1.Clinical and Polysomnographic Characteristics of REM Sleep-Dependent Obstructive Sleep Apnea.
Yu Jin LEE ; Soon Jeong LEE ; Dong Jin KANG
Sleep Medicine and Psychophysiology 2008;15(2):77-81
INTRODUCTION: REM sleep which shows characteristic muscle atonia and increased resistance of upper respiratory track is known to be vulnerable to sleep apnea. Previous studies reported that REM sleep-dependent (or related) obstructive sleep apnea syndrome (REM-dependent OSA) could be one of sleep disordered breathing. The present study aimed to investigate clinical findings and polysomnographic variables of REM-dependent OSA. METHODS: Fifty-six patients diagnosed with mild to moderate obstructive sleep apnea by overnight polysomnography (5
Body Mass Index
;
Humans
;
Leg
;
Muscles
;
Oxygen
;
Polysomnography
;
Sleep Apnea Syndromes
;
Sleep Apnea, Obstructive
;
Sleep, REM
;
Track and Field
2.Sleep and Pain.
Sleep Medicine and Psychophysiology 2012;19(2):63-67
The reciprocal interaction between sleep and pain has been reported by numerous studies. Patients with acute or chronic pain often complain of difficulty falling asleep, frequent awakenings, shorter sleep duration, unrefreshing sleep, and poor sleep quality in general. According to the majority of the experimental human studies, sleep deprivation may produce hyperalgesic changes. The selective disruption of slow wave sleep has shown this effect more consistently, while results after selective REM sleep deprivation remain unclear. Patients with chronic pain have a marked alteration of sleep structure and continuity, such as frequent sleep-stage shifts, increased nocturnal awakenings, decreased slow wave sleep (SWS), decreased rapid eye movement (REM) sleep, and alpha-delta sleep. Many analgesic medications can alter sleep architecture in a manner similar to the effects of acute and chronic pain, suppressing SWS and REM sleep.
Chronic Pain
;
Humans
;
Sleep Deprivation
;
Sleep, REM
3.Clinical trial of myocardial protection using cold oxygenated diluted blood cardioplegia in child age.
The Korean Journal of Thoracic and Cardiovascular Surgery 1992;25(3):211-219
No abstract available.
Child*
;
Heart Arrest, Induced*
;
Humans
;
Oxygen*
5.Sleep Fragementation Decreases during the nCPAP Titration Night in Obstructive Sleep Apnea Syndrome.
Sleep Medicine and Psychophysiology 2008;15(2):82-86
OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) not only causes respiratory disturbances during sleep but also decreases the quality of nocturnal sleep through sleep fragmentation and sleep structure change. We aimed at comparing the changes in sleep fragmentation and structure between baseline (diagnostic) nocturnal polysomnography (NPSG) and nCPAP (nasal continuous positive airway pressure) titration trial. METHODS: One hundred and three patients with a baseline night of respiratory disturbance index (RDI) of 5 or greater and reduced RDI score during nCPAP titration night were retrospectively selected for the study. Sleep fragementation and sleep structure between baseline NPSG and the NPSG during nCPAP titration were compared. Sleep fragmentation index (SFI) was defined as the total number of awakenings and shifts to stage 1 sleep divided by the total sleep time in hour. SFI and other polysomnographic parameters were statistically compared between the two nights. RESULTS: SFI during baseline NPSG and nCPAP titration nights were 29.0+/-13.8 and 15.2+/-8.8, respectively, indicating a significant SFI decrease during nCPAP titration (t=9.7, p<0.01). SFI showed significant negative correlations with sleep efficiency (r=-0.60, p<0.01) and total sleep time (r=-0.45, p<0.01) and a positive correlation with RDI (r=0.28, p<0.01). CONCLUSION: Use of nCPAP, even during the titration, significantly decreases sleep fragmentation and improves sleep structure in OSAS patients. We suggest that SFI may be utilized as a measure of assessing OSAS severity and nCPAP efficacy.
Humans
;
Polysomnography
;
Retrospective Studies
;
Sleep Apnea, Obstructive
;
Sleep Deprivation
6.Sleep-Related Behaviors during Nocturnal Sleep.
Sleep Medicine and Psychophysiology 2006;13(1):11-14
Sleep-related behaviors observed in parasomnias can result in serious injuries of patients and/or spouses. Parasomnia is defined as undesirable physical or behavioral phenomenon occurring during sleep. If these disorders are accurately diagnosed, effective treatments are available. Often, these disorders can be even cured. Environmental management for patient and/or spouse safety and good sleep hygiene are the most recommended for individuals behaving abnormally during sleep. The aim of this article is to review the clinical features, diagnosis and treatment of several sleep-related behavior disorders.
Diagnosis
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Humans
;
Hygiene
;
Mental Disorders
;
Parasomnias
;
Spouses
7.Bactericidal Activity of Thrombin - induced Platelet Microbicidal Protein Against Streptococcus rattus BHT.
Si Young LEE ; Jeong Sook LEE ; Son Jin CHOE
Journal of Bacteriology and Virology 2001;31(4):317-324
No abstract available.
Animals
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Blood Platelets*
;
Butylated Hydroxytoluene*
;
Rats*
;
Streptococcus*
;
Thrombin*
8.Nongestational Choriocarcinoma of the Overy.
Jeong Hee KANG ; Hae Jin LEE ; Sun Kyung LEE
Korean Journal of Pathology 1993;27(5):514-517
Most instances of choriocarcinoma of the ovary are gestational in origin. In contrast, nongestational choriocarcinoma of the ovary is an exceedingly rare primary germ cell neoplasm that has worse prognosis than gestational neoplasm. We report a case of pure nongestational choriocarcinoma of the ovary in view of the rarity of its kind. The patient was a 35-year-old Korean unmarried woman who had suffered from vaginal bleeding and feeling of abdominal inflation for two months. The X-ray studies and CT scanning revealed a child head sized cystic mass on the right pelvic cavity and multiple nodular densities in both lung fields and the liver. The mass in pelvic cavity was excised and histologically confirmed to be a nongestational pure choriocarcinoma, arising from the right side ovary.
Child
;
Male
;
Female
;
Humans
9.Analytical Evaluation for Serum CK-MB Measurements.
Jeong Rim LEE ; Woo In LEE ; Jin Tae SUH
Korean Journal of Clinical Pathology 1997;17(5):718-724
No abstract available.
10.Analytical Evaluation for Serum CK-MB Measurements.
Jeong Rim LEE ; Woo In LEE ; Jin Tae SUH
Korean Journal of Clinical Pathology 1997;17(5):718-724
No abstract available.