No abstract available.

No abstract available.
Head* ; Neck*

No abstract available.
Diagnosis* ; Tuberculosis, Lymph Node*

No abstract available.
Carotid Artery, Common* ; Rupture*

This study was performed to investigate associations between serum alpha(1)-antitrypsin(AAT) concentration and radiological categories of coal workers' pneumoconlosis(CWP), between AAT concentration and pulmonary complications such as tuberculosis and emphysema, and to study associations between AAT concentration and FEV(1.0)% in CWP patients, We classified 254 CWP patients in D Hospital into categories of small opacity profusion. And we selected 86 subjects by with or without emphysematous finding in each categories by proportional stratified sampling method. Semm AAT concentrations were quantkated by single radial immunodiffusion method, and the findings of chest radiographs were evaluated by radilogist. The results were as follows: 1. Serum AAT concentrations were not significantly different among groups of radiological categories of small opacities. 2. Complication of emphysema was associated with smoking habits sigmficantlyl(chi square=12.16, p<0,01). And AAT concentraLion was higher in smokers and ex-smokers than in non-smokers. Serum AAT concentration was significantly higher in the cases with emphysema than in the cdses without emphybema{p<0.01). 3. Serum AAT concentration of the group with active pulmonary tuberculosis was significantly higher than with inactive or without: pulmonary tuberculosis group(p<0.1). 4. Serum AAT concentration of the group with low FEV(1.0)% was significantly higher than with high or normal group(p<0.05).
Anthracosis ; Coal* ; Emphysema ; Humans ; Immunodiffusion ; Pneumoconiosis* ; Radiography, Thoracic ; Smoke ; Smoking ; Tuberculosis ; Tuberculosis, Pulmonary

The external laryngeal trauma is a rare but clinically important injury. The blunt trauma is more common than penetrating one. As other trauma, early suspicion and accurate diagnosis of acute laryngeal and tracheal injuries are crucial. If the airway obstruction is impending, secure airway should be made before diagnosis or treatment. The computed tomography scans play an important role in diagnosis and combined cervical esophageal injury should be evaluated. Proper restoration of the laryngeal framework with appropriately timed open reduction and internal fixation is critical for optimal recovery of the airway, voice, and swallowing.
Airway Obstruction ; Deglutition ; Diagnosis ; Larynx ; Trachea ; Voice

PURPOSE: Spatial hearing refers to the ability to understand speech and identify sounds in various environments. We assessed the validity of the Korean version of the Spatial Hearing Questionnaire (K-SHQ). MATERIALS AND METHODS: We performed forward translation of the original English SHQ to Korean and backward translation from the Korean to English. Forty-eight patients who were able to read and understand Korean and received a score of 24 or higher on the Mini-Mental Status Examination were included in the study. Patients underwent pure tone audiometry (PTA) using a standard protocol and completed the K-SHQ. Internal consistency was evaluated using Cronbach's alpha, and factor analysis was performed to prove reliability. Construct validity was tested by comparing K-SHQ scores from patients with normal hearing to those with hearing impairment. Scores were compared between subjects with unilateral or bilateral hearing loss and between symmetrical and asymmetrical hearing impairment. RESULTS: Cronbach's alpha showed good internal consistency (0.982). Two factors were identified by factor analysis: There was a significant difference in K-SHQ scores for patients with normal hearing compared to those with hearing impairment. Patients with asymmetric hearing impairment had higher K-SHQ scores than those with symmetric hearing impairment. This is related to a lower threshold of PTA in the better ear of subjects. The hearing ability of the better ear is correlated with K-SHQ score. CONCLUSION: The K-SHQ is a reliable and valid tool with which to assess spatial hearing in patients who speak and read Korean. K-SHQ score reflects the severity and symmetry of hearing impairment.
Audiometry ; Ear ; Hearing Loss* ; Hearing Loss, Bilateral ; Hearing* ; Humans ; Sound Localization

