1.The Change of Cortical Activity Induced by Visual Disgust Stimulus.
Wook JUNG ; Doo Heum PARK ; Jae Hak YU ; Seung Ho RYU ; Ji Hyeon HA ; Byoung Hak SHIN
Sleep Medicine and Psychophysiology 2013;20(2):75-81
OBJECTIVES: There are a lot of studies that analyze the interaction between the emotion of disgust and the functional brain images using fMRI and PET. But studies using sLORETA (standardized low resolution brain electromagnetic tomography) almost do not exist. The aim of this research is to explore the relationship of the emotion of disgust and the cortical activation using sLORETA analysis. METHODS: Forty five healthy young adults (27.1+/-2.6 years) participated in the study. While they were watching 4 neutral images and 4 disgusting images associated with mutilation selected from the international affective picture system (IAPS), participants' EEGs were taken for 30 seconds per one picture. Through these obtained EEG data, sLORETA analysis was performed to compare EEGs associated with neutral and negative images. RESULTS: During looking for visual disgusting stimulus, all participants reported unpleasantness, arousal and stress. In sLORETA analysis, the decrease of current density in theta wave was shown at left frontal superior gyrus (BA10) and middle gyrus (BA10, 11). This voxel cluster consists of a total of 11 voxels and the threshold of t value indicating statistically significant decreases in the current density (p<0.05) was -1.984. There were no differences between male and female in the degree of being disgusted by the stimuli. CONCLUSION: This finding may suggest that the activation of dorsolateral prefrontal cortex might be associated with regulating disgust emotion.
Arousal
;
Brain
;
Electroencephalography
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Magnets
;
Male
;
Prefrontal Cortex
;
Young Adult
2.A study on the clinical manifestation and treatment of ectopic pregnancy.
Man Jae LEE ; Sang Kee PARK ; Woo Kang CHUNG ; Sang No YOO ; Ji Hak JUNG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1514-1526
No abstract available.
Female
;
Pregnancy
;
Pregnancy, Ectopic*
3.The Effect of Platelet-Rich Plasma on Allograft Transplantation after Curettage in Benign Bone Tumor.
Jae Do KIM ; Ji Youn KIM ; Su Jin JANG ; So Hak CHUNG ; Gu Hee JUNG
The Journal of the Korean Bone and Joint Tumor Society 2010;16(1):8-13
PURPOSE: This study was performed to evaluate the efficiency of Platelet-rich plasma (PRP) for acceleration of bone healing process on allograft transplantation after curettage in benign bone tumor. MATERIALS AND METHODS: From December 2007 to February 2009, twenty-one patients who had benign bone tumor and underwent allograft transplantation after curettage were evaluated. Mean follow-up period was 14.6 months (range, 12-26 months). We compared with 13 cases of PRP group and 8 cases of non-PRP group in terms of size of lesion, bone resorption, amount of applied PRP and complications. The mean age at surgery was 23.6 years (range, 4-73 years). The most common diagnosis was simple bone cyst (7) followed by enchondroma (4), giant cell tumor (3), undifferentiated benign bone tumor (3) and so on. RESULTS: The mean size of lesion was 33.5 cm3 (range, 2.3-181.9 cm3) (29.4 cm3 in PRP group and 40.2 cm3 in non-PRP group). The mean volume of injected PRP was 7.4 cc (range, 3-12 cc). Bone union started at 3.0 months (range, 1.5-5.8 months) in PRP group and 5.3 months (range, 4-8 months) in non-PRP group. Three cases for each group were excluded due to recurrence and pathologic fracture. One patient had febrile episode 3 weeks later after surgery which subsided with antibiotics. CONCLUSION: The PRP could accelerate bone union in allograft transplantation after curettage of benign bone tumor. Furthermore, we expect that PRP can accelerate bone union in fracture or non-union.
Acceleration
;
Anti-Bacterial Agents
;
Bone Cysts
;
Bone Resorption
;
Chondroma
;
Curettage
;
Follow-Up Studies
;
Fractures, Spontaneous
;
Giant Cell Tumors
;
Humans
;
Platelet-Rich Plasma
;
Recurrence
;
Transplantation, Homologous
;
Transplants
4.Impact of Solvent Exposure on the Occupational Hearing Loss.
