1.Cell proliferatiion status, p53 protein and epidermal growth factor receptor(EGFR) expression-correlation with early recurrence in colorectal adenocarcinoma.
Eun Sook LEE ; Jeong Won BAE ; Cheung Woung WHANG
Journal of the Korean Society of Coloproctology 1993;9(4):309-322
No abstract available.
Adenocarcinoma*
;
Epidermal Growth Factor*
;
Recurrence*
2.An analysis of 923 facial bone fractures in 685 patients at the Korean army forces.
Bae Jeong CHO ; Un Kyo PARK ; Jong Won LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(6):1049-1059
No abstract available.
Facial Bones*
;
Humans
3.A study of altered IL-6 and IL-10 expression in peritoneal fluid of endometriosis patients.
Kyung Suk LEE ; Jeong Bae KANG ; Hong Bae KIM ; Keun Young LEE ; Sung Won KANG
Korean Journal of Obstetrics and Gynecology 1999;42(11):2558-2563
OBJECTIVE: Endometriosis is a disease affecting a large population of women all over the world. A local sterile inflammation occurs in the peritonel cavity of patients with endometriosis. It suggests that immunological events play a major role in the pathogenesis of endometriosis. We have studied the levels of serveral T cell and monocyte derived cytokines, especially IL-6 (promoter of immune response) and IL-10 (inhibitor of immune response), in the peritoneal fluid of patients with endometriosis to characterize the change of immune response that occurs at the site of endometriosis. Method: This study was performed in Hallym university hospital from October, 1997 to October 1998 and enrolled 29 women with gross or microscopic findings of minimal to severe endometriosis in case group, and 28 women without visual evidence of pelvic endometriosis and with benign gynecologic disease in control group. IL-6 and IL-10 levels in the peritoneal fluid were determined using commercial ELISA and compared between endometriosis and controls and between fertile and infertile women with endometriosis and according to the revised American Fertility Society classification. RESULT: IL-6 was higher and IL-10 was lower in the peritoneal fluid of endometriosis group than of control group. Cyclic variations in the IL-6 concentrations were seen in endometriosis group : the concentrations in the secretory phase were significantly higher than those in the proliferative phase. In endometriosis group, IL-6 concentrations of infertile women were higher than fertile women. Both IL-6 and IL-10 in the peritoneal fluid of endomtriosis group did not show significant correlation according to r-AFS stages. CONCLUSION: Increased IL-6 and decreased IL-10 levels in the peritoneal fluid may be related to infertility and pathogenesis in the endometriosis, suggesting that partially contribute to the disturbed immune regulation observed in endometriosis.
Ascitic Fluid*
;
Classification
;
Cytokines
;
Endometriosis*
;
Enzyme-Linked Immunosorbent Assay
;
Female
;
Fertility
;
Genital Diseases, Female
;
Humans
;
Infertility
;
Inflammation
;
Interleukin-10*
;
Interleukin-6*
;
Monocytes
4.A Study of Altered Cell-Mediated Immunity in Peritoneal Fluid of Patients with Endometriosis.
Jeong Bae KANG ; Hyun Tae KIM ; Hong Bae KIM ; Keun Young LEE ; Sung Won KANG
Korean Journal of Obstetrics and Gynecology 1999;42(9):1965-1971
OBJECTIVE: Our purpose was to investigate the relationship between the levels of IL-6 and tumor necrosis factor-alpha in the peritoneal fluid(PF) of women with and without endometriosis and infertile women. Design: Prospective and case-control study. Setting: University hospital. Patients: Twenty-nine women with laparotomy or laparoscopic findings of minimal to severe endometriosis, and twenty-eight women with no visual evidence of pelvic endometriosis and with benign gynecologic disease. Main Outcome Measures: PF IL-6 and tumor necrosis factor-alpha levels were determined using commercial ELISA. IL-6 and tumor necrosis factor-alpha concentrations were compared among women with and without endometriosis, and with infertile and fertile women, and then also compared according the revised American Fertility Society classification. RESULTS: IL-6 and tumor necrosis factor-alpha concentrations were higher than in the PF of women with endometriosis than in matched normal controls. Cyclic variations in IL-6 concentrations were seen in PF from patients with endometriosis: the concentrations in the secretory phase were significantly higher than those in the proliferative phase. IL-6 concentrations were higher than in the PF among of infertile women than in fertile women. A significant correlation between PF IL-6 and tumor necrosis factor-alpha concentrations and endometriosis stage III and IV was noted. CONCLUSIONS: Increased PF levels of IL-6 and tumor necrosis factor-alpha in patients with endometriosis may be relate to endometriosis-associated infertility and to the pathogenesis of endometriosis suggesting that partially contribute to the disturbed immune regulation observed in patients with endometriosis.
Ascitic Fluid*
;
Case-Control Studies
;
Classification
;
Endometriosis*
;
Enzyme-Linked Immunosorbent Assay
;
Female
;
Fertility
;
Genital Diseases, Female
;
Humans
;
Immunity, Cellular*
;
Infertility
;
Interleukin-6
;
Laparotomy
;
Outcome Assessment (Health Care)
;
Prospective Studies
;
Tumor Necrosis Factor-alpha
5.Vaginal Hysterectomy Following Previous Pelvic Operation 212 Cases: Clinical Analysis and Operative Technical Study.
