To evaluate correlation between the expression of neu and ras oncoprotein and epidermal growth factor receptor on breast carcinoma and other known prognostic factors, immunohisto-chemical studies were performed. Positive reaction for neu, which appeared as brown granular deposits along cell surface and cytoplasm of the tumor cells, was significantly correlated with the histological grade but not with other prognostic factors such as tumor size, lymph node me-tastasis, local recurrence, and estrogen and progesteron receptor status. Also granular deposits of ras were noted in the carcinoma cells in the cytoplasm, while the epithelaial cells of the normal lobule and duct showed negative reation. But expression of ras was not significantly associated ras with other prognostic factors. The reaction for EGFR was mostly negative on epithelial cells of both the normal lobule and duct, and was not significantly associated with other prognostic factors. The results suggested that expression of the neu oncoprotein is significantly associated with the histological grade of breast carcinoma, while the ras and the EGFR do not show significant prognostic value.
Breast Neoplasms

This descriptive study measured the quality of life and the sexual satisfaction for ostomates as an attempt to give nurses basic data to improve life satisfaction of ostomates. The research design was a descriptive study and the data were obtained by Quality of Life questionnaire, and Sexual Satisfaction questionnaire. These data were collected from 21 ostomates undergoing treatment in four university hospitals and one hospital and 36 ostomates depending on one medical agency by direct obtaining method and mailing method from March. 3, to March 24,1997. Data analysis was cone by the SAS computer program and Descriptive statistics, Pearson correlation Coefficient, and Cronbach-alpha were used. The results of this study were as follows : 1. The item mean score for quality of life for the ostomates was 3.03. For six subscales in the quality of life scale, the mean scores of subscales were in order of the highest 3.46 for family relationship, and the second scored subscales were economic life(2.84) and physical state(2.96). 2. The item mean score of sexual satisfaction for the ostomate was 2.86. 3. The result of analysis of relationship between quality of life and sexual satisfaction was significant(r=0.21, p=0.05). The relationship between sexual satisfaction and each subscale of quality of life were significant with the self-esteem (r=0.34, p=0.01), physical state(r=0.21, p=0.01). In conclusion, it was found that the quality of life and sexual satisfaction of ostomates were low. The quality of life and sexual satisfaction was correlated. Although chronic disease affect to quality of life and sexual satisfaction, an adequate nursing intervention will improve the life satisfaction.
Chronic Disease ; Family Relations ; Hospitals, University ; Nursing ; Postal Service ; Quality of Life* ; Research Design ; Statistics as Topic ; Surveys and Questionnaires

During the period of May 10 to June 6, 1987, we have conducted the survey about the number of the food daily taken and the in take of nutrition of the 83 pregnant women who have registered at Sudong Myun and Mikum-myun, Yangchu-gun which are demonstration are of the public health and medicine of the College of Medicine, Ewha Women's University, and of the 100 pregnant women who have been to the University Hospital attached to the above School. The result of the survey is as follows: 1) Among the above pregnant women, primigravida constituted 91 women and multigravida 92 women. As for the month of pregnancy, those who have been pregnant for ten months numbered 43 women (23.5%), which was the highest number. As for age, those who were 25 to 29 years old constituted 63.9%, which was the highest in percentage. 2) As for the level of education, those who graduated from high school constituted 49.2%, which was the highest in percentage. As for occupation, those who were entirely in charge of household affairs as housewives were 89.6%, which comprised most of the jobs held by the above women. 3) As for the composition of a family in environmental food and nutrition, one generation was 68.3%, and two member family was 42.6% which was the highest. As for those taking care of cooking and serving meals, housewives constituted 95.1%. 4) As for the economic situation of dietary life, those who were in the highest level (A level), were 47.0% in an urban area and 41.0% in rural area, which were the highest in percentage. 5) The food which the above people selected after being pregnant was fruit not only in an urban area, but also in a rural area. And in terms of the percentage of fruit, and urban area and a rural area showed 44.0% and 54.2% respectively. As for milk, and urban area and a rural area showed 28.0% and 8.4% respectively, which disclosed that the rate of a rural area was much lower than that of an urban area. 6) As for the number of food intake, 10-14 was 54.0% in an urban area, which was the highest. And 5-9 was 73.5% in a rural area, which was the highest. 7) As for the composition of food taken according to the number of food taken, meat showed the lowest rate in 5-9 group. (P<0.05) As the number of food taken increased, the rate of food taken(Points) increased (2.4). Milk and milk products showed al low rate in 5-9 group and 15-19 group (P<0.05). Fruit intake showed a similar rate in all groups. As for vegetables, the rate of intake was high, as the number of food taken increased. Cereals showed a similar rate in all troups. And the points of intake was high. As for fat, hte rate of intake was high, as the number of food taken increased. 8) In 5-9 group in the number of food intake, energy was 79.9% of RDA, protein was 64.9%, fat was 90.0%, carbohydrate was 81.6%, iron was 83.0%, calcium was 71.1%, vitamin A was 94.3%, vitamin B1 was 77.8%, vitamin B2 was 79.2%, and vitamin C was 88.2%, so that it showed the lowest sufficiency rate of RDA. 15-19 group maintained the balance in energy and all nutrients nearly. In 20-24 group, fat was 142.4%, vitamin B2 was 105.6% and vitamin C was 102.2%, so that it exceeded RDA.
Adult ; Ascorbic Acid ; Calcium ; Edible Grain ; Cooking ; Eating* ; Education ; Family Characteristics ; Female ; Fruit ; Humans ; Iron ; Meals ; Meat ; Milk ; Occupations ; Pregnancy ; Pregnant Women ; Public Health ; Riboflavin ; Thiamine ; Vegetables ; Vitamin A

