1.Comparison Between HLA-DR Serological Typing and O1igotyping.
Jai Ho WEE ; Ki Cheol JEONG ; Tai Gyeom KIM ; Jin Yeong HAN ; Jeong Man KIM
Korean Journal of Clinical Pathology 1997;17(6):1089-1099
BACKGROUND: In renal transplantation, a good HLA-DR match Is associated with successive graft outcome. But due to a number of technical problems, reliable serological DR typing cannot always be obtained. To compare the serological DR typing with DRBI DNA typing, we tested 103 specimens that had been frozen after serological typing, by PCR-SSOP typing method. METHODS: Serological DR typing was performed by complement-dependent microlymphocytotoxicity technique using commercial antisera kits, and DNA gyp ins was performed by PCR-SSOP, using one of the methods recommended by 12th International Histocompatibility Workshop. DNA amplification was done by DRBAMP-A and DRBAMP-B primers, and hybridization by 18 oligonucleotides labelled with digoxigenin.. RESULTS: The concordance rate between serologic typing and DNA typing was 76.7%. Most (79.0%) of discordant results were due to serological blanks turning out to be definable antigens by DNA typing and these antigens consisted of mainly DR5 splits but none of DR1, DR2, or DR7. CONCLUSIONS: In spite of technical improvement, serological typing method often can not define the accurate HLA-DR type. It is thought that combining serological typing with DNA typing Is necessary to achieve a higher success rate of graft outcome.
Digoxigenin
;
DNA
;
DNA Fingerprinting
;
Education
;
Histocompatibility
;
HLA-DR Antigens*
;
Immune Sera
;
Kidney Transplantation
;
Oligonucleotides
;
Transplants
2.Combination Chemotherapy with High Dose Cisplatin - Cyclophosphamide in Primary Epithelial Ovarian Cancer.
Jeong Sup YUN ; Ha Jeong KIM ; Sung Kyoo JANG ; Ki Hyung KIM ; Man Soo YOON
Korean Journal of Gynecologic Oncology and Colposcopy 2001;12(1):12-22
OBJECTIVE: The purpose of this study was to evaluate the therapeutic efficacy and toxicity of high dose cisplatin-cyclophosphamide combination chemotherapy on patients with primary epithelial ovarian cancer. METHODS: A review of 63 patients previously diagnosed as primary epithelial ovarian cancer after initial operation and histology at Pusan National University Hospital from Jul. 1993 to Jun, 1997 was performed. Patients were received the combination chemotherapy including cisplatin 100mg/m2/day and cyclophosphamide 750mg/m2/day, repeated 6 cycles every 4 weeks. The mean age was 48 years old, and previous surgical procedures were total abdominal hysterectomy and bilateral salpingo-oophorectomy with omentectomy. The patients were classified into FIGO stage and pathologic results. RESULTS: The clinical response rate was 100% in the FIGO stage Ic patients with PC combination chemotherapy, 100% in stage II, 53.5% in stage III, and 25% in stage IV. The overall response rate was 69.8%. The 3-year survival rate according to the treatment groups was 93.3% in stage Ic group, 60% in stage II, 50% in stage III and 0% in stage IV. The mean survival duration was 34.6 months. Hematologic toxicities in cisplatin-cyclophosphamide chemotherapy were neutropenia and anemia. Nausea and vomiting were the most common side effects and occurred in 96.8%. Most of the toxicities were grade 1 and 2. CONCLUSION: The combination chemotherapy with cisplatin-cyclophosphamide is relatively safe and effective method in the treatment of primary epithelial ovarian cancer.
Anemia
;
Busan
;
Cisplatin*
;
Cyclophosphamide*
;
Drug Therapy
;
Drug Therapy, Combination*
;
Humans
;
Hysterectomy
;
Middle Aged
;
Nausea
;
Neutropenia
;
Ovarian Neoplasms*
;
Survival Rate
;
Vomiting
3.Sclerosing Polycystic Adenosis of the Parotid Gland: A Case Report.
Byung Joo JEONG ; Mi Ran KIM ; Zhe Long LIANG ; Bon Seok KOO ; Jin Man KIM
Korean Journal of Pathology 2011;45(Suppl 1):S79-S83
Sclerosing polycystic adenosis (SPA) of the salivary glands is a rare entity analogous to fibrocystic disease of the breast. Less than 50 cases of SPA have been published in the literature. We report the first Korean case of SPA of the right parotid gland. A 34-year-old man presented with a slowly growing right parotid mass. Computed tomography showed a relatively well-demarcated, heterogeneously enhancing mass with multiple small calcifications. Fine needle aspiration showed cohesive sheets of epithelial cells with granular oncocytic cytoplasm and scattered lymphocytes. The parotidectomy specimen showed a 3 cm-sized solid nodular lesion with small cysts. Microscopically, the lesion was an unencapsulated mass of sclerotic fibrous tissue with cystic ducts, multiple calcifications, and lymphoplasma cell infiltration. Sclerosing adenosis and cystic ducts with frequent apocrine-like cells were noted. Familiarity with the cytologic and histological features of SPA is very important making the correct diagnosis.
Adult
;
Biopsy, Fine-Needle
;
Breast
;
Cystic Duct
;
Cytoplasm
;
Epithelial Cells
;
Humans
;
Lymphocytes
;
Parotid Gland
;
Recognition (Psychology)
;
Salivary Glands
4.Sclerosing Polycystic Adenosis of the Parotid Gland: A Case Report.
