1.Analysis of Intermediate Term Results of Short Vein Bypass Graft in the Patient with Critical Limb Ischemia.
Hyo Sin KIM ; Hong Joo SEO ; Jeong Hwan CHANG
Vascular Specialist International 2014;30(1):26-32
PURPOSE: Since the introduction of short vein bypass (SVB), many have reported its feasibility when long vein bypass (LVB) cannot be performed due to limited vein conduit. However, the presence of inflow-vessel disease may affect graft patency and thus require endovascular treatment prior to surgery. Our study aims to analyze the results between SVB and LVB. MATERIALS AND METHODS: From 2009 to 2013, 27 bypass procedures were reviewed retrospectively. Outcomes such as patency rate, postoperative ankle brachial index (ABI) and limb salvage rate between SVB and LVB were compared. Wound healing time and primary patency rate were analyzed and the former was also analyzed according to the respective angiosome and revascularization type. RESULTS: There were 11 males and 16 females and the mean age was 66.6+/-12.3 years. Twenty four patients had TransAtlantic Inter-Society Consensus (TASC) D and 3 patients had TASC C lesions below knee. The 1-year cumulative patency rate between SVB and LVB were 63% and 66%, P=0.627. The limb salvage rate (100% vs. 73%; P=0.280) and postoperative ABI (0.592 vs. 0.508; P=0.620) were higher in the SVB group than in the LVB group, although the differences were not significant. There was no difference in wound healing time by angiosomal revascularization type. In situ vein graft showed higher patency rate than reversed greater saphenous vein (75% vs. 61%; P=0.00) CONCLUSION: The results of SVB were similar to those of LVB. SVB is feasible in the setting of limited conduit availability, in combination with endovascular treatment in the presence of proximal lesions.
Ankle Brachial Index
;
Consensus
;
Extremities*
;
Female
;
Humans
;
Ischemia*
;
Knee
;
Limb Salvage
;
Male
;
Retrospective Studies
;
Saphenous Vein
;
Transplants*
;
Veins*
;
Wound Healing
2.A Study on Photopatch Test in Photodermatoses.
Joo Eun JANG ; Jeong Hee HAHM ; Hong Il KOOK
Korean Journal of Dermatology 1983;21(5):531-536
It is believed that the photopatch test is a valuable screening procedure for the determination of responsible antigenic substances in photoallergic contact dermatitis. But the technigues used for this procedure are cumbersome and require expensive equipment. In the present study, we adapted an easy and inexpensive photopatch test met- hod to our need. We report the results of this test method which was performed. in 21 patients with photodermatitis and 9 patients with polymorphic light eruption. 1. The UVB sensitivity determined by minimal erytherna dose (mean+-standard deviation) was I1618mW sec/cm in photodermatitis group, 108+ROmW sec/cm in polymorphic light eruption group and 126-+32mW-sec/cm in control group. But there was no significant difference among them (p>0. 05). 2. The reaction to UVA were negative in all groups. R. The photopatch test using IO potential photosensitizers revealed 12 positive responses in 9 patients; including 7 patients in photodermatitis group and 2 patients in polymorphic light eruption group. And the number of positive photopatch responses obtaied with each photosensitizer in RO patients with photodermatoses was 5 in chlorhexidine, 2 in paraaminobenzoic acid, musk ambrette and bithionol and 1 in chlorpromazine, respectively.
Bithionol
;
Chlorhexidine
;
Chlorpromazine
;
Dermatitis, Photoallergic
;
Humans
;
Mass Screening
;
Photosensitivity Disorders
;
Photosensitizing Agents
3.Replacement of the TMJ disc with deep temporal fascial flap.
Jeong Gu LEE ; Hong Bum SOHN ; Dong Joo LEE ; Kwang Jin HONG ; Byong Jin MIN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):199-206
No abstract available.
Temporomandibular Joint*
4.Replacement of the TMJ disc with deep temporal fascial flap.
Jeong Gu LEE ; Hong Bum SOHN ; Dong Joo LEE ; Kwang Jin HONG ; Byong Jin MIN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):199-206
No abstract available.
Temporomandibular Joint*
5.A Case of Tetrasomy 9P.
Jeong Hae JOO ; Hong Sun JOO ; Son Sang SEO ; Sook Ja PARK
Journal of the Korean Society of Neonatology 1997;4(1):72-76
Supernumerary isochromosome resulting in autosomal tetrasomy are rare and have been described only for 12P, 18P, and 9P. Tetrasomy 9P, initially described by Ghymer et al, is a rare chromosomal aberration that has been described in 20 patients. Affected subjects show both cytogenetic and ohenotypic variability. Some patients have the abnormal cell line in all cells, but many display tissue limited mosaicism. The phenotype varies in severity from prenatal death to mild developmental delay and minor anomalies. We reported a infant with mild manifestations of tetrasomy 9p with brief review of related literatures.
