1.A clinical study in phenylketonuria.
Hye Kyeong NAM ; Jin Seop SHIM ; Dong Hwan LEE ; Sang Jhoo LEE ; Ki Weon CHA ; Jeong Bin YIM
Journal of the Korean Pediatric Society 1992;35(1):69-79
No abstract available.
Phenylketonurias*
2.Comparative studies of retentive forces in maxillary overdenture bar attachments.
Cha Young SON ; Chang Mo JEONG ; Young Chan JEON ; Jang Seop LIM ; Hee Chan JEONG
The Journal of Korean Academy of Prosthodontics 2005;43(5):650-661
STATEMENT OF PROBLEM: It could be hypothesised that attachments, which provide more retention against vertical and horizontal dislodgement, will be associated with more favorable parameters of oral function. PURPOSE: This study was to provide data of initial retentive force and retention loss of different bar attachment systems recommended for use with maxillary implant overdentures. MATERIAL AND METHOD: 4 implants were placed in the anterior region of edentulous maxilla, five different systems of bar attachment were fabricated as follows: cantilevered Hader bar using clips (Type 1), Hader bar using clips without cantilever (Type 2), Hader bar using clip and ERA attachment orange male (Type 3), Hader bar using clip and ERA attachment white male (Type 4), and Bar using magnets (Type 5). Each samples were placed in the universal testing machine for determination of retentive forces(at initial and after every 200 cycles up to 1,000 cycles). Results and Conclusion 1. Attachment type 1 showed the biggest initial retentive force followed by type 3, type 2, type 4, and lastly type 5( p<0.001). 2. After 1,000 cycles of repeated removals of attachments, significant loss of retentive forces was taken place except for attachment type 5. 3. After 1,000 cycles of repeated removals, the loss of retentive force between type 1 and type 2, which used Hader bar and clip attachments, was greater in type 1 that had wider clip formation. And between type 3 and type 4, which used ERA attachments, the loss of retentive force was greater in type 4 that had white male attached (p<0.001). 4. After 1,000 cycles of repeated removals, attachment type 3 showed the biggest retentive force followed by type 2, type 4, type 1 and lastly type. 5. There was no significant difference between attachment type 3 and 4, and type 4 and 1(p<0.001).
Citrus sinensis
;
Denture, Overlay*
;
Humans
;
Male
;
Maxilla
4.A Case of Duodenal Diverticulum Mimicking a Peripancreatic Abscess.
Sun Young KIM ; Jin Nam KIM ; Sun Ok KWON ; In Hye CHA ; Soo Hyung RYU ; You Sun KIM ; Jeong Seop MOON
Korean Journal of Medicine 2013;84(2):249-253
The duodenum is the second most common site, after the colon, of diverticuli in the alimentary tract. Although most patients with duodenal diverticuli are asymptomatic, previous studies have demonstrated a possible association between duodenal diverticuli and choledocholithiasis and pancreatitis. In addition, duodenal diverticuli mimicking periampullary tumors and cystic neoplasms of the pancreas have been reported. We report a case of a duodenal diverticulum that mimicked a peripancreatic abscess. A 65-year-old woman was admitted for epigastric pain and vomiting. Abdominal CT confirmed the diagnosis of acute pancreatitis. Follow-up abdominal CT performed for a sustained fever revealed several newly developed peripancreatic abscesses. Most of the abscesses were drained percutaneously, but those around the uncinate process seldom respond to treatment. This patient was confirmed to have a duodenal diverticulum by endoscopy and duodenography. Duodenal diverticuli must be considered in a differential diagnosis of peripancreatic abscesses.
Abscess
;
Choledocholithiasis
;
Colon
;
Diagnosis, Differential
;
Diverticulum
;
Duodenum
;
Endoscopy
;
Female
;
Fever
;
Follow-Up Studies
;
Humans
;
Pancreas
;
Pancreatitis
;
Vomiting
5.A Case of EBV-associated Hemophagocytic Lymphohistiocytosis with Seizure and Loss of Consciousness.
Hye Cheon JEONG ; Deok Soo KIM ; Won Seop KIM ; Sang Hoon CHA ; Il Heon BAE ; Kyeong Seob SHIN ; Bo Ra SON ; Hyeon Jin PARK
Journal of the Korean Child Neurology Society 2002;10(2):325-332
Hemophagocytic lymphohistiocytosis(HLH) is a rare and fatal disorder in children. Persistent fever, hepatosplenomegaly and pancytopenia are observed in the most cases with the characteristic change of serum triglyceride, fibrinogen, ferritin and LDH level. CNS manifestation were developed in 50-70% of HLH. 20% of cases revealed seizure and irritability at diagnosis. Abnormalities on brain imaging, such as diffuse white matter abnormalities and necrotic area with parenchymal volume loss appeared to roughly parallel the severity of clinical manifestations. In HLH, EBV is the major triggering agent inducing hemophagocytosis as well as the fulminant course of disease. Many cases of EBV-HLH had monoclonal origin and respond well to etoposide-containing regimens. Early induction of an etoposide based regimen is critical factor in securing long-term survival in patients with EBV-HLH. We report a case that 13 year-old female patient with seizure and loss of consciousness was diagnosed as EBV-HLH and treated with protocol HLH-94 consistd of etoposide, dexamethasone, cyclosporin.
