1.Heavy Chain V Regions of IgG Produced by Rheumatoid Synovial B Cells.
Jeong Won SOHN ; Dong Joon CHUNG ; Dong Hoon WOO ; Woo Ik HWANG
Korean Journal of Immunology 1997;19(2):171-180
No abstract available.
B-Lymphocytes*
;
Immunoglobulin G*
2.A Clinical Study of Recurrent Intussusception.
Hae Ok KIM ; Jae Oh KIM ; Jeong Woo SUK ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1981;24(12):1173-1184
No abstract available.
Intussusception*
3.Arteriovenous Fistula follwing Lumbar Discectomy
Sung Keun SOHN ; Jae Do KIM ; Woo Min JEONG ; Dong Seung LEE
The Journal of the Korean Orthopaedic Association 1989;24(1):299-303
Arteriovenous fistula could occur rarely followed by lumbar disk operation. There are very few case reports in the literature. We have experienced a case of arteriovenous fistula, which has been corrected surgically.
Arteriovenous Fistula
;
Diskectomy
4.Effects of Colloidal Gold 198Au on Synovial Membrane of Rabbits
Sung Keun SOHN ; Jae Do KIM ; Woo Min JEONG ; Jae Ik LEE
The Journal of the Korean Orthopaedic Association 1989;24(2):607-612
Colloidal gold 198Au were injected into 40 knee joints of rabbits for the study of the change of synovial membrane. We verified even distribution of Colloidal gold 198Au about knee joints by use of scintigraphy. After then, histopathological examinations were performed by periodic intervals. The following results are obtained form this study. l. Intra-articular injection of Colloidal gold 198Au into rabbit's knee joints resulted in a mild resctive inflammation at synovium. In was charscterized by an infiltration of eosinophils and by sclerotic changes in the subsynovium and by fibrosis of synovial vessels. 2. From this study, intra-articular injection of Colloidal gold 198Au may by benefit to treat the chronic synovial effusion in human.
Colloids
;
Eosinophils
;
Fibrosis
;
Gold Colloid
;
Humans
;
Inflammation
;
Injections, Intra-Articular
;
Knee Joint
;
Rabbits
;
Radionuclide Imaging
;
Synovial Membrane
5.Motion Study in the Fused Lumbar Spine
Sung Keun SOHN ; Jae Do KIM ; Woo Min JEONG ; Jae Ho JANG
The Journal of the Korean Orthopaedic Association 1989;24(2):523-531
In fusion of lumbar spine, every fused motion segments shows varisble limitation of motion in flexion, extension and lateral bending according to their types and level of fusion. The motion segment of lumbar spine is three joint complex which consists of posterior two articular facet joints and an anterior intervertebral disc. Nowadays, orthopedic surgeon prefer anterior fusion due to direct identification and removal of diseased tissue, reduction of fractured fragments, restoration of intrevertebral space, early rehabilitation and no damage of nerve root and cord, and is prefered short Segmental Spinal Instrumentation(e.g. Cotrel Dubousset Instrumentation, etc.) due to short and rigid fusion, no necessity of external support and low limitation of motion. We studied 58 cases of fused lumbar spine which had been operated since Sep.1983, by X-ray overlay method and 20 cases of healthy lumbar spine as eontrol group. In this study, we obtained following results ; 1. Harrington Rod Instrumentation reveals the most remarkable limitation of motion, whereas, C.D.I. and A.I.F. reveal the least limitation of motion. 2. Distinct differencies of motion are repersented by its range of fusion and range of motion in 2 segmental fusion reveals remarkable decreasement from range of motion in single segmental fusion. 3. In single segmental fusion, the most limitation of motion was represented in Harrington Rod Instrumentation and posterior fusion with bone graft. There is remarkable decreasement of flexion at lumbosacral junction by its site of fusion. 4.In double segmental fusion, the most limitation of motion was represented in Harrington Rod Instrumentation and there is no significant difference of motion by its site of fusion.
Intervertebral Disc
;
Joints
;
Methods
;
Orthopedics
;
Range of Motion, Articular
;
Rehabilitation
;
Spine
;
Transplants
;
Zygapophyseal Joint
6.A study of Cytokine in Peritoneal Fluid of Infertile Patients with Endometriosis.
