No abstract available.
Animals ; Binding Sites* ; Carbon Monoxide* ; Carbon* ; Rats* ; Serotonin*

No abstract available.
Hyperplasia*

No abstract available.
Electromyography* ; Hand* ; Humans ; Muscle Spasticity* ; Stroke*

PURPOSE: To analyze the characteristics of anatomical non-response to intravitreal bevacizumab (IVB) in patients with neovascular age-related macular degeneration (AMD). METHODS: Neovascular AMD patients who were treated with IVB were studied. A non-responder was defined as a patient whose eyes had no change in choroidal neovascularization (CNV) lesion size or fluorescein leakage and no change in foveal thickness (FT) after at least two administrations of IVB. Demographic findings and efficacy outcomes were compared between responders and non-responders based on patient gender, age, visual acuity (VA), FT, CNV lesion type, CNV lesion size, presence of serous retinal detachment (SRD), presence of pigment epithelial detachment (PED), PED size, and presence of sub-macular hemorrhage (SMH). RESULTS: Five patients (six eyes; 13.6%) were identified as non-responders to treatment with IVB. The mean age of the non-responder group (75.17 +/- 3.66 yers) was greater (p = 0.237) than that of the responder group (71.89 +/- 8.06 years), and the proportion of occult CNV (85.7% versus 55.3%, p = 0.375) was higher in the non-responder group, although there was no significant difference compared with that of the responder group. The PED size of the non-responder group (4.42 +/- 1.56 mm2) was significantly larger than that of the responder group (1.51 +/- 2.33 mm2, p = 0.001). CONCLUSIONS: The authors report a group of patients in AMD with poor treatment response to IVB. The PED size of the non-responder group was confirmed to be significantly larger than that of the responder group.
Antibodies, Monoclonal, Humanized ; Choroidal Neovascularization ; Eye ; Fluorescein ; Hemorrhage ; Humans ; Macular Degeneration ; Retinal Detachment ; Visual Acuity ; Bevacizumab

This erratum is being published to correct the printing error on page 286 of the article entitled 'Panton-Valentine leukocidin positive Staphylococcus aureus isolated from blood in Korea' by Kim JS, Park JS, Song W, Kim HS, Cho HC, Lee KM, Kim EC in Korean J Lab Med 2007;27:286-91. DOI 10.3343/kjlm. 2007.27.4.286 as follows. The heading of the right column of the Table 1 was misprinted as methicillin-resistant, so it should be corrected to methicillin-susceptible.
Adult ; Amino Acid Substitution ; Brain Neoplasms/radiotherapy/surgery ; Breast Neoplasms/diagnosis/radiotherapy/surgery ; Female ; *Genetic Counseling ; Genetic Predisposition to Disease ; *Germ-Line Mutation ; Humans ; Li-Fraumeni Syndrome/*diagnosis/genetics/therapy ; Mutation, Missense ; Pedigree ; Tumor Suppressor Protein p53/*genetics

The nineteen patients(20 eyes) of traumatic optic neuropathy were investigated to evaluate the effectiveness of high dose corticosteroid for the visual improvernent in the early treatment of this disease. The relationships between the affected region and visual improvement, the interval to treatment and final visual acuity, the initial visual acuity and final visual acuity were studied. 250mg of methylprednisolone was administered intravenously every 6 hours followed by tapering using oral prednisone. The optic canal decompression was performed in five patients suspected swelling of optic nerve or optic canal fracture revealed by orbital CT. It is difficult to know the relationships between the affected region and visual improvement, the interval to treatment and final visual acuity. The vision was improved in nine of eleven patients who had an initial visual acuity of above light perception, but in the two of nine patients who had an initial visual acuity of no light perception. The two of five patients treated with a combina tion of high dose corticosteroid and optic canal decompression showed improved visual function. In initial treatment of traumatic optic neuropathy, high dose corticosteroid was effective and combined optic canal decompression was helpful, if indicated.
Decompression ; Humans ; Methylprednisolone ; Optic Nerve ; Optic Nerve Injuries* ; Orbit ; Prednisone ; Visual Acuity