1.A Case of Hydranencephaly Caused by Internal Carotid Artery Stenosis: Diagnosis with Doppler Sonogram.
Seong Woo ROH ; Seong Sook JEON ; Son Sang SEO ; Jeong Mi KWON
Journal of the Korean Society of Neonatology 1998;5(1):81-85
Hydranencephaly is congenital absence of the cerebral hemispheres which are replaced by a large fluid-filled cavity. The brain stem and basal ganglia are well formed and rudiments of frontal k occipital cortex may be present. We experienced a case of hydranencephaly caused by both internal carotid artery stenosis. We diagnosed it through the brain CT sonogram and doppler sonogram. A brief review of the related literatures was made.
Basal Ganglia
;
Brain
;
Brain Stem
;
Carotid Artery, Internal*
;
Carotid Stenosis*
;
Cerebrum
;
Hydranencephaly*
2.Effects of Blending Oil of Lavender and Thyme on Oxidative Stress, Immunity, and Skin Condition in Atopic Dermatitis Induced Mice.
Journal of Korean Academy of Nursing 2015;45(3):367-377
PURPOSE: The purpose of this study was to evaluate the effects of essential oil on oxidative stress, immunity, and skin condition in atopic dermatitis (AD) induced mice. METHODS: This study was a 3x3 factorial design. Factors were oil type (Lavender, Thyme, and 2:1 mixture of lavender and thyme oil [blending oil]) and treatment period (0 day, 7 days, and 21 days). The samples were 45 mice with AD and randomly assigned to nine groups of five mice per group. The dependent variables such as superoxide radical, IgE, degranulated mast cells, and epidermal thickness were measured. Data were collected from February to April in 2014. Descriptive statistics, One-way ANOVA, Two-way ANOVA, and Tukey's HSD test were performed using the SPSS WIN 20.0 program. RESULTS: Dependent variables were not statistically significantly different by the three oil types (p >.05). Essential oils such as lavender, thyme, and blending oil were all effective in reducing AD symptoms and especially 2:1 blending oil were most effective. There were statistically significant differences by the three treatment periods in all dependent variables (p <.001). There were statistically significant interactions between oil types and treatment periods in all dependent variables (p <.01). For decreasing superoxide radical, degranulated mast cells, and epidermal thickness, 2:1 mixed oil should be applied for at least 21 days. Otherwise to reduce IgE, 2:1 mixed oil should be used for at least 7 days. CONCLUSION: These findings provide bases for developing effective interventions for AD patients to manage their AD symptoms.
Animals
;
Dermatitis, Atopic/chemically induced/*drug therapy/pathology
;
Disease Models, Animal
;
*Immunity/drug effects
;
Immunoglobulin E/blood
;
Lavandula/*chemistry/metabolism
;
Mast Cells/cytology/metabolism
;
Mice
;
Oils, Volatile/chemistry/pharmacology/therapeutic use
;
*Oxidative Stress/drug effects
;
Picryl Chloride/toxicity
;
Plant Oils/chemistry/pharmacology/*therapeutic use
;
Singlet Oxygen/metabolism
;
Skin/drug effects/pathology
;
Thymus Plant/*chemistry/metabolism
3.The Genotypes of Helicobacter pylori, Gastric Epithelial Cell Proliferation and Apoptosis in Children.
Ji Ah JUNG ; Mi Ae LEE ; Jeong Wan SEO
Korean Journal of Pediatric Gastroenterology and Nutrition 2003;6(1):1-9
PURPOSE: To investigate the relation of the gastric epithelial cell proliferation, apoptosis and genotypes of H. pylori in children. METHODS: Histologic grading by updated Sydney system, PCNA immunostaining, TUNEL method and the genotypes (cagA, picB and iceA) by PCR were performed in H. pylori positive (N=20) and negative (N=20) gastric biopsy specimens. RESULTS: PCNA index was significantly different between H. pylori positive children (77.4+/-13.12) and H. pylori negative children (52.3+/-12.20) (p=0.000). There were positive correlations between PCNA index and H. pylori density (r=0.624, p=0.000), polymorphonuclear neutrophil activity (r=0.460, p=0.005) and chronic inflammation (r=0.433, p=0.009). Apoptosis index of H. pylori positive children (0.70+/-0.411) was significantly higher than of H. pylori negative children (0.14+/-0.201) (p=0.000). Positive correlations between apoptosis index and H. pylori density (r=0.691, p=0.000), polymorphonuclear neutrophil activity (r=0.585, p=0.000) and chronic inflammation (r=0.535, p=0.001) were noted. As PCNA index increased, apoptosis index significantly increased (r=0.527, p=0.001). The positive rates of genotypes were cagA 90%, picB 75%, iceA1 60% and iceA2 15%, respectively. There were no significant correlations between the status of the genotypes and PCNA index, apoptosis index, the endoscopic findings and the histologic findings. CONCLUSION: PCNA index and apoptosis index in H. pylori positive children were higher than in H. pylori negative children but were not related to H. pylori genotypes. This study suggested that correlatively increased gastric epithelial cell proliferation and apoptosis are important to pathogenesis of H. pylori infection in children.
