No abstract available.
Child* ; Constipation* ; Encopresis* ; Humans

No abstract available.
Infant ; Male ; Female ; Humans

A gastrofiberscopic evaluation was performed on 65 children complaining of upper gastrointestinal symptoms who visited the pediatric department of Hanil hospital from March 1991 to September 1992. Gastrofiberscopy was done without local anesthesia of pharynx and heavy sedation. To identify H. pylori infection, biopsy specimen was taken from the gastric antrum since Feb. 1992. The specimens were examined using the rapid urease test and Giemsa stain. The results were as follows: 1) Twenty nine patients were male, 36 patients were female. The frequency of age distribution was 6% in 3~5 years, 42% in 6~10 years and 52% in 11~15 years. The most of cases were between 11~15 years of age(52%). 2) The indications were recurrent abdominal pain(40%), epigastric pain(34%), hematemesis(14%), abnormal UGI series(10%) and severe vomiting(2%) 3) Among 26 patients with recurrent abdominal pain, gastrofiberscopy showed acute superficial gastritis in 6 patients and duodenitis in 4. The rest of the patients were normal(16 patients). With regard to epigastric pain, out of 21 patients 7 showed acute gastritis and 4 patients had duodenitis. The rest 10 patients were normal. Of 9 patients examined endoscopically for upper GI bleeding, no focus of bleeding were identified in 2 patients. The remaining 7 patients were bleeding from acute gastritis (3 patients), gastric ulcer (1), duodenal ulcer (2) and esophageal varix (1). The majority of the patients who had some abnormality on UGI series was endoscopically normal (7/8) and only one patient had duodenitis. The patient with severe vomiting was normal. 4) Among 21 patients H. pylori infection was found in 6 patients (29%). Gastrofiberscopic findings were normal in 4 patients, duodenal ulcer in 1 and acute gastritis in 1 patient. Gastric biopsy findings in H. pylori infected patients were chronic active gastritis in 4 patients and normal in 1 patient. 5) There were no serious complications during the endoscopic procedure. It was concluded that upper gastrointestinal endoscopy was useful means of identifying the upper gastrointestinal pathology in children with upper GI symptoms. As a result of better understanding and technological advances, a changing trend of wider and more rational application of the procedure is evident.
Abdominal Pain ; Age Distribution ; Anesthesia, Local ; Azure Stains ; Biopsy ; Child* ; Duodenal Ulcer ; Duodenitis ; Endoscopy, Gastrointestinal ; Esophageal and Gastric Varices ; Female ; Gastritis ; Helicobacter pylori ; Hemorrhage ; Humans ; Male ; Pathology ; Pharynx ; Pyloric Antrum ; Stomach Ulcer ; Urease ; Vomiting

No abstract available.
Diet* ; Humans ; Immunoglobulin E* ; Incidence* ; Infant*

No abstract available.
Creatinine* ; Humans ; Infant, Newborn*

Herpes simplex esophagitis can occur in those with normal immune function, but is more often seen in those who are immunocompromised. In one series, 5 percent of post-kidney transplant recipients had herpes esophagitis. We experienced a case of herpes simplex esophagitis, following renal transplantation in a 9 year old male. He complained of epigastric pain, nausea and blood-tinged vomiting. Endoscopic examination showed volcano ulcer, mucosal friability and multiple confluent ulcers covered by whitish exudates on elevated margin in the middle and lower esophagus. Microscopic findings revealed multinucleated giant cells, margination of chromatin, intense nonspecific inflammation and strong positive for herpes simplex virus immunohistochemical staining. Esophageal lesions and symptoms improved after acyclovir therapy.
Acyclovir ; Child* ; Chromatin ; Esophagitis ; Esophagus ; Exudates and Transudates ; Giant Cells ; Herpes Simplex* ; Humans ; Inflammation ; Kidney Transplantation ; Male ; Nausea ; Simplexvirus* ; Transplantation ; Ulcer ; Vomiting

Astrovirus is frequently associated with diarrhea in children. It can not be readily isolated by cell culture, and an electronmicroscope is usually used for detection of this agent. Recently in 1995 a combined method of reverse transcription-polymerase chain reaction (RT-PCR) was designed for easier detection of astrovirus, which is based on the conserved sequence in 3'-end of genomes of the 7 known serotypes of human astrovirus. As of yet there has not been any report of astrovirus data in Korea using the RT-PCR methods. The purpose of this study was to detect astrovirus incidence, severity of symptoms, seasonal variation and coinfection rate with rotavirus in Korean children inpatients with diarrhea. Fecal specimens from 61 young children hospitalized with gasteroenteritis Korea from Jan. 1996 through Mar. 1997. They were examined for astroviurs infection by RT-PCR method. Results are as follows: 1. Astrovirus was detected at 9.8% (6/61) from fecal specimens of children with severe diarrhea by EIA using monoclonal antibody coated plates. 2. Astorvirus was detected at 29.5% (18/61) from fecal specimens of children with severe diarrhea by RT-PCR. 3. The age of the 18 children affected by astrovirus ranged from 2 monthes to 7 years with mean of 3.0 years. 4. Mean hospital stay of the 1S children was 6.1 days. 5. Five (27.8%) astrovirus RT-PCR positive strains were confirmed in November and in December, respectively out of 18 specimens in total. 6. Astrovirus coinfection with rotavirus type G1 was confirmed in 15/16 specimens (93.8%), and with type G2 was in 1/16 specimens (6.3%).
Cell Culture Techniques ; Child* ; Coinfection ; Conserved Sequence ; Diarrhea ; Feces* ; Genome ; Humans ; Incidence ; Inpatients ; Korea ; Length of Stay ; Mamastrovirus ; Polymerase Chain Reaction* ; Reverse Transcription* ; Rotavirus ; Seasons