Adolescent
;
Central Nervous System
;
Child
;
Cyclosporine
;
Dexamethasone
;
Diagnosis
;
Etoposide
;
Female
;
Ferritins
;
Fever
;
Fibrinogen
;
Herpesvirus 4, Human
;
Humans
;
Lymphohistiocytosis, Hemophagocytic*
;
Neuroimaging
;
Pancytopenia
;
Seizures*
;
Triglycerides
;
Unconsciousness*
6.Guidelines for Bowel Preparation before Video Capsule Endoscopy.
Hyun Joo SONG ; Jeong Seop MOON ; Jae Hyuk DO ; In Hye CHA ; Chang Hun YANG ; Myung Gyu CHOI ; Yoon Tae JEEN ; Hyun Jung KIM
Clinical Endoscopy 2013;46(2):147-154
The preparation for video capsule endoscopy (VCE) of the bowel suggested by manufacturers of capsule endoscopy systems consists only of a clear liquid diet and an 8-hour fast. While there is evidence for a benefit from bowel preparation for VCE, so far there is no domestic consensus on the preparation regimen in Korea. Therefore, we performed this study to recommend guidelines for bowel preparation before VCE. The guidelines on VCE were developed by the Korean Gut Image Study Group, part of the Korean Society of Gastrointestinal Endoscopy. Four key questions were selected. According to our guidelines, bowel preparation with polyethylene glycol (PEG) solution enhances small bowel visualization quality (SBVQ) and diagnostic yield (DY), but it has no effect on cecal completion rate (CR). Bowel preparation with 2 L of PEG solution is similar to that with 4 L of PEG in terms of the SBVQ, DY, and CR of VCE. Bowel preparation with fasting or PEG solution combined with simethicone enhances the SBVQ, but it does not affect the CR of VCE. Bowel preparation with prokinetics does not enhance the SBVQ, DY, or CR of VCE.
Capsule Endoscopy
;
Consensus
;
Diet
;
Endoscopy, Gastrointestinal
;
Fasting
;
Korea
;
Polyethylene Glycols
;
Simethicone
7.Endoscopist Specialty Is Associated with High-Quality Endoscopy in Korea.
Jae Myung CHA ; Dong Soo HAN ; Hang Lack LEE ; Young Ho KIM ; Il Kwun CHUNG ; Hyun Soo KIM ; Jeong Seop MOON ; Yu Kyung CHO
Yonsei Medical Journal 2012;53(2):310-317
PURPOSE: The present study was aimed to determine whether endoscopist specialty is associated with high-quality endoscopy. MATERIALS AND METHODS: We prospectively collected endoscopy quality related data based on the Endoscopy Quality Rating Scale (EQRS) of 277 endoscopy units in a hospital setting from the National Cancer Screening Program of Korea in 2009. Gastroenterology medical professors (n=154) from university hospitals visited each endoscopy unit and graded the unit according to the EQRS. The scores from the EQRS were analyzed and compared in relation to endoscopy training during residency and endoscopy subspecialist certification. RESULTS: After excluding data from 3 endoscopy units, EQRS data from 274 endoscopy units were analyzed: 263 esophagogastroduodenoscopy (EGD) screening units and 90 colonoscopy screening units. There were no significant differences in the scores of EQRS with respect to endoscopy training during residency (p=no significance), except for scores of EGDs for "Facility and Equipment" (p=0.030). However, EQRS scores were significantly higher in the endoscopy units where endoscopy subspecialists performed the endoscopies than those where Endoscopy Subspecialists did not perform the endoscopies (p<0.05, except p=0.08 for the "Process" criteria of EGD). CONCLUSION: Endoscopist specialty is an important determinant of high-quality endoscopy in Korea.
Endoscopy/*standards
;
Endoscopy, Digestive System/standards
;
Humans
;
Korea
;
Medicine/*standards
;
Physicians/*standards
8.Metastatic Common Bile Duct Cancer from Pulmonary Adenocarcinoma Presenting as Obstructive Jaundice.
In Hye CHA ; Jin Nam KIM ; You Sun KIM ; Soo Hyung RYU ; Jeong Seop MOON ; Hye Kyung LEE
The Korean Journal of Gastroenterology 2013;61(1):50-53
We report an extremely rare case of metastatic common bile duct cancer from pulmonary adenocarcinoma presenting as obstructive jaundice. The patient was a 76-year-old male, who presented with generalized weakness and right upper quadrant pain. Plain chest X-ray noted multiple small nodules in both lung fields. Abdominal computed tomography scan showed a stricture of the mid common bile duct along with ductal wall enhancement. Endoscopic retrograde cholangiography revealed a concentric, abrupt narrowing of the mid-common bile duct suggestive of primary bile duct cancer. However, pathology comfirmed metastatic common bile duct cancer arising from pulmonary adenocarcinoma with immunohistochemical study with thyroid transcriptional factor-1 (TTF-1).
