No abstract available.
Nocardia Infections*

X-linked ichthyosis is a hereditary dermatosis characterized by large dark and thick scaly skin of trunk, extremities, scalp and neck. Rare manifested ocular signs include scales on lid and lashes, corneal opacity, lens opacity, and peripheral retinal granular hyperpigmentation. The authors experienced a case of diffuse punctate corneal opacities observed in the deep stroma or pre- Descemet's layer which developed in a 12-year old male patient who visited our clinic complaining symtoms of itching and dark thick scales on trunk, extremities, and scalp since at birth a.nd diagnosed as X-linked ichthyosis by clinical and histologic features.
Cataract ; Child ; Corneal Opacity* ; Extremities ; Humans ; Hyperpigmentation ; Ichthyosis* ; Male ; Neck ; Parturition ; Pruritus ; Retinaldehyde ; Scalp ; Skin ; Skin Diseases ; Weights and Measures

Choristomas are defined as benign congenital overgrowth of normal tissues in an abnormal location, which can contain lacrimal gland, muscle, cartilarge, adipose tissue, nerve, epidermal appendage. There are many reports about choristoma but cartilarge containing choristoma is very rare. We experienced a 20-year-old healthy male patient complaining of mass on limbus. The diagnosis was limbal dermoid. After tumor removal, histopathologically it was proved as complex choristoma. It contains not only muscular tissue, adipose tissue, neural tissue but also cartilarge. We report this case because of the rarity of cartilarge containing choristoma.
Adipose Tissue ; Choristoma* ; Dermoid Cyst ; Diagnosis ; Humans ; Lacrimal Apparatus ; Male ; Young Adult

The endoscopic sphincterotomy plays an important role in the treatment of common duct stones; however, with a sphincterotomy has the potential hazard of critical complications. Retroperitoneal duodenal perforation during the endoscopic sphincterotomy is a well-recognized complication causing retroperitoneal abscess, sepsis, and sometimes death. We experienced a patient who complained a severe abdominal pain with a febrile sensation after an endoscopic retrograde cholangiopancreatography with sphincterotomy. The diagnosis was delayed, but confirmed by the CT scan, and a duodenal diverticulization with T-tube drainage was performed. The patient was managed by using a duodenal diverticulization with T-tube drainage, but a conservative management is usually effective if the duodenal perforation is recognized immediately and occurs together with uninfected minimal soilage.
Abdominal Pain ; Abscess ; Cholangiopancreatography, Endoscopic Retrograde ; Diagnosis ; Drainage ; Humans ; Sensation ; Sepsis ; Sphincterotomy, Endoscopic* ; Tomography, X-Ray Computed

The polyglandular autoimmune syndrome designates the dysfunction of endocrine and nonendocrine system involving two or more organs on the basis of an autoimmune mechanism. The autoimmune nature of these diseases has been based on the presence of lymphocytic infiltration in the affected gland, organ specific autoantibodies in the serum, cellular immune defects and an association with the HLA DR/DQ genes or immune response genes. This syndrome is usually classified into three classes and their etiology or pathogenesis is still not completely understood. A 28-year-old woman developed vitiligo and insulin dependent diabetes mellitus during the treatment of Graves' disease with antithyroid drug. She had a tendency of spontaneous ketonemia and serum c-peptide levels were low(0.21, 0.16ng/mL: fasting and glucagon stimulated). Thyrotrophin binding inhibitor immunoglobulin and pancreas iIslet cell cytoplasmic antibody were positive. We report here a case of polyglandular autoimmune syndrome, type III manifesting Graves' disease, vitiligo, and insulin dependent diabetes mellitus.
Adult ; Autoantibodies ; Bone Diseases ; C-Peptide ; Cytoplasm ; Diabetes Mellitus ; Fasting ; Female ; Genes, MHC Class II ; Giant Cells ; Glucagon ; Granuloma ; Graves Disease ; Humans ; Immunoglobulins ; Insulin ; Ketosis ; Pancreas ; Pedigree ; Thyrotropin ; Vitiligo

