Churg-Strauss syndrome (CSS) is a very rare disease which combines the features of asthma, hypereosinophilia, multisystem necrotizing vasculitis and extravascular granuolma. To our knolwedge, there have been four reports in Korean journals, but none in dermatology journals. We report a 37-year-old male who had allergic rhinitis, pansinusitis, a history of atopic dermatitis, multiple prurigo-nodularis like skin lesions, non-fixed interstitial lung in-filtration, hypereosinophilia and subclinical asthma. Clinical and histopathological features of his skin lesions were nonspecific where perivascular lymphocytic infiltration and mild lymphocytic vasculitis were shown. The presence of a pituitary mass and proximal myopathy as op-posed to peripheral neuropathy have not been reported in previous reports of CSS. However, other features of our patient met the criteria of CSS.
Adult ; Asthma ; Churg-Strauss Syndrome* ; Dermatitis, Atopic ; Dermatology ; Humans ; Lung ; Male ; Muscular Diseases ; Peripheral Nervous System Diseases ; Rare Diseases ; Rhinitis, Allergic ; Skin ; Vasculitis

Mucinous carcinoma can occur in non-cutaneous visceral sites and may metastasize to the skin. Thus it is important to exclude the possibility of a non-cutaneous visceral primary tumor before diagnosing primary mucinous carcinoma of the skin (PMCS). We describe a PMCS with unusual histopathological 6ndings. Although the microscopical, immunohistochemical, and ultrastructural characteristics of PMCS have been well defined, only less than sixty cases have been published since the disease was first reported by Lennox. This is an unusual case where combined features of apocrine carcinoma and predominant cribriform patterns reminiscent of adenoid cystic carcinoma exist in part, with highly anaplastic cellular features and frequent mitosis. To our knowledge, there have been no reports of this rare neoplasm in Korea.
Adenocarcinoma, Mucinous* ; Carcinoma, Adenoid Cystic ; Korea ; Mitosis ; Mucins* ; Skin*

Epidermal nevus syndrome is defined as the association of epidermal nevi with abnormalities of the other organ systems, and is regarded as one of the neurocutaneous syndromes. However, till now, epiderrnal nevus syndromi has not been reported with either Morning glory syndrome or intestinal pseudoobstruction. We experienced a case of a 7-year old rnale who had had multiple epidermal nevi on the scalp and forehead and solitary larg cafeau lait spot on his chest since birth. He had histories of failure to thrive and mental retardation, but no seizures. He also had histories of frequent diarrhea and abdominal distension. Physical examination showed abnormalities of the skin, teeth, and Morning glory syndrome of both oplic discs. Colon study, small bowel series and biopsy showed intestinal pseudoobstruction. Skeletal survey revealed a difference between the left upper extremity and the right one.
Biopsy ; Child ; Colon ; Diarrhea ; Failure to Thrive ; Forehead ; Humans ; Intellectual Disability ; Intestinal Pseudo-Obstruction* ; Neurocutaneous Syndromes ; Nevus* ; Parturition ; Physical Examination ; Scalp ; Seizures ; Skin ; Thorax ; Tooth ; Upper Extremity

The cutaneous manifestations of Acquired immunodeficiency syndrome(AIDS) include many conditions and can give some diagnostic clues to early detection of HIV infection. We report the case of a 32-year old man in whom AIDS initially manifested itself with herpes zoster and multiple episodes of purpuras(idiopathic thrombocytopenic purpura). He also had seborrheic dermatitis, oral candidiasis, and proximal subungual onychomycosis.
Acquired Immunodeficiency Syndrome* ; Adult ; Candidiasis, Oral ; Dermatitis, Seborrheic ; Herpes Zoster* ; HIV Infections ; Humans ; Onychomycosis ; Purpura, Thrombocytopenic, Idiopathic