1.Electronic Commerce and e-Marketplace.
Journal of the Korean Medical Association 2000;43(11):1076-1085
No abstract available.
Commerce*
2.Late aortic dilatation and regurgitation after Ross operation.
Kim, Moon-Young ; Na, Chan-Young ; Kim, Yang-Min ; Seo, Jeong-Wook
The Malaysian Journal of Pathology 2010;32(2):129-35
The Ross operation, a procedure of replacement of the diseased aortic valve with an autologous pulmonary valve, has many advantages such as no need for anticoagulation therapy and similar valve function and growth potential as native valves. However secondary aortic disease has emerged as a significant complication and indication for reoperation. We report a 48-year-old woman who had Ross operation in 1997 for a damaged bicuspid aortic valve and severe aortic regurgitation due to subacute bacterial endocarditis complicated by aortic root abscess. In 2009, 12 years later, progressive severe aortic regurgitation with incomplete coaptation and mild dilatation of the aortic root was shown on echocardiography and contrasted CT, while the pulmonary homograft retained normal function. She subsequently underwent aortic valve replacement. Histopathological examination of the explanted neo-aortic valve and neo-arterial wall revealed pannus formation at the nodulus Arantii area of the three valve cusps, ventricularis, and arterialis. The amount of elastic fibres in the neo-aorta media was less than usual for an aorta of this patient's age but was similar to a pulmonary artery. The pathological findings were not different from other studies of specimens removed between 7 to 12 years after Ross operation. However, the pathophysiology and long-term implications of these findings remain debatable. Considering the anatomical and physiological changes induced by the procedure, separate mechanisms for aortic dilatation and regurgitation are worthy of consideration.
Aorta/*pathology
;
Aortic Valve/*surgery
;
Aortic Valve Insufficiency/*etiology
;
Cardiovascular Surgical Procedures/*adverse effects
;
Dilatation, Pathologic
;
Heart Valve Diseases/*surgery
;
Prostheses and Implants
;
Pulmonary Valve/*transplantation
3.Surgical Treatment of Isthmic Spondylolisthesis: Pedicle Screw Fixation, Posterolateral Fusion, and Posterior Lumbar Interbody Fusion with Cage after Wide Decompression.
Hwa Yeop NA ; You Young JEONG ; Woo suk KIM ; Hyoung Wook CHO
Journal of Korean Society of Spine Surgery 2003;10(2):119-126
STUDY DESIGN: A retrospective study. OBJECTIVES: To verify the advantages of adding gentle reduction and posterior lumbar interbody fusion (PLIF), using a cage to the usual posterolateral fusion (PLF), with pedicle screw instrumentation, in the surgical treatment of spinal stenosis with isthmic spondylolisthesis. SUMMARY OF LITERATURE REVIEW: The stabilization of isthmic spondylolisthesis, following decompression, is difficult. The PLIF, with a cage, offers anterior column support, reduction and a broad fusion base. MATERIALS AND METHODS: 31 patients were treated with wide decompression, pedicle screws fixation, PLF and PLIF, and followed up for more than 1 year. The degrees of slippage were grades I and II in 20 and 11 patients, respectively. The grade I patients were treated with gentle reduction of the slippage in the disc space, using a leverage maneuver with a Cobb's spinal elevator. The grade II patients were treated with the insertion of a pedicle screws, fixation of rods, reduction and distraction, and then insertion of a cage. After the procedure all the patients were evaluated for the reduction of spondylolisthesis, restoration of the disc space, radiological bony union and clinical results. RESULTS: Ninety percent of the patients were rated as excellent or good. Fusion of the PLIF occurred in all patients. The average reduction in the spondylolisthesis was 42.6 and 47.8% in the grade I and II patients, respectively. The average restorations of the disc spaces were 46.9 and 100.2% in the grade I and II patients, respectively. The maintenance of the reduction and disc height were excellent in the final follow-up radiographs. CONCLUSIONS: Adding gentle reduction and PLIF, using a cage, to the usual posterolateral fusion, with pedicle screw instrumentation, in the surgical treatment of spinal stenosis, with isthmic spondylolisthesis, showed satisfactory results in the reduction of the spondylolisthesis, the restoration of the disc height, the bony union and clinically.
Decompression*
;
Elevators and Escalators
;
Follow-Up Studies
;
Humans
;
Retrospective Studies
;
Spinal Stenosis
;
Spondylolisthesis*
5.A Case of Congenital Pericardial Defect Diagnosed by Computed Tomography.