Cell Line
;
Chromosome Aberrations
;
Cytogenetics
;
Humans
;
Infant
;
Isochromosomes
;
Mosaicism
;
Phenotype
;
Tetrasomy*
6.A Case of Dermatomyofibroma in a 2-year-old Boy.
Soo Hong KIM ; Jeong Joon OH ; Joo Heung LEE ; Eil Soo LEE
Annals of Dermatology 2003;15(2):68-70
Dermatomyofibroma is a rare benign dermal tumor, mainly found in young women. Clinically it can be confused with keloid or dermatofibrosarcoma protuberans. Typical histopathologic features of dermatomyofibroma are sufficiently distinctive to alert histopathologists to consider dermatomyofibroma in the diagnostic process. We report a case of dermatomyofibroma, presenting as reddish plaques and nodules on the buttock of a 2-year-old boy. Histopathologic examination showed fascicles of uniform spindle cells in the reticular dermis, predominantly oriented parallel to the epidermal surface. Immunohistochemical study and electron microscopy confirmed its myofibroblastic nature.
Buttocks
;
Child
;
Child, Preschool*
;
Dermatofibrosarcoma
;
Dermis
;
Female
;
Humans
;
Keloid
;
Male*
;
Microscopy, Electron
;
Myofibroblasts
7.Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection.
Yu Hyeon CHOI ; Hyung Joo JEONG ; Bongjin LEE ; Hong Yul AN ; Eui Jun LEE ; June Dong PARK
Korean Journal of Critical Care Medicine 2017;32(2):211-217
Acute cerebral infarctions are rare in children, however, they can occur as a complication of a Mycoplasma pneumoniae (MP) infection due to direct invasion, vasculitis, or a hypercoagulable state. We report on the case of a 5-year-old boy who had an extensive stroke in multiple cerebrovascular territories 10 days after the diagnosis of MP infection. Based on the suspicion that the cerebral infarction was associated with a macrolide-resistant MP infection, the patient was treated with levofloxacin, methyl-prednisolone, intravenous immunoglobulin, and enoxaparin. Despite this medical management, cerebral vascular narrowing progressed and a decompressive craniectomy became necessary for the patient's survival. According to laboratory tests, brain magnetic resonance imaging, and clinical manifestations, the cerebral infarction in this case appeared to be due to the combined effects of hypercoagulability and cytokineinduced vascular inflammation.
Brain
;
Cerebral Infarction*
;
Child
;
Child, Preschool
;
Decompressive Craniectomy
;
Diagnosis
;
Enoxaparin
;
Humans
;
Immunoglobulins
;
Inflammation
;
Levofloxacin
;
Magnetic Resonance Imaging
;
Male
;
Mycoplasma pneumoniae*
;
Mycoplasma*
;
Pneumonia, Mycoplasma*
;
Stroke
;
Thrombophilia
;
Thrombosis
;
Vasculitis
8.PAX2 Expression in Renal Dysplasia.
Yoon Hee LEE ; Woo Hee JUNG ; Soon Won HONG ; Hyeon Joo JEONG
Korean Journal of Pathology 2007;41(2):69-78
BACKGROUND: Renal dysplasia is the abnormal development of the kidney. The condition is usually detected in childhood along with other urinary tract anomalies, but can remain unnoticed until adulthood. It was recently reported that a PAX2 gene mutation plays a major role in the development of renal dysplasia. The aim of this study was to examine the expression of PAX2 in dysplastic kidneys of children and adults. METHODS: A total of 30 cases diagnosed with renal dysplasia after a nephrectomy were examined. PAX2 expression was evaluated using immunohistochemistry. Apoptosis was detected using an Apop Tag detection kit. RESULTS: In the dysplastic kidneys, there was strong PAX2 expression in the epithelia of the primitive ducts in both children and adults, but the degree was significantly lower in adults (p=0.007). However, the mesenchyme surrounding the primitive ducts of children showed stronger staining for the smooth muscle actin antibody and trichrome than the adults. The apoptosis index was significantly higher in the primitive duct epithelia than in the surrounding normal collecting duct epithelia (p=0.000). CONCLUSIONS: PAX2 is overexpressed in the primitive ducts of renal dysplasia, which is sustained until adulthood and is associated with increased apoptosis. However, a decrease in PAX2 expression in the dysplastic epithelia and mesenchymal cuff of adults suggest a gradual regression of the dysplastic elements with time.
