No abstract available.
Pigmentation*

No abstract available.
Pigmentation*

No abstract available.
Lymphadenitis* ; Parotid Gland* ; Tuberculosis, Cutaneous* ; Tuberculosis, Lymph Node

No abstract available.
Carcinoma, Squamous Cell* ; Epithelial Cells* ; Porokeratosis*

No abstract available.
Alopecia Areata* ; Alopecia* ; Bone Density*

No abstract available.
Cutaneous Fistula ; Fistula*

Bier's spots present as vascular mottling, and this consists of small, irregular macules surrounded by a red to cyanotic background. The macules most commonly occur on the arms and legs of young adults, but they may also appear on the trunk. They are considered a vascular anomaly, with vasoconstriction in the pale areas and vasodilatation in the erythematous skin. Although Bier's spots are occasionally discovered in young adults, they are still a challenge to differentiate from other hypopigmentation disorders. We report here on two cases of Bier's spots on the extremities and trunk of 2 young adults.
Adult ; Arm ; Extremities ; Humans ; Hypopigmentation ; Leg ; Male ; Skin ; Vasoconstriction ; Vasodilation ; Young Adult

Systemic corticosteroid arrests the progression of vitiligo and leads to repigmentation, but it may produce side effects. It has been reported that the maximum effect for corticosteroid can be achieved without major side effects when it is used at high doses over a short period of time. Recently, narrowband UVB has been used to treat vitiligo. However, there have been no reports on the effectiveness for a combined treatment with narrowband UVB and systemic corticosteroid. We encountered 2 cases of vitiligo patients who had rapid and effective repigmentation after combination therapy with high dose methylprednisolone and narrowband UVB. Intravenous high dose (25 mg/kg) of methylprednisolone for 3 days was followed by narrowband UVB once or twice weekly. After 2 months, rapid improvements were seen in both patients with >75% repigmentation. Combination treatment with high dose methylprednisolone therapy and narrowband UVB may be an effective therapeutic option for vitiligo.
Humans ; Methylprednisolone ; Vitiligo

Scedosporium apiospermum is a rising opportunistic fungus that may infect immunocompetent individuals and may cause often fatal disease among the increasing immunosuppressed patient population. This pathogen is typically difficult to treat because of its particular resistance to commonly used antimycotic drugs. We describe an 83-year-old male patient with a history of long-term corticosteroid treatment for chronic prurigo simplex, who developed multiple suppurative nodules on a erythematous plaque at the right forearm. Histological examinations revealed granulomatous infiltration with hyphae and spores in dermis and fungal cultured isolation for definitive diagnosis showed S. apiospermum. Treatment was started with oral fluconazole, but skin lesions were getting worse. Then patient was treated with 200 mg of intravenouse itraconazole daily. Skin lesions showed a marked improvement after 1 week, and completely healing after 3 weeks.
Aged, 80 and over ; Dermis ; Fluconazole ; Forearm ; Fungi ; Humans ; Hyphae ; Itraconazole ; Male ; Methylmethacrylates ; Polystyrenes ; Prurigo ; Scedosporium ; Skin ; Spores

IgG4-related disease (IgG4-RD) is a new disease entity characterized by elevated serum IgG4 and infiltration of IgG4+ plasma cells in tissue. IgG4-RD can involve various organs, and skin could also be affected. The manifestations of IgG4-related skin disease (IgG4-RSD) are not characteristic, however it usually presents with multiple erythematous nodules or plaques with itching sensation. We report two cases of IgG4-RSD. Histological studies of these cases revealed infiltration of numerous plasma cells and mononuclear cells in the entire dermis. Some plasma cells were strongly positive for IgG4 stain. IgG4-RSD is a treatable disease with systemic corticosteroids. Thus, clinicians should obtain a biopsy and identify IgG4-positive cells for an accurate diagnosis.
Adrenal Cortex Hormones ; Biopsy ; Dermis ; Diagnosis ; Immunoglobulin G ; Plasma Cells ; Pruritus ; Sensation ; Skin Diseases* ; Skin*