Jae Eung PARK ; Jong Ryoul KIM ; Jeong Bae KANG ; Hong Bae KIM ; Keun Young LEE ; Sung Won KANG
Korean Journal of Obstetrics and Gynecology 1999;42(8):1713-1719
OBJECTIVE: To determine whether hysterectomy by the vaginal route is safe and feasible in patients with previous pelvic operation. METHODS: A retrospective study of the records of Hallym University Hospistal patients who underwent vaginal hysterectomy performed by the senior author. Between January 1990 and January 1997, 212 patients who had previous pelvic operation were studied with special reference to operative difficulties, previous operation type, intraoperative complications, surgical time, hospital stay. RESULTS: 1. Patients characteristics was that ; The average age was 44.5+/-6.6 years old, the average parity was 2.3 , the average stay of hospitalization was 7.5+/-0.89 days, the frequency of Morcellation was in 24.5%, the average surgical time including associated procedure was 82+/-16.2 minutes, the average uterine weight was 164+/-85.1gm. 2. The most common previous pelvic operation was cesarean section(95 cases). 3. The most common indication was uterine myoma(51.9%). 4. Surgical technique used to gain access to the pouch of Douglas was done anteriorly; 52 patients of previous cesarean section(24.5%) and 112 patients of others operation(52.8%) were easily opened by blunt dissection, 43 patients of previous cesarean section(20.3%) and 5 patients of others operation(2.4%) were required sharp dissection. posterioly ; 190 patients(89.6%) were easily opened by blunt dissection, 22 patients(10.4%) were required sharp dissection. 5. Significant complications were bladder injury(1 case) , postoperative transfusion due to bleeding(6 cases). No cases of postoperative laparotomy was done and other minor compications were fever(15 cases), bladder retention(11 cases), others. CONCLUSIONS: It was possible to perform vaginal hysterectomy safely in patients with previous pelvic operation. Vaginal hysterectomy remains the method of choice for removal of the uterus of the previous pelvic operations in the absence of other contraindications.
Cesarean Section
;
Female
;
Hospitalization
;
Humans
;
Hysterectomy
;
Hysterectomy, Vaginal*
;
Intraoperative Complications
;
Laparotomy
;
Length of Stay
;
Operative Time
;
Parity
;
Pregnancy
;
Retrospective Studies
;
Urinary Bladder
;
Uterus
6.A Case of Epidermal Nevus Syndrome associated with Developmental Delay and Hypophosphatemic Rickets.
You Jeong KIM ; Young Yoo KIM ; Won Bae LEE
Journal of the Korean Pediatric Society 1999;42(12):1741-1745
Epidermal nevus syndrome is a rare disease which includes disorders of bone, central nervous system, eye, kidney, vasculature, body symmetry, skin, and rarely, hypophosphatemic rickets which have been observed in association with epidermal nevi. We experienced a case of epidermal nevus syndrome. He presented with epidermal nevi and bilateral abdominal wall hernias at birth and developed right hemiparesis, mental retardation, and multiple fractures due to hypophosphatemic rickets. He died of pneumonia at the age of 6.
Abdominal Wall
;
Central Nervous System
;
Hernia
;
Intellectual Disability
;
Kidney
;
Nevus*
;
Paresis
;
Parturition
;
Pneumonia
;
Rare Diseases
;
Rickets, Hypophosphatemic*
;
Skin
7.A Case of Epidermal Nevus Syndrome associated with Developmental Delay and Hypophosphatemic Rickets.
You Jeong KIM ; Young Yoo KIM ; Won Bae LEE
Journal of the Korean Pediatric Society 1999;42(12):1741-1745
Epidermal nevus syndrome is a rare disease which includes disorders of bone, central nervous system, eye, kidney, vasculature, body symmetry, skin, and rarely, hypophosphatemic rickets which have been observed in association with epidermal nevi. We experienced a case of epidermal nevus syndrome. He presented with epidermal nevi and bilateral abdominal wall hernias at birth and developed right hemiparesis, mental retardation, and multiple fractures due to hypophosphatemic rickets. He died of pneumonia at the age of 6.
Abdominal Wall
;
Central Nervous System
;
Hernia
;
Intellectual Disability
;
Kidney
;
Nevus*
;
Paresis
;
Parturition
;
Pneumonia
;
Rare Diseases
;
Rickets, Hypophosphatemic*
;
Skin
8.Primary Malignant Melanoma arising in Mucosa of the Palatine Tonsil: A case report.
Ki Jung YUN ; Hyang Jeong JO ; Hyung Bae MOON ; Sang Won YOON
Korean Journal of Pathology 1996;30(1):65-67
Maligant melanomas of the oral or nasal cavity, and the vulvovaginal area are relatively common among the melanomas of non-ocular mucosa. But, primary malignant melanoma arising in the mucosa of the palatine tonsil is rare. We present a case of primary malignant melanoma arising in the mucosa of the palatine tonsil. A 36-year-old male was admitted for evaluation of a recurrent sore throat. Tonsillectomy was performed on the basis of clinical suspicion of chronic tonsillitis. Grossly, the left tonsil was focally dark. Microscopically, the tonsillar mucosa was diffusely infiltrated with tumor cells. Tumor cells revealed numerous melanin pigments. Intraepithelial nests of tumor cells were noted, but pagetoid spread of tumor cells was not found. Tumor cells were positive for S-100 protein and HMB45 stain. There was no evidence of melanoma in the skin or eye.
Male
;
Humans
9.A study on the regional blood flow of the hand.
Ki Jeong WON ; Byeong Il PARK ; Yong Bae KIM ; Woon Jae YANG ; Jong Sup PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(5):969-974
No abstract available.
Hand*
;
Regional Blood Flow*
10.An experimental study & clinical appliance of EMLA(eutectic mixture of local anesthetics).
Ki Jeong WON ; Yong Bae KIM ; Byeong Il PARK ; Yeong Man LEE ; Jong Sup PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(5):911-916
No abstract available.