Apoptosis*
;
Biopsy
;
Child*
;
Epithelial Cells*
;
Genotype*
;
Helicobacter pylori*
;
Helicobacter*
;
Humans
;
In Situ Nick-End Labeling
;
Inflammation
;
Neutrophils
;
Polymerase Chain Reaction
;
Proliferating Cell Nuclear Antigen
4.Erratum: A U-shaped Association between Body Mass Index and Psychological Distress on the Multiphasic Personality Inventory: Retrospective Cross-sectional Analysis of 19-year-old Men in Korea.
Taehyun KIM ; Jung Jun KIM ; Mi Yeon KIM ; Shin Kyoung KIM ; Sungwon ROH ; Jeong Seok SEO
Journal of Korean Medical Science 2015;30(10):1537-1537
One author's affiliation is misspelled in original article.
5.Excision of Hemangioma and Sculpturing of the Lip using a CO2 Laser.
Seung Lee SEO ; Kyu Kwang WHANG ; Mi Ae LEE ; Jeong Hee HAHM
Korean Journal of Dermatology 1998;36(3):441-445
BACKGROUND: Massive bleeding, inability to identify important landmarks and structures, and necessity for a blood transfusion have been the usual problems of hemangioma excision. OBJECTIVE: We introduce a CO2 laser excision technique as a surgical method for the treatment of hemangioma of the lips and demonstrate its benefits. METHODS: In 4 patients with nevus flammeus of hemiface and accompanying hemangioma of the lips, excision of the hemangioma was performed using a focused beam from a CO2 laser under local anesthesia. RESULTS: Excellent to good results were achieved with minimal blood losses in all patients. No or minimal post-operative pain and edema and no significant complications were observed. CONCLUSION:The CO2 laser excision technique is recommended since it renders less textural change, greater volume reduction, hemostasis and an overall good cosmetic outcome than defocused modes or conventional scalpel surgery.
Anesthesia, Local
;
Blood Transfusion
;
Edema
;
Hemangioma*
;
Hemorrhage
;
Hemostasis
;
Humans
;
Lasers, Gas*
;
Lip*
;
Port-Wine Stain
6.Analysis of Recent Four Years' Cross-Matching Tests of One Commercial Laboratory.
Dong Hee SEO ; Mi Young PARK ; Jeong Ryull KWAK
Journal of Laboratory Medicine and Quality Assurance 2016;38(4):249-252
The cross-matching test, an essential pre-transfusion test, is usually performed using only a segment of a blood bag and a recipient's blood sample at a commercial laboratory. We analyzed cross-matching test results obtained at LabGenomics laboratory, client of which were mainly small- and medium-sized medical clinics. Data for a total of 12,902 cross-matching tests referred from January 2012 to December 2015 were analyzed for incompatibility in the results and trends based on the distribution of medical clinics. Medical clinics were categorized as nursing home, obstetrics and gynecology, plastic surgery, dental clinic, orthopedic surgery, and others. Incompatible results were observed for 35 cases (1.09%) in 2012, 22 cases (0.68%) in 2013, 31 cases (1.02%) in 2014, and 41 cases (1.20%) in 2015. Overall, 55.4% of referrals came from a nursing home, 6.4% from obstetrics and gynecology, 4.4% from plastic surgery, 20.0% from dental clinic, 5.9 % from orthopedic surgery, and 7.9% from others. Further studies are required to evaluate the efficacy of cross-matching test results and its relationship with transfusion requirements.
Dental Clinics
;
Gynecology
;
Nursing Homes
;
Obstetrics
;
Orthopedics
;
Referral and Consultation
;
Surgery, Plastic
7.A Study on the Verification of the Profile of Seo's Elderly Stress Scale (SESS).