Ji Ho LEE ; Young Ju GO ; Hun LEE ; Jung Hak KANG ; Cheol In YOO ; Choong Ryeol LEE ; Yang Ho KIM
Korean Journal of Occupational and Environmental Medicine 2000;12(4):537-546
OBJECTIVES: This study was to evaluate the impacts of simultaneous exposure to noise and mixed solvents on workers'hearing threshold level (HTL) over five-year period. METHODS: The study was conducted by interview and annual audiometric test on workers in ship building industry from 1994 to 1998. The cases(workers who exposed to noise and mixed solvent simultaneously) were 43 male workers and controls (workers who exposed to nolle) were selected by matching method with regard to age, sex, carrier, and noise exposure level. To assess the impacts of solvent exposure on hearing threshold level, with considering other factors, general liner model was used. RESULTS: 1. The audiogram of all subjects showed typical sensorineural hearing loss pattern. The mean HTLe were increased at high frequency (4000HB and 8000Hz) for study period. 2. The HTLs of cases were more increased than those of controls at high frequencies (4000Hz and 8000Hz), but there was not statlstical significance. 3. The impact of age on the HTL was statistically significant at 250Hz and 500Hz (p(0.05), and the impact of noise on the HTL was statistically significant at 250Hz, 2000Hz and 4000Hz (p(0.05), but the impact solvent exposure on the HTL was not significant. 4. The changes in HTLs of cases were higher than those of controls at high frequency, there were not statistical significance at 4000Hz, but only at 8000Hz (p=0.087). 5. Statistical analysis of the general linear model implicated that the changes in HTL was impacted by noise exposure bevel significantly (p=0.031) and Impacted by solvent exposure weakly (p=0.087) at 8000Hz. CONCLUSIONS: The results of this study suggest that workers who simultaneously exposed to noise and mixed solvent were at risk for more affected HTL than those exposed to noise exposure only, but we could not find definitive evidence. Further detailed studies must be made in large number of workers.
Construction Industry
;
Hearing Loss*
;
Hearing Loss, Sensorineural
;
Hearing*
;
Humans
;
Linear Models
;
Male
;
Noise
;
Ships
;
Solvents
5.Tension-Free Vaginal Tape Operation in Stress Urinary Incontinence: Comparison between Local Versus General Anesthesia Groups.
Korean Journal of Urology 2003;44(1):59-63
PURPOSE: To assess the differences between local and general anesthesia, with the tension-free vaginal tape (TVT) operation, in relation to the clinical outcome, surgical complications and degree of satisfaction of women with stress incontinence. MATERIALS AND METHODS: A nonrandomized, retrospective study was performed on 65 patients having undergone a tension-free vaginal tape operation between April 1999 and June 2001. After explaining the anesthetic procedure to the patients, 35 did not want to be admitted, so chose local anesthesia, with the other 30 choosing general anesthesia. The clinical outcomes of the operation were evaluated by telephone interviews, and the definition of success or failure determined by Stamey's criteria. RESULTS: The mean follow-up periods of the patients with local and general anesthesia were 14.2 (6.1-31.3) and 12.6 (6.4-30.7) months, respectively. The success rates with local and general anesthesia were 94.2 and 96.6%, respectively, with no significant difference between the two groups. The mean post-void residual urine volumes were 51.6 (8-210) and 47.4 (5-180)ml, respectively, and the indwelling periods of the Foley catheter were 1.9 (1.1-12.8) and 2.2 (1.3-11.5) days, respectively. Bladder perforations occurred in 2 patients under local anesthesia and in 3 under general anesthesia, which was cured by an indwelling catheter over a 2 day period. CONCLUSIONS: The TVT procedure was a very effective and safe surgical treatment for female stress urinary incontinence, and there were no differences in the success rates and surgical complications between anesthesia groups. Considering the cost and admission period, local anesthesia may be better than general anesthesia, but a longer-term follow-up will be required.
Anesthesia
;
Anesthesia, General*
;
Anesthesia, Local
;
Catheters
;
Catheters, Indwelling
;
Female
;
Follow-Up Studies
;
Humans
;
Interviews as Topic
;
Retrospective Studies
;
Suburethral Slings*
;
Urinary Bladder
;
Urinary Incontinence*
6.Tension-Free Vaginal Tape Operation in Stress Urinary Incontinence: Comparison between Local Versus General Anesthesia Groups.
