No abstract available.
Arthritis, Rheumatoid* ; Hand Deformities* ; Hand*

PURPOSE: Misdiagnosed breast cancer on screening mammography was retrospectively reviewed in an attempt to analyze the cause for the undiscovery and to determine findings that might have been suggested on the mammographic examination. MATERIALS AND METHODS: Of the 173 breast cancers that were pathologically proven, 17 breast cancers misdiagnosed on mammogram was retrospectively analyzed for the causes of the misinterpretation and predominant secondary findings. RESULTS: Three of the 17 were negative on mammography except for dense breast. Two patients had localized asymmetricity without visible mass. Ten patients had benign-looking mass which was well-defined (n=5), partially defined(n=2), multiple (n=l), or included benign-looking calcifications(n=2). Remaining two cases were retrospectively diagnosed as misinterpreted breast cancers. Various secondary findings such as were useful in the diagnosis of breast cancer. CONCLUSION: Meticulous observation could improve the diagnostic yield of breast cancer in mammography.
Breast Neoplasms* ; Breast* ; Diagnosis ; Humans ; Mammography* ; Mass Screening ; Retrospective Studies*

OBJECTIVE: To evaluate whether the rate of early mouse embryonal development could be enhanced by cumulus cell coculture in vitro. METHODS: Ham's F-10 culture media supplemented with 0.4% bovine serum albumin were used. Two-cell F1 mouse embryos were cultured in media with or without cumulus cells of female ICR mouse embryo for 96 hours, and the rates of embryonal development were observed and compared. RESULTS: The percentage of hatched blastocyst in the coculture group was significantly higher than that in the control group by 87.3% vs 64.8% respectively (p< 0.05). CONCLUSION: This study provides confirmative information that cumulus cell coculture will be useful in enhancing early mouse embryonal development.
Animals ; Blastocyst ; Coculture Techniques* ; Culture Media ; Cumulus Cells* ; Embryonic Structures ; Female ; Humans ; Mice* ; Mice, Inbred ICR ; Serum Albumin, Bovine

PURPOSE: To analyse Doppler findings in patients with chronic venous insufficiency, and evaluate the usefulness of color Doppler ultrasonography. MATERIALS AND METHODS: Thirty-seven limbs in 29 patients were evaluated with color Doppler ultrasound for suspected chronic venous insufficiency. To determine luminal patency and valvular competence, the venous system was examined; more than 1 sec of reflux flow during Valsalva maneuver and after release of distal compression in the popliteal vein indicated incompetence. RESULTS: Venous insufficiency was seen in 30 cases (81%), and was Superficial in 14 (38%), deep in eight (21.5%), and combined in eight (21.5%). In seven limbs (19%), veins were normal. Six cases of insufficiency, four of which were deep, were combined with deep venous thrombosis. CONCLUSION: In cases of chronic venous insufficiency, color Doppler ultrasound is useful for defining the exact site of venous incompetence and evaluating venous luminal patency.
Extremities ; Humans ; Mental Competency ; Phenobarbital ; Popliteal Vein ; Ultrasonography* ; Ultrasonography, Doppler, Color ; Valsalva Maneuver ; Veins ; Venous Insufficiency* ; Venous Thrombosis

No abstract available.

BACKGROUND: As people have been interested in healt,h and as the microcomputers with multimedia steeing have been supplied more and more, there is increasing need of multimedia information about health. The CD-ROM, which is a representative multimedia tool, is capable of interacting between information-provider and users, offering audiovisual interface, and saving great deal of knowledge. METHODS: We developed the health-information system to provide ordinary people with hea1th information using multimedia tools. It, has 7 parts ; self-diagnosis, exploring human body, drug information, hospital information, first-aid treatment, Q and A, and medical common sense. We got image data such as figures, photos, X-rays, electrocardiograms and pathologic specimens with scanner and film scanner, also moving image(video) with video-capturing program. RESULTS & CONCLUSIONS: We hope the multimedia health-information system to become a useful methodology of patient education and to be used as an information source in medical information network in the near future.
CD-ROM ; Electrocardiography ; Hope ; Human Body ; Information Services ; Microcomputers ; Multimedia* ; Patient Education as Topic

