No abstract available.
Child* ; Constipation* ; Encopresis* ; Humans

No abstract available.
Infant ; Male ; Female ; Humans

A gastrofiberscopic evaluation was performed on 65 children complaining of upper gastrointestinal symptoms who visited the pediatric department of Hanil hospital from March 1991 to September 1992. Gastrofiberscopy was done without local anesthesia of pharynx and heavy sedation. To identify H. pylori infection, biopsy specimen was taken from the gastric antrum since Feb. 1992. The specimens were examined using the rapid urease test and Giemsa stain. The results were as follows: 1) Twenty nine patients were male, 36 patients were female. The frequency of age distribution was 6% in 3~5 years, 42% in 6~10 years and 52% in 11~15 years. The most of cases were between 11~15 years of age(52%). 2) The indications were recurrent abdominal pain(40%), epigastric pain(34%), hematemesis(14%), abnormal UGI series(10%) and severe vomiting(2%) 3) Among 26 patients with recurrent abdominal pain, gastrofiberscopy showed acute superficial gastritis in 6 patients and duodenitis in 4. The rest of the patients were normal(16 patients). With regard to epigastric pain, out of 21 patients 7 showed acute gastritis and 4 patients had duodenitis. The rest 10 patients were normal. Of 9 patients examined endoscopically for upper GI bleeding, no focus of bleeding were identified in 2 patients. The remaining 7 patients were bleeding from acute gastritis (3 patients), gastric ulcer (1), duodenal ulcer (2) and esophageal varix (1). The majority of the patients who had some abnormality on UGI series was endoscopically normal (7/8) and only one patient had duodenitis. The patient with severe vomiting was normal. 4) Among 21 patients H. pylori infection was found in 6 patients (29%). Gastrofiberscopic findings were normal in 4 patients, duodenal ulcer in 1 and acute gastritis in 1 patient. Gastric biopsy findings in H. pylori infected patients were chronic active gastritis in 4 patients and normal in 1 patient. 5) There were no serious complications during the endoscopic procedure. It was concluded that upper gastrointestinal endoscopy was useful means of identifying the upper gastrointestinal pathology in children with upper GI symptoms. As a result of better understanding and technological advances, a changing trend of wider and more rational application of the procedure is evident.
Abdominal Pain ; Age Distribution ; Anesthesia, Local ; Azure Stains ; Biopsy ; Child* ; Duodenal Ulcer ; Duodenitis ; Endoscopy, Gastrointestinal ; Esophageal and Gastric Varices ; Female ; Gastritis ; Helicobacter pylori ; Hemorrhage ; Humans ; Male ; Pathology ; Pharynx ; Pyloric Antrum ; Stomach Ulcer ; Urease ; Vomiting

No abstract available.
Creatinine* ; Humans ; Infant, Newborn*

No abstract available.
Diet* ; Humans ; Immunoglobulin E* ; Incidence* ; Infant*

Herpes simplex esophagitis can occur in those with normal immune function, but is more often seen in those who are immunocompromised. In one series, 5 percent of post-kidney transplant recipients had herpes esophagitis. We experienced a case of herpes simplex esophagitis, following renal transplantation in a 9 year old male. He complained of epigastric pain, nausea and blood-tinged vomiting. Endoscopic examination showed volcano ulcer, mucosal friability and multiple confluent ulcers covered by whitish exudates on elevated margin in the middle and lower esophagus. Microscopic findings revealed multinucleated giant cells, margination of chromatin, intense nonspecific inflammation and strong positive for herpes simplex virus immunohistochemical staining. Esophageal lesions and symptoms improved after acyclovir therapy.
Acyclovir ; Child* ; Chromatin ; Esophagitis ; Esophagus ; Exudates and Transudates ; Giant Cells ; Herpes Simplex* ; Humans ; Inflammation ; Kidney Transplantation ; Male ; Nausea ; Simplexvirus* ; Transplantation ; Ulcer ; Vomiting