No abstract available.
Teratoma*

Antinuclear antibody(ANA) and rheumatoid factor(RF) in the sera of 191 coal workers pneumoconiosis(CWP) patients, 65 healthy coal workers, and 52 non-mining controls were examined by the categories of CWP, age, duration of exposure, smoking and drinking habit. Indirect fluorescent antibody technique for ANA and latex agglutination method for RF were applied for detection. ANA was positive in 24.3% of CWP patients, 10.8% of healthy coal workers and 11.5% of non-mining controls. RF was positive in 36.5 % of CWP patients, 13.8 % of healthy coal workers and 9.6 % of non-mining controls.
Agglutination ; Anthracosis* ; Antibodies, Antinuclear* ; Coal* ; Drinking ; Fluorescent Antibody Technique, Indirect ; Humans ; Latex ; Rheumatoid Factor* ; Smoke ; Smoking

OBJECTIVE: Our purpose was to investigate the relationship between the levels of IL-6 and tumor necrosis factor-alpha in the peritoneal fluid(PF) of women with and without endometriosis and infertile women. Design: Prospective and case-control study. Setting: University hospital. Patients: Twenty-nine women with laparotomy or laparoscopic findings of minimal to severe endometriosis, and twenty-eight women with no visual evidence of pelvic endometriosis and with benign gynecologic disease. Main Outcome Measures: PF IL-6 and tumor necrosis factor-alpha levels were determined using commercial ELISA. IL-6 and tumor necrosis factor-alpha concentrations were compared among women with and without endometriosis, and with infertile and fertile women, and then also compared according the revised American Fertility Society classification. RESULTS: IL-6 and tumor necrosis factor-alpha concentrations were higher than in the PF of women with endometriosis than in matched normal controls. Cyclic variations in IL-6 concentrations were seen in PF from patients with endometriosis: the concentrations in the secretory phase were significantly higher than those in the proliferative phase. IL-6 concentrations were higher than in the PF among of infertile women than in fertile women. A significant correlation between PF IL-6 and tumor necrosis factor-alpha concentrations and endometriosis stage III and IV was noted. CONCLUSIONS: Increased PF levels of IL-6 and tumor necrosis factor-alpha in patients with endometriosis may be relate to endometriosis-associated infertility and to the pathogenesis of endometriosis suggesting that partially contribute to the disturbed immune regulation observed in patients with endometriosis.
Ascitic Fluid* ; Case-Control Studies ; Classification ; Endometriosis* ; Enzyme-Linked Immunosorbent Assay ; Female ; Fertility ; Genital Diseases, Female ; Humans ; Immunity, Cellular* ; Infertility ; Interleukin-6 ; Laparotomy ; Outcome Assessment (Health Care) ; Prospective Studies ; Tumor Necrosis Factor-alpha

Researchers have an ethical responsibility to report the results of research involving human subjects. Dissemination of results ensures that patient care is based on good science and that the field of medicine advances based on complete and accurate knowledge. However, current evidence suggests that publication is often neglected or substantially delayed, especially in the case of negative and inconclusive results. Researchers, editors and reviewers should value all high-quality research regardless of the conclusiveness of the results and ensure that all research involving human subjects is registered in a publicly accessible database.
Clinical Trials as Topic/*ethics ; *Ethics, Research ; Human Experimentation/*ethics ; Publishing/*ethics ; Republic of Korea ; *Research Report ; Research Subjects

In 1989, the Bethesda System (TBS) was introduced as an attempt to standardize cervical/vaginal reporting systems. TBS nomenclature was created for reporting cytologic diagnoses to replace the currently used Cervical Intraepithelial Neoplasia (CIN) and Papanicolaou Class System, which are deemed less reproducible. The name for preinvasive squamous lesions was changed to squamous intraepithelial lesion (SIL), subdivided into low-grade and high-grade types. TBS recommends a specific format for cytologic report, starting with explicit statement on the adequacy of the specimen, followed by general categorization and descriptive diagnosis. Pathologic and epidemiologic studies performed over last 10 years have provided evidence that human papillomavirus (HPV) plays a significant role in the development of cervical neoplasia. TBS corresponds not only to currently held views of the behavior of preinvasive lesions and their HPV distribution, but also to the current guidelines for clinical management.
Azathioprine* ; Body Fluids ; Cadherins ; Cervical Intraepithelial Neoplasia ; Diagnosis ; Epidemiologic Studies ; Humans ; Immunohistochemistry ; Nephritis* ; Nephrotic Syndrome* ; Purpura, Schoenlein-Henoch*