Byung Joo JEONG ; Mi Ran KIM ; Zhe Long LIANG ; Bon Seok KOO ; Jin Man KIM
Korean Journal of Pathology 2011;45(Suppl 1):S79-S83
Sclerosing polycystic adenosis (SPA) of the salivary glands is a rare entity analogous to fibrocystic disease of the breast. Less than 50 cases of SPA have been published in the literature. We report the first Korean case of SPA of the right parotid gland. A 34-year-old man presented with a slowly growing right parotid mass. Computed tomography showed a relatively well-demarcated, heterogeneously enhancing mass with multiple small calcifications. Fine needle aspiration showed cohesive sheets of epithelial cells with granular oncocytic cytoplasm and scattered lymphocytes. The parotidectomy specimen showed a 3 cm-sized solid nodular lesion with small cysts. Microscopically, the lesion was an unencapsulated mass of sclerotic fibrous tissue with cystic ducts, multiple calcifications, and lymphoplasma cell infiltration. Sclerosing adenosis and cystic ducts with frequent apocrine-like cells were noted. Familiarity with the cytologic and histological features of SPA is very important making the correct diagnosis.
Adult
;
Biopsy, Fine-Needle
;
Breast
;
Cystic Duct
;
Cytoplasm
;
Epithelial Cells
;
Humans
;
Lymphocytes
;
Parotid Gland
;
Recognition (Psychology)
;
Salivary Glands
5.The clinical aspects of pulmonary tuberculosis patient failed in retreatment.
Young Jae IM ; Ju Young SONG ; Jae Man JEONG ; Young Jun KIM ; Moon Shik KIM
Tuberculosis and Respiratory Diseases 1993;40(4):404-410
No abstract available.
Humans
;
Retreatment*
;
Tuberculosis, Pulmonary*
6.A Case of Mucoepidermoid Carcinoma in Pulmonary Tuberculosis Patient.
Jae Man JEONG ; Ju Young SONG ; Jae Rack HONG ; Young Jun KIM ; Moon Shik KIM
Tuberculosis and Respiratory Diseases 1994;41(4):429-434
Mucoepidermoid carcinoma of lung are rare carcinoma arising from the submucosal glands tissue of the proximal tracheobronchial tree. The carcinoma can be divided into low grade and high grade varienties. The most important factors in the prognosis include histological grading and the ability to achieve a complete surgical resection. We experienced a case of high grade mucoepidermoid carcinoma in pulmonary tuberculosis patient of 67 years old male who has been suffered from left chest pain for several weeks. He was not treated and died seventeen months later.
Carcinoma, Mucoepidermoid*
;
Chest Pain
;
Humans
;
Lung
;
Male
;
Prognosis
;
Trees
;
Tuberculosis, Pulmonary*
7.Ovarian Artery Rupture Presenting with a Spontaneous Retroperitoneal Hemorrhage of an Anticoagulated Patient: A Successful Treatment with Embolization
So Jeong LEE ; Min Jeong CHOI ; Bong Man KIM ; Sang Yoon KIM
Journal of the Korean Radiological Society 2020;81(6):1453-1458
Retroperitoneal hemorrhage is a potentially lethal complication in patients on anticoagulant therapy and can be caused by ovarian artery bleeding, regardless of the patients’ age and obstetric history. This case illustrates the clinical presentation of ovarian artery bleeding in a postmenopausal female on anticoagulant therapy, the diagnostic utility of transcatheter angiography, and successful embolization.
8.MR imaging in Moyamoya disease: utility of partial flip angle T2- weighted spin-echo imaging.
Kee Hyun CHANG ; Moon Hee HAN ; Jeong Geun YI ; In One KIM ; Man Chung HAN
Journal of the Korean Radiological Society 1991;27(4):479-484
No abstract available.
Magnetic Resonance Imaging*
;
Moyamoya Disease*
9.Factors Influencing Depression among Nursing Students.
Su Jeong YU ; Mi Ryeong SONG ; Eun Man KIM
Journal of Korean Academic Society of Nursing Education 2014;20(1):71-80
PURPOSE: The purpose of this study was to investigate the level and factors influencing depression among nursing students. METHODS: The data were collected from nursing students attending 3 universities who expressed a willingness to participate in the study through a questionnaire which surveyed them about depression, stress, social support, self-efficacy, self-esteem, and wellbeing in May, 2012. The collected data from 235 nursing students were analyzed using a SPSSWIN 19.0. RESULTS: The mean score of depression (using MDI) among nursing students was 16.7, which denotes a minor depressive mood. 49.1% of variance with regard to depression among nursing students was explained by stress, self-esteem, wellbeing and self-efficacy. CONCLUSION: There is a need to develop a depression prevention program for nursing students and to reduce stress and increase self-esteem, wellbeing and self-efficacy in order to establish an effective program.
Depression*
;
Humans
;
Surveys and Questionnaires
;
Students, Nursing*
10.Clinical Usefulness of Phase-Contrast Cine MRI Evaluation in Patients with Cervical Myelopathy.
Jeong Hwan LIM ; Jun Hyeok SONG ; Kyu Man SHIN ; Sung Hak KIM
Journal of Korean Neurosurgical Society 2000;29(12):1634-1641
No abstract available.
Humans
;
Magnetic Resonance Imaging, Cine*
;
Spinal Cord Diseases*