PURPOSE: The purpose of this study was to investigate the factors influencing health promotion behavior of fire officers in Korea. METHODS: It was a descriptive study. The subjects were comprised of 104 fire officers by self-reported questionnaires from January to February 2012. The instruments used for this study were a health belief, self-efficacy and health promotion lifestyle profile II. The data were analyzed using SPSS/WIN 14.0. RESULTS: The scores of health promotion behavior of fire officers were 2.76 (on a 4-point scale) and of health belief were 2.98 (on a 4-point scale), followed by perceived benefits at 3.45, perceived seriousness at 3.02, perceived sensitiveness at 2.82, perceived barriers at 2.23, and self-efficacy at 3.04 (on a 4-point scale). The health promotion behavior was very closely correlated with the health belief (r=0.49, p<.001). In the sub region, perceived benefit was correlated (r=0.28 p=.005) and the perceived seriousness (r=0.38, p<.001), the perceived sensitiveness (r=0.36, p<.001), and self-efficacy (r=0.55, p<.001) were correlated. Two significant variables influencing health promotion behavior of fire officer were self-efficacy and perceived seriousness (explained 41.0%). CONCLUSION: It suggested that self-efficacy and perceived seriousness should be considered when developing a fire officers's health promoting program.
Fires ; Health Promotion ; Life Style ; Surveys and Questionnaires

PURPOSE: This study was conducted to identify the present conditions of clinical practicum through analyzing guidebooks used in education institutions for oncology advanced practice nursing programs and to discuss future directions. METHODS: Ten of a total of 13 education institutions participated in this study and ten guidebooks were reviewed from June 1 to October 31, 2014. The standard curriculum developed by the Korean accreditation board of nursing education was used to analyze the present conditions and an analyzing frame was developed by a research team. Two coders independently recorded the data, agreement was 92% and all disagreements was concurrent after discussion. RESULTS: Courses in the area of 'advanced oncology nursing' were most highly established and, courses in the area of 'introduction of oncology nursing' were least established. Some learning objectives were never dealt with and some learning objectives were over dealt with. The national cancer center was most used for practicum. Diverse homework and evaluation methods were used. CONCLUSION: Through analyzing clinical practicum guidebooks for oncology advanced practice nursing students, we found that balanced practicum courses are needed to improve the quality of oncology advanced practice nurse programs.
Accreditation ; Advanced Practice Nursing* ; Curriculum ; Education ; Education, Nursing ; Humans ; Learning