No abstract available.
Child* ; Humans

PURPOSE: To investigate the relation of the gastric epithelial cell proliferation, apoptosis and genotypes of H. pylori in children. METHODS: Histologic grading by updated Sydney system, PCNA immunostaining, TUNEL method and the genotypes (cagA, picB and iceA) by PCR were performed in H. pylori positive (N=20) and negative (N=20) gastric biopsy specimens. RESULTS: PCNA index was significantly different between H. pylori positive children (77.4+/-13.12) and H. pylori negative children (52.3+/-12.20) (p=0.000). There were positive correlations between PCNA index and H. pylori density (r=0.624, p=0.000), polymorphonuclear neutrophil activity (r=0.460, p=0.005) and chronic inflammation (r=0.433, p=0.009). Apoptosis index of H. pylori positive children (0.70+/-0.411) was significantly higher than of H. pylori negative children (0.14+/-0.201) (p=0.000). Positive correlations between apoptosis index and H. pylori density (r=0.691, p=0.000), polymorphonuclear neutrophil activity (r=0.585, p=0.000) and chronic inflammation (r=0.535, p=0.001) were noted. As PCNA index increased, apoptosis index significantly increased (r=0.527, p=0.001). The positive rates of genotypes were cagA 90%, picB 75%, iceA1 60% and iceA2 15%, respectively. There were no significant correlations between the status of the genotypes and PCNA index, apoptosis index, the endoscopic findings and the histologic findings. CONCLUSION: PCNA index and apoptosis index in H. pylori positive children were higher than in H. pylori negative children but were not related to H. pylori genotypes. This study suggested that correlatively increased gastric epithelial cell proliferation and apoptosis are important to pathogenesis of H. pylori infection in children.
Apoptosis* ; Biopsy ; Child* ; Epithelial Cells* ; Genotype* ; Helicobacter pylori* ; Helicobacter* ; Humans ; In Situ Nick-End Labeling ; Inflammation ; Neutrophils ; Polymerase Chain Reaction ; Proliferating Cell Nuclear Antigen

Childhood obesity has rapidly increased in Korea during the past 20-30 years. Approximately 1 of 10 children and adolescents is obese. Appropriate prevention and intervention measures urgently need. Obesity prevention starts early in life, i.e., obesity prevention and education begins during the period of fetal development in utero. Behavioral changes are the most positively reflected during pregnancy. Infants should be fed breast milk, and inculcated with healthy eating and behavioral habits during infancy to ultimately establish a healthy lifestyle in children. For achieving a lifestyle and behavior that successfully allow children to overcome obesity, although individual motivation is important, active support of parents and family members is also imperative. Health care providers should also make an effort to actively prevent obesity and take necessary intervention actions. Although the efforts of individuals, family, and healthy care providers are important to prevent the rapid increase in obesity, primary prevention should be encouraged at a higher level. Schools should specifically aim at improving nutrition and physical activity by allocating times for healthy eating, playing, and physical education. Moreover, local communities should provide support by funding for safe recreational environments, such as playgrounds and walking tracks. Public health strategies in community and national policies, such as city planning, food marketing, and advertisements, are required for primary prevention of obesity.
Adolescent ; Child ; City Planning ; Eating ; Fetal Development ; Financial Management ; Health Personnel ; Humans ; Infant ; Korea ; Life Style ; Marketing ; Milk, Human ; Motivation ; Motor Activity ; Obesity ; Parents ; Physical Education and Training ; Pregnancy ; Primary Prevention ; Public Health ; Track and Field ; Walking

The childhood and adolescence is an important period for establishing lifelong health. If parents want their children to live a healthy life, they should fix their children a nutritionally balanced diet and they should encourage their children to have a healthy eating habits and active physical activity. The beginning of lifelong health should be breastfeeding which reinforces immunity. What parents need to do is preparing nutritionally balanced meals at certain place at regular times. Children themselves control the amount of food they need to take. The parents should be a role model of their children to improve their childrens' healthy lifestyle. After 2 years of age, fat intake must be gradually decreased to 30~35% of total energy intake. The parents should limit their children eating saturated or trans fatty acids. Sweet or salty taste should be given as late as possible, and the parents should make efforts to give their children fruits and vegetables at each meal. Also they have to serve milk, dairy products, beans, tofu which are abundant of calcium. Traditionally, physicians has been treating sick children but nowadays physicians have to ask about childrens' health before anything else and inform the parents what to do to keep their children healthy.
Adolescent ; Breast Feeding ; Calcium ; Child ; Dairy Products ; Diet ; Eating ; Energy Intake ; Fabaceae ; Fruit ; Humans ; Hypogonadism ; Life Style ; Meals ; Milk ; Mitochondrial Diseases ; Motor Activity ; Ophthalmoplegia ; Parents ; Soy Foods ; Trans Fatty Acids ; Vegetables