Adenocarcinoma/*diagnosis/pathology/radiography
;
Aged
;
Brain Neoplasms/radiography/secondary
;
Bronchoscopy
;
Cholangiopancreatography, Endoscopic Retrograde
;
Common Bile Duct Neoplasms/*diagnosis/secondary
;
DNA-Binding Proteins/metabolism
;
Humans
;
Immunohistochemistry
;
Jaundice, Obstructive/*etiology
;
Lung Neoplasms/*diagnosis/pathology/radiography
;
Male
;
Positron-Emission Tomography
;
Tomography, X-Ray Computed
9.Bile Flow Phantom Model and Animal Bile Duct Dilation Model for Evaluating Biliary Plastic Stents with Advanced Hydrophilic Coating.
Chang Il KWON ; Gwangil KIM ; Seok JEONG ; Won Seop LEE ; Don Haeng LEE ; Kwang Hyun KO ; Sung Pyo HONG ; Ki Baik HAHM
Gut and Liver 2016;10(4):632-641
BACKGROUND/AIMS: The efforts to improve biliary plastic stents (PSs) for decreasing biofilm formation and overcome short patency time have been continued. The aim of this study is to evaluate the effect of advanced hydrophilic coating for patency and biodurability of PS. METHODS: Using an in vitro bile flow phantom model, we compared patency between prototype PS with hydrophilic coating (PS+HC) and prototype PS without hydrophilic coating (PS-HC). We performed an analysis of the degree of luminal narrowing by microscopic examination. Using an in vivo swine bile duct dilation model made by endoscopic papillary closure and stent insertion, we evaluated biodurability of hydrophilic coating. RESULTS: In the phantom model, PS+HC showed less biofilm formation and luminal narrowing than PS-HC at 8 weeks (p<0.05). A total of 31 stents were inserted into the dilated bile duct of seven swine models, and 24 stents were successfully retrieved 8 weeks later. There was no statistical difference of stent patency between the polyethylene PS+HC and the polyurethane PS+HC. The biodurability of hydrophilic coating was sustained up to 8 weeks, when assessing the coating layer by scanning electron microscopy examination. CONCLUSIONS: Advanced hydrophilic coating technology may extend the patency of PS compared to uncoated PS.
Animals*
;
Bile Ducts*
;
Bile*
;
Biofilms
;
In Vitro Techniques
;
Microscopy, Electron, Scanning
;
Phenobarbital
;
Plastics*
;
Polyethylene
;
Polyurethanes
;
Stents*
;
Swine
10.Comparison of fentanyl and sufentanil added to 0.5% hyperbaric bupivacaine for spinal anesthesia in patients undergoing cesarean section.
Jung Hyang LEE ; Kum Hee CHUNG ; Jong Yun LEE ; Duk Hee CHUN ; Hyeon Jeong YANG ; Tong Kyun KO ; Wan Seop YUN
Korean Journal of Anesthesiology 2011;60(2):103-108
BACKGROUND: Subarachnoid block is widely used for cesarean section due to the rapid induction, the complete analgesia, the low failure rate and the prevention of aspiration pneumonia. The addition of intrathecal opioids to local anesthetics seems to improve the quality of analgesia & prolong the duration of analgesia. Therefore we compared the effects of fentanyl 20 microg and sufentanil 2.5 microg, which were added to intrathecal hyperbaric bupivacaine. METHODS: Seventy two healthy term parturients were randomly divided into three groups: Group C (control), Group F (fentanyl 20 microg) and Group S (sufentanil 2.5 microg). In every group, 0.5% heavy bupivacaine was added according to the adjusted dose regimen by Harten et al. We observed the maximal level of the sensory block and motor block, the quality of intraoperative analgesia, the duration of effective analgesia and the side effects. RESULTS: There were significant differences between the control and the fentanyl 20 microg and sufentanil 2.5 microg groups for the degree of muscle relaxation, the quality of intraoperative analgesia, the maximal sedation level and the duration of effective analgesia. The frequencies of side effects such as nausea and pruritis in the opioid groups were higher than those in the control group. But there were no differences between fentanyl 20 microg and sufentanil 2.5 microg for the frequencies of nausea and pruritis. CONCLUSIONS: The addition of fentanyl 20 microg or sufentanil 2.5 microg for spinal anesthesia provides adequate intraoperative analgesia without significant adverse effects on the mother and neonate.
Analgesia
;
Analgesics, Opioid
;
Anesthesia, Spinal
;
Anesthetics, Local
;
Bupivacaine
;
Cesarean Section
;
Female
;
Fentanyl
;
Humans
;
Infant, Newborn
;
Mothers
;
Muscle Relaxation
;
Nausea
;
Pneumonia, Aspiration
;
Pregnancy
;
Pruritus
;
Sufentanil