1.Important differential in a patient presenting with neuropsychiatric symptoms: Anti-N-Methyl-D-Aspartate receptor encephalitis
The Medical Journal of Malaysia 2017;72(5):306-307
Anti-N-Methyl-D-Aspartate receptor (NMDAR) encephalitis is
an immune mediated condition, which remains relatively
unknown in Malaysia outside tertiary hospitals with
neurology unit. It is often misdiagnosed as a psychiatric
illness before definitive treatment is instituted. We report
here an 18-year-old man who initially presented to the
psychiatry unit before he was subsequently diagnosed as
having anti-NMDAR encephalitis. To our knowledge, this is
the first reported case of anti-NMDAR encephalitis in the
east coast of Peninsular Malaysia.
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
;
Encephalitis
2.Isoniazid-induced encephalopathy in an end-stage renal disease patient – A case report and literature review
The Medical Journal of Malaysia 2019;74(6):553-554
Patients with end stage renal disease have higher risk of
tuberculosis due to lower cell-mediated immunity. Standard
regime of anti-tuberculosis contains isoniazid where
neurological side effects such as seizure and
encephalopathy have been documented. We present a case
of isoniazid-induced encephalopathy in a haemodialysis
patient. A literature review on isoniazid-induced
encephalopathy was done. Recognition of this condition is
important as it is reversible with cessation of isoniazid and
institution of high dose pyridoxine
3.POEMS syndrome: A rare paraneoplastic presentation of spinal plasmacytoma
Jer Ming Low ; Sulaila binti Basiam ; Ahlam Naila binti Kori
The Medical Journal of Malaysia 2019;74(4):335-337
The acronym POEMS syndrome was coined for a unique
multisystem disorder characterised by peripheral
neuropathy, organomegaly, endocrinopathies, monoclonal
gammopathy and skin changes. We report a male patient
presenting to us with spinal plasmacytoma complicated with
paraplegia. He was subsequently diagnosed to have POEMS
syndrome and successfully treated with thalidomide and
dexamethasone. Post treatment, he is able to ambulate
independently