A case of cervical chordoma diagnosed by fine needle aspiration is discussed. A 41year-old male was admitted due to dyspnea on neck flexion. Radiologic image revealed a retrotracheal superior mediastinal solid mass. Aspiration cytology showed many clusters of oval or large polygonal cells having abundant eosinophilic or bubbly cytoplasm in an amorphous blue-gray mucoid background. The nuclei were round and showed size variation, coarse granular chromatin, and indistinct nucleoli. Some cells contained brown granular pigments in the cytoplasm. Mitoses were rarely found. The cytoplasm was strongly positive for PAS stain. Immunohistochemical stains using cell block revealed positive reaction for cytokerain, EMA, vimentin, and S-100 protein. The confirmative diagnosis was made by following excisional biopsy. Electron microscopic study revealed large pools of intracytoplasmic glycogen and microfilaments. This is the first case of cervical chordoma diagnosed by aspiration cytology to our knowledge in Korean literature.
Actin Cytoskeleton ; Biopsy ; Biopsy, Fine-Needle* ; Chordoma* ; Chromatin ; Coloring Agents ; Cytoplasm ; Diagnosis ; Dyspnea ; Eosinophils ; Glycogen ; Humans ; Male ; Mitosis ; Neck ; S100 Proteins ; Vimentin

Sinonasal teratocarcinosarcoma is extremely invasive malignant tumor that has a histological characteristic of having both more than one epithelial and mesothelial tissue components. It is a rare cancer of having less than 50 cases reported until now and domestically. This case presents a 51 year-old male who had nasal stuffiness for 2 months. A mass was noticed in his right nasal cavity, and histopathologic findings revealed the mass as a teratocarcinosarcoma. Computed tomography and magnetic resonance imaging showed that the mass originated from right nasal septum and did not invade the sinuses and that it was touching the inferior turbinate. No cervical lymph node metastasis was observed (T2N0M0, Stage II). Wide excision of the mass was performed, and no invasion in the resection margin was confirmed. Radiotherapy was performed postoperatively. Currently, the patient has been followed up on a regular basis for 28 months. Thus, the authors present a report of very rare sinonasal teratocarcinosarcoma.
Carcinosarcoma ; Humans ; Lymph Nodes ; Magnetic Resonance Imaging ; Male ; Nasal Cavity ; Nasal Septum ; Neoplasm Metastasis ; Nose Neoplasms ; Teratoma ; Turbinates

BACKGROUND: ndothelin-1(ET1) has been reported about it's versatile pharmagological and physiological influences to airway calibre. Some investigators suggested that ET1 exisit in the nasal mucosa, and may play a part in the exaggerated symptoms of asthma and in controlling the nasal mucosal physiology. OBJECTIVES: In order to clarify the alterations of expression of ET1 in the pathologic nasal mucosa, we investigated the distribution of ET1 by immunohistochemistry at the allergic rhinitis mucosa and the polyp tissues. MATERIALS AND METHODS: The mucosal specimens were obtained from the inferior turbinate of normal persons(n=5) and from patients with allergic rhinitis(n=10), and the polyps from the lateral nasal wall of non-allergic patients(n=10). The immunoreactivity of the ET1 was evaluated by the immunohistochemical stainig with the anti-ET1 monoclonal antibody. RESULTS: The immunoreactivity of ET1 could be observed weakely in the epithelium, in the vascular endotheluim, and in the submucosal gland. But the feature was not constant and showed no statistical significance in each group. On the other hand, strong positive immunoreactivity was noted in the cytoplasm of the granulated large cells and bilobed nuclear leukocytes in the submucosa. These cells were proved to be the mast cells and the eosinophils respectively by means of the toluidine blue and the H & E staining. CONCLUSION: These findings would be reasonable to suggested that the ET1 existed in the mast cells and the eosinophils as like cytokines, and the ET1 activity may be affected by the quantity of these cells in allergic rhinitis or nasal polyps.
Asthma ; Cytokines ; Cytoplasm ; Endothelin-1* ; Eosinophils ; Epithelium ; Hand ; Humans ; Immunohistochemistry ; Leukocytes ; Mast Cells ; Mucous Membrane ; Nasal Mucosa* ; Nasal Polyps ; Physiology ; Polyps ; Research Personnel ; Rhinitis ; Tolonium Chloride ; Turbinates