Breastmilk provides the best optimal nutrition for infants, especially for the first few months of life. In breastmilk, there are innumerable immune protective and modulating factors. Also, the nutrients in breastmilk act as immune protective factors. The advantages of breastfeeding are not only for protection from infectious diseases, but also protection from some chronic disease, such as celiac disease, atopy, and obesity. A dose-response relationship of breastfeeding has been reported. For lifelong health, breastfeeding is the first step. In Korea, the majority of mothers obtain information about breastfeeding from internet searching, books and magazines. Physicians should actively and enthusiastically recommend breastfeeding and provide detailed advice and integral information about breastfeeding.
Breast Feeding ; Celiac Disease ; Chronic Disease ; Communicable Diseases ; Humans ; Infant ; Internet ; Korea ; Mothers ; Obesity ; Periodicals as Topic ; Resin Cements

Human rotavirus has now been established as the leading cause of gastroenteritis in young children worldwide. At least fourteen serotypes of group A rotavirus have been identified on the basis of antibody responses to major neutralizing glycoprotein, VP7 (G type for glycoprotein), present in the outer capsid of the virus. Serotype 1, 2, 3 and 4 are the most highly prevalent in human. In Korea, rotavirus is also the principal cause of severe nonbacterial diarrhea requiring hospitalization in infants and young children, which is commonly detected by EIA method. The epidemiology of rotavirus infection has been monitored by only serologic methods without electropherotyping in Korea. This study shows seasonal and age related variations .of rotavirus infection in Korea according to the genotype using the reverse transcription polymerase chain reaction (RT-PCR). Fecal specimens were obtained from 39 children hospitalized with acute watery diarrhea and gastroenteritis in Ewha Womans University MokDong Hospital in Seoul from Jan. to Dec. of 1996. All four (1, 2, 3, 4) major G serotypes were identified by amplification of segment of the gene for VP7 using RT-PCR. Rotavirus Gl 749 bp, G2 653 bp, G3 374 bp and G4 583bp were shown on 2.9 or 3.3% NuSieve agar gel. Results were as follows: 1) Rotavirus was detected at 53.8% (21/39) by EIA and 89.7% (35/39) by RT-PCR. 2) Serotype Gl, G2, G3, G4 when detected by RT-PCR accounted for 80.0% (28/35), 14.3% (5/35), 2.9% (1/35) and 2.9% (1/35), respectively. 3) Thirty five strains of rotavirus were detected at the frequency of 17.1% (6/35) in Oct., 20.0% (7/35) in Nov. and 20.0% (7/35) in Dec. 4) As for the age range, children affected by rotavirus were mostly under 1 years.
Agar ; Antibody Formation ; Capsid ; Child ; Child, Hospitalized* ; Diarrhea* ; Epidemiology ; Female ; Gastroenteritis ; Genotype* ; Glycoproteins ; Hospitalization ; Humans* ; Infant ; Korea ; Polymerase Chain Reaction* ; Reverse Transcription* ; Rotavirus Infections ; Rotavirus* ; Seasons ; Seoul

PURPOSE: To identify factors that influence serum zinc concentrations in children with acute gastroenteritis. METHODS: Thirty-two children under 5 years of age (15 boys and 17 girls) were selected randomly among those who visited to an pediatric emergency room of Ehwa Womans University Mokdong Hospital with acute gastroenteritis from May to August 2005. This study estimated the association between serum zinc concentrations and clinical, biochemical variables in patients with acute gastroenteritis. RESULTS: Serum zinc concentration was lower in febrile patients than afebrile patients with acute gastroenteritis (67.0+/-25.3 vs 85.5+/-14.2, p<0.05). It also was lower in patients with positive C-reactive protein (CRP) than those with negative CRP (63.9+/-25.4 vs 86.7+/-13.8, p<0.05). Serum zinc concentration was negatively correlated (r=-0.494, p<0.05) with CRP concentration, whereas positively correlated with hematocrit (r=0.370, p<0.05), total protein (r=0.474, p<0.05), and albumin (r=0.636, p<0.05). Twelve patients (37.5%) showed very low serum zinc concentration (<70 microgram/dL) without clinical symptoms of deficiency or growth retardation. Frequency of febrile illness or positive CRP is significantly greater in group with zinc <70 microgram/dL than the group with zinc > or =70 microgram/dL (91.7% vs 55%, p<0.05; 91.7% vs 40%, p<0.05, respectively). CONCLUSION: In patients with acute gastroenteritis, serum zinc concentration was influenced by various factors such as fever, CRP, and biochemical factors. For evaluating zinc status in the body. factors.
C-Reactive Protein ; Child* ; Emergency Service, Hospital ; Female ; Fever ; Gastroenteritis ; Hematocrit ; Humans ; Zinc*