Actins
;
Adult
;
Apoptosis
;
Child
;
Humans
;
Immunohistochemistry
;
Kidney
;
Mesoderm
;
Muscle, Smooth
;
Nephrectomy
;
Urinary Tract
9.Clinical Manifestation and Therapeutic Effect of Azathioprine in Lupus Nephritis of Children.
Ji Suk LEE ; Ji Hong KIM ; Jae Seung LEE ; Pyung Kil KIM ; Hyun Joo JEONG
Korean Journal of Nephrology 1998;17(6):879-886
PURPOSE: The incidence of clinical nephritis is much higher especially in younger ages and in about one half of the cases, it also shows nephrotic syndrome. Thus, we examine the clinical and pathologic consideration of children with lupus nephritis and their treatment modality to improve the prognosis. MATERIAL AND METHOD: Among 67 cases of children under eighteen who were diagnosed SLE, 50 patients with hematuria and proteinuria from Jan. 1980 to Dec. 1996 were selected for the review. RESULTS: The ratio of the male to female patient was 1:3.5 and the average age at the diagnosis was 11.85+/-3.2 years old. Most common clinical manifestations at the time of the diagnosis were fever and skin rashes and the common laboratory results were proteinuria, hematuria, Out of 50 cases, 33 cases had renal biopsy. The results were 17 cases of Class IV, 7 cases of Class lll, 5 cases of Class lll, 3 cases of Class V and 1 case of Class l. Different treatment modalities were carried out; Corticosteroid only 21 cases, Corticosteroid+Azathioprine 25 cases, Corticosteroid+Cyclophosphamide 3 cases, and Corticosteroid+Cyclosporine A 1 case. However, there were no significant difference in the recurrence and complete remission rate of lupus nephritis in between each treatment groups. Average follow-up period was 37+/-23 months. Of all the follow-ups, 7 patients were dead. CONCLUSION: Early diagnosis should be carried out with renal biopsy, and should be considered for vigorous therapy, which currently includes high doses of corticosteroids and immunosuppressive drugs. Among these immunosuppressive agents, azathioprine has a lower incidence of long-term complications and low costs might be recommended. In addition, regular check-up for anti-DNA antibody, serum complement concentration and appropriate moniroting and management for the adverse effects of the treatment should enable to reach the continuous remission.
Adrenal Cortex Hormones
;
Azathioprine*
;
Biopsy
;
Child*
;
Complement System Proteins
;
Diagnosis
;
Early Diagnosis
;
Exanthema
;
Female
;
Fever
;
Follow-Up Studies
;
Hematuria
;
Humans
;
Immunosuppressive Agents
;
Incidence
;
Lupus Nephritis*
;
Male
;
Nephritis
;
Nephrotic Syndrome
;
Prognosis
;
Proteinuria
;
Recurrence
10.Azathioprine Therapy in Henoch-Schonlein Purpura Nephritis Accompanied by Nephrotic syndrome.
Hyeon Joo JEONG ; Pyung Kil KIM ; Ji Hong KIM ; Jin Tae SON
Journal of the Korean Society of Pediatric Nephrology 1998;2(1):41-49
In 1989, the Bethesda System (TBS) was introduced as an attempt to standardize cervical/vaginal reporting systems. TBS nomenclature was created for reporting cytologic diagnoses to replace the currently used Cervical Intraepithelial Neoplasia (CIN) and Papanicolaou Class System, which are deemed less reproducible. The name for preinvasive squamous lesions was changed to squamous intraepithelial lesion (SIL), subdivided into low-grade and high-grade types. TBS recommends a specific format for cytologic report, starting with explicit statement on the adequacy of the specimen, followed by general categorization and descriptive diagnosis. Pathologic and epidemiologic studies performed over last 10 years have provided evidence that human papillomavirus (HPV) plays a significant role in the development of cervical neoplasia. TBS corresponds not only to currently held views of the behavior of preinvasive lesions and their HPV distribution, but also to the current guidelines for clinical management.
Azathioprine*
;
Body Fluids
;
Cadherins
;
Cervical Intraepithelial Neoplasia
;
Diagnosis
;
Epidemiologic Studies
;
Humans
;
Immunohistochemistry
;
Nephritis*
;
Nephrotic Syndrome*
;
Purpura, Schoenlein-Henoch*