No abstract available.
Myxoma*

For the chronic renal failure(CRF) patients arteriovenous fistula(AVF) is performed on the upper extremity. The primary site is usually the wrist including snuffbox where diameter of the vessels is small, usually one to three millimeters. The trainee of general surgery has been lack of experience of small vessel surgery. Here on the basis of experimental microsurgery, novel animal practice model of AVF was developed for the clinical application. Among several types of vascular anastomosis of AVF, side-to-side anastomosis with distal vein ligation were favored in this study. In brief, rats were anesthetized with intraperitoneal urethane injection and midline abdominal incision was made. Aorta and IVC below the left renal vein was exposed and seperated and mobilized carefully. Side-to-side and end-to-end anastomosis can be performed microsurgically. Loupe(x3.5-5) and experimental microscope may help to carry out vascular anastomosis confidently. The key-point of the procedure is that both corners of stomas were sutured for staying and from the one-end continuous sutures were done with total open-loop method.
Animals ; Aorta ; Arteriovenous Fistula* ; Humans ; Kidney Failure, Chronic* ; Ligation ; Microsurgery ; Rats* ; Renal Veins ; Sutures ; Upper Extremity ; Urethane ; Veins ; Wrist

BACKGROUND: Common and effective treatments for calcific tendinitis involve needling procedures. However, it has been widespread practice to refer patients with calcific tendinitis, which is a predominantly orthopedic condition, to radiology department. The purpose of this study was to compare clinical and radiological outcomes after ultrasound-guided needling for calcific tendinitis between the orthopedics and radiology department. METHODS: Seventy-seven shoulders (Group 1) and 38 shoulders (Group 2) treated in the radiology and orthopedic department, respectively. A fellowship-trained orthopedic surgeon and a musculoskeletal radiologist each performed the procedure of ultrasound-guided needle decompression with subacromial steroid injection. Clinical outcomes was evaluated using the visual analogue scale for pain (pVAS) and the American Shoulder and Elbow Surgeons (ASES) shoulder score before treatment and at each follow-up. The pre- and post-needling size and shape of the calcific deposits were compared between the two groups. RESULTS: We analyzed a total of 56 shoulders for Group 1 and 32 shoulders for Group 2. The mean age and sex ratio of the patients no significantly different. We found that the mean decrease in the diameter of calcification between pre- and post-needling was 9.0 mm for Group 1 and 13.1 mm for Group 2; the difference was significantly larger in Group 2 than in Group 1. Both groups showed improved pVAS and ASES scores after needling but the extent of these improvements did not differ with the type of operator. CONCLUSIONS: Needling decompression performed by orthopedic surgeons could a viable option for the treatment of calcific tendinitis.

Nine cases of primary localized cutaneous amyloidosis were studied by immunoperoxidase technique (ABC method) employing anti-keratin antibodies. All specimens were examined using consecutive paraffin sections to confirm the correspondence between amyloid existing area and reactive sites. Anti-keratin antibody 34pE which recognize 68, 58, 56.5, 56kd keratin peptides reacted with amyloid deposits in both lichen amyloidosus and macular amyloidosis. However, anti-keratin antibodies 34pB4 and 35pH did not react with amyloids. In general, Dylon staining positive material, keratin reacted with 34pE and amyloid P showed similar distribution in serial sections, but did not show the same one. Several keratin bodies reacted with 34pE, which were not stained with Dylon staining or antiamyloid P were found in the dermis of one specimen. These results suggest that immunohistochemical staining with antikeratin antibody 34pE using formalin-fixed, paraffin-embedded sections appeared to be a useful method in studying the histogenesis of primary localized cutaneous arnyloidosis.
Amyloid* ; Amyloidosis* ; Antibodies* ; Catalytic Domain ; Dermis ; Immunoenzyme Techniques ; Lichens ; Paraffin ; Peptides ; Plaque, Amyloid*