Hong Youp CHOI ; Sang Wook LIM ; Joon Young KIM ; Byung Wook NA ; Kyung Wha WHANG ; Eun Mi JEONG ; Tae Yong KIM ; Dong Hoon CHA ; Jeung Sook KIM
Korean Circulation Journal 2000;30(10):1281-1284
Pericardial defect is a rare congenital cardiac disorder. Most patients were asymptomatic but some patients with partial pericardial defect occasionally complain acute symptoms such as angina, syncope, rarely sudden cardiac death. So, differential diagnosis with other ischemic or structural heart disease is crucial in the management of such patients. But there is no consistently successful diagnostic method. In the past, artificial diagnostic pneumothorax was used to document the absence of pericardium. However, it is not easily accepted due to excess morbidity and failure rate. Recently, echocardiography and more often, computed tomography, magnetic resonance imaging are used to confirm the diagnosis. We experienced a 52 years old male patient with atypical chest pain, who was diagnosed as complete left pericardial defect with computed tomography.
Chest Pain
;
Death, Sudden, Cardiac
;
Diagnosis
;
Diagnosis, Differential
;
Echocardiography
;
Heart Diseases
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Middle Aged
;
Pericardium
;
Pneumothorax
;
Syncope
6.Antiarrhythmic Effect of Artemisinin in an Ex-vivo Model of Brugada Syndrome Induced by NS5806
Hyung Ki JEONG ; Seo Na HONG ; Namsik YOON ; Ki Hong LEE ; Hyung Wook PARK ; Jeong Gwan CHO
Korean Circulation Journal 2023;53(4):239-250
Background and Objectives:
Brugada syndrome (BrS) is an inherited arrhythmia syndrome that presents as sudden cardiac death (SCD) without structural heart disease. One of the mechanisms of SCD has been suggested to be related to the uneven dispersion of transient outward potassium current (Ito ) channels between the epicardium and endocardium, thus inducing ventricular tachyarrhythmia. Artemisinin is widely used as an antimalarial drug. Its antiarrhythmic effect, which includes suppression of Ito channels, has been previously reported. We investigated the effect of artemisinin on the suppression of electrocardiographic manifestations in a canine experimental model of BrS.
Methods:
Transmural pseudo-electrocardiograms and epicardial/endocardial transmembrane action potentials (APs) were recorded from coronary-perfused canine right ventricular wedge preparations (n=8). To mimic the BrS phenotypes, acetylcholine (3 μM), calcium channel blocker verapamil (1 μM), and Ito agonist NS5806 (6–10 μM) were used.Artemisinin (100–150 μM) was then perfused to ameliorate the ventricular tachyarrhythmia in the BrS models.
Results:
The provocation agents induced prominent J waves in all the models on the pseudoelectrocardiograms. The epicardial AP dome was attenuated. Ventricular tachyarrhythmia was induced in six out of 8 preparations. Artemisinin suppressed ventricular tachyarrhythmia in all 6 of these preparations and recovered the AP dome of the right ventricular epicardium in all preparations (n=8). J wave areas and epicardial notch indexes were also significantly decreased after artemisinin perfusion.
Conclusions
Our findings suggest that artemisinin has an antiarrhythmic effect on wedge preparation models of BrS. It might work by inhibition of potassium channels including Ito channels, subsequently suppressing ventricular tachycardia/ventricular fibrillation.
7.Auricular Tophi Presenting as a Unilateral Auricular Mass Lesion.
Jeong Hyun LEE ; Jae Wook LEE ; Na Hye MYUNG ; Myung Whan SUH
Korean Journal of Audiology 2011;15(3):152-154
Tophus due to gout is most commonly found in the toes and ankles, but can also be found in the auricle. Although small nodules on the helix are sometimes found in gout patients, a large mass lesion on the back side of the auricle is rare. We report a patient who visited the otology clinic due to an auricular mass lesion, which was diagnosed as a large auricular tophus. A 17-year-old male patient who suffered from gout complained of a right side auricular mass. A 3 cm sized solid mass lesion was detected on the back side of the right canvum conchal cartilage. The mass was soft, non-tender, and well-circumscribed. The lesion was first found 1-2 years earlier. The size of the lesion had been slowly increasing, but had recently stopped growing. The mass was surgically removed for pathologic confirmation and cosmetic reasons. Specimens were composed of 2 irregularly shaped pieces of soft-gray tan and yellowish tissue. The upper larger tophus was attached to the cartilage and the lower smaller tophus was embedded inside the auricular cartilage. Pathologic findings suggested tophus with amorphous deposits and subepithelial tissue.
