This study was performed in the Korean recruits to determine the prevalence and the sites of predilection of the nevi involving melanocytes. The results were summarized as follows; 1) 411 of 2311(17. 7%) recruits examined were found to have nevus spilus, most prevalent in the trunk. The lesions were usually solitary but occasionally two or three lesions were found in a single individual. The prevalence of speckled lentiginous nevus was 0.49%,(2l/4247). The site of prevalence of progressive cribriform and zosteriform hyperpigmentation was 0. 80% (34/4247). The lesions were most commonly observed in the lower trunk and upper thighs. 4) The prevalence of Becker's nevus was 0.45%(19/4247). The lesions were most commonly observed in the shoulder and its surrounding areas. 5) Persistent Mongolian spot were observed in 2. 73% (63/2311). The proportion of extrasacral spots to sacral spots was increased to almost half of the entire spots. 6) Blue nevi were observed in 0. 48M (11/2311), most frequently in the sacral area.
Adolescent* ; Humans ; Hyperpigmentation ; Melanocytes* ; Mongolian Spot ; Nevus* ; Nevus, Blue ; Prevalence ; Shoulder ; Thigh

We report a case of acral persistent papular mucinosis in a 5 year-old female with multiple papules on both dorsa of the hands, wrists and forearms. Examination of a biopsy specimen showed a domeshaped lesion in the dermis composed of spindle-shaped fibrobla,sts and widely spaced collagen fibers. These spaces were filled with mucinous material, as demonstrated by positive staining with aleian blue at pH 2.5 and pH 0.5.
Biopsy ; Child, Preschool ; Collagen ; Dermis ; Female ; Forearm ; Hand ; Humans ; Hydrogen-Ion Concentration ; Mucinoses* ; Mucins ; Scleromyxedema ; Wrist

Reactive perforating collagenosis, first described by Mehregan et al in ]967, is a skin disorder characterized by transepidermal eliniination of altered collagen fibers. This rare disease appears as recurrent, umbilicated, crusted papules in response to minor trauma. We report here a case of reactive perforating collagenosis in a 21-year-old man. Examination of the skin revealed a number of centrally umbilicated, asymptomatic papules filled with keratotic plugs in various development and regression. The lesions were distributed on the dorsa of the hands, face, and neck. The biopsy spccimen showed a few of thin bundles of collagen which v ere extruded from the dermis through the atrophic epidermis and the turinels within the epidermis, reaching the buttom of the plug.
Biopsy ; Collagen ; Dermis ; Epidermis ; Hand ; Humans ; Neck ; Rare Diseases ; Skin ; Young Adult

Granuloma gluteale infantum may be considered a complication oi the primary irritant type of diaper dermatitis and a modern disease due to the change in tae are of the napkin area. Most patients were infants who had worn plastic diapers and were treated with fluorinated topical corticasteroid cream for their diaper dermatitis. The lesions comorise one or several, soft and reddish brown or livid purple nodules on the napkin area. We report a typical case of granuloma gluteale infantum in a 13-month old female who had been treated with topical cortieosteroid crearn for her diaper derniat;lis. The granuloma regressed spontaneously after withdrawl of the topical corticosteroid and restricted use of the occlusive plastic diaper.
Dermatitis ; Female ; Granuloma* ; Humans ; Infant ; Plastics

No abstract available.
Poroma*

The close similarity of acrokeratosis verruciformis(AKV) to the acral lesions of Dariers disease is well known. However, the exact relationship between the two disorders has not been satisfactorily resolved. A case of Dariers disease associated with guttate leukoderma and AKV is presented. The patient was a 17-year-old male who had dark cursted papules on the neck and lower abdomen, flat-topped keratotic papules on the dorsal surface of hoth hands, and white macules disseminated on the trunk and lower extremities of 7 years duration. The histopathologic examination of the lesion on the lower abdomen revealed parakeratotic plugs, corps ronds, and suprabasal clefts. The lesion on the dorsum of the hand showed compact hyperkeratosis, acanthosis, and papillomatosis with the pattern of church spires. The leukodermic lesion revealed decreased melanin content in the epidermal cells.
Male ; Humans

No abstract available.