Jeong Bae KANG ; Je Yong PARK ; Bum KIM ; Sung Joo KIM ; Woo Seok SOHN ; Hyun Tae KIM ; Pong Rheem JANG
Korean Journal of Fertility and Sterility 2000;27(1):91-98
OBJECTIVE: The presence of the various cytokines in human peritoneal fluid has been evaluated incompletely. Changes in cytokine lefels may be related to activation of peritoneal macrophage and T-lymphocyte, development of endometriosis, and infertility. This study assesses peritoneal fluid levels of interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10) and tumor necrosis factor-alpha (TNF-alpha) in infertile women with endometriosis and normal women without endometriosis. Design : Prospective and case-control study in university hospital. MATERIALS AND METHODS: Cytokine levels in peritoneal fluid obtained during laparotomy or laparoscopy from 21 patients in infertile patients in infertile patients with endometriosis and 24 controls undergoing laparotomy or laparoscopy with no evidence of pelvic endometriosis were determined by enzymelinked immunosorbent assay. RESULTS: The mean levels of interleukin-6 in infertile patients with endometriosis and controls were 72.7+/-23.7 pg/ml and 18.5+/-9.7 pg/ml respectively (p=0.02). Similarly, the mean levels of interleukin-8 in infertile patients with endometriosis was significantly higher than that of controls (445.0+/-89.6, vs 45.1+/-48.4, p=0.04). The mean concentration of interleukin-10 in infertile patients with endometriosis was significantly lower than that of controls (1.09+/-0.04 vs 2.19+/-0.03, p=0.03). The level of tumor necrosis factor-alpha was not significantly different between the two study groups. CONCLUSIONS: Increased IL-6 and IL-8 and decreased IL-10 levels in the peritoneal fluid may be related to pathogenesis in the endometriosis and infertility, suggesting that partially contribute to the disturbed immune regulation observed in infertili women with endometriosis.
Ascitic Fluid*
;
Case-Control Studies
;
Cytokines
;
Endometriosis*
;
Female
;
Humans
;
Infertility
;
Interleukin-10
;
Interleukin-6
;
Interleukin-8
;
Laparoscopy
;
Laparotomy
;
Macrophages, Peritoneal
;
Prospective Studies
;
T-Lymphocytes
;
Tumor Necrosis Factor-alpha
7.A Case Report of Cobb's Syndrome.
Eun Woo LEE ; Jeong Su LEEM ; Min Kyun SOHN ; Bong Ok KIM
Journal of the Korean Academy of Rehabilitation Medicine 1998;22(4):989-993
Cobb's syndrome, or cutaneomeningospinal angiomatosis, is a combination of the vascular skin nevus and angioma in the spinal cord within a corresponding segment or two to the dermatoms involved. A 15 year old girl showed the portwine nevus at T2-T11 dermatomes and multilevel spinal angioma at C7-L3 levels. She had suffered from a slowly progressive weakness of both lower extremities. Motor weakness of lower extremities improved after the combined rehabilitation management and radiation therapy for 4 months. We report the typical manifestations of Cobb's syndrome in a 15 year old girl with the brief review of literatures.
Adolescent
;
Angiomatosis
;
Female
;
Hemangioma
;
Humans
;
Lower Extremity
;
Nevus
;
Rehabilitation
;
Skin
;
Spinal Cord
8.The Study on Patient-Centeredness and Influencing Variables in Medical Students.
Seok Woo MOON ; Jeong Seok SEO ; Beom Woo NAM ; In Ki SOHN ; Woong HAHM ; In Hee CHO ; Hyuk Jung KWEON
Journal of Korean Neuropsychiatric Association 2006;45(4):363-371
INTRODUCTION: The practicing of patient-centered medical services means a change in the pattern of the nature of doctor-patient relationship. The doctor oriented relationship is now moving to the pattern that patients resolve problems autonomously and participate in the decision-making in medical services. Authors performed this study to investigate the patient centeredness and influencing variables in medical students. METHODS: Authors recruited 94 medical students before psychiatric clinical clerkship and all subjects were assessed by structured questionales including socio-demographic data, frequency of receiving doctor-patient relationship lectures, Minnesota multiphasic personality inventory (MMPI), Meyers-Briggs type indicator (MBTI), the authoritarian personality scale (AP), job satisfaction scale (JS), patient practitioner orientation scale (PPOS), problem-solving decision-making scale (PSDM), and Beisecker locus of authority in decision-making scale (BLAS), and the questionnaire of JS, PPOS, PSDM, and BLAS were rechecked after psychiatric clinical clerkship. RESULTS: After psychiatric clinical clerkship, the score of JS, PPOS were higher than before. The group who had a good memory for taking a doctor-patient relationship lecture showed higher scores of the BLAS and PSDM than unexposed group. The AP was related with MBTI, correlated with the subscale of MMPI, however, inversely correlated with PPOS after psychiatric clinical clerkship. CONCLUSION: The authoritarian personality trait was related not only with other personality trait including introversion and psychopathic deviation (Pd) but also with patient-centeredness. Taking a lecture in doctor-patient relationship is positively related to the patient-centeredness.
