No abstract available.
Thioacetamide*

Background: Complicated acute pyelonephritis (APN) is a life-threatening condition that requires immediate intervention. This study examined the characteristics of APN occurring as a complication of ureteral stone. Methods: We retrospectively reviewed 85 patients diagnosed with APN complicated by ureteral stone between December 2006 and July 2017 at our institution. Patients with concomitant renal stone, multiple ureteral stones, ureteral strictures, ureteral cancer, and urogenital anomalies, including vesicoureteral reflux were excluded. Clinical characteristics including age, sex, underlying disease, medical history, stone characteristics, initial laboratory data, and the procedure used to correct urinary obstruction were summarized, and the risk factors associated with sepsis and septic shock were analyzed. Results: Sepsis was diagnosed at initial presentation in 62 patients, 17 of whom suffered from septic shock. Disease-related death did not occur in any patient. Previous history of stone (P = 0.015), leukocytosis (P < 0.001), elevated C-reactive protein levels (P = 0.006), and low albumin (P = 0.038) were significant risk factors for progression to sepsis. The absence of hypertension (P = 0.047), thrombocytopenia (P = 0.006), decreased erythrocyte sedimentation rate (ESR) (P = 0.003), elevated blood urea nitrogen (P = 0.016), and positive blood culture (P= 0.018) were significant predictors for progression to septic shock.Multivariate analysis revealed that previous history of stone (P = 0.015) was an independent risk factor for sepsis, while the absence of hypertension (P = 0.047), thrombocytopenia (P= 0.013), and decreased ESR (P = 0.009) were risk factors for shock. Conclusion The risk factors associated with the progression from APN to sepsis differed from those associated with the progression from sepsis to septic shock. Various factors should be considered while selecting treatment options based on the severity of APN associated with ureteral stone. It should be managed with aggressive treatment and close observation, especially in the presence of risk factors.

Pheniramine maleate(avil(R)) is a H1-antagonist that is derived from alkylamine. Skin reactions with parenteral administration of avil(R) are uncommon. A 29-year-old woman visited our department with a 3-year history of relapsing generalized multiple pruritic evanescent erythematous wheals after antihistamine and steroid injection. Intradermal skin test with Avil(R) was positive. We treated with 5 mg of mequitazine administration three times a day for 2 years.
Adult ; Female ; Humans ; Pheniramine* ; Skin ; Skin Tests ; Urticaria*

Tuberculosis generally affects the respiratory tract. In developing nations, the pericardium is the most common location of extrapulmonary tuberculosis; however, tuberculous pericarditis rarely appears as a localized mass or tuberculoma. We present here a case of a 62-year-old woman with pericardial tuberculoma. She had a history of effusive tuberculous pericarditis and drainage. Because she had taken regular medication over a period of six months, the pericardial mass with an adjacent lung nodule newly detected on the chest radiogram was initially suspected of being invasive lung cancer. Prior to pathologic confirmation, precise information from imaging tests, including computed tomography, magnetic resonance imaging, and positron emission tomography-computed tomography are helpful when making decisions regarding which methods should be used for surgical approach and treatment. Through imaging, our case showed typical features of pericardial tuberculoma and a favorable clinical course after two months with a change in antituberculous therapy.
Developing Countries ; Drainage ; Electrons ; Female ; Humans ; Lung ; Lung Neoplasms ; Magnetic Resonance Imaging ; Middle Aged ; Pericarditis, Tuberculous ; Pericardium ; Respiratory System ; Thorax ; Tuberculoma ; Tuberculosis

Multiple cutaneous reticulohistiocytoma, a unique pattern in the spectrum of the reticulohistiocytoses, is a rare reactive granulomatous condition. We report a case of multiple cutaneous reticulohistiocytoma in a 36-year-old female, who showed multiple, pruritic, yellow-reddish brown papules on her posterior neck and right upper back for 1 year. Histologically, numerous multinucleated giant cells with a ground glass appearance observed in the dermis. Immunohistochemical stains of CD68, Vimetin were positive. The lesions were subsided after applying topical steroid for 1 month.
Adult ; Coloring Agents ; Dermis ; Female ; Giant Cells ; Glass ; Histiocytosis, Non-Langerhans-Cell* ; Humans ; Neck