No abstract available.
Holoprosencephaly* ; Prune Belly Syndrome*

The purpose of this study was to identify the effects of cancer prevention and early detection education on cancer-related knowledge, attitudes, and preventive health behavior of middle-aged women in Korea. The research design was a nonequivalent control group pretest-posttest design. The subjects of this study were 38 middle-aged women from a church in Taegu. An Experimental group of 19 and a control group of 19 women were studied. The study was conducted from September 21, 2000 to October 27, 2000. The cancer prevention and early detection education had been provided to the experimental group for 2 weeks. The contents of the education program for the third most prevalent cancer of Korean women were: 'the risk factors of cancer', 'the early symptoms of cancer', 'the diagnostic test for cancer detection', and 'the cancer prevention methods'. The instruments used for this study were modified, cancer-related knowledge, and attitude, preventive health behavior tools of Suh et al.(1998). Data were analyzed using descriptive statistics, X2-test, t-test, ANCOVA with SPSS WIN 9.0/PC. The results were as follows: 1) Hypothesis 1 that the women who get cancer prevention and early detection education will have higher scores of the cancer-related knowledge than the women do not get cancer prevention and early detection education was accepted(F=4.732, p=.037). 2) Hypothesis 2 that the women who get cancer prevention and early detection education will have higher scores of cancer-related attitudes than the women do not get cancer prevention and early detection education was rejected(F=.118, p=.733). 3) Hypothesis 3 that the women who get cancer prevention and early detection education will have higher scores of cancer-related preventive health behavior than the women who do not get cancer prevention and early detection education was rejected(F=2.250, p=.143). On the basis of the above findings, the following recommendations are suggested: 1)It is necessary to identify the variables affected on cancer-related knowledge, attitudes and preventive health behavior. 2) It is necessary to develop a well organized cancer prevention and early detection education program to change cancer-related attitude and preventive health behavior.
Daegu ; Diagnostic Tests, Routine ; Education* ; Female ; Health Behavior* ; Humans ; Korea* ; Research Design ; Risk Factors

PURPOSE: The purpose of this study was to identify the burden, health promotion behavior and health status and to describe the relationship of the burden, health promotion behavior and health status of the family caregivers of intensive care unit patients. METHOD: The subjects were 48 family caregivers of ICU patients in a University Hospital. Data were collected between June, 1 and July, 31, 2000 using structured questionnaires. Research tools used were Suh and Oh's Burden Scale, Revised Walker, Sechrist, and Pender's HPLP(1987) ; Revised Nam's Health State Scale(1965). RESULT: The mean score of burden of family caregiver was 3.01(full score was 5). The mean score of health promotion behavior of family caregiver was 2.52 (full score was 4). And the mean score of health status of family caregiver was 0.68(full score was 1.00). The score of psychological health state was a little higher than the physiological one. In correlational analysis, the burden and the health status of caregivers were reversely correlated . The correlation between the burden and the health promotion behavior, and the health behavior and health status were not significant. CONCLUSION: The more burden caregivers of ICU patients felt, the worse their health status. So nurses need to understand the family caregiver's burden and apply nursing care that can reduce burden, in order to improve the health status of family caregivers.
Caregivers* ; Health Behavior ; Health Promotion* ; Humans ; Intensive Care Units* ; Critical Care* ; Nursing Care ; Surveys and Questionnaires

Malignant lymphomas of the upper respiratory tract are relatively common in the Orient including Korea. They have a marked clinicopathologic and immunophenotypic diversity. We retrospectively reviewed 20 cases of malignant lymphomas with features of polymorphic reticulosis in the upper respiratory tract. Histopathologic findings consisted of polymorphism of lymphoid cells in 17 cases(85%), angiocentricity in 14 cases(70%), coagulation necrosis in 12 cases(60%), and epitheliotropism in 8 cases(40%). By Working Formulation, 14 cases(70%) were classified as diffuse large cell type, 4 cases(20%) as diffuse mixed small cleaved and large cell type, one case as immunoblastic type, and one case as anaplastic large cell type. On immunostaining, one showed B-cell phenotype and 19 cases showed T-cell phenotype. The B-cell type was histologically diffuse large cell type. From these results, we concluded that polymorphic reticulosis is a type of peripheral T-cell lymphoma with angiocentricity.

The significance of cervical erosion with benign cellular change on Papanicolaou smear has not been evaluated. A retrospective review of 430 coloscopically directed punch biopsies performed over 15 months revealed 206 cases who had a benign cellular change on cytologic smear. Of these 206 smears, 48(23%) had clear cervix without erosion, 99(48%) had mild erosion on cervix, 41(20%) had moderate cervical erosion and 18(9%) had severe cervical erosion. The false negative rate that revealed more than mild dysplasia on histologic diagnosis was 2% in patients without cervical erosion, 3% in patients with mild cervical erosion, 5 % in patients with moderate cervical erosion, and 11% in patients with severe cervical er- osion. Koilocytotic change that suggested human papilloma virus infection was 17% in each group regardless cervical erosion. In conclusion, benign cellular change on Pap smears in patients with severe cervical erosion may be associated with significant cervical cancer pathology.
Biopsy ; Cervix Uteri ; Diagnosis ; Female ; Humans ; Papanicolaou Test* ; Papilloma ; Pathology ; Retrospective Studies ; Uterine Cervical Neoplasms