Clinical Clerkship
;
Humans
;
Introversion (Psychology)
;
Job Satisfaction
;
Lectures
;
Memory
;
MMPI
;
Surveys and Questionnaires
;
Students, Medical*
9.Detection of Mycobacterium tuberculosis from Peripheral Blood of Patients with Tuberculosis by Polymerase Chain Reaction.
Jang Wook SOHN ; Hee Jin CHEONG ; Heung Jeong WOO ; Woo Joo KIM ; Min Ja KIM ; Seung Chul PARK
Korean Journal of Infectious Diseases 1998;30(4):371-378
BACKGROUND: Conventional diagnostic methods of pulmonary tuberculosis, such as acid-fast bacilli staining and culture of sputum, have the disadvantages of low sensitivity and long incubation period, respectively. The diagnosis of extrapulmonary tuberculosis needs invasive procedures. We investigated the value of PCR-based detection of Mycobacterium tuberculosis from peripheral blood mononuclear cells for diagnosis of pulmonary or extrapulmonary tuberculosis. METHODS: The peripheral blood mononuclear cells were collected from 23 patients with pulmonary tuber-culosis( n=10) and extrapulmonary tuberculosis(n=13), in-cluding miliary tuberculosis(n=5), and 10 healthy indi-viduals as negative controls. A pair of primers was used to produce a 314 bp amplification product from the insertion element IS6110, which is specific for M. tuberculosis. PCR products were detected by agarose gel electrophoresis and southern hybridization using a IS6110 specific oligoprobe. RESULTS: Eight out of ten with pulmonary tuberculo-sis and 9 out of 13 patients with extrapulmonary tuber-culosis showed positive results, yielding 73.9%(17/23) positivity on PCR assay. All five patients with miliary tuberculosis were positive. None of the healthy indivi-duals showed positive results. CONCLUSION: The PCR assay for M. tuberculosis from peripheral blood seems to be useful for diagnosis of tuberculosis, especially miliary tuberculosis. Further studies about the value of the PCR assay in monitoring treatment response are needed.
Diagnosis
;
Electrophoresis, Agar Gel
;
Humans
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymerase Chain Reaction*
;
Sputum
;
Tuberculosis*
;
Tuberculosis, Miliary
;
Tuberculosis, Pulmonary
10.False-positive I-131 Scan by Contaminated Muffler in a Patient with Thyroid Carcinoma.
Han Kyung SEO ; Min Woo KIM ; Hwan Jeong JEONG ; Myung Hee SOHN
Nuclear Medicine and Molecular Imaging 2006;40(1):51-52
A 39-year-old female patient who had undergone a total thyroidectomy for a papillary thyroid carcinoma underwent a whole body scan with I-131. The I-131 scan was performed 72 hours after administering 185 MBq (5 mCi) of an I-131 solution. The anterior image of the head, neck, and upper chest showed multiple areas of increased uptake in the mediastinal area considering of functional metastasis. However, radioactivity was not evident in the image taken after removing her clothes and muffler. The image obtained after placing the muffler on the pallet showed that the radioactivity was still present. It is well known that artifacts on an I-131 scan can be produced by styling hair sputum, drooling during sleep, chewing gum, and paper or a cloth handkerchief that is contaminated with the radioactive iodine from either perspiration or saliva. This activity might be mistaken for a functional metastasis. Therefore, it is essential that an image be obtained after removing the patient's clothes. In this study, artifacts due to a contaminated muffler on the I-131 scan were found. These mimicked a functional metastasis of the mediastinal area in a patient with a papillary thyroid carcinoma.
Adult
;
Artifacts
;
Chewing Gum
;
Female
;
Hair
;
Head
;
Humans
;
Iodine
;
Neck
;
Neoplasm Metastasis
;
Radioactivity
;
Saliva
;
Sialorrhea
;
Sputum
;
Thorax
;
Thyroid Gland*
;
Thyroid Neoplasms*
;
Thyroidectomy
;
Whole Body Imaging