A few case of deep granulomatous cutaneous infection have been reported in the Korean dermatologic literature, but Trichophyton(T.) mentagrophytes granuloma is rare. We report a case of Trichophytic granuloma caused by T. mentagrophytes in a 10-year-old male, who showed three, mild pruritic, coin to walnut-sized, erythematous plaques with indurations and crusts on the face for 1 month. Fungal culture of the biopsy specimen and scales of the lesion revealed T. mentagrophytes. Histopathologic examination of the skin lesion showed chronic granulomatous inflammation in the dermis and fungal hyphae in the hair shaft. After four weeks of terbinafine administration, lesions were cleared with mild erythematous macules.
Biopsy ; Child ; Dermis ; Granuloma* ; Hair ; Humans ; Hyphae ; Inflammation ; Male ; Numismatics ; Skin ; Trichophyton* ; Weights and Measures

Trichophyton rubrum is an anthropophilic dermatophyte that is found all over the world, It has become one of the most important causative agents in tinea unguium and tinea pedis. But tinea capitis caused by T. rubrum is rare. Tinea capitis is uncommon in adult. We report a case of tinea capitis caused by T. rubrum in a 67-year-old female, who showed fine scaly erythematous pustules with alopecia on the frontal scalp for 2 months. Culture from a scalp lesion of patient on Sabouraud dextrose agar showed typical whitish cottony colonies of T. rubrum. The patient had been treated with terbinafine.
Adult ; Agar ; Aged* ; Alopecia ; Arthrodermataceae ; Female ; Glucose ; Humans ; Onychomycosis ; Scalp ; Tinea Capitis* ; Tinea Pedis ; Tinea* ; Trichophyton*

Psoriasis vulgaris, a disorder of partially genetic origin, affects 1-3% of the general population. Vitiligo, generally considered an autoimmune disease, affects 0.5% of the general population. Despite the relatively common occurrence of each disease, the concurrence of each disease in a patient has been considered unusual. It is difficult to discern any particular relationship between vitiligo and psoriasis. Assuming that vitiligo and psoriasis are pathogenetically distinct and are grouped independently of each other. We report a case of psoriasis vulgaris associated with vitiligo in a 19-year-old man. Diagnosis was confirmed by clinical and histopathological findings. He is being treated with narrow band UVB phototherapy.
Autoimmune Diseases ; Diagnosis ; Humans ; Phototherapy ; Psoriasis* ; Vitiligo* ; Young Adult

Trichilemmal carcinoma is a rare malignant neoplasm of hair follicle which is derived from or differentiates towards the outer root sheath. Despite the frequent presence of histologically malignant features, it has a relatively benign clinical behavior. We report a case of trichilemmal carcinoma in an 87-year-old woman who showed a solitary slightly tender, 1.5X2cm-sized, verrucous, erythematous nodule with crust on the vertex of scalp. In her past medical history, it had been excised at a private clinic without a histopathological evaluation and recurred 1 year later. Histopathologically, tumor cells showed PAS-positive cytoplasms and cytologic atypia with a few mitotic figures. The patient was treated with a wide surgical excision. She has had no evidence of recurrence or metastasis.
Aged, 80 and over ; Cytoplasm ; Female ; Hair Follicle ; Humans ; Neoplasm Metastasis ; Recurrence ; Scalp

Although dermatophytes are still the main etiologic agents of onychomycosis, some species of nondermatophytic molds and yeasts are also capable of invading the nails. Fusarium (F.) solani is a nondermatophytic mold which is saprophytic fungus in soil. Onychomycosis due to Fusarium species almost always involve the great toenails, particularly in the presence of traumatic or dystrophic abnormalities. We report a case of toenail onychomycosis caused by F. solani in a 42-year-old female. The patient presented with typical distal subungual onychomycosis. Direct microscopic examination of scrapings on the potassium hydroxide preparation revealed fungal elements and repeated cultures on Sabouraud's dextrose agar showed the same whitish to cream-colored, cottony colonies. Multiple, sickle-shaped, multiseptate macroconidia and long, slender monophialides were observed in the slide culture. We confirmed F. solani by gross and light microscopic morphology of the colony. The patient was treated with 250 mg of terbinafine daily for 3 months.
Adult ; Agar ; Arthrodermataceae ; Female ; Fungi ; Fusarium* ; Glucose ; Humans ; Nails ; Onychomycosis* ; Potassium ; Soil ; Yeasts