Among the patients visting Department of Dermatology, Chungman National University, 58 cases had various side effects due to the malpractice of skin disorders. We analysed these 58 cases and the results can be summerized as follows ; 1. 37 cases(64%) were in the second and third decades and 11 cases(19%) were under 19 years-old. 2. Drug medication from pharmacy was the most common(79%), and then local clinics(12%), herb clinics(9%) in decreasing orders. 3. In the route of administration, oral ingestion(38%) was the most common, and 47 cases (81%) were medicated with adrenocorticoids. 4. In motivation to the visit, 31 cases(53%)were by advice, 15 cases by advertizement and 12 cases (21%) by themselves. 5. Acne and psoriasis were about a half of pre-existing skin diseases. 6. Side effects due to malpractice may be divided into 5 items : systemic side effects due to adrenocorticoids (59%), aggravation of pre-existing skin diseases (22%), topical side effects due to adrenocorticoids (10%), chemical irritation and burn (7%), and mercury intoxication (2%) in decreasing orders.
Acne Vulgaris ; Administration, Oral ; Burns ; Dermatology ; Humans ; Malpractice* ; Motivation ; Pharmacy ; Psoriasis ; Skin Diseases* ; Skin* ; Young Adult

Exogenoue exposurea to pathogenic fungi have been suggested as causes of acute atta.eks of tinea pedis. Psthogenic fungi is rarely present on the skin aurfaces without cauaing definite and characteristic reactions. However, it was suspected by eome observers that pathogenic fungi might be more or liesa normal inhabitant of the human skin. Alterations in host susceptibility and loss, of local immunity are more to blame than new exposure to exogenous micro-ganisms. To determine this point, fungal culture was done from the fourth toe web of 824 high school students. The results of the study were summarized as follows,' l. Among 824 cases, 780 cases(94.7%) had grossly normal appearing toe web and 44 cases(5,3%) were suspected superficial fungal infection. 2. Positive rate of KOH examination was 4.6%(36,'780) in normal toe web and 45.4%(20/44) in dermatophytic lesion. 3, The positive rate of fungal culture from normal and infected toe web are 7.9 %(62/780) a.nd 40.9%(18/44), respectively. In the normal toe web, Trichophyton rubrum(66.1%), T, entagrophytea(include T. interdigitaLe) and Epidermophyton, floccosum(3.2%) were isolated. In the dermatophytic lesion, T. rubrurn(88.8%) and T. me ntagrophytes(11.2% ) w ere isolated. Although toe webs do not present clinical symptoms and signs, pathogenic fungi as a normal inhabitant can be isolated from clinically normal toe webs. Some of these cases, therefore, will develope to tinea pedis in time.
Epidermophyton ; Fungi ; Humans ; Skin ; Tinea Pedis ; Toes* ; Trichophyton

The formation of spontaneous rosettes between human lymphocytes and sheep erythro ytes under suitable conditions is a constant feature of T-lymphocytes. Recently. It has been demonstrated in the mouse, rat, guinea pig and in man that a certain proportion of peripheral blood lymphocytes has the property to bind autolognus erythrocytes in vitro. These lymphocytes are called auiologous rosette forming cells(ARFC). Although there are several reports on human ARFC. the results are not in accordance. The present study was undertaken to demonstrate the autologous rosette forming property of human peripheral blood lymphocytes, and to enumerate the percentage of ARFC in different sex and age guoups. Fifty healthy persons entered this study between Martch and September. 1980. at the Department of Dermatolgy, Seoul National Universty Hospital. The method of quantitation of AREC was s sight modification of that of Lambermont et al(1977). The results were as follows.
Male ; Humans ; Mice ; Animals