Adolescent
;
Animals
;
Ankle
;
Cartilage
;
Cosmetics
;
Ear Cartilage
;
Gout
;
Humans
;
Male
;
Otolaryngology
;
Toes
;
Triacetoneamine-N-Oxyl
8.A Case of Scrub Typhus Complicated with Acute Renal Failure Meningoencephalitis and Hepatitis.
Jong Sub KIM ; Bon Jeong KU ; Ki Ryang NA ; Seoun Mee OH ; Ki Tai BIN ; Seong Suk KIM ; Kang Wook LEE ; Young Tai SHIN
Korean Journal of Medicine 1997;53(3):436-439
Scrub typhus is a zoonosis transmitted by a chigger of trombiculid mite and manifested with fever, skin rash, myalgia, and hepatitis etc. The renal involvement of the disease is prese-ted with transient microscopic hematuria and/or proteinuria. However acute renal failure or meningoencephalitis is very rare. We report a case of scrub typhus manifested with acute renal failure, meningoencephalitis, and hepatitis. The patient was treated with doxycycline and continuous arteriovenous hemofiltration (CAVH) and recovered successfully.
Acute Kidney Injury*
;
Doxycycline
;
Exanthema
;
Fever
;
Hematuria
;
Hemofiltration
;
Hepatitis*
;
Humans
;
Meningoencephalitis*
;
Myalgia
;
Proteinuria
;
Scrub Typhus*
;
Trombiculidae
9.Relations between Worry, Attachment Styles and Perceived Parental Rearing in Primary School Children.
Sung Goo KANG ; Jin Hee SHIN ; Yu Na HWANG ; Eun Jeong LEE ; Sang Wook SONG
Journal of the Korean Academy of Family Medicine 2008;29(11):854-866
BACKGROUND: Worry, a core feature of anxiety disorder, is shown in not only children with anxiety disorder but also normal children. This study was conducted to determine the relationship between worry and family environment factors, especially, perceived parental rearing and attachment styles among children. METHODS: Five hundred and nine children participated in this study among 549 children in third, fourth, fifth and sixth grades in two primary schools located in Seoul and Seongnam from October 2007 to December 2007. Forty children did not agree with participation (rejection rate: 7.3%). Their degrees of worry, attachment styles and perceived parental rearing were investigated with questionnaires. RESULTS: The reliability of a questionnaire asking children's worry, PSWQ-C and a questionnaire asking perceived parental rearing, modified EMBU-C was appropriate with internal consistency (Cronbach's alpha of PSWQ-C: 0.92, Cronbach's alpha of modified EMBU-C: 0.68~0.89). Around 22.4% of children had insecure attachment (avoidant or ambivalent attachment) and scores of worry were high in both girls and boys. When children perceived their parental rearing behavior as anxious rearing, they were classified to have ambivalent attachment in many cases by themselves. And when they perceived the rearing as rejection many of them were classified to have avoidant or ambivalent attachment by themselves. Worry showed a significantly negative correlation in the cases where children answered their perceived parental rearing as emotional warmth and showed a significantly positive correlation with rejective and anxious rearing. CONCLUSION: This study found that children's worry was closely related with their perceived parental rearing and attachment styles. If the children's attachment, which has been developed while they have grown up, was insecure and they did not perceive parental rearing as emotional warmth, the intensity of worry, a core symptom of anxiety disorder, increased.
Anxiety Disorders
;
Child
;
Humans
;
Only Child
;
Parents
;
Rejection (Psychology)
;
Surveys and Questionnaires
10.Squamous Cell Carcinoma arising in Cystic Teratoma of the Ovary.
Dae Hyun JUNG ; Chong Ho KIM ; Tae Wook YOO ; Young Jeong NA ; Kyung Tai KIM ; Yeun Young HWANG ; Seung Sam PAIK ; Moon Hyang PARK ; Dae Woon KIM
Korean Journal of Obstetrics and Gynecology 1997;40(10):2355-2361
The cystic teratoma is the most common germ cell tumors in reproductive age women. The malignant change of cystic teratoma is rare, about 1~2%, and mostly change to squ-amous cell carcinoma. We experienced 4 cases of squamous cell carcinoma arising in cystic teratoma and re- port our cases with a brief review of the literature.
Carcinoma, Squamous Cell*
;
Female
;
Humans
;
Neoplasms, Germ Cell and Embryonal
;
Ovary*
;
Teratoma*