assess biological effects of radiations. MATERIALS AND METHODS: Five each mice were irradiated with 0, 1, 2, 3, 4, 5, 10 Gy of Cs-137 gamma-rays. We scored numbers of chromosomal aberrations in metaphase spreads and numbers of micronuclei in bone marrow smears under light microscope, and obtained the dose-response relationships. We also examined the relationship between the two dose-response curves. RESULTS: The frequency of both chromosomal aberrations and micronuclei increased with dose, in a linear-quadratic manner. The delta, beta, and alpha coefficients were 0.0176, 0.0324, and 0.0567 for metaphase analysis (r=1.0, p<0.001) and 0.0019, 0.0073, and 0.0506 for micronuclei assay (r=1.0, p<0.001). The frequency of chromosomal aberrations and micronuclei in diffirent radiation doses was significantly correlated (r=0.99, p<0.01). CONCLUSION: In vivo dosimetry using either metaphase analysis or micronucleus assay was feasible in mice. These methods could be useful to evaluate biological effects of radiation.
Animals
;
Bone Marrow Cells*
;
Bone Marrow*
;
Chromosome Aberrations
;
Metaphase*
;
Mice*
;
Micronucleus Tests
4.Nutrition Teachers' Perception of the Importance and Performance Frequency of Their Roles in the Indicators and Items on a Teacher Evaluation.
Journal of the Korean Dietetic Association 2010;16(2):146-159
This study was conducted to determine the appropriateness of the indicators and items on teacher evaluations for professional development and to provide insight for their improvement. To accomplish this, the perception of the importance and performance frequency of 318 nutrition teachers regarding their roles inherent in the indicators and items were evaluated through a survey questionnaire based on a five-point Likert scale. The quantitative data were analyzed using descriptive statistics and a paired t-test. In addition, the reflective analysis and constant comparison method were employed to analyze the responses to the open-ended questions asking problems in the indicators and items. The results revealed that the mean scores for the importance and performance frequency of most indicators and items were over four points, which implies that most indicators and items are appropriate for evaluating the job tasks of nutrition teachers. However, it was suggested that a few items be revised or removed for their improvement and appropriateness. This study concluded that nutrition teachers should have more chances to provide nutrition education for students to enable them to perform as teachers and not simply dietitians.
Humans
;
Surveys and Questionnaires
5.Prognostic Implication of Normal Myocardial Perfusion Scintigraphy in Patients with Chest Pain.
Ji Yeul KIM ; Hee Seung BOM ; Jung Jun MIN ; Ho Cheon SONG
Korean Journal of Nuclear Medicine 1997;31(1):67-72
Myocardial scintigraphy is a widely used noninvasive procedure with high sensitivity for the detection of patients with suspected coronary artery disease. The purpose of this study was to determine the prognostic value of a normal myocardial scintigraphy in 292 patients (150 males, 142 females, mean age 53+/-12 years) with chest pain who were followed from 7 to 58 (mean 25) months. Myocardial SPECT was performed with Tc-99m MIBI in 173 patients, with Tc-99m tetrofosmin in 74 patients and with T1-201 in 45 patients. During the follow-up period, there were 2 cardiac deaths and 2 nonfatal myocardial infarctions resulting in cardiac event rate of 1.37% (0.66% per year). The cardiac event rate was not different in patients with angiographically normal coronary arteries (1/30, 3.3%) and in those who had significant coronary a disease (2/27, 7.4%) (p=0.60). In conclusion, patients with chest pain and normal myocardial scintigraphy have a low cardiac event rate, and there was no significant difference of cardiac event rates between patients with normal and abnormal coronary angiograms.
Chest Pain*
;
Coronary Artery Disease
;
Coronary Vessels
;
Death
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Myocardial Infarction
;
Myocardial Perfusion Imaging
;
Perfusion Imaging*
;
Perfusion*
;
Prognosis
;
Thorax*
;
Tomography, Emission-Computed, Single-Photon
6.Comparison of Stress-rest and Rest-stress One Day Myocardial Perfusion Scintigraphies in Detecting Coronary Artery Diseases.
Ji Yeul KIM ; Hee Seung BOM ; Jung Jun MIN ; Ho Cheon SONG
Korean Journal of Nuclear Medicine 1997;31(1):30-35
It has been shown that both rest and stress myocardial perfusion imagings with technetium agents can be performed on the same day using two different doses injected within few hours. The purpose of this study was to compare the two protocols (stress-rest and rest-stress) in detecting coronary artery diseases. One hundred and sixty patients (101 males, 59 females, mean age 57+/-9 years) and 120 patients (79 males, 41 females, mean age 59+/-10 years) underwent stress-rest myocardial perfusion SPECT and rest-stress myocardial perfusion SPECT, respectively All of them underwent both myocardial perfusion SPECT and coronary angiography within 1 month. A coronary stenosis was considered significant when it compromised the luminal diameter by> or =50%. The chi square test was used to compare differences in sensitivity, specificity and accuracy between the two groups. The overall sensitivity, specificity and accuracy of stress-rest protocol were 99%, 35%and 68%, respectively. Those of rest-stress protocol were 96%, 47%, and 78%, respectively. There was no difference between the two protocols in identifying individual diseased coronary artery branches. Therefore, one day stress-rest and rest-stress myocardial SPECT using Tc-99m agents were comparable and were very sensitive tests in detecting coronary artery diseases.