Korean Journal of Urology 2003;44(1):59-63
PURPOSE: To assess the differences between local and general anesthesia, with the tension-free vaginal tape (TVT) operation, in relation to the clinical outcome, surgical complications and degree of satisfaction of women with stress incontinence. MATERIALS AND METHODS: A nonrandomized, retrospective study was performed on 65 patients having undergone a tension-free vaginal tape operation between April 1999 and June 2001. After explaining the anesthetic procedure to the patients, 35 did not want to be admitted, so chose local anesthesia, with the other 30 choosing general anesthesia. The clinical outcomes of the operation were evaluated by telephone interviews, and the definition of success or failure determined by Stamey's criteria. RESULTS: The mean follow-up periods of the patients with local and general anesthesia were 14.2 (6.1-31.3) and 12.6 (6.4-30.7) months, respectively. The success rates with local and general anesthesia were 94.2 and 96.6%, respectively, with no significant difference between the two groups. The mean post-void residual urine volumes were 51.6 (8-210) and 47.4 (5-180)ml, respectively, and the indwelling periods of the Foley catheter were 1.9 (1.1-12.8) and 2.2 (1.3-11.5) days, respectively. Bladder perforations occurred in 2 patients under local anesthesia and in 3 under general anesthesia, which was cured by an indwelling catheter over a 2 day period. CONCLUSIONS: The TVT procedure was a very effective and safe surgical treatment for female stress urinary incontinence, and there were no differences in the success rates and surgical complications between anesthesia groups. Considering the cost and admission period, local anesthesia may be better than general anesthesia, but a longer-term follow-up will be required.
Anesthesia
;
Anesthesia, General*
;
Anesthesia, Local
;
Catheters
;
Catheters, Indwelling
;
Female
;
Follow-Up Studies
;
Humans
;
Interviews as Topic
;
Retrospective Studies
;
Suburethral Slings*
;
Urinary Bladder
;
Urinary Incontinence*
7.CT of head and neck lymphoma.
Moung Sook LEE ; Hong Soo KIM ; Jung Ik JI ; Eun Young JO ; Ju Whan WI ; Hak Song REE
Journal of the Korean Radiological Society 1993;29(6):1151-1157
Lymphoma is the second most common neoplasm in the head and neck, and is the most common cause of unilateral neck mass in patients between 21 and 40 years of age. This report is a retrospective review of histologically proven lymphomas in 42 patients regarding histologic type, clinical stage, and CT imaging patterns. CT imaging plays an important role in making diagnosis, planning treatment, and evaluating recurrence after treatment. CT imaging patterns are classified into 4 types: Type 1 is nodal lymphoma, Type 2 extranodal lymphoma, Type 3 combined nodal and extranodal lymphoma, and Type 4 multifocal extranodal lymphoma. In conclusion, Lymphoma should be considered when multiple, nonnecrotic, homogenous lymph nodes are located in deep lymphatic chains (especially when they are large and bilateral or when both are the superficial and deep lymph node chains are involved simultaneously) and no mucosal abnormality of the aerodigestive tract is observed. Additionary, when a large nasopharyngeal mass lesion shows limited or equivocal bone destruction or a mass is identified on two sides of a nasal bone without frank destruction and when multiple sites of disease are identified in extranodal tissues.
Diagnosis
;
Head*
;
Humans
;
Lymph Nodes
;
Lymphoma*
;
Nasal Bone
;
Neck*
;
Recurrence
;
Retrospective Studies
8.Each Case of Benign and Malignant Mucocele of the Appendix.
Yong Bum PARK ; Ji Soo HAN ; Joo Hak LEE ; Dae Joon CHUN ; Joo Hyun NAM ; Jung Eun MOK
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(3):99-106
Mucocele of the appendix is uncomrnon and rarely diagnosed preoperatively. The malignant rountpart-i.e. mucinous cystadenocarcinoma--has the same grross appearance and many micro scopic features in cornmon wilhe the benign form. It rnay be associated with ovarian mucinous cystadenoma of strikingly similar microscopic appearence. A serious complication is a rupture of the mucoeele resulting in pseudomyxoma peritonei. Each case of benign and malignant mucocelr of the appendix falsely diagnosecl as an oovarian tumor before laparotxumy are presented wilh a brief rieview of the literatures.
Appendix*
;
Cystadenoma, Mucinous
;
Mucins
;
Mucocele*
;
Pseudomyxoma Peritonei
;
Rupture
9.Evaluation of Methods for Fetal Weight Estimates Using Ultrsound Formula at Term.
Mi Hae PARK ; Kyung Jin KIM ; Yun Seok YANG ; In Tak HWANG ; Ji Hak JUNG ; Jun Sook PARK
Korean Journal of Obstetrics and Gynecology 1999;42(8):1744-1750
A total of 150women with singleton pregnancies who were delivered between 37 and 42weeks gestation had ultrasound scans on elective cesarean section day. The biparietal diameter(BPD), head circumference(HC), abdominal circumference(AC) and femur length(FL) were measured in all cases. Equations of estimated fetal body weight(BWT) for Korean term fetuses using AC alone, BPD/AC, AC/FL, HC/AC/FL, BPD/AC/FL, BPD/HC/AC/FL were made by stepwise multiple regression analysis and were compared with foreign equations such as Campbell(AC), Shepard(BPD/AC), Hadlock I(AC/FL), Hadlock II(HC/AC/FL), Hadlock III(BPD/AC/FL), and Hadlock IV(BPD/HC/AC/FL). The results were as follows. 1. The equations of BWT by sonographic measurement were Equation1 (AC) logeBWT=6.105936+0.005957X(AC) (R=0.876) Equation2 (BPD,AC)logeBWT=6.53614548+0.00004963X(ACXBPD) (R=0.929) Equation3 (AC,FL) logeBWT=6.25336442+0.00751602X(FL)+0.00005155X(ACXFL) (R=0.950) Equation4(HC,AC,FL) logeBWT=6.39631346+0.00004823X(ACXFL)+0.00002023X(FLXHC) (R=0.953) Equation5(BPD,AC,FL) logeBWT=5.99934074+0.00871394X(BPD)+0.00005132X(ACXFL) (R=0.960) 2. When BPD, AC and FL were measured, the addition of HC didn,t affected to accuracy of EFW 3. The best results of all equations were obtained with our equation 5(Mean error=2.36gm, Mean absolute error=96.39gm, Mean deviation + SD(%)=0.07+0.37) and among foreign equations, the best results were with Hadlock III equation(Mean error=18.35gm, Mean absolute error=107.82gm, Mean deviation + SD(%)=-0.46+0.42) 4. The equations using AC/FL (our equation 3, Hadlock I) are more accurate than those using BPD/AC (our equatione 2, Shepard) when utilizing two parameters. Therefore, equation using AC/FL is recommended when the BPD is unobtainable at term or labor 5. The percentage of cases in which the EFW was within +5% and +200gm of the actual birth weight was highest at our equation 5 for 82% and 89%, Hadlock IV equation for 79%, 88%. 6. Our equations had relatively an equal tendency to under- and overestimate fetal weight, but foreign equations, especially Campbell and Hadlock II equations tended to underestimate. 7. Analysing according to actual birth weight, our all equations gave the most accurate estimates of fetal weigh for birth weight group between 3000-3499gm, but for birth weight group above 3500gm, that was not. At birthweight group above 3500gm, the equations depend on femur length are more accurate than the equations independ on fumr length.
Birth Weight
;
Cesarean Section
;
Female
;
Femur
;
Fetal Weight*
;
Fetus
;
Head
;
Pregnancy
;
Ultrasonography
10.Incidence of Overactive Bladder in Benign Prostatic Hyperplasia and the Efficacy of Combination Therapy of Alpha Blocker with Tolterodine.
Hyun Woo KIM ; Sung Il SEO ; Jun Sung KO ; Ji Hak JUNG ; Ji Youl LEE
Korean Journal of Urology 2003;44(10):1006-1010
PURPOSE: The incidence of overactive bladder (OAB) and the efficacy of alpha blocker and tolterodine combination therapy were examined in patients with symptomatic benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: Between March 2001 and December 2001, 144 BPH patients were subdivided into those with BPH, or BPH with OAB, based on urodynamic studies. All patients were treated with alpha blockers for 3 months. Patients with no symptomatic improvement were treated with alpha blockers and tolterodine for 2 months. An increase in the International prostate symptom scores (IPSS) of more than 3 points after medication was considered an improvement, but if not, as a failure. RESULTS: Of the 144 patients, 76 (53%) had BPH and 68 (47%) had BPH with OAB. The patients with BPH and OAB were older (p<0.05), but no differences were observed in the serum creatinine, IPSS, prostate volume, maximum flow rate or post-void residual urine (PVR) between the 2 groups. After 3 months treatment with alpha blockers, 79% (60/76) of the BPH and 35% (24/68) of the BPH with OAB patients had improved (p<0.05). Of the patients showing no improvement, 38% (6/16) with BPH and 73% (32/44) with BPH and OAB showed improvement after the addition of tolterodine. CONCLUSIONS: The combination therapy was more effective than alpha blockers alone in the treatment of patients with coexisting BPH and OAB. We recommend identifying these patients with an initial urodynamic study, which allows for the appropriate management and identification of those patients that may benefit from a more invasive treatment.
Creatinine
;
Humans
;
Incidence*
;
Prostate
;
Prostatic Hyperplasia*
;
Urinary Bladder
;
Urinary Bladder, Overactive*
;
Urodynamics
;
Tolterodine Tartrate