Hyun Mi SEO ; Su Jeong YU ; Yang Sook HAH
Journal of Korean Academy of Nursing 2001;31(1):94-106
The purpose of this study was to verify the use of Seo's Elderly Stress Scale (SESS), which was developed in 1996. Through the modified tool, it is possible to examine the stress of Korean elders and to contribute to the welfare of them. The subjects were 350 elders over 65 years old who live in Seoul, Kwang-Ju, Yang-Ju Gun Kyung-ki Do, Ui-Jong Bu, and Young-Am Kun, Jeun-Ra Nam Do. the data of 331 elders (94%) were analyzed. Data were collected between January and March in 1996 and analyzed using the SPSS Win 8.0. The result are as follows: 1. Items with low correlation with the total items were removed. So 27 items were removed and 37 items remained. This 37 items were death in the family and/or close friends, family member's behavior not meeting expectations, marriage of daughter, marriage of son, friction with daughter- in-law, argument among children, children refuse to live with parent, children leaving home, sex injury or accident, in frequest visits from children and grandchildren, providing care for your daughter or daughter-in-law post-partum, decrease in decision making and authority in home, Lunar new year and the harvest featival, house sitting, working in the house, performing a sacrificial rite, missed birthday, not living with the eldest son, decreased eyesight, decreased strength, decreased memory, sleep pattern changes, thoughts about death, loneliness, decreased hearing, change of dental condition, change in your diet or eating style, difficulty in self care, moving because of disease or aging, argument with friend or neighbour, travel, dealing with the procedure of heritage, loss of money or property, not enough pocket money, hearing on elderly neglect in television or radio, hope of going home and ignorant from others. 2. Overlapped items were discussed by colleagues and were modified. 'marriage of daughter' and 'marriage of son' were modified in 'marriage of children'. 'self injury or accidents' and 'family accidents' were modified in to self or family accidents. 3. Factor analysis was done in order to identify validity and three factors were obtained from the result. The first factor familial relation area, included 17 items. The second factor, physical area, included 9 items. The third factor, psycho-socio-economic area, included 9 items. Cronbach coefficient alpha for the 35 items was .923. 4. Pearson's correlation was .704 between SESS and SOS (Symptoms of Stress) in order to confirm construct validity. Based on the result, the following is suggested; 1. The modified SESS needs to be reverified with elder. 2. Korean elder's health promotion can be made by development of stress intervention which was accurately measured with SESS.
Aged*
;
Aging
;
Child
;
Decision Making
;
Diet
;
Eating
;
Factor Analysis, Statistical
;
Friction
;
Friends
;
Gwangju
;
Gyeonggi-do
;
Health Promotion
;
Hearing
;
Hope
;
Humans
;
Loneliness
;
Marriage
;
Memory
;
Nuclear Family
;
Parents
;
Self Care
;
Seoul
;
Television
8.A Case of Vibrio alginolyticus Isolated from Otorrhea of Chronic Otitis Media.
Yoon Jeong DOH ; Mi Hyang KIM ; Eun Seo KIM
Korean Journal of Infectious Diseases 1997;29(2):153-157
Vibrio alginolyticus is a microorganism of marine environment that occasionally occurs as a human pathogen. We isolated V. alginolyticus from a patient with otitis media. A 37-year-old man had been exposed to seawater one month before admission. The isolate showed typical biochemical and characteristics of this organism such as positive Voges-Proskauer reaction, fermentation of sucrose, growth on 10% sodium chloride media. In vitro susceptibility test shows the isolate was resistant to ampicillin and carbenicillin, but was susceptible to other antimicrobial agents. The patient improved with ciprofloxacin and ofloxacin therapy.
Adult
;
Ampicillin
;
Anti-Infective Agents
;
Carbenicillin
;
Ciprofloxacin
;
Fermentation
;
Humans
;
Ofloxacin
;
Otitis Media*
;
Otitis*
;
Seawater
;
Sodium Chloride
;
Sucrose
;
Vibrio alginolyticus*
;
Vibrio*
9.A Clinical Observation of Congenital Syphilis.
Soo Mi BAEK ; Eun Chin MOON ; Ock Seung JEONG ; Son Sang SEO
Journal of the Korean Pediatric Society 1990;33(10):1326-1332
No abstract available.
Syphilis, Congenital*
10.A Study of Clinical Features and Radiological Examination Evaluating Combined Vascular Diseases of Stasis Dermatitis
Seo Mi Gon JEONG ; Chi Yeon KIM
Korean Journal of Dermatology 2021;59(9):669-675
Background:
Stasis dermatitis is an inflammatory skin disease that occurs in the lower legs of patients with chronic venous insufficiency; however, data on combined vascular disease and stasis dermatitis are limited.
Objective:
This study aimed to evaluate the clinical features of patients with stasis dermatitis and combined vascular diseases.
Methods:
We retrospectively reviewed the clinical features and combined vascular diseases of 37 patients clinically diagnosed with stasis dermatitis who visited the dermatology department from January 2017 to December 2020.
Results:
The average age of occurrence was 59.5 years, and the average duration of the disease was 3.2 years. Stasis dermatitis was more likely to occur in women than in men and more often in both lower legs. The major clinical features were erythematous patches. Asymptomatic symptoms were most common, followed by itching and tenderness. To evaluate vascular diseases, ultrasonography, venography computed tomography (CT), and angiography CT were performed. The most common combined vascular diseases were deep vein thrombosis, followed by varicose vein and thrombophlebitis. Most cases were treated with topical steroids and antihistamines, and anticoagulants/ antiplatelet agents were used to treat vascular diseases.
Conclusion
Stasis dermatitis is mainly associated with venous dysfunction in the lower legs. Early diagnosis and fundamental treatment of combined vascular diseases by evaluating vascular function in patients suspected of stasis dermatitis are important. This study will provide dermatologists with significant data on the clinical features of stasis dermatitis and combined vascular diseases.