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Stenosis
;
Coronary Vessels*
;
Female
;
Humans
;
Male
;
Perfusion Imaging
;
Perfusion*
;
Phenobarbital
;
Sensitivity and Specificity
;
Technetium
;
Tomography, Emission-Computed, Single-Photon
7.Efficacy of teicoplanin in gram-positive bacterial infection.
Ji So RYU ; Jun Hee WOO ; Kee Won KIM ; Hyun Tae KIM ; Yong Hun KIM
Korean Journal of Infectious Diseases 1992;24(3):183-189
No abstract available.
Gram-Positive Bacterial Infections*
;
Teicoplanin*
8.A Case of Allergic Contact Cheilitis from Propyl Gallate.
Ji Ho LEE ; Doo Hee YOON ; Jun Young LEE ; Hyung Ok KIM
Korean Journal of Dermatology 1997;35(2):374-378
Propyl gallste and other gallic acid esters are used as antioxidants in lipsticks, lip balms and salves, cosmetic creams and lotions, bakery products, edible fats and other pharmaceutical and industrial products. Propyl gallate is used widely but allergic contact dermatits from propyl gallate is rare. A 44-year-old female patient had pruritic multiple tiny erythematous papules and vesicles on the margin of her lip for a week. We found that the causative material of the allergic contact cheilitis was propyl gallate. We proved it with a patch test, provocation use test and quantitative and qualitative analysis of the lipstick. To our knowledge, this is the first case report of lipstick allergic contact cheilitis from propyl gallate in Korean literature.
Adult
;
Antioxidants
;
Cheilitis*
;
Esters
;
Fats
;
Female
;
Gallic Acid
;
Humans
;
Lip
;
Ointments
;
Patch Tests
;
Propyl Gallate*
9.Helical tomotherapy for spine oligometastases from gastrointestinal malignancies.
Yunseon CHOI ; Jun Won KIM ; Ik Jae LEE ; Hee Ji HAN ; Jonggeal BAEK ; Jinsil SEONG
Radiation Oncology Journal 2011;29(4):219-227
PURPOSE: This study evaluated the treatment effectiveness and proper radiation dose of helical tomotherapy (HT) in spine oligometastases from gastrointestinal cancers. MATERIALS AND METHODS: From 2006 to 2010, 20 gastrointestinal cancer patients were treated with HT for spine oligometastases (31 spine lesions). The gross tumor volume (GTV) was the tumor evident from magnetic resonance imaging images fused with simulation computed tomography images. Clinical target volume (CTV) encompassed involved vertebral bodies or dorsal elements. We assumed that the planning target volume was equal to the CTV. We assessed local control rate after HT for 31 spine metastases. Pain response was scored by using a numeric pain intensity scale (NPIS, from 0 to 10). RESULTS: Spine metastatic lesions were treated with median dose of 40 Gy (range, 24 to 51 Gy) and median 5 Gy per fraction (range, 2.5 to 8 Gy) to GTV with median 8 fractions (range, 3 to 20 fraction). Median biologically equivalent dose (BED, alpha/beta = 10 Gy) was 52 Gy10 (range, 37.5 to 76.8 Gy10) to GTV. Six month local control rate for spine metastasis was 90.3%. Overall infield failure rate was 15% and outfield failure rate was 75%. Most patients showed pain relief after HT (93.8%). Median local recurrence free survival was 3 months. BED over 57 Gy10 and oligometastases were identified as prognostic factors associated with improved local progression free survival (p = 0.012, p = 0.041). CONCLUSION: HT was capable of delivering higher BED to metastatic lesions in close proximity of the spinal cord. Spine metastases from gastrointestinal tumors were sensitive to high dose radiation, and BED (alpha/beta = 10 Gy) higher than 57 Gy10 could improve local control.
Disease-Free Survival
;
Gastrointestinal Neoplasms
;
Humans
;
Magnetic Resonance Imaging
;
Neoplasm Metastasis
;
Radiotherapy, Intensity-Modulated
;
Recurrence
;
Spinal Cord
;
Spine
;
Treatment Outcome
;
Tumor Burden
10.Simultaneous Upper and Lower Eyelid Reconstruction for Eyelid Defects Following a Dog Bite.
Journal of the Korean Ophthalmological Society 2012;53(4):582-587
PURPOSE: While the principles of eyelid reconstruction are well established, the rapid choice of a method of upper and lower eyelid defect reconstruction is difficult. The authors present a successful case of simultaneous reconstruction of upper and lower eyelid defects with a modified paramedian forehead flap resulting from a dog bite. CASE SUMMARY: The authors report a case of a 77-year-old woman with total hyphema and extensive skin defects involving the forehead, cheek, and upper and lower eyelid resulting from a dog bite. The wound on the left periorbital area was treated with microimplantation and skin grafts from the left thigh and groin. In the weeks following, sequential failure of the flap and skin graft was observed, and exposed keratitis worsened, resulting in corneal perforation. Evisceration with hydroxyapatite implantation and paramedian forehead flap was performed. After 3 weeks, division of the pedicle, transverse division of the flap, and socket reconstruction were performed. CONCLUSIONS: Reconstruction of large, full thickness defects of both upper and lower eyelids with a paramedian forehead flap is associated with a good cosmetic outcome. Paramedian forehead flap should be considered as an effective choice for simultaneous upper and lower eyelid reconstruction.
Aged
;
Animals
;
Bites and Stings
;
Cheek
;
Corneal Perforation
;
Cosmetics
;
Dogs
;
Durapatite
;
Eyelids
;
Female
;
Forehead
;
Groin
;
Humans
;
Hyphema
;
Keratitis
;
Skin
;
Thigh
;
Transplants