1.Industrial low back pain in shipyard workers.
Journal of the Korean Academy of Rehabilitation Medicine 1993;17(2):259-268
No abstract available.
Low Back Pain*
2.The Study of Proliferating Cell Nuclear Antigen in Colorectal Carcinoma.
Ho Soo CHOI ; Bok Soog YANG ; Ji Shin LEE ; Min Cheol LEE
Korean Journal of Pathology 1995;29(3):311-320
The determination of proliferative activity in the colorectal mucosa has been used for different purposes as the estimation of cancer risk and the assessment of disease activity in ulcerative colitis. But the prognostic significance of proliferative activity in colorectal carcinomas remains controversial. To investigate the prognostic significance of proliferative activity in colorectal carcinomas, the author estimated the proliferative activity immunohisto chemically using the monoclonal antibody PCNA and compared with clinicopathological data in 62 colorectal carcinomas. The results were as follows: 1) The reactivity of PCNA was more pronounced at the infiltrative margins of the tumors and tumor cells within the vascular or lymphatic channels. 2) The mean PCNA index of colorectal carcinomas was 40.5?0.4%. PCNA indices had positive correlations with lymph node invasion(p<0.05), liver, metastasis(p<0.05), Dukes' stage(p<0.01) and TNM classification(p<0.01), and didn't correlated with location of tumor, size of tumor, histological type and lymphtic or vascular invasion. 3) The patients with high PCNA index(more than 45%) represented higher recurrence or metastasis rate(37.5%) than those with low PCNA index (less than 45%)(19.3%) in Dukes B or C colorectal carcinomas during the follow-up periods, but not significant statistically. These results suggested that the reactivity of PCNA may be a useful prognostic factors in colorectal carcinomas.
Neoplasm Metastasis
3.A Case of Cefotiam-Induced Contact Urticaria Syndrome.
Kyung Yul SHIN ; Ji Young LEE ; Chun Wook PARK ; Cheol Heon LEE
Korean Journal of Dermatology 1998;36(6):1092-1095
Contact urticaria refers to a wheal-and-flare response occurring on the application of chemicals to intact skin. When contact urticaria is accompanied by systemic symptoms, it is known as the urticaria syndrome. Fourteen cases of cefotiam-induced contact urticaria have been reported in the foreign literature, but no such case, as far as we know, has been described in the Korean dermatology literature. We report a case of contact urticaria syndrome occurring in a 23-year-old nurse due to occupational contact exposure to cefotiam. She experienced generalized urticaria, itching of the skin, difficulty in breathing, and abdominal pain, when she was preparing an injection of cefotiam. An open patch test showed positive reactions to cefotiam, cefmetazole, and ceftriaxone. Since avoiding cefotiam, the symptoms disappeared and did not recurred.
Abdominal Pain
;
Cefmetazole
;
Cefotiam
;
Ceftriaxone
;
Dermatology
;
Humans
;
Patch Tests
;
Pruritus
;
Respiration
;
Skin
;
Urticaria*
;
Young Adult
4.Rehabilitation treatment system for the convalescent and maintenance periods.
Journal of the Korean Medical Association 2017;60(11):870-874
Since rehabilitation treatment does not simply treat a disease, but treats the patient who has a disease, it is not desirable to determine the treatment strategies based soly on the time of onset of a disease. Rehabilitation treatment should involve carefully evaluating the features of the disease and the patient, which requires considerable time. The convalescent (subacute) period requires a system in which rehabilitation treatment for central nervous system diseases can be administered for at least 2 years. In addition, the definitions and details of rehabilitation treatment that can be conducted by a rehabilitation specialist in the convalescent period and those of rehabilitation treatment conducted in the maintenance (chronic) period should be determined in advance, and these steps should be combined with the development of appropriate provisions in the medical insurance system for each period.
Central Nervous System Diseases
;
Humans
;
Insurance
;
Rehabilitation*
;
Specialization
5.Epidermal Growth Factor Receptor Expression and Cell Proliferation in Renal Cell Carcinoma.
Ji Shin LEE ; Jong Jae JUNG ; Min Cheol LEE ; Chang Soo PARK
Korean Journal of Pathology 2000;34(4):273-279
The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein whose expression is a possible cause of increased tumor cell proliferation and has recently been proposed as a prognostic parameter in some tumors. Expression of EGFR was studied immunohistochemically in 62 cases of human renal cell carcinomas to evaluate their possible prognostic roles. We also examined the correlation between EGFR expression and cell proliferation by immunohistochemical staining for proliferating cell nuclear antigen (PCNA). Fifty-six cases (90.3%) expressed EGFR, with staining largely confined to the cell membrane and cytoplasm. Staining intensity of EGFR was directly correlated with nuclear grade (p=0.000) and TNM stage (p=0.015). PCNA index was significantly higher in EGFR-positive tumors than in EGFR- negative tumors. There was a statistically significant positive correlation between PCNA index and increasing staining intensity of EGFR (p=0.000). In univariate survival analysis, EGFR expression was significantly associated with shortened survival. However, EGFR expression was not an independent prognostic factor by multivariate analysis. These findings suggest that EGFR expression may be an important cause of tumor cell proliferation in renal cell carcinoma and further studies are needed to evaluate whether EGFR expression analysis provides independent prognostic information.
Carcinoma, Renal Cell*
;
Cell Membrane
;
Cell Proliferation*
;
Cytoplasm
;
Epidermal Growth Factor*
;
Glycoproteins
;
Humans
;
Multivariate Analysis
;
Proliferating Cell Nuclear Antigen
;
Receptor, Epidermal Growth Factor*
6.The Changes of Plantar Pressure and Pathway of Center of Pressure in Foot during the Gait in Normal Preschool Children with Age.
Ha Suk BAE ; Chang Il PARK ; Ji Cheol SHIN ; Ji Woong PARK
Journal of the Korean Academy of Rehabilitation Medicine 2001;25(6):1041-1047
OBJECTIVE: To find out the changes of the plantar pressure distribution of foot and the pathway of center of pressure (COP) in normal preschool children with age. METHOD: Thirty-eight normal children aged 1 to 6 were participated in this study. We divided into three groups according to the age. Foot contact area, pressure of the foot and pathway of COP were measured using F-scan in-shoe measuring system (Tekscan Inc.) during the gait. RESULTS: The ratio of midfoot contact width to forefoot contact width was decreased with age (p<0.05). And the relative pressure of the medial midfoot was decreased with age (p<0.05). In the analysis of COP, the ratio of anteroposterior length of COP to total contact length was significantly increased (p<0.05), and the ratio of mediolateral width of COP to forefoot contact width was tend to decrease. CONCLUSION: We can identify the characteristics and changes of the foot pressure distribution and the pathway of COP in preschool children with normal foot using F-scan system. These quantitative data of foot scan are useful for evaluating the foot pathology in preschool children during the gait.
Child
;
Child, Preschool*
;
Foot*
;
Gait*
;
Humans
;
Pathology
7.Prosthetic Gait Training in Individuals with Pathologic Conditions and Associated Pain on the Non-Amputated Side
Seongeun PARK ; Su Ji LEE ; Ji Cheol SHIN
Clinical Pain 2023;22(2):146-151
Leg amputation causes serious complications in walking and ultimately leads to functional impairment. Usually, the non-amputated side is considered as the dominant leg during prosthetic gait training. However, if the non-amputated side is affected by pathological conditions and has associated pain, it is necessary to determine whether it can be considered as the dominant leg. This case series presents four individuals who underwent leg amputations who also had pathologic conditions and pain in the non-amputated legs. A functional goal was established for each patient and individualized step-by step prosthetic gait training strategies were applied. Consequently, we found out that functional outcomes could be achieved even in cases with accompanying complications, such as fractures, nerve injuries, or pain, in the non-amputated leg.
8.Comparison of Speech-Language, Mental-Motor Development and Brain Radiologic Findings in Children with Cerebral Palsy and Other Delayed Development.
Eun Sook PARK ; Chang Il PARK ; Ji Chan CHANG ; Ji Cheol SHIN ; Ji Eun PARK
Journal of the Korean Academy of Rehabilitation Medicine 1999;23(5):918-925
OBJECTIVE: To evaluate the characteristics of speech-language development and to find out the relationship between them and radiological findings, and mental/motor developmental quotient in the children with cerebral palsy and other delayed development. METHOD: Fifty-eight children with cerebral palsy or delayed development were evaluated with Bayley scales of infant development, brain magnetic resonance imaging (MRI), and single photon emission computerized tomography (SPECT). At the same time, the speech-language development using several evaluation batteries was assessed. RESULTS: Most of the children with cerebral palsy or delayed development showed delay in speech-language development. There was no relationship between speech-language development and presence of the lesion on brain MRI or SPECT, and mental/motor developmental quotient. CONCLUSION: Speech-language development was delayed in most of the children with cerebral palsy or other delayed development. Therefore, early interventions for speech-language development and comprehensive speech therapy are required for improving functional outcome in these children.
Brain*
;
Cerebral Palsy*
;
Child Development
;
Child*
;
Early Intervention (Education)
;
Humans
;
Magnetic Resonance Imaging
;
Speech Therapy
;
Tomography, Emission-Computed, Single-Photon
;
Weights and Measures
9.Nasal Septum Perforation of Welders.
Choong Ryeol LEE ; Cheol In RYU ; Ji Ho LEE ; Jeong Hak KANG ; Seong Kyu KANG ; Jung Sun YANG ; Yong Cheol SHIN
Korean Journal of Occupational and Environmental Medicine 1998;10(3):404-411
Six cases of nasal septum perforation were found among welders during periodic physical checkup in 1997. Considering the size, shape and margin, the perforations were assumed to have been occurred several years before of which the diameter were 8~15 mm. To investigate the cause of perforation, we reviewed the past history of preemployment, the results of annual working environment survey and the material safety data sheets of welding rods and steels with which they have dealt, and analyzed the concentration of several metals of welding fume and the concentration of blood and urinary chromium. In the result, we presupposed that the nasal septum perforations of welders were due to chronic exposure to low level hexavalent chromium and/or nickel, and report these cases with literatures review.
Chromium
;
Material Safety Data Sheets
;
Metals
;
Nasal Septal Perforation*
;
Nasal Septum*
;
Nickel
;
Steel
;
Welding
10.Feasibility of Extracorporeal Shock Wave Therapy for Complex Upper Limb Morbidity in Breast Cancer Patient
Min Cheol HA ; Ji Cheol SHIN ; Yu Sang JUNG ; Sang Hee IM
Clinical Pain 2021;20(1):25-29
Upper limb morbidity including shoulder pain, lymphedema, adhesive capsulitis, myofascial pain syndrome, and limited range of motions (LROMs) occurs frequently in breast cancer patients. Especially restricted upper limb motion aggravated by chronic lymphedema results in functional limitation and impaired activities of daily living (ADL). However, conventional rehabilitation therapy including complex decongestive therapy and stretching exercise is insufficient for managing advanced breast cancer patients with complex upper limb morbidity. Here, we report a case of breast cancer-related chronic lymphedema in a 62-years old female with severe LROM in all joints of the affected upper extremity that caused severe disability in ADL. Significant improvements in range of motion and upper extremity function were observed after serial extracorporeal shock wave therapy (ESWT), combined with conventional rehabilitation therapy. Therefore, ESWT might be recommended for managing the extensive limited joint motion which causes functional decline in a patient of